Compound ID	Pharmacological profile	Compound name	Binding data	Activity data	Bibliographic ref	Cross-reactivity
CHEMBL134834	agonist	HX640	Ki = 1000 nM		PMID: 9435893	RXR_alpha
CHEMBL298373	antagonist	LE540	Ki = 1500 nM		PMID: 9435893	RXR_alpha
CHEMBL308377	agonist	Compound 3	Kd = 180 nM	EC50 = 6 nM	PMID: 11428923	RXR_alpha
CHEMBL308883	agonist	Compound 6	Kd = 42 nM	EC50 = 71 nM	Bioorg. Med. Chem. Lett. 1996, 6, 2, 213	RXR_alpha
CHEMBL326525	antagonist	HX531		IC50 = 0.38 +/- 0.14 µM	PMID: 19095448	RXR_alpha
CHEMBL334330	agonist	HX600	Ki = 1000 nM		PMID: 9435893	RXR_alpha
CHEMBL334428	agonist	HX641	Ki = 170 nM		PMID: 9435893	RXR_alpha
CHEMBL334534	agonist	HX620	Ki = 2100 nM		PMID: 9435893	RXR_alpha
CHEMBL337859	agonist	HX630	Ki = 620 nM		PMID: 9435893	RXR_alpha
CHEMBL69091	agonist	Compound 5	Kd = 1.8 nM	EC50 = 1.0 nM	Bioorg. Med. Chem. Lett. 1996, 6, 2, 213	RXR_alpha
CHEMBL75133	agonist	Compound 2	Kd = 3.8 nM	EC50 = 0.08 nM	PMID: 11428923	RXR_alpha
CHEMBL89241	agonist	LG100567	Ki = 9.3 +/- 1.5 nM	EC50 = 77 +/- 26 nM	PMID: 8709094	RXR_alpha
ZINC01539543	agonist	Compound 3		EC50 = 105 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RAR_beta
ZINC01539579	agonist	targretin	Ki = 29 nM	EC50 = 25 nM	Bioorg. Med. Chem. Lett. 1997, 7, 21, 2747	RAR_gamma
ZINC01546069	agonist	Compound 6b	Ki = 5 nM	EC50 = 7 nM	Bioorg. Med. Chem. Lett. 1997, 7, 21, 2747	RXR_alpha
ZINC01895566	agonist	Compound 14b		relative EC30 = 0.033	PMID: 9703470	RXR_alpha
ZINC01997144	agonist	Compound 18	Ki = 238 nM	EC50 = 254 nM	PMID: 10052980	RXR_alpha
ZINC02008474	agonist	Compound 5a	Kd = 8 nM	EC50 = 14 nM	PMID: 12482435	RAR_alpha
ZINC03834061	agonist	Compound 3	Ki = 5 nM	EC50 = 7 nM	PMID: 10052980	RXR_alpha
ZINC03834062	agonist	Compound 9	Ki = 57 nM	EC50 = 28 nM	PMID: 10052980	RXR_alpha
ZINC03834065	agonist	Compound 14	Ki = 12 nM	EC50 = 11 M	PMID: 10052980	RXR_alpha
ZINC03834066	agonist	Compound 5	Ki = 57 nM	EC50 = 32 nM	PMID: 10052980	RXR_alpha
ZINC03834068	agonist	Compound 8	Ki = 42 nM	EC50 = 9 nM	PMID: 10052980	RXR_alpha
ZINC03834070	agonist	TTCNB	Ki = 299 nM	EC50 = 246 nM	PMID: 10052980	RAR_gamma
ZINC03834071	agonist	Compound 10	Ki = 224 nM	EC50 = 99 nM	PMID: 10052980	RXR_beta
ZINC03834076	agonist	Compound 6	Ki = 5051 nM	EC50 = 2894 nM	PMID: 10052980
ZINC04632539	agonist	Compound 7	Ki = 558 nM	EC50 = 206 nM	PMID: 10052980	RXR_beta
ZINC04821771	agonist	Compound 4	Ki = 8 nM	EC50 = 4 nM	PMID: 10052980	RXR_alpha
ZINC12358651	agonist	ATRA	IC50 = 350 +/- 40 nM	EC50 = 1100 +/- 85 nM	PMID: 8308867	PPAR_gamma
ZINC12661824	agonist	9 cis-retinoic acid	IC50 = 4 +/- 2.0 nM	EC50 = 140 +/- 13 nM	PMID: 8308867	RAR_alpha
ZINC13487075	agonist	Compound 5b	Kd = 153 nM	EC50 = 36 nM	PMID: 12482435	RXR_alpha
ZINC13487076	agonist	Compound 8	Kd = 6 nM	EC50 = 24 nM	PMID: 12482435	RXR_alpha
ZINC13734373	agonist	3-ethyl-TTNPB	IC50 = 10 +/- 6.0 nM	EC50 = 2900 +/- 250 nM	PMID: 8308867	RAR_alpha
ZINC13734376	agonist	3-isopropyl-TTNPB	IC50 = 10 +/- 4.0 nM	EC50 = 300 +/- 32 nM	PMID: 8308867	RXR_alpha
ZINC13738449	agonist	Compound 12a	Ki = 290 nM	EC50 = 404 nM	Bioorg. Med. Chem. Lett. 1997, 7, 21, 2747	RAR_alpha
ZINC13742307	agonist	Compound 4		EC50 = 33 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RAR_beta
ZINC13757372	agonist	Compound 11	Ki = 4 nM	EC50 = 9 nM	PMID: 8765503	RAR_beta
ZINC13758053	agonist	Compound 1	Kd = 2846 nM	EC50 = 1600 nM	PMID: 8784454	RAR_beta
ZINC13758055	agonist	Compound 2	Kd = 304 nM	EC50 = 280 nM	PMID: 8784454	RXR_alpha
ZINC13758062	agonist	Compound 4	Kd = 3993 nM	EC50 = 42 nM	PMID: 8784454	RXR_alpha
ZINC13758065	agonist	Compound 5	Kd = 73 nM	EC50 = 1900 nM	PMID: 8784454	RXR_alpha
ZINC13780871	agonist	Compound 10		relative EC30 = 3.3	PMID: 9703470	RAR_alpha
ZINC13780872	agonist	Compound 14a		relative EC30 = 0.081	PMID: 9703470	RXR_alpha
ZINC13780873	agonist	Compound 14c		relative EC30 = 0.30	PMID: 9703470	RXR_alpha
ZINC13780874	agonist	Compound 14d		relative EC30 = 32	PMID: 9703470	RXR_alpha
ZINC13794324	agonist	Compound 17	Ki = 209 nM	EC50 = 34 nM	PMID: 10052980	RXR_alpha
ZINC13794339	agonist	Compound 12	Ki = 80 nM	EC50 = 7 nM	PMID: 10052980	RXR_alpha
ZINC13794342	agonist	Compound 13	Ki = 323 nM	EC50 = 124 nM	PMID: 10052980	RXR_alpha
ZINC13911442	agonist	Compound 6a	Ki = 6 nM	EC50 = 24 nM	Bioorg. Med. Chem. Lett. 1997, 7, 21, 2747	RXR_alpha
ZINC26649488	agonist	Compound 6		EC50 = 4 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RAR_beta
ZINC26653564	agonist	Compound 8		EC50 = 86 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RXR_alpha
ZINC26653569	agonist	Compound 9		EC50 = 170 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RXR_alpha
ZINC26653776	agonist	Compound 5		EC50 = 2300 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RAR_alpha
ZINC26657237	agonist	Compound 7		EC50 = 160 nM	Bioorg. Med. Chem. Lett. 1995, 5, 22, 2729	RAR_alpha
ZINC26657257	agonist	Compound 11a	Ki = 172 nM	EC50 = 192 nM	Bioorg. Med. Chem. Lett. 1997, 7, 21, 2747	RXR_alpha
ZINC36241986	agonist	Compound 32	Ki = 299 nM	EC50 = 669 nM	PMID: 16364638	RXR_alpha
ZINC36241990	agonist	Compound 34	Ki = 131 nM	EC50 = 322 nM	PMID: 16364638	RXR_alpha
ZINC36241992	agonist	Compound 35	Ki = 35 nM	EC50 = 231 nM	PMID: 16364638	RXR_alpha
ZINC36241998	agonist	Compound 49	Ki = 100 nM	EC50 = 147 nM	PMID: 16364638	RXR_alpha
ZINC36242000	agonist	Compound 48	Ki = 202 nM	EC50 = 1263 nM	PMID: 16364638	RXR_beta
ZINC36242004	agonist	Compound 43	Ki = 162 nM	EC50 = 128 nM	PMID: 16364638	RXR_alpha
ZINC36242011	agonist	Compound 36	Ki = 38 nM	EC50 = 68 nM	PMID: 16364638	RXR_alpha
ZINC36766817	agonist	Compound 12	Kd = 16 nM	EC50 = 23 nM	PMID: 12482435	RXR_alpha
ZINC37865786	agonist	Compound 13	Kd = 22 nM	EC50 = 20 nM	PMID: 12482435	RXR_alpha
ZINC40896500	antagonist	Compound 5g		IC50 = 6.6 +/- 0.8 µM	PMID: 19095448	RXR_alpha
ZINC40896883	antagonist	Compound 5h		IC50 = 4.5 +/- 1.3 µM	PMID: 19095448	RXR_alpha
ZINC40933591	antagonist	Compound 5f		IC50 = 3.8 +/- 0.2 µM	PMID: 19095448	RXR_alpha
ZINC44418529	antagonist	Compound 5i		IC50 = 2.7 +/- 0.9 µM	PMID: 19095448	RXR_alpha
ZINC53159698	agonist	Compound 41	Ki = 150 nM	EC50 = 100 nM	PMID: 16364638	RXR_alpha
ZINC53255787	agonist	Compound 44	Ki = 99 nM	EC50 = 125 nM	PMID: 16364638	RXR_alpha
ZINC53267949	agonist	Compound 39	Ki = 31 nM	EC50 = 50 nM	PMID: 16364638	RXR_alpha
ZINC53268017	agonist	Compound 46	Ki = 211 nM	EC50 = 223 nM	PMID: 16364638	RXR_alpha
ZINC53268020	agonist	Compound 40	Ki = 121 nM	EC50 = 262 nM	PMID: 16364638	RXR_alpha
ZINC53268030	agonist	Compound 45	Ki = 110 nM	EC50 = 170 nM	PMID: 16364638	RXR_alpha
ZINC53268074	agonist	Compound 38	Ki = 221 nM	EC50 = 35 nM	PMID: 16364638
ZINC53268224	agonist	Compound 9	Ki = 10 nM	EC50 = 19 nM	PMID: 16364638	RXR_alpha
ZINC59480982	agonist	3-methyl-TTNPB	IC50 = 100 +/- 23 nM	EC50 = 1200 +/- 120 nM	PMID: 8308867	RAR_gamma