Compound ID Pharmacological profile Compound name Binding data Activity data Bibliographic ref Cross-reactivity
CHEMBL102720 agonist Compound 27 Ki = 1.2 +/- 0.2 nM EC50 = 14 +/- 8 nM PMID: 9464360  
CHEMBL102754 agonist Compound 26 Ki = 0.41 +/- 0.08 nM EC50 = 17 +/- 16 nM PMID: 9464360 MR
CHEMBL103092 agonist Compound 29 Ki = 1.8 +/- 0.8 nM EC50 = 16 +/- 10 nM PMID: 9464360  
CHEMBL103468 antagonist Compound 23 Ki = 13.3 +/- 1.2 nM IC50 = 105 +/- 40 nM PMID: 9464360  
CHEMBL104037 agonist Compound 12 Ki = 2.2 +/- 0.1 nM EC50 = 7.4 +/- 3.1 nM PMID: 9464361  
CHEMBL104183 agonist Compound 22 Ki = 0.48 +/- 0.18 nM EC50 = 3.6 +/- 0.7 nM PMID: 9464361  
CHEMBL104347 agonist Compound 27 Ki = 1.3 +/- 0.4 nM EC50 = 9.5 +/- 2.8 nM PMID: 9464361  
CHEMBL104451 agonist Compound 15 Ki = 2.7 +/- 0.5 nM EC50 = 270 +/- 70 nM PMID: 9464361  
CHEMBL106994 agonist Compound 8 Ki = 0.32 +/- 0.07 nM EC50 = 8.1 +/- 3.2 nM PMID: 9464361  
CHEMBL1076438 agonist Compound 4 IC50 = 57.3 +/- 5.0 nM EC50 = 1.1 +/- 0.4 nM PMID: 19863083  
CHEMBL1087512 agonist Compound 2   EC50 = 0.3 nM PMID: 19863083  
CHEMBL112058 antagonist Compound 23 Ki = 400 +/- 90 nM IC50 = 75 +/- 17 nM PMID: 9873735  
CHEMBL112987 agonist Compound 18 Ki = 0.87 +/- 0.13 nM EC50 = 6.8 +/- 0.8 nM PMID: 9873735  
CHEMBL113098 agonist Compound 26 Ki = 6.0 +/- 0.8 nM EC50 = 26 +/- 28 nM PMID: 9873735  
CHEMBL114435 antagonist Compound 25 Ki = 38.4 +/- 2.6 nM IC50 = 46 +/- 21 nM PMID: 9873735  
CHEMBL114553 antagonist Compound 27 Ki = 16.4 +/- 3.2 nM IC50 = 57 +/- 21 nM PMID: 9873735  
CHEMBL114611 agonist Compound 30 Ki = 24.3 +/- 4.3 nM EC50 = 187 +/- 43 nM PMID: 9873735  
CHEMBL114941 agonist Compound 20 Ki = 1.2 +/- 0.8 nM EC50 = 16 +/- 6 nM PMID: 9873735  
CHEMBL115173 antagonist Compound 9 Ki = 23 +/- 3 nM IC50 = 375 +/- 61 nM PMID: 9873735  
CHEMBL115903 antagonist Compound 19   IC50 = 267 nM PMID: 12419390  
CHEMBL116007 agonist Compound 14 Ki = 1.1 +/- 0.2 nM EC50 = 14 +/- 9 nM PMID: 9873735  
CHEMBL116221 agonist Compound 28 Ki = 1.5 +/- 0.5 nM EC50 = 14 +/- 9 nM PMID: 9873735  
CHEMBL1163480 antagonist Compound 48 Ki = 6.7 +/- 0.8 nM IC50 = 216 +/- 85 nM PMID: 20510622  
CHEMBL1163485 antagonist Compound 50 Ki = 8.5 +/- 0.9 nM IC50 = 193 +/- 43 nM PMID: 20510622  
CHEMBL1163585 antagonist Compound 26 Ki = 574 +/- 109 nM IC50 = 6064 +/- 2368 nM PMID: 20510622  
CHEMBL1163597 antagonist Compound 27 Ki = 23 +/- 4 nM IC50 = 3538 +/- 1048 nM PMID: 20510622  
CHEMBL1163598 antagonist Compound 22 Ki = 54 +/- 6 nM IC50 = 79 +/- 58 nM PMID: 20510622  
CHEMBL1163644 antagonist Compound 30 Ki = 68 +/- 14 nM IC50 = 805 nM PMID: 20510622  
CHEMBL1163898 antagonist Compound 41 Ki = 31 +/- 10 nM IC50 = 1831 +/- 811 nM PMID: 20510622  
CHEMBL1163899 antagonist Compound 42 Ki = 18 +/- 4 nM IC50 = 2696 +/- 873 nM PMID: 20510622  
CHEMBL1164752 antagonist Compound 47 Ki = 10.2 +/- 0.6 nM IC50 = 1555 +/- 197 nM PMID: 20510622  
CHEMBL1164857 antagonist Compound 44 Ki = 66 +/- 7 nM IC50 = 1213 +/- 688 nM PMID: 20510622  
CHEMBL1165483 antagonist Compound 46 Ki = 10.8 +/- 1.4 nM IC50 = 139 +/- 13 nM PMID: 20510622  
CHEMBL117322 antagonist Compound 7   IC50 = 102 nM PMID: 12419390  
CHEMBL117624 antagonist Compound 9   IC50 = 130 nM PMID: 12419390  
CHEMBL1208797 antagonist Compound 21   IC50 = 36 nM PMID: 20638844  
CHEMBL1209181 antagonist Compound 8   IC50 = 7 nM PMID: 20638844  
CHEMBL1209231 antagonist Compound 9   IC50 = 6 nM PMID: 20638844  
CHEMBL1209232 antagonist Compound 10   IC50 = 10 nM PMID: 20638844  
CHEMBL1209233 antagonist Compound 11   IC50 = 35 nM PMID: 20638844  
CHEMBL1209299 antagonist Compound 22   IC50 = 27 nM PMID: 20638844  
CHEMBL1209300 antagonist Compound 23   IC50 = 24 nM PMID: 20638844  
CHEMBL1209366 antagonist Compound 24   IC50 = 47 nM PMID: 20638844  
CHEMBL1209367 antagonist Compound 25   IC50 = 118 nM PMID: 20638844  
CHEMBL1215403 antagonist Compound 5g   IC50 = 0.9 \B5M PMID: 20672820 MR
CHEMBL1215406 antagonist Compound 5j   IC50 = 0.2 \B5M PMID: 20672820 MR
CHEMBL1215480 antagonist Compound 5l   IC50 = 0.3 \B5M PMID: 20672820 MR
CHEMBL132192 antagonist Compound 6i Ki = 433 +/- 93 nM IC50 = 52 +/- 15 nM PMID: 10743938  
CHEMBL134421 agonist Compound 6 Ki = 4.9 +/- 1.9 nM EC50 = 24.4 +/- 12.7 nM PMID: 9784110 MR
CHEMBL136464 agonist Compound 9 Ki = 3.5 +/- 2.2 nM EC50 = 59.5 +/- 33.2 nM PMID: 9784110  
CHEMBL137103 agonist Compound 22 Ki = 1.5 +/- 0.6 nM EC50 = 14.7 +/- 8.4 nM PMID: 9784110  
CHEMBL137902 agonist Compound 12 Ki = 8.7 +/- 2.5 nM EC50 = 31.5 +/- 15.7 nM PMID: 9784110  
CHEMBL139631 agonist Compound 19 Ki = 53.3 +/- 10.3 nM IC50 = 425 +/- 159 nM PMID: 9784110  
CHEMBL156142 antagonist Compound 9b   IC50 = 231 nM PMID: 9484511  
CHEMBL156278 antagonist Compound 19c   IC50 = 585 +/- 41 nM PMID: 9484511  
CHEMBL156751 antagonist Compound 29d   IC50 = 3162 nM PMID: 9484511  
CHEMBL156982 antagonist Compound 29c   IC50 = 274 +/- 122 nM PMID: 9484511  
CHEMBL157344 antagonist Compound 29f   IC50 = 362 nM PMID: 9484511  
CHEMBL157407 antagonist Compound 34   IC50 = 398 nM PMID: 9484511  
CHEMBL160230 antagonist Compound 21c   IC50 = 1105 nM PMID: 9484511  
CHEMBL160665 antagonist Compound 29a   IC50 = 348 nM PMID: 9484511  
CHEMBL160713 antagonist Compound 9h   IC50 = 1144 nM PMID: 9484511  
CHEMBL163425 antagonist Compound 17   IC50 = 150 nM PMID: 9871534  
CHEMBL164080 agonist Compound 6b IC50 = 12.0 nM EC50 = 3.50 nM PMID: 11859003  
CHEMBL164082 agonist Compound 4c IC50 = 41.3 nM EC50 = 2.9 nM PMID: 11859003  
CHEMBL164139 agonist Compound 6a IC50 = 11.5 nM EC50 = 0.35 nM PMID: 11859003  
CHEMBL164140 antagonist Compound 4k IC50 = 1682 nM IC50 = 51.2 nM PMID: 11859003  
CHEMBL164187 agonist Compound 5c IC50 = 2.9 nM EC50 = 2.40 nM PMID: 11859003  
CHEMBL164188 agonist Compound 5a IC50 = 27.0 nM EC50 = 1.05 nM PMID: 11859003  
CHEMBL164695 agonist Compound 4e IC50 = 7.3 nM EC50 = 0.35 nM PMID: 11859003  
CHEMBL164908 agonist Compound 4o IC50 = 212.5 nM EC50 = 32.0 nM PMID: 11859003  
CHEMBL165055 antagonist Compound 4m IC50 = 1793 nM IC50 = 158.8 nM PMID: 11859003  
CHEMBL165148 agonist Compound 4a IC50 = 23.0 nM EC50 = 2.60 nM PMID: 11859003  
CHEMBL165215 agonist Compound 4f IC50 = 24.7 nM EC50 = 8.20 nM PMID: 11859003  
CHEMBL165612 agonist Compound 4n IC50 = 166.0 nM EC50 = 23.0 nM PMID: 11859003  
CHEMBL165803 antagonist Compound 22   IC50 = 380 nM PMID: 9871534  
CHEMBL1672540 antagonist Compound 6 Ki = 478 +/- 287 nM IC50 = 3720 +/- 563 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
CHEMBL1672542 antagonist Compound 7a Ki = 454 +/- 188 nM IC50 = 765 +/- 171 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
 MR
CHEMBL167405 agonist Compound 5b IC50 = 8.1 nM EC50 = 0.20 nM PMID: 11859003  
CHEMBL167492 agonist Compound 6e IC50 = 113.4 nM EC50 = 4.55 nM PMID: 11859003  
CHEMBL167570 agonist Compound 4g IC50 = 7.1 nM EC50 = 1.7 nM PMID: 11859003  
CHEMBL167620 antagonist Compound 4l IC50 = 2060 nM IC50 = 92.6 nM PMID: 11859003  
CHEMBL167844 agonist Compound 6c IC50 = 4.9 nM EC50 = 0.8 nM PMID: 11859003  
CHEMBL167928 agonist Compound 4b IC50 = 9.0 nM EC50 = 2.40 nM PMID: 11859003  
CHEMBL1835810 antagonist Compound 11   IC50 = 0.51 \B5M PMID: 21916484  
CHEMBL190015 agonist Compound 15   EC50 = 0.1 nM PMID: 16078826  
CHEMBL190198 antagonist Compound 8 pKi = 7.4 pIC50 = 6.7 PMID: 15925510  
CHEMBL190900 antagonist Compound 10 pKi = 5.1 pIC50 = 6.4 PMID: 15925510  
CHEMBL191197 agonist Compound 17   EC50 = 0.1 nM PMID: 16078826  
CHEMBL191589 agonist Compound 16   EC50 = 0.5 nM PMID: 16078826  
CHEMBL193239 agonist Compound 18   EC50 = 0.35 nM PMID: 16078826  
CHEMBL1950696 antagonist Compound 6b   IC50 = 46 nM PMID: 22260770 GR
CHEMBL1950697 antagonist Compound 5d   IC50 = 85 nM PMID: 22260770 GR
CHEMBL1950698 antagonist Compound 6a   IC50 = 41 nM PMID: 22260770 GR
CHEMBL2112310 antagonist Compound 26   IC50 = 65 nM PMID: 10230628  
CHEMBL2112311 antagonist Compound 23   IC50 = 130 nM PMID: 10230628  
CHEMBL2112312 antagonist Compound 24   IC50 = 130 nM PMID: 10230628  
CHEMBL2113712 antagonist Compound 23 Ki = 243 +/- 39 nM IC50 = 260 +/- 62 nM PMID: 8627601  
CHEMBL24089 agonist Compound 8   EC50 = 1.6 nM PMID: 12657272  
CHEMBL241732 antagonist Compound 16   IC50 = 66.1 nM PMID: 17027272  
CHEMBL241733 antagonist Compound 17   IC50 = 71.8 nM PMID: 17027272  
CHEMBL24245 agonist Compound 32   EC50 = 1.25 nM PMID: 12657271  
CHEMBL24380 agonist Compound 5   EC50 = 1.7 nM PMID: 12657271  
CHEMBL24581 agonist Compound 19   EC50 = 26.5 nM PMID: 12657271  
CHEMBL24621 agonist Compound 3   EC50 = 1.0 nM PMID: 12657271  
CHEMBL24672 agonist Compound 4   EC50 = 49.8 nM PMID: 12657271  
CHEMBL24913 agonist Compound 33   EC50 = 300.0 nM PMID: 12657271  
CHEMBL24922 agonist Compound 40   EC50 = 2.5 nM PMID: 12657271  
CHEMBL24963 agonist Compound 47   EC50 = 80.1 nM PMID: 12657271  
CHEMBL24965 agonist Compound 7   EC50 = 1.1 nM PMID: 12657271  
CHEMBL25015 agonist Compound 6   EC50 = 2.5 nM PMID: 12657271  
CHEMBL25017 agonist Compound 17   EC50 = 2.5 nM PMID: 12657271  
CHEMBL25021 agonist Compound 20   EC50 = 1.6 nM PMID: 12657272  
CHEMBL25036 agonist Compound 20   EC50 = 44.9 nM PMID: 12657271  
CHEMBL25037 agonist Compound 18   EC50 = 79.5 nM PMID: 12657271  
CHEMBL25061 agonist Compound 10   EC50 = 5.3 nM PMID: 12657272  
CHEMBL25181 agonist Compound 11   EC50 = 11.4 nM PMID: 12657271  
CHEMBL25261 agonist Compound 14   EC50 = 28.7 nM PMID: 12657272  
CHEMBL25415 agonist Compound 35   EC50 = 5.7 nM PMID: 12657271  
CHEMBL25430 agonist Compound 13   EC50 = 200 nM PMID: 12657272  
CHEMBL25462 agonist Compound 13   EC50 = 0.9 nM PMID: 12657271  
CHEMBL25463 agonist Compound 34   EC50 = 0.3 nM PMID: 12657271  
CHEMBL25469 agonist Compound 31   EC50 = 0.7 nM PMID: 12657271  
CHEMBL25556 agonist Compound 28   EC50 = 5.7 nM PMID: 12657271  
CHEMBL25682 agonist Compound 22   EC50 = 200.0 nM PMID: 12657271  
CHEMBL267270 antagonist Compound 21   IC50 = 270 nM PMID: 10230628  
CHEMBL26770 agonist Compound 31   EC50 = 14.8 nM PMID: 12657272  
CHEMBL26997 agonist Compound 24   EC50 = 4.3 nM PMID: 12657272  
CHEMBL27052 agonist Compound 38   EC50 = 23.5 nM PMID: 12657272  
CHEMBL270976 agonist Compound 22   EC50 = 2.0 nM PMID: 12657272  
CHEMBL27379 agonist Compound 25   EC50 = 0.5 nM PMID: 12657272  
CHEMBL277422 agonist Compound 37   EC50 = 7.2 nM PMID: 12657271  
CHEMBL27766 agonist Compound 40   EC50 = 1.9 nM PMID: 12657272  
CHEMBL27818 agonist Compound 39   EC50 = 1.4 nM PMID: 12657272  
CHEMBL279464 agonist Compound 39   EC50 = 4.7 nM PMID: 12657271  
CHEMBL280121 agonist Compound 36   EC50 = 88.5 nM PMID: 12657271  
CHEMBL28031 agonist Compound 36   EC50 = 0.5 nM PMID: 12657272  
CHEMBL280613 agonist Compound 8   EC50 = 0.4 nM PMID: 12657271  
CHEMBL280767 agonist Compound 34   EC50 = 1.9 nM PMID: 12657272  
CHEMBL280805 agonist Compound 12   EC50 = 5 nM PMID: 12657272  
CHEMBL280956 agonist Compound 14   EC50 = 1.7 nM PMID: 12657271  
CHEMBL28102 agonist Compound 30   EC50 = 1.4 nM PMID: 12657272  
CHEMBL281182 agonist Compound 12   EC50 = 1.5 nM PMID: 12657271  
CHEMBL28157 agonist Compound 29   EC50 = 0.36 nM PMID: 12657272  
CHEMBL28161 agonist Compound 27   EC50 = 0.8 nM PMID: 12657272  
CHEMBL28199 agonist Compound 10   EC50 = 1.5 nM PMID: 12657271  
CHEMBL282091 agonist Compound 15   EC50 = 0.6 nM PMID: 12657271  
CHEMBL28213 agonist Compound 37   EC50 = 7.7 nM PMID: 12657272  
CHEMBL28255 agonist Compound 9   EC50 = 7.2 nM PMID: 12657271  
CHEMBL282649 agonist Compound 30   EC50 = 1.2 nM PMID: 12657271  
CHEMBL282650 agonist Compound 29   EC50 = 0.4 nM PMID: 12657271  
CHEMBL282774 agonist Compound 28   EC50 = 4.2 nM PMID: 12657272  
CHEMBL283759 agonist Compound 15   EC50 = 9.8 nM PMID: 12657272  
CHEMBL285139 agonist Compound 33   EC50 = 0.3 nM PMID: 12657272  
CHEMBL285872 agonist Compound 2   EC50 = 11.6 nM PMID: 12657271  
CHEMBL286029 agonist Compound 32   EC50 = 2.6 nM PMID: 12657272  
CHEMBL286446 agonist Compound 17 Ki = 0.44 +/- 0.03 nM EC50 = 3.2 +/- 0.9 nM PMID: 9873735  
CHEMBL286662 agonist Compound 10 Ki = 24.6 +/- 1.1 nM IC50 = 376 +/- 201 nM PMID: 10212133  
CHEMBL287428 agonist Compound 26   EC50 = 5.4 nM PMID: 12657272  
CHEMBL293409 antagonist Compound 12a Ki = 144 +/- 56 nM IC50 = 104 nM PMID: 12781198  
CHEMBL299512 antagonist Compound 21 Ki = 28.8 +/- 0.8 nM IC50 = 1800 +/- 0 nM PMID: 8627601  
CHEMBL299828 antagonist Compound 16 Ki = 109 +/- 14 nM IC50 = 580 nM PMID: 8627601  
CHEMBL302362 agonist Compound 16 Ki = 0.66 +/- 0.20 nM EC50 = 5.7 +/- 3.7 nM PMID: 9784110  
CHEMBL315445 antagonist Compound 17b Ki = 332.0 nM IC50 = 83.8 nM PMID: 11591515  
CHEMBL316078 antagonist Compound 15a Ki = 150.0 nM IC50 = 17.0 nM PMID: 11591515  
CHEMBL316348 antagonist Compound 16m Ki = 25.5 +/- 4.1 nM IC50 = 80 +/- 17 nM PMID: 9873612  
CHEMBL318409 agonist Compound 19 Ki = 0.74 +/- 0.08 nM EC50 = 6.9 +/- 1.8 nM PMID: 9464361  
CHEMBL318513 agonist Compound 24 Ki = 2.6 +/- 0.2 nM EC50 = 13 +/- 2 nM PMID: 9464360 MR
CHEMBL319915 agonist Compound 23 Ki = 0.55 nM EC50 = 7.1 +/- 1.3 nM PMID: 9464361  
CHEMBL320164 agonist Compound 16 Ki = 0.37 +/- 0.10 nM EC50 = 5.0 +/- 2.0 nM PMID: 9464361  
CHEMBL320411 antagonist Compound 21 Ki = 8.8 +/- 1.2 nM IC50 = 132 +/- 95 nM PMID: 9464360  
CHEMBL320632 agonist Compound 18 Ki = 1.3 +/- 0.2 nM EC50 = 15 +/- 7.2 nM PMID: 9464361  
CHEMBL322108 agonist Compound 21 Ki = 3.5 +/- 0.3 nM EC50 = 9.3 +/- 4.0 nM PMID: 9873735  
CHEMBL322312 agonist Compound 21 Ki = 0.93 +/- 0.27 nM EC50 = 13 +/- 5.4 nM PMID: 9464361  
CHEMBL322485 agonist Compound 25 Ki = 0.34 nM EC50 = 3.7 +/- 0.5 nM PMID: 9464361  
CHEMBL322575 agonist Compound 10 Ki = 0.59 +/- 0.16 nM EC50 = 9.0 +/- 1.2 nM PMID: 9464361  
CHEMBL322576 agonist Compound 20 Ki = 0.59 +/- 0.13 nM EC50 = 5.2 +/- 1.0 nM PMID: 9464361  
CHEMBL324156 antagonist Compound 8   IC50 = 185 nM PMID: 12419390  
CHEMBL32603 agonist Compound 29 Ki = 4.9 +/- 1.3 nM EC50 = 17 +/- 6 nM PMID: 10212133  
CHEMBL326092 agonist Compound 15 Ki = 2.9 +/- 0.3 nM EC50 = 15 +/- 2 nM PMID: 9873735  
CHEMBL327409 antagonist Compound 9f Ki = 714.0 nM IC50 = 62.0 nM PMID: 11591515  
CHEMBL327934 antagonist Compound 17m Ki = 62.5 +/- 7.1 nM IC50 = 46 +/- 22 nM PMID: 9873612  
CHEMBL32812 agonist Compound 8 Ki = 0.83 +/- 0.04 nM EC50 = 7.6 +/- 3.7 nM PMID: 9784110  
CHEMBL328261 antagonist Compound 16i Ki = 449 +/- 61 nM IC50 = 99 +/- 27 nM PMID: 9873612  
CHEMBL328787 antagonist Compound 16p Ki = 202 +/- 31 nM IC50 = 74 +/- 23 nM PMID: 9873612  
CHEMBL329631 antagonist Compound 9d Ki = 525.0 nM IC50 = 73.1 nM PMID: 11591515  
CHEMBL330702 antagonist Compound 16n Ki = 53.1 +/- 8 nM IC50 = 163 +/- 44 nM PMID: 9873612  
CHEMBL333167 antagonist Compound 29 Ki = 80.5 +/- 0.5 nM IC50 = 49 +/- 14 nM PMID: 9873735  
CHEMBL334747 agonist Compound 7k Ki = 11.4 +/- 4.3 nM EC50 = 97 nM PMID: 12954062  
CHEMBL335591 agonist Compound 10 Ki = 5.5 +/- 2.3 nM EC50 = 57.8 +/- 22.5 nM PMID: 9784110  
CHEMBL336169 agonist Compound 18c Ki = 4.7 +/- 1.5 nM EC50 = 21 nM PMID: 12954062  
CHEMBL337262 agonist Compound 14 Ki = 18.7 +/- 4.1 nM EC50 = 117 +/- 89 nM PMID: 9784110  
CHEMBL342190 agonist Compound 25 Ki = 12.6 +/- 2.6 nM EC50 = 47.7 +/- 29.1 nM PMID: 9784110  
CHEMBL342426 agonist Compound 24 Ki = 3.6 +/- 1.1 nM EC50 = 14.7 +/- 6.0 nM PMID: 9784110  
CHEMBL344627 agonist Compound 13 Ki = 1.3 +/- 0.6 nM EC50 = 57.8 +/- 22.5 nM PMID: 9784110  
CHEMBL347910 antagonist Compound 9d   IC50 = 3726 +/- 371 nM PMID: 9484511  
CHEMBL34824 agonist Compound 28 Ki = 3.5 +/- 1.7 nM EC50 = 8.7 +/- 5.5 nM PMID: 10212133  
CHEMBL34882 agonist Compound 26 Ki = 6.3 +/- 0.1 nM EC50 = 47 +/- 13 nM PMID: 10212133  
CHEMBL349398 antagonist Compound 4j IC50 = 3042 nM IC50 = 126.6 nM PMID: 11859003  
CHEMBL350465 antagonist Compound 29b   IC50 = 2334 nM PMID: 9484511  
CHEMBL351148 antagonist Compound 9f   IC50 = 543 +/- 215 nM PMID: 9484511  
CHEMBL351751 agonist Compound 6h IC50 = 7.9 nM EC50 = 0.9 nM PMID: 11859003  
CHEMBL352002 antagonist Compound 19e   IC50 = 2931 nM PMID: 9484511  
CHEMBL398801 antagonist Compound 15   IC50 = 32.2 nM PMID: 17027272  
CHEMBL409 antagonist bicalutamide   IC50 = 1819 +/- 245 nM PMID: 9484511  
CHEMBL410683 antagonist Z-guggulsterone Ki = 224 +/- 6 nM IC50 = 740 +/- 220 nM PMID: 16250653
FXR_alpha
CHEMBL412874 agonist Compound 23   EC50 = 71.4 nM PMID: 12657272  
CHEMBL415289 antagonist Compound 18   IC50 = 280 nM PMID: 10230628  
CHEMBL416411 agonist Compound 13 Ki = 0.32 +/- 0.11 nM EC50 = 2.8 +/- 0.7 nM PMID: 9464361  
CHEMBL417475 agonist Compound 35   EC50 = 1.0 nM PMID: 12657272  
CHEMBL418990 agonist Compound 17 Ki = 0.78 +/- 0.33 nM EC50 = 10 +/- 2.9 nM PMID: 9464361  
CHEMBL422268 agonist Compound 7l Ki = 2.6 +/- 0.9 nM EC50 = 48 nM PMID: 12954062  
CHEMBL422707 antagonist Compound 19g   IC50 = 3277 nM PMID: 9484511  
CHEMBL428513 agonist Compound 16   EC50 = 2.6 nM PMID: 12657271  
CHEMBL429056 agonist Compound 21   EC50 = 42.0 nM PMID: 12657271  
CHEMBL431807 agonist Compound 24 Ki = 1.1 nM EC50 = 7.4 +/- 3.0 nM PMID: 9464361  
CHEMBL435822 agonist Compound 7 Ki = 5.6 +/- 2.6 nM EC50 = 29.0 +/- 11.3 nM PMID: 9784110  
CHEMBL446389 agonist Compound 4   EC50 = 245.8 nM PMID: 18722119  
CHEMBL482625 antagonist Compound 23   IC50 = 119.8 nM PMID: 18722119  
CHEMBL48358 antagonist Compound 8b Ki = 156 +/- 4 nM IC50 = 783 +/- 83 nM PMID: 8627601  
CHEMBL486707 antagonist Compound 10o   IC50 = 349.4 nM PMID: 18504132  
CHEMBL486915 antagonist Compound 10ac   IC50 = 29.9 nM PMID: 18504132  
CHEMBL486916 antagonist Compound 10ad   IC50 = 107.6 nM PMID: 18504132  
CHEMBL48745 antagonist Compound 8d Ki = 441 +/- 58 nM IC50 = 1200 nM PMID: 8627601  
CHEMBL487930 antagonist Compound 10l   IC50 = 65.5 nM PMID: 18504132  
CHEMBL488351 antagonist Compound 10p   IC50 = 365.7 nM PMID: 18504132  
CHEMBL488556 antagonist Compound 10r   IC50 = 116.7 nM PMID: 18504132  
CHEMBL488559 antagonist Compound 20a   IC50 = 82.4 nM PMID: 18504132  
CHEMBL488560 antagonist Compound 11b   IC50 = 78.2 nM PMID: 18504132  
CHEMBL489788 agonist Compound 13   EC50 = 0.4 nM PMID: 18722119
GR
CHEMBL489991 antagonist Compound 15   IC50 = 56.6 nM PMID: 18722119  
CHEMBL491205 agonist Compound 5   EC50 = 137.7 nM PMID: 18722119  
CHEMBL492021 agonist Compound 10 IC50 = 2.4 nM EC50 = 0.8 nM PMID: 18722119  
CHEMBL49754 antagonist Compound 22b Ki = 119 +/- 21 nM IC50 = 1350 +/- 71 nM PMID: 8627601  
CHEMBL50023 antagonist Compound 22a Ki = 53.5 +/- 1.2 nM IC50 = 1050 +/- 235 nM PMID: 8627601  
CHEMBL501080 antagonist Compound 10u   IC50 = 11.8 nM PMID: 18504132  
CHEMBL506297 antagonist Compound 10s   IC50 = 59.2 nM PMID: 18504132  
CHEMBL50786 antagonist Compound 24 Ki = 88 +/- 7 nM IC50 = 1950 +/- 1200 nM PMID: 8627601  
CHEMBL519394 antagonist Compound 10n   IC50 = 100.0 nM PMID: 18504132  
CHEMBL520127 agonist Compound 22   EC50 = 37.5 nM PMID: 18722119  
CHEMBL520223 antagonist Compound 10t   IC50 = 62.5 nM PMID: 18504132  
CHEMBL520534 antagonist Compound 10m   IC50 = 207.7 nM PMID: 18504132  
CHEMBL522432 agonist Compound 12 IC50 = 3.4 nM EC50 = 0.8 nM PMID: 18722119
GR
CHEMBL523659 agonist Compound 9 IC50 = 3.8 nM EC50 = 0.7 nM PMID: 18722119  
CHEMBL523825 antagonist Compound 16   IC50 = 36.5 nM PMID: 18722119  
CHEMBL530107 antagonist Compound 10q   IC50 = 138.3 nM PMID: 18504132  
CHEMBL530109 antagonist Compound 20b   IC50 = 34.1 nM PMID: 18504132  
CHEMBL549554 agonist Compound 32 IC50 = 63 nM EC50 = 4.5 nM PMID: 19376703  
CHEMBL552108 agonist Compound 31 IC50 = 40 nM EC50 = 3.0 nM PMID: 19376703  
CHEMBL552156 agonist Compound 27 IC50 = 32 nM EC50 = 4.7 nM PMID: 19376703  
CHEMBL555562 agonist Compound 33 IC50 = 50 nM EC50 = 4.0 nM PMID: 19376703  
CHEMBL556891 agonist Compound 9 IC50 = 13 nM EC50 = 0.02 nM PMID: 19376703  
CHEMBL556892 agonist Compound 14 IC50 = 13 nM EC50 = 0.04 nM PMID: 19376703  
CHEMBL557293 agonist Compound 25 IC50 = 16 nM EC50 = 0.02 nM PMID: 19376703  
CHEMBL559580 agonist Compound 7 IC50 = 20 nM EC50 = 060 nM PMID: 19376703  
CHEMBL559581 agonist Compound 8 IC50 = 32 nM EC50 = 14 nM PMID: 19376703  
CHEMBL559974 agonist Compound 10 IC50 = 13 nM EC50 = 0.5 nM PMID: 19376703  
CHEMBL562509 agonist Compound 26 IC50 = 13 nM EC50 = 0.05 nM PMID: 19376703  
CHEMBL563070 agonist Compound 34 IC50 = 398 nM EC50 = 1665 nM PMID: 19376703  
CHEMBL563716 agonist Compound 16 IC50 = 16 nM EC50 = 0.6 nM PMID: 19376703  
CHEMBL564015 agonist Compound 17 IC50 = 32 nM EC50 = 35 nM PMID: 19376703  
CHEMBL564782 agonist Compound 4 IC50 = 25 nM EC50 = 6.0 nM PMID: 19376703  
CHEMBL566125 antagonist Compound 16   IC50 = 65 nM PMID: 19864132  
CHEMBL567438 antagonist Compound 12   IC50 = 3 nM PMID: 19864132  
CHEMBL568048 antagonist Compound 18   IC50 = 18 nM PMID: 19864132  
CHEMBL568062 agonist Compound 10   EC50 = 1 nM PMID: 19864132  
CHEMBL568081 agonist Compound 9   EC50 = 19 nM PMID: 19864132  
CHEMBL570708 agonist Compound 11 pIC50 = 7.3 pEC50 = 8.6 PMID: 19664922  
CHEMBL578556 antagonist Compound 17   IC50 = 10 nM PMID: 19864132  
CHEMBL585188 agonist Compound 11   EC50 = 2 nM PMID: 19864132  
CHEMBL62700 agonist Compound 7 Ki = 2.1 +/- 0.3 nM EC50 = 2.2 +/- 0.9 nM PMID: 12781197  
CHEMBL62981 agonist Compound 15 Ki = 8.0 +/- 2.9 nM EC50 = 11 +/- 1 nM PMID: 12781197 GR
CHEMBL63788 antagonist Compound 12b Ki = 45 +/- 7 nM IC50 = 217 nM PMID: 12781198  
CHEMBL6441 antagonist Compound 5b   IC50 = 100 nM PMID: 10230628  
CHEMBL64913 agonist Compound 6 Ki = 6.1 +/- 2.6 nM EC50 = 1000 +/- 300 nM PMID: 12781197  
CHEMBL65014 agonist Compound 13 Ki = 3.1 nM EC50 = 28 +/- 12 nM PMID: 12781197  
CHEMBL65054 antagonist Compound 12d Ki = 391 nM IC50 = 499 nM PMID: 12781198  
CHEMBL65380 antagonist Compound 12c Ki = 370 nM IC50 = 483 nM PMID: 12781198  
CHEMBL65410 agonist Compound 12 Ki = 26 nM EC50 = 29 +/- 12 nM PMID: 12781197  
CHEMBL65690 agonist Compound 10 Ki = 2.5 +/- 0.4 nM EC50 = 1.7 +/- 0.6 nM PMID: 12781197 GR
CHEMBL65929 agonist Compound 18 Ki = 6.3 +/- 5.7 nM EC50 = 2.1 +/- 1.0 nM PMID: 12781197
GR
CHEMBL6654 antagonist Compound 31   IC50 = 440 nM PMID: 10230628  
CHEMBL67914 antagonist Compound 34   IC50 = 180 nM PMID: 15081005  
CHEMBL6843 antagonist Compound 19   IC50 = 200 nM PMID: 10230628  
CHEMBL6855 antagonist Compound 20   IC50 = 106 nM PMID: 10230628  
CHEMBL7289 antagonist Compound 10   IC50 = 570 nM PMID: 10230628  
CHEMBL90766 antagonist Compound 8i Ki = 29.1 +/- 4.8 nM IC50 = 158 +/- 67 nM PMID: 9873612  
CHEMBL91708 antagonist Compound 16e Ki = 1858 +/- 208 nM IC50 = 3443 +/- 547 nM PMID: 9873612  
CHEMBL92026 antagonist Compound 9e Ki = 521.0 nM IC50 = 112.8 nM PMID: 11591515  
CHEMBL93407 antagonist Compound 16a Ki = 483 +/- 32 nM IC50 = 609 nM PMID: 9873612  
CHEMBL93451 antagonist Compound 16g Ki = 101 +/- 21 nM IC50 = 122 +/- 10 nM PMID: 9873612  
CHEMBL93894 antagonist Compound 15a Ki = 87 +/- 11 nM IC50 = 424 +/- 74 nM PMID: 9873612  
CHEMBL93906 antagonist Compound 15b Ki = 30.0 nM IC50 = 10.0 nM PMID: 11591515  
CHEMBL94053 antagonist Compound 17a Ki = 127.0 nM IC50 = 460.7 nM PMID: 11591515  
CHEMBL94286 antagonist Compound 8a Ki = 3553 +/- 420 nM IC50 = 353 nM PMID: 9873612  
CHEMBL94749 agonist Compound 14 Ki = 0.49 +/- 0.16 nM EC50 = 2.7 +/- 0.2 nM PMID: 9464361  
CHEMBL94753 agonist Compound 26 Ki = 0.50 nM EC50 = 9.4 +/- 2.6 nM PMID: 9464361  
ZINC00007444 agonist Compound 10 Ki = 19 +/- 3 nM IC50 = 38 +/- 6 nM PMID: 9719599  
ZINC00008882 agonist Compound 35   EC50 = 2.1 nM PMID: 15081005  
ZINC00008885 antagonist Compound 4a   IC50 = 3.8 nM PMID: 12238914  
ZINC00017348 agonist Compound 11 Ki = 10 +/- 1 nM IC50 = 30 +/- 4 nM PMID: 9719599  
ZINC00026396 antagonist Compound 32 IC50 = 230 nM IC50 = 13.6 nM PMID: 12419390  
ZINC00026398 antagonist Compound 36   IC50 = 36 nM PMID: 15081005  
ZINC00026401 antagonist Compound 10 IC50 = 25 nM IC50 = 15 nM PMID: 18318463  
ZINC00026404 agonist Compound 6   EC50 = 2.0 nM PMID: 18318463  
ZINC01482051 agonist dydrogesterone     PMID: 14670641  
ZINC01549657 agonist Compound 4d IC50 = 10.0 nM EC50 = 32.0 nM PMID: 11859003  
ZINC01682604 antagonist Compound 11   IC50 = 84 \B5M PMID: 18586498  
ZINC01849618 agonist levonorgestrel     PMID: 14670641  
ZINC02913210 antagonist Compound 25   IC50 = 8.1 \B5M PMID: 18586498  
ZINC03200253 antagonist Compound 20   IC50 = 4.1 \B5M PMID: 18586498  
ZINC03201981 agonist norethisterone Ki = 1.87 +/- 0.13 nM EC50 = 2.2 +/- 1.3 nM PMID: 9464361  
ZINC03213078 antagonist Compound 16   IC50 = 20 \B5M PMID: 18586498  
ZINC03814363 agonist cyproterone acetate     PMID: 14670641 GR
ZINC03814376 antagonist Compound 16   IC50 = 170 nM PMID: 9871534
AR
ZINC03814382 antagonist mifepristone Ki = 15 +/- 2.6 nM Kif = 11.8 +/- 3.5 nM PMID: 12036351
AR
ZINC03814394 agonist gestodene     PMID: 14670641 AR
ZINC03814399 antagonist Compound 21b   IC50 = 2200 nM PMID: 9484511 AR
ZINC03814407 antagonist Compound 9e   IC50 = 330 nM PMID: 9484511 AR
ZINC03814408 agonist promegestone Kd = 0.4 nM   PMID: 20355713  
ZINC03814420 agonist metribolone     PMID: 561151 AR
ZINC03818363 agonist Compound 9d   EC50 = 2.87 nM PMID: 18226526  
ZINC03818364 agonist Compound 11   EC50 = 1.3 nM PMID: 18226526  
ZINC03818371 agonist Compound 9e   EC50 = 9.8 nM PMID: 18226526  
ZINC03831939 agonist Compound 19 0.74 +/- 0.08 EC50 = 6.90+/- 1.8 PMID: 9464361  
ZINC03831947 antagonist onapristone     PMID: 7626494 GR
ZINC03831981 agonist Compound 18 Ki = 1.3 +/- 0.1 nM EC50 = 4.5 +/- 1.3 nM PMID: 10212133  
ZINC03831989 agonist Compound 22 Ki = 2.6 +/- 0.2 nM EC50 = 6.3 +/- 3.1 nM PMID: 10212133  
ZINC03831991 agonist Compound 17 Ki = 21.3 +/- 3.7 nM EC50 = 5.3 +/- 2.1 nM PMID: 10212133  
ZINC03832311 agonist Compound 6g Ki = 2.6 +/- 1.0 nM EC50 = 31 +/- 20 nM PMID: 10743938  
ZINC03832314 antagonist Compound 6d Ki = 12 +/- 3 nM IC50 = 43 +/- 18 nM PMID: 10743938  
ZINC03832315 antagonist Compound 6b Ki = 25 +/- 5 nM IC50 = 232 +/- 48 nM PMID: 10743938  
ZINC03832316 antagonist Compound 6k Ki = 26 +/- 2 nM IC50 = 33 +/- 13 nM PMID: 10743938
GR
ZINC03832317 antagonist Compound 5d Ki = 31 +/- 10 nM IC50 = 109 +/- 32 nM PMID: 10743938  
ZINC03832318 antagonist Compound 6e Ki = 31 +/- 7 nM IC50 = 65 +/- 31 nM PMID: 10743938  
ZINC03832320 antagonist Compound 5e Ki = 36 +/- 5 nM IC50 = 124 +/- 31 nM PMID: 10743938  
ZINC03832321 antagonist Compound 5b Ki = 37 +/- 16 nM IC50 = 245 +/- 22 nM PMID: 10743938  
ZINC03832323 antagonist Compound 6f Ki = 80 +/- 8 nM IC50 = 729 +/- 204 nM PMID: 10743938  
ZINC03832325 antagonist Compound 6a Ki = 237 +/- 80 nM IC50 = 416 +/- 98 nM PMID: 10743938  
ZINC03832326 antagonist Compound 6j Ki = 249 +/- 58 nM IC50 = 242 +/- 80 nM PMID: 10743938  
ZINC03833830 antagonist Compound 31 Ki = 455 +/- 38 nM IC50 = 660 nM PMID: 8627601  
ZINC03833831 antagonist Compound 34a Ki = 71 +/- 9 nM IC50 = 1050 +/- 495 nM PMID: 8627601  
ZINC03833833 antagonist Compound 1 Ki = 490 +/- 30 nM IC50 = 549 +/- 55 nM PMID: 8627601  
ZINC03833837 agonist Compound 2 Ki = 343 +/- 23 nM EC50 = 35 +/- 2 nM PMID: 8627601  
ZINC03920458 antagonist zk112993     PMID: 8033109  
ZINC03920657 antagonist Compound 2   IC50 = 0.2 nM PMID: 18243712  
ZINC03927200 agonist drospirenone     PMID: 8922878\A0 MR
ZINC03930677 antagonist org33628     PMID: 7625721  
ZINC03936191 antagonist asoprinil   IC50 = 0.3 nM PMID: 23079530 AR
ZINC03938677 agonist mometasone furoate   Kd = 0.08 nM PMID: 15189034  
ZINC03944167 agonist RWJ26819\A0 Kd = 0.12 nM IC50 = 8 nM PMID: 11179906  
ZINC03945835 antagonist Compound 18h   IC50 = 520 +/- 190 nM PMID: 17703938 AR
ZINC03994231 antagonist ZK230211 RBA = 140% IC50 = 0.0036 nM PMID:\A0 11150172  
ZINC03994337 antagonist Compound 30   IC50 = 20.6 nM PMID: 12419390  
ZINC03994338 agonist Compound 37   EC50 = 60 nM PMID: 15081005  
ZINC04081723 agonist medroxyprogesterone     PMID: 14670641  
ZINC04097440 agonist mometasone IC50 = 1.9 nM EC50 = 0.028 +/- 0.017 PMID: 17697148  
ZINC04215629 agonist dienogest     PMID: 14670641  
ZINC04217604 agonist trimegestone     PMID: 11108870  
ZINC04428529 agonist progesterone Ki = 3.5 +/- 0.2 nM EC50 = 2.9 +/- 0.9 nM PMID: 9784110
GR
ZINC04655055 antagonist hydroxyflutamide   IC50 = 2013 +/- 194 nM PMID: 9484511 AR
ZINC05137928 antagonist Compound 2   IC50 = 0.17 nM PMID: 19216549  
ZINC05315096 agonist Compound 3 Ki = 133 +/- 71 nM IC50 = 783 +/- 162 nM PMID: 9719599  
ZINC05373275 agonist Atractylrnolide III   RLA = 3.39 (at 100\B5M) PMID: 22365756  
ZINC05426273 antagonist Compound 22   IC50 = 1.3 \B5M PMID: 18586498  
ZINC05482359 antagonist Compound 24   IC50 = 11 \B5M PMID: 18586498  
ZINC05500168 antagonist Compound 17   IC50 = 13 \B5M PMID: 18586498  
ZINC06245719 agonist tanaproget IC50 = 0.5 nM EC50 = 0.15 nM PMID: 18318463  
ZINC06661388 antagonist Compound 12   IC50 = 30 \B5M PMID: 18586498  
ZINC06670445 antagonist Compound 13   IC50 = 23 \B5M PMID: 18586498  
ZINC09926727 antagonist Compound 14   IC50 = 11 \B5M PMID: 18586498  
ZINC12349471 antagonist Compound 5   IC50 = 109 +/- 24 nM PMID: 9484511  
ZINC12349477 antagonist Compound 4l   IC50 = 6.7 nM PMID: 12238914 MR
ZINC12349504 antagonist Compound 9i   IC50 = 1828 nM PMID: 9484511  
ZINC13439601 agonist Compound 4h IC50 = 42.0 nM EC50 = 10.9 nM PMID: 11859003  
ZINC13439677 antagonist Compound 7 IC50 = 301.0 nM IC50 = 103.0 nM PMID: 11859003  
ZINC13488887 antagonist Compound 18   IC50 = 56 nM PMID: 12419390  
ZINC13488899 agonist Compound 21   EC50 = 2.5 nM PMID: 12657272  
ZINC13490439 agonist Compound 11c Ki = 12.9 +/- 1.2 nM EC50 = 171 nM PMID: 12781198  
ZINC13490442 antagonist Compound 11f Ki = 273 nM IC50 = 782 nM PMID: 12781198  
ZINC13490452 antagonist Compound 11p Ki = 12.4 +/- 1.3 nM IC50 = 461 nM PMID: 12781198 GR
ZINC13491402 antagonist Compound 4b   IC50 = 500.0 nM PMID: 12238914  
ZINC13491403 antagonist Compound 4c   IC50 = 9.3 nM PMID: 12238914  
ZINC13491404 antagonist Compound 4d   IC50 = 642.0 nM PMID: 12238914  
ZINC13491405 antagonist Compound 4e   IC50 = 9.9 nM PMID: 12238914  
ZINC13491406 antagonist Compound 4f   IC50 = 38.3 nM PMID: 12238914  
ZINC13491407 antagonist Compound 4g   IC50 = 2.6 nM PMID: 12238914 MR
ZINC13491408 antagonist Compound 4h   IC50 = 15.9 nM PMID: 12238914 MR
ZINC13491409 antagonist Compound 4i   IC50 = 55.0 nM PMID: 12238914  
ZINC13491410 antagonist Compound 4j   IC50 = 37.0 nM PMID: 12238914 MR
ZINC13491411 antagonist Compound 4k   IC50 = 98.8 nM PMID: 12238914  
ZINC13491412 antagonist Compound 4m   IC50 = 40.2 nM PMID: 12238914  
ZINC13652885 agonist Compound 12   EC50 = 0.15 nM PMID: 16078826  
ZINC13652886 agonist Compound 14   EC50 = 21.1 nM PMID: 16078826  
ZINC13755705 antagonist Compound 27a Ki = 218 +/- 23 nM IC50 = 741 +/- 98 nM PMID: 8627601  
ZINC13755709 agonist Compound 9 Ki = 22 +/- 3 nM EC50 = 458 nM PMID: 8627601  
ZINC13755725 antagonist Compound 30 Ki = 275 +/- 21 nM IC50 = 2000 nM PMID: 8627601  
ZINC13777077 antagonist Compound 1 Ki = 669 +/- 71 nM IC50 = 305 nM PMID: 9464360  
ZINC13777078 antagonist Compound 4 Ki = 119 +/- 24 nM IC50 = 194 +/- 23 nM PMID: 9464360  
ZINC13777079 antagonist Compound 5 Ki = 274 +/- 121 nM IC50 = 170 +/- 51 nM PMID: 9464360  
ZINC13778327 antagonist Compound 9a   IC50 = 49 +/- 11 nM PMID: 9484511  
ZINC13778333 antagonist Compound 9c   IC50 = 3346 +/- 879 nM PMID: 9484511  
ZINC13778346 antagonist Compound 9g   IC50 = 2708 +/- 81 nM PMID: 9484511  
ZINC13778356 antagonist Compound 19a   IC50 = 233 +/- 69 nM PMID: 9484511 AR
ZINC13778363 antagonist Compound 19d   IC50 = 4395 nM PMID: 9484511  
ZINC13778367 antagonist Compound 19f   IC50 = 1239 nM PMID: 9484511  
ZINC13778373 antagonist Compound 21a   IC50 = 136 +/- 88 nM PMID: 9484511  
ZINC13778392 antagonist Compound 29e   IC50 = 876 +/- 68 nM PMID: 9484511  
ZINC13778399 antagonist Compound 36   IC50 = 390 +/- 138 nM PMID: 9484511 AR
ZINC13778400 antagonist Compound 42   IC50 = 393 +/- 152 nM PMID: 9484511 AR
ZINC13778402 antagonist Compound 43   IC50 = 310 nM PMID: 9484511  
ZINC13778404 antagonist Compound 44   IC50 = 735 nM PMID: 9484511  
ZINC13780965 agonist Compound 8 Ki = 182 nM IC50 = 750 nM PMID: 9719599  
ZINC13780966 agonist Compound 9 Ki = 10 +/- 2 nM IC50 = 79 +/- 43 nM PMID: 9719599  
ZINC13780967 agonist Compound 12 Ki = 20 +/- 2 nM IC50 = 42 +/- 6 nM PMID: 9719599  
ZINC13780968 agonist Compound 13 Ki = 5 +/- 2 nM IC50 = 70 +/- 18 nM PMID: 9719599  
ZINC13796862 agonist Compound 20 Ki = 6.6 +/- 1.0 nM EC50 = 10 +/- 6 nM PMID: 10212133  
ZINC13796865 agonist Compound 19 Ki = 28.6 +/- 3.3 nM EC50 = 9.0 +/- 3.5 nM PMID: 10212133  
ZINC13796868 agonist Compound 21 Ki = 28 +/- 6 nM EC50 = 8.7 +/- 1.5 nM PMID: 10212133  
ZINC13796873 agonist Compound 24 Ki = 16.6 +/- 4.4 nM EC50 = 14 +/- 8 nM PMID: 10212133  
ZINC13796876 agonist Compound 23 Ki = 123 +/- 19 nM EC50 = 16 +/- 5 nM PMID: 10212133  
ZINC13860649 antagonist Compound 6   IC50 = 296 nM PMID: 12419390  
ZINC13860656 antagonist Compound 10 IC50 = 509 nM IC50 = 30.6 nM PMID: 12419390  
ZINC13860657 antagonist Compound 11   IC50 = 66.4 nM PMID: 12419390  
ZINC13860658 antagonist Compound 12   IC50 = 229 nM PMID: 12419390  
ZINC13860659 antagonist Compound 13   IC50 = 85 nM PMID: 12419390  
ZINC13860660 antagonist Compound 14   IC50 = 70.7 nM PMID: 12419390  
ZINC13860661 antagonist Compound 15 IC50 = 193 nM IC50 = 38 nM PMID: 12419390  
ZINC13860662 antagonist Compound 16   IC50 = 32 nM PMID: 12419390  
ZINC13860663 antagonist Compound 17 IC50 = 96 nM IC50 = 36 nM PMID: 12419390  
ZINC13860666 antagonist Compound 20   IC50 = 300 nM PMID: 12419390  
ZINC13860667 antagonist Compound 21   IC50 = 206 nM PMID: 12419390  
ZINC13860668 antagonist Compound 9   IC50 = 27 nM PMID: 18318463  
ZINC13860669 antagonist Compound 23   IC50 = 29 nM PMID: 12419390  
ZINC13860670 antagonist Compound 24   IC50 = 27 nM PMID: 12419390  
ZINC13860671 antagonist Compound 25   IC50 = 13 nM PMID: 12419390  
ZINC13860672 antagonist Compound 26   IC50 = 100.1 nM PMID: 12419390  
ZINC13860673 antagonist Compound 27   IC50 = 28 nM PMID: 12419390  
ZINC13860674 antagonist Compound 28   IC50 = 29 nM PMID: 12419390  
ZINC13860675 antagonist Compound 29   IC50 = 29 nM PMID: 12419390  
ZINC13860676 antagonist Compound 33 IC50 = 51 nM IC50 = 20 nM PMID: 12419390  
ZINC13984743 agonist Compound 7   EC50 = 3.3 nM PMID: 18722119  
ZINC13984747 agonist Compound 6 IC50 = 10.7 nM EC50 = 3.3 nM PMID: 18722119  
ZINC19132424 antagonist E-guggulsterone Ki = 201 +/- 18 nM IC50 = 1200 nM PMID: 16250653
GR
ZINC20150262 agonist Compound 9 pIC50 = 6.8 pEC50 = 7.4 PMID: 19664922  
ZINC24611178 antagonist Compound 5a Ki = 14 +/- 1.2 nM IC50 = 220 +/- 46 nM PMID: 9873612  
ZINC24611185 antagonist Compound 5c Ki = 176 +/- 29 nM IC50 = 164 +/- 39 nM PMID: 9873612  
ZINC24611193 antagonist Compound 5e Ki = 24 +/- 4 nM IC50 = 434 +/- 116 nM PMID: 9873612  
ZINC24611205 antagonist Compound 5h Ki = 2.3 +/- 0.3 nM IC50 = 1772 +/- 1021 nM PMID: 9873612  
ZINC24611223 antagonist Compound 5m Ki = 1.5 nM IC50 = 650 +/- 300 nM PMID: 9873612  
ZINC24611228 antagonist Compound 6a Ki = 184 +/- 24 nM IC50 = 1847 +/- 149 nM PMID: 9873612  
ZINC24611233 antagonist Compound 7a Ki = 113 nM IC50 = 59 +/- 13 nM PMID: 9873612  
ZINC24611248 antagonist Compound 9a Ki = 13 +/- 4 nM IC50 = 549 +/- 105 nM PMID: 9873612  
ZINC24611252 antagonist Compound 9d Ki = 57 +/- 7 nM IC50 = 1674 nM PMID: 9873612  
ZINC24611261 antagonist Compound 9h Ki = 15.5 +/- 3 nM IC50 = 496 +/- 150 nM PMID: 9873612  
ZINC24611266 antagonist Compound 9k Ki = 97 +/- 8 nM IC50 = 3331 +/- 67 nM PMID: 9873612  
ZINC24611272 antagonist Compound 10a Ki = 77 +/- 10 nM IC50 = 1144 +/- 549 nM PMID: 9873612  
ZINC24611277 antagonist Compound 12a Ki = 169 nM IC50 = 284 nM PMID: 9873612  
ZINC24611282 antagonist Compound 13a Ki = 77 nM IC50 = 416 nM PMID: 9873612  
ZINC26272578 antagonist Compound 29   IC50 = 41 nM PMID: 15081005  
ZINC26280181 agonist Compound 21 IC50 = 3.3 nM EC50 = 2.3 nM PMID: 18318463  
ZINC26282012 agonist Compound 21   EC50 = 130 nM PMID: 15081005  
ZINC26282751 agonist Compound 7 IC50 = 4.9 nM EC50 = 1.1 nM PMID: 18318463  
ZINC26284338 antagonist Compound 31   IC50 = 65 nM PMID: 15081005  
ZINC26285995 agonist Compound 33   EC50 = 1.8 nM PMID: 15081005  
ZINC26286543 antagonist Compound 30   IC50 = 23 nM PMID: 15081005  
ZINC27848185 antagonist Compound 7   IC50 = 750 nM PMID: 9871534  
ZINC27851181 antagonist Compound 9   IC50 = 1900 nM PMID: 9871534 AR
ZINC27854723 antagonist Compound 24   IC50 = 730 nM PMID: 9871534 AR
ZINC27856205 antagonist Compound 27   IC50 = 430 nM PMID: 9871534  
ZINC27856785 antagonist Compound 18   IC50 = 1000 nM PMID: 9871534 AR
ZINC28460323 antagonist Compound 7g   IC50 = 5.6 nM PMID: 17681796  
ZINC28460551 antagonist Compound 15   IC50 = 105.6 nM PMID: 15978807  
ZINC28461462 antagonist Compound 16   IC50 = 60.3 nM PMID: 15978807  
ZINC28461697 antagonist Compound 17   IC50 = 100.0 nM PMID: 15978807  
ZINC28461900 antagonist Compound 6   IC50 = 5.7 nM PMID: 15978807  
ZINC28462202 antagonist Compound 22   IC50 = 425.6 nM PMID: 15978807  
ZINC28462874 antagonist Compound 7f   IC50 = 10.9 nM PMID: 17681796  
ZINC28463643 antagonist Compound 19   IC50 = 106.0 nM PMID: 15978807  
ZINC28463710 antagonist Compound 18   IC50 = 175.4 nM PMID: 15978807  
ZINC28463772 antagonist Compound 21   IC50 = 134.7 nM PMID: 15978807  
ZINC28464563 antagonist Compound 9   IC50 = 137.3 nM PMID: 15978807  
ZINC28464930 antagonist Compound 7   IC50 = 29.0 nM PMID: 15978807  
ZINC28466178 antagonist Compound 7b pKi = 7.0 pIC50 = 5.8 PMID: 15925510  
ZINC28466742 antagonist Compound 23   IC50 = 24.8 nM PMID: 15978807  
ZINC28467118 antagonist Compound 13   IC50 = 295.4 nM PMID: 15978807  
ZINC28467122 antagonist Compound 14   IC50 = 206.6 nM PMID: 15978807  
ZINC28468703 antagonist Compound 8   IC50 = 83.6 nM PMID: 15978807  
ZINC28468948 antagonist Compound 11   IC50 = 421.3 nM PMID: 15978807  
ZINC28469035 antagonist Compound 20   IC50 = 96.8 nM PMID: 15978807  
ZINC28469232 antagonist Compound 5   IC50 = 3.3 nM PMID: 15978807  
ZINC28469743 antagonist Compound 12   IC50 = 77.9 nM PMID: 15978807  
ZINC28469750 antagonist Compound 4   IC50 = 29.6 nM PMID: 15978807  
ZINC28703533 antagonist Compound 6a   IC50 = 7.5 nM PMID: 17169557 GR
ZINC28703558 antagonist Compound 6b   IC50 = 19.0 nM PMID: 17169557 GR
ZINC28703592 antagonist Compound 6c   IC50 = 9.6 nM PMID: 17169557 GR
ZINC28703594 antagonist Compound 6d   IC50 = 9.3 nM PMID: 17169557 GR
ZINC28703596 antagonist Compound 6e   IC50 = 185.0 nM PMID: 17169557 GR
ZINC28703600 antagonist Compound 6g   IC50 = 600 nM PMID: 17169557 GR
ZINC28703603 antagonist Compound 6i   IC50 = 1.4 nM PMID: 17169557 GR
ZINC28817997 antagonist Compound 4c   IC50 = 1.4 nM PMID: 17317167 GR
ZINC28818001 antagonist Compound 4d   IC50 = 1.1 nM PMID: 17317167 GR
ZINC28818019 antagonist Compound 4e   IC50 = 8.6 nM PMID: 17317167 GR
ZINC28818021 antagonist Compound 4f   IC50 = 5.8 nM PMID: 17317167 GR
ZINC28818022 antagonist Compound 4g   IC50 = 3.2 nM PMID: 17317167 GR
ZINC28818123 antagonist Compound 4h   IC50 = 1.0 nM PMID: 17317167 GR
ZINC28818139 antagonist Compound 4i   IC50 = 12.5 nM PMID: 17317167 GR
ZINC28818168 antagonist Compound 4j   IC50 = 2.9 nM PMID: 17317167 GR
ZINC28818191 antagonist Compound 4k   IC50 = 2.7 nM PMID: 17317167 GR
ZINC28818193 antagonist Compound 4l   IC50 = 0.27 nM PMID: 17317167 GR
ZINC28818194 antagonist Compound 4m   IC50 = 0.61 nM PMID: 17317167 GR
ZINC28818200 antagonist Compound 4n   IC50 = 0.94 nM PMID: 17317167 GR
ZINC28818202 antagonist Compound 4o   IC50 = 1.6 nM PMID: 17317167 GR
ZINC28818204 antagonist Compound 4p   IC50 = 0.75 nM PMID: 17317167 GR
ZINC28818206 antagonist Compound 4q   IC50 = 3.2 nM PMID: 17317167 GR
ZINC28818208 antagonist Compound 4r   IC50 = 3.7 nM PMID: 17317167 GR
ZINC28818209 antagonist Compound 4s   IC50 = 19.5 nM PMID: 17317167 GR
ZINC28818211 antagonist Compound 4t   IC50 = 0.91 nM PMID: 17317167 GR
ZINC28818213 antagonist Compound 4u   IC50 = 34.0 nM PMID: 17317167 GR
ZINC28818230 antagonist Compound 4v   IC50 = 21.0 nM PMID: 17317167 GR
ZINC28818248 antagonist Compound 4w   IC50 = 39.0 nM PMID: 17317167 GR
ZINC28818261 antagonist Compound 4x   IC50 = 1.6 nM PMID: 17317167 GR
ZINC28824240 antagonist Compound 7b Ki = 464 +/- 158 nM IC50 = 715 +/- 61.9 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
 MR
ZINC28824243 antagonist Compound 7c Ki = 1230 +/- 260 nM IC50 = 2020 +/- 155 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
 MR
ZINC28868976 agonist Compound 8   EC50 = 2.7 nM PMID: 17681796  
ZINC28868997 agonist Compound 10   EC50 = 62.5 nM PMID: 17681796  
ZINC28869005 agonist Compound 11   IC50 = 33.7 nM PMID: 17681796  
ZINC28869038 antagonist Compound 7h   IC50 = 11.7 nM PMID: 17681796  
ZINC28869047 agonist Compound 13   EC50 = 0.5 nM PMID: 17681796  
ZINC28869055 agonist Compound 14   EC50 = 0.1 nM PMID: 17681796  
ZINC28869059 agonist Compound 15   EC50 = 1.0 nM PMID: 17681796  
ZINC28878554 antagonist Compound 1   IC50 = 205.8 nM PMID: 17027272  
ZINC28878562 antagonist Compound 2   IC50 = 56.0 nM PMID: 17027272  
ZINC28878568 antagonist Compound 3   IC50 = 54.4 nM PMID: 17027272  
ZINC28878605 antagonist Compound 8   IC50 = 27.4 nM PMID: 17027272  
ZINC28878610 antagonist Compound 9   IC50 = 30.0 nM PMID: 17027272  
ZINC28878620 antagonist Compound 10   IC50 = 42.2 nM PMID: 17027272  
ZINC28878636 antagonist Compound 11   IC50 = 100.0 nM PMID: 17027272  
ZINC28878659 antagonist Compound 12   IC50 = 5.0 nM PMID: 17027272  
ZINC28878665 antagonist Compound 13   IC50 = 29.8 nM PMID: 17027272  
ZINC28878669 antagonist Compound 14   IC50 = 13.1 nM PMID: 17027272  
ZINC28878714 antagonist Compound 20   IC50 = 9.0 nM PMID: 17027272  
ZINC28878719 antagonist Compound 21   IC50 = 37.1 nM PMID: 17027272  
ZINC28878725 antagonist Compound 22   IC50 = 9.2 nM PMID: 17027272  
ZINC28878789 antagonist Compound 23   IC50 = 8.4 nM PMID: 17027272  
ZINC28878794 antagonist Compound 24   IC50 = 8.1 nM PMID: 17027272  
ZINC28878800 antagonist Compound 25   IC50 = 14.5 nM PMID: 17027272  
ZINC28886483 antagonist Compound 1j   Relative Luciferase Activity = 54 % PMID: 17337183  
ZINC28950463 antagonist Compound 4b   IC50 = 308 nM PMID: 17258455 GR
ZINC28950465 antagonist Compound 4d   IC50 = 141 nM PMID: 17258455 GR
ZINC28950467 antagonist Compound 4e   IC50 = 101 nM PMID: 17258455 GR
ZINC28950469 antagonist Compound 5a   IC50 = 9.9 nM PMID: 17258455 GR
ZINC28950480 antagonist Compound 5c   IC50 = 1.6 nM PMID: 17258455  
ZINC28954897 antagonist Compound 2b   IC50 = 0.34 nM PMID: 17855092 GR
ZINC28954900 antagonist Compound 2c   IC50 = 0.59 nM PMID: 17855092 GR
ZINC28954903 antagonist Compound 2d   IC50 = 82 nM PMID: 17855092  
ZINC28954906 antagonist Compound 2e   IC50 = 0.98 nM PMID: 17855092 GR
ZINC28954908 antagonist Compound 2f   IC50 = 0.63 nM PMID: 17855092 GR
ZINC28954911 antagonist Compound 2g   IC50 = 18 nM PMID: 17855092 GR
ZINC28954913 antagonist Compound 2h   IC50 = 1.0 nM PMID: 17855092  
ZINC28954915 antagonist Compound 2i   IC50 = 4.6 nM PMID: 17855092 GR
ZINC29037437 agonist Compound 1a   EC50 = 513 nM PMID: 18226526  
ZINC29037443 agonist Compound 9a(RS)   EC50 = 54 nM PMID: 18226526  
ZINC29037444 agonist Compound 9b   EC50 = 222 nM PMID: 18226526  
ZINC29037460 agonist Compound 14a   EC50 = 598 nM PMID: 18226526  
ZINC29037462 antagonist Compound 14b   IC50 = 314 nM PMID: 18226526  
ZINC29037473 agonist Compound 15b   EC50 = 1340 nM PMID: 18226526  
ZINC29037489 agonist Compound 9j   EC50 = 1.6 nM PMID: 18226526  
ZINC29037492 agonist Compound 9l   EC50 = 19 nM PMID: 18226526  
ZINC29037497 agonist Compound 9o   EC50 = 0.81 nM PMID: 18226526  
ZINC29037499 agonist Compound 9p   EC50 = 0.96 nM PMID: 18226526  
ZINC29132874 antagonist Compound 46   IC50 = 164 nM PMID: 18318463  
ZINC29132961 antagonist Compound 45   IC50 = 30 nM PMID: 18318463  
ZINC29133041 antagonist Compound 44   IC50 = 4.5 nM PMID: 18318463  
ZINC29133103 antagonist Compound 43   IC50 = 194 nM PMID: 18318463  
ZINC29133189 antagonist Compound 42   IC50 = 25 nM PMID: 18318463  
ZINC29133194 antagonist Compound 41   IC50 = 30 nM PMID: 18318463  
ZINC29133274 antagonist Compound 39   IC50 = 27 nM PMID: 18318463  
ZINC29133276 antagonist Compound 40   IC50 = 13 nM PMID: 18318463  
ZINC29133278 antagonist Compound 38   IC50 = 29 nM PMID: 18318463  
ZINC29133358 antagonist Compound 37   IC50 = 15 nM PMID: 18318463  
ZINC29133362 agonist Compound 30 IC50 = 3.6 nM EC50 = 1.3 nM PMID: 18318463  
ZINC29133436 antagonist Compound 28   IC50 = 4.9 nM PMID: 18318463  
ZINC29133439 antagonist Compound 27 IC50 = 4.1 nM IC50 = 5.0 nM PMID: 18318463  
ZINC29133508 antagonist Compound 25 IC50 = 5.5 nM IC50 = 5.9 nM PMID: 18318463  
ZINC29133510 antagonist Compound 26   IC50 = 20.3 nM PMID: 18318463  
ZINC29133602 antagonist Compound 19 IC50 = 36 nM IC50 = 3.3 nM PMID: 18318463  
ZINC29133654 antagonist Compound 18 IC50 = 22 nM IC50 = 10 nM PMID: 18318463  
ZINC29133656 antagonist Compound 13 IC50 = 80 nM IC50 = 20 nM PMID: 18318463  
ZINC29133657 antagonist Compound 12   IC50 = 300 nM PMID: 18318463  
ZINC29133805 antagonist Compound 48   IC50 = 48 nM PMID: 18318463  
ZINC29133809 antagonist Compound 47   IC50 = 351 nM PMID: 18318463  
ZINC34010965 agonist Compound 4b Ki = 14 nM EC50 = 5.4 +/- 0.7 nM PMID: 18553958  
ZINC34010966 agonist Compound 5b Ki = 3.7 +/- 0.5 nM EC50 = 0.6 +/- 0.2 nM PMID: 18553958  
ZINC34203992 antagonist Compound 26   IC50 = 0.51 \B5M PMID: 21916484  
ZINC34603831 antagonist Compound 23   IC50 = 1.5 nM PMID: 23079530  
ZINC34633704 antagonist Compound 4a   IC50 = 763 nM PMID: 17258455 GR
ZINC34633705 antagonist Compound 4c   IC50 = 381 nM PMID: 17258455 GR
ZINC34633706 antagonist Compound 4f   IC50 = 275 nM PMID: 17258455 GR
ZINC34802075 antagonist Compound 4   IC50 = 0.095 nM PMID: 19216549 GR
ZINC34864982 antagonist Compound 7   IC50 = 33 nM PMID: 20638844  
ZINC34864983 agonist Compound 4   EC50 = 10 nM PMID: 19864132  
ZINC34875080 antagonist Compound 22   IC50 = 167 nM PMID: 23079530  
ZINC34875081 antagonist Compound 18   IC50 = 76 nM PMID: 23079530  
ZINC34875082 antagonist Compound 20   IC50 = 78 nM PMID: 23079530  
ZINC34875083 antagonist Compound 16   IC50 = 75 nM PMID: 23079530  
ZINC34875245 antagonist Compound 3a pKi = 7.6 pIC50 = 6.5 PMID: 16678409  
ZINC34948747 antagonist Compound 21   IC50= 10 nM PMID: 23079530  
ZINC34948752 antagonist Compound 24   IC50 = 58 nM PMID: 23079530  
ZINC34948920 antagonist Compound 19   IC50 = 9 nM PMID: 23079530  
ZINC34948922 antagonist Compound 17   IC50 = 8 nM PMID: 23079530  
ZINC34948925 antagonist Compound 27   IC50 = 30 nM PMID: 23079530  
ZINC34948927 antagonist Compound 30   IC50 = 6 nM PMID: 23079530  
ZINC34949097 antagonist Compound 35   IC50 = 57 n PMID: 23079530  
ZINC34949106 antagonist Compound 32   IC50 = 12 nM PMID: 23079530  
ZINC34949256 antagonist Compound 28   IC50 = 36 nM PMID: 23079530  
ZINC34949398 antagonist Compound 33   IC50 = 128 nM PMID: 23079530  
ZINC34949558 antagonist Compound 34   IC50 = 12 nM PMID: 23079530  
ZINC34949563 antagonist Compound 31   IC50 = 8 nM PMID: 23079530  
ZINC36398979 agonist Compound (S)-11   EC50 = 110.0 nM PMID: 18722119  
ZINC36408425 antagonist Compound (R)-14   IC50 = 10.0 nM PMID: 18722119  
ZINC36408426 antagonist Compound (S)-14   IC50 = 17.1 nM PMID: 18722119  
ZINC38344953 agonist Compound (R)-11   EC50 = 0.5 nM PMID: 18722119  
ZINC40379361 agonist Compound (-)-6 Ki = 1.2 +/- 0.2 nM EC50 = 0.4 +/- 0.1 nM PMID: 18553958  
ZINC40380426 agonist Compound 11a   EC50 = 35.8 nM PMID: 18504132  
ZINC40410016 antagonist Compound 17 IC50 = 60 nM IC50 = 11.3 nM PMID: 18722119 MR
ZINC40410253 antagonist Compound 34   IC50 = 1.2 \B5M PMID: 18586498  
ZINC40412846 antagonist Compound 29   IC50 = 1.3 \B5M PMID: 18586498  
ZINC40421229 antagonist Compound 23   IC50 = 676.7 nM PMID: 18504132  
ZINC40421716 antagonist Compound 20   IC50 = 197.4 nM PMID: 18722119  
ZINC40422589 antagonist Compound 10g   IC50 = 30.1 nM PMID: 18504132  
ZINC40422742 antagonist Compound 9   IC50 = 0.12 nM PMID: 19216549  
ZINC40423114 antagonist Compound 10w   IC50 = 22.5 nM PMID: 18504132  
ZINC40423949 antagonist Compound 10i   IC50 = 29.1 nM PMID: 18504132  
ZINC40424037 antagonist Compound 10z   IC50 = 88.0 nM PMID: 18504132  
ZINC40424053 antagonist Compound 10x   IC50 = 26.6 nM PMID: 18504132  
ZINC40424090 antagonist Compound 10k   IC50 = 34.6 nM PMID: 18504132  
ZINC40566802 antagonist Compound 3i pKi = 6.5 pIC50 = 5.7 PMID: 16678409  
ZINC40566830 antagonist Compound 3h pKi = 6.1 pIC50 = 6.3 PMID: 16678409  
ZINC40567070 antagonist Compound 3d pKi = 6.0 pIC50 = 6.4 PMID: 16678409  
ZINC40567081 antagonist Compound 3k pKi = 7.3 pIC50 = 6.8 PMID: 16678409  
ZINC40567330 antagonist Compound 3f pKi = 6.2 pIC50 = 5.9 PMID: 16678409  
ZINC40763189 antagonist Compound 3j pKi = 7.2 pIC50 = 6.6 PMID: 16678409  
ZINC40763320 antagonist Compound 3c pKi = 7.3 pIC50 = 6.7 PMID: 16678409  
ZINC40810648 antagonist Compound 3g pKi = 6.7 pIC50 = 6.2 PMID: 16678409  
ZINC40846313 agonist Compound 5a Ki = 4.8 +/- 0.6 nM EC50 = 3.4 +/- 0.4 nM PMID: 18553958  
ZINC40860294 antagonist Compound 17   IC50 = 0.16 nM PMID: 19216549  
ZINC40919037 antagonist Compound 31   IC50 = 0.074 \B5M PMID: 18586498  
ZINC40933083 antagonist Compound 21   IC50 = 3.4 \B5M PMID: 18586498  
ZINC40934107 antagonist Compound 23   IC50 = 1.6 \B5M PMID: 18586498  
ZINC40934159 antagonist Compound 32   IC50 = 0.12 \B5M PMID: 18586498  
ZINC40934255 antagonist Compound 26   IC50 = 0.25 \B5M PMID: 18586498  
ZINC40935047 antagonist Compound 27   IC50 = 1.1 \B5M PMID: 18586498  
ZINC40935356 antagonist Compound 18   IC50 = 10 \B5M PMID: 18586498  
ZINC40935358 antagonist Compound 19   IC50 = 6.8 \B5M PMID: 18586498  
ZINC40935674 antagonist Compound 33   IC50 = 0.11 \B5M PMID: 18586498  
ZINC40935983 antagonist Compound 35   IC50 = 0.88 \B5M PMID: 18586498  
ZINC40936562 antagonist Compound 28   IC50 = 0.4 \B5M PMID: 18586498  
ZINC40937612 antagonist Compound 18 IC50 = 28.4 nM IC50 = 6.6 nM PMID: 18722119 MR
ZINC40940472 antagonist Compound 24   IC50 = 500.0 nM PMID: 18722119  
ZINC40950647 antagonist Compound 6   IC50 = 0.27 nM PMID: 19216549  
ZINC40952018 agonist Compound 8   EC50 = 30.5 nM PMID: 18722119  
ZINC40981034 antagonist Compound 30   IC50 = 1.1 \B5M PMID: 18586498  
ZINC42808317 antagonist Compound 37   IC50 = 0.46 nM PMID: 19216549  
ZINC42834048 antagonist Compound 11   IC50 = 0.17 nM PMID: 19216549  
ZINC42834539 antagonist Compound 18   IC50 = 0.40 nM PMID: 19216549  
ZINC42835020 antagonist Compound 31   IC50 = 0.16 nM PMID: 19216549  
ZINC42851396 antagonist Compound 36   IC50 = 0.44 nM PMID: 19216549  
ZINC42878462 antagonist Compound 19 IC50 = 36 nM IC50 = 14.3 nM PMID: 18722119  
ZINC42878608 antagonist Compound 10y   IC50 = 65.2 nM PMID: 18504132  
ZINC42922861 antagonist Compound 10e   IC50 = 29.3 nM PMID: 18504132  
ZINC42966766 agonist Compound 16 IC50 = 8 nM EC50 = 0.5 nM PMID: 19595590  
ZINC43019667 agonist Compound 12 IC50 = 20 nM EC50 = 1.6 nM PMID: 19595590  
ZINC43020786 agonist Compound 21 IC50 = 50 nM EC50 = 200 nM PMID: 19595590  
ZINC43120912 antagonist Compound 1a   IC50 = 930 nM PMID: 19217285 GR
ZINC44351337 antagonist Compound 14   IC50 = 0.44 nM PMID: 19216549  
ZINC44352037 antagonist Compound 30   IC50 = 0.27 nM PMID: 19216549  
ZINC44352079 antagonist Compound 39   IC50 = 0.25 nM PMID: 19216549  
ZINC44352463 antagonist Compound 12   IC50 = 0.15 nM PMID: 19216549  
ZINC44359124 antagonist Compound 41   IC50 = 0.17 nM PMID: 19216549  
ZINC44359735 antagonist Compound 10   IC50 = 0.06 nM PMID: 19216549  
ZINC44460291 agonist Compound 20 IC50 = 16 nM EC50 = 25 nM PMID: 19926282  
ZINC45245726 antagonist Compound 14   IC50 = 34 nM PMID: 19864132  
ZINC45245855 antagonist Compound 22   IC50 = 225 nM PMID: 19864132  
ZINC45253265 antagonist Compound 23   IC50 = 317 nM PMID: 19864132  
ZINC45253420 antagonist Compound 26   IC50 = 316 nM PMID: 19864132  
ZINC45257037 antagonist Compound 15   IC50 = 132 nM PMID: 19864132  
ZINC45259511 antagonist Compound 25   IC50 = 456 nM PMID: 19864132  
ZINC45284159 antagonist Compound 19   IC50 = 195 nM PMID: 19864132  
ZINC45284181 antagonist Compound 24   IC50 = 490 nM PMID: 19864132  
ZINC45289237 antagonist Compound 20   IC50 = 66 nM PMID: 19864132  
ZINC45289259 antagonist Compound 21   IC50 = 79 nM PMID: 19864132  
ZINC45303322 agonist Compound 17 IC50 = 20 nM EC50 = 36 nM PMID: 19926282  
ZINC45320929 antagonist Compound 13   IC50 = 14 nM PMID: 19864132  
ZINC45335941 agonist Compound 37 IC50 = 25 nM EC50 = 163 nM PMID: 19926282  
ZINC45336689 agonist Compound 30 IC50 = 30 nM EC50 = 35 nM PMID: 19926282  
ZINC45336712 agonist Compound 22 IC50 = 12 nM EC50 = 8 nM PMID: 19926282  
ZINC45336961 agonist Compound 8 IC50 = 13 nM EC50 = 11 nM PMID: 19926282  
ZINC45336987 agonist Compound 27 IC50 = 20 nM EC50 = 41 nM PMID: 19926282  
ZINC45338593 agonist Compound 19 IC50 = 5 nM EC50 = 3 nM PMID: 19926282  
ZINC45338830 agonist Compound 24 IC50 = 12 nM EC50 = 4 nM PMID: 19926282  
ZINC45339605 agonist Compound 36 IC50 = 25 nM EC50 = 75 nM PMID: 19926282  
ZINC45349716 agonist Compound 25 IC50 = 8 nM EC50 = 0.1 nM PMID: 19926282  
ZINC45353251 agonist Compound 35 IC50 = 16 nM EC50 = 2.1 nM PMID: 19926282  
ZINC45369801 agonist Compound 18 IC50 = 6 nM EC50 = 1 nM PMID: 19926282  
ZINC45373425 agonist Compound 31 IC50 = 25 nM EC50 = 24 nM PMID: 19926282  
ZINC45373429 agonist Compound 39 IC50 = 32 nM EC50 = 3 nM PMID: 19926282  
ZINC45384973 agonist Compound 34 IC50 = 8 nM EC50 = 0.4 nM PMID: 19926282  
ZINC45390786 agonist Compound 12 IC50 = 80 nM EC50 = 10 nM PMID: 19926282  
ZINC45483737 antagonist Compound 21   IC50 = 175.1 nM PMID: 18722119  
ZINC45484353 antagonist Compound 10a   IC50 = 62.1 nM PMID: 18504132  
ZINC45495249 antagonist Compound 24   IC50 = 104 .7 nM PMID: 18504132  
ZINC45497295 antagonist Compound 10b   IC50 = 14.9 nM PMID: 18504132  
ZINC45497302 antagonist Compound 10c   IC50 = 100.0 nM PMID: 18504132  
ZINC45497559 antagonist Compound 10v   IC50 = 13.3 nM PMID: 18504132  
ZINC45497976 antagonist Compound 10h   IC50 = 15.0 nM PMID: 18504132  
ZINC45497978 antagonist Compound 10j   IC50 = 25.0 nM PMID: 18504132  
ZINC45498042 antagonist Compound 10d   IC50 = 15.7 nM PMID: 18504132  
ZINC45498263 antagonist Compound 10f   IC50 = 30.0 nM PMID: 18504132  
ZINC49035950 antagonist Compound 5   IC50 = 131 nM PMID: 20430618  
ZINC49036533 antagonist Compound 6   IC50 = 13 nM PMID: 20430618  
ZINC49036764 antagonist Compound 10   IC50 = 886 nM PMID: 20430618  
ZINC49037062 antagonist Compound 11   IC50 = 56 nM PMID: 20430618  
ZINC49037064 antagonist Compound 12   IC50 = 1130 nM PMID: 20430618  
ZINC49046069 antagonist PF-02367982   IC50 = 47 nM PMID: 20430618  
ZINC49046073 antagonist Compound 15   IC50 = 71 nM PMID: 20430618  
ZINC49047318 antagonist Compound 13   IC50 = 204 nM PMID: 20430618  
ZINC49073159 antagonist GSK1564023A   pIC50 = 5.5 PMID: 20202837 GR
ZINC49109380 antagonist GSK325971A   pIC50 = 5.9 PMID: 20202837 GR
ZINC49112168 antagonist Compound 4   IC50 = 224 nM PMID: 20430618  
ZINC49785669 antagonist Compound 8   IC50 = 173 nM PMID: 20430618  
ZINC49785670 antagonist Compound 9   IC50 = 35 nM PMID: 20430618  
ZINC49889305 antagonist Compound 19   IC50 = 0.47 nM PMID: 19216549  
ZINC53282599 antagonist Compound 16   IC50 = 0.46 nM PMID: 19216549  
ZINC55760855 antagonist Compound 15   IC50 = 0.27 nM PMID: 19216549  
ZINC56834536 antagonist Compound 1h   IC50 = 3.3 nM PMID: 19217285  
ZINC56834541 antagonist Compound 1c   IC50 = 34 nM PMID: 19217285  
ZINC58534200 antagonist Compound 14   IC50 = 115 nM PMID: 20638844  
ZINC58534294 antagonist Compound 20   IC50 = 3 nM PMID: 20638844  
ZINC58534507 antagonist Compound 16   IC50 = 266 nM PMID: 20638844  
ZINC58534581 antagonist Compound 18   IC50 = 108 nM PMID: 20638844  
ZINC58534625 antagonist Compound 15   IC50 = 3 nM PMID: 20638844  
ZINC58538182 antagonist Compound 17   IC50 = 300 nM PMID: 20638844  
ZINC58541140 antagonist Compound 13   IC50 = 800 nM PMID: 20638844  
ZINC58583489 antagonist 3S,3aR-27d   IC50 = 416 nM PMID: 20672822 MR
ZINC58591637 antagonist Compound 6   IC50 = 28 nM PMID: 20638844  
ZINC58593503 antagonist Compound 19   IC50 = 17 nM PMID: 20638844  
ZINC59348308 antagonist Compound 5   IC50 = 299 nM PMID: 12419390  
ZINC62178922 antagonist Compound 1e   IC50 = 36 nM PMID: 19217285 GR
ZINC62178927 antagonist Compound 1b   IC50 = 33 nM PMID: 19217285 GR
ZINC62178929 antagonist Compound 2b   IC50 = 7 nM PMID: 19217285 GR
ZINC62178931 antagonist Compound 2a   IC50 = 1 nM PMID: 19217285 GR
ZINC62178934 antagonist Compound 1l   IC50 = 280 nM PMID: 19217285 GR
ZINC66065899 antagonist Compound 8f Ki = 0.214 +/- 0.092 nM IC50 = 2.29 +/- 0.860 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66065900 antagonist Compound 8g Ki = 0.320 +/- 0.227 nM IC50 = 3.89 +/- 1.04 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66065901 antagonist Compound 8h Ki = 0.834 +/- 0.339 nM IC50 = 9.92 +/- 1.88 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66066028 antagonist Compound 8b Ki = 4.23 +/- 1.95 nM IC50 = 12.6 +/- 2.47 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66076536 agonist Compound 2     PMID: 21315613  
ZINC66076808 antagonist Compound 8d Ki = 0.298 +/- 0.150 nM IC50 = 3.38 +/- 0.698 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66078734 agonist Compound 3     PMID: 21315613  
ZINC66079705 antagonist Compound 8e Ki = 1.45 +/- 0.760 nM IC50 = 7.28 +/- 1.06 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66080133 antagonist Compound 8a Ki = 28.0 +/- 10.7 nM IC50 = 485 +/- 214 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC66166841 antagonist Compound 8c Ki = 0.795 +/- 0.286 nM IC50 = 6.81 +/- 1.11 nM ACS Med. Chem. Lett., 2011, 2, 2, 148
  
ZINC70631578 antagonist Compound 1g   IC50 = 56 nM PMID: 19217285 GR
ZINC70631579 antagonist Compound 1d   IC50 = 60 nM PMID: 19217285 GR
ZINC70631580 antagonist Compound 1m   IC50 = 82 nM PMID: 19217285 GR
ZINC72102693 antagonist Compound 1f   IC50 = 0.3 nM PMID: 19217285 GR
ZINC72107060 agonist Compound 6 Ki = 53 nM EC50 = 77 nM PMID: 21899328  
ZINC72122746 antagonist Compound 22   IC50 = 0.88 \B5M PMID: 21916484  
ZINC72122759 antagonist Compound 34 IC50 = 1.24 \B5M IC50 = 0.22 \B5M PMID: 21916484  
ZINC72122817 antagonist Compound 32   IC50 = 0.19 \B5M PMID: 21916484  
ZINC72122911 antagonist Compound 18   IC50 = 0.36 \B5M PMID: 21916484  
ZINC72123087 antagonist Compound 27   IC50 = 0.29 \B5M PMID: 21916484  
ZINC72123498 antagonist Compound 29   IC50 = 0.21 \B5M PMID: 21916484  
ZINC72124331 antagonist Compound 23   IC50 = 1.28 \B5M PMID: 21916484  
ZINC72124433 antagonist Compound 31   IC50 = 0.56 \B5M PMID: 21916484  
ZINC72124444 antagonist Compound 20   IC50 = 0.47 \B5M PMID: 21916484  
ZINC72127511 antagonist Compound 8 IC50 = 1.42 \B5M IC50 = 0.50 \B5M PMID: 21916484  
ZINC72127512 antagonist Compound 9   IC50 = 0.50 \B5M PMID: 21916484  
ZINC72127513 antagonist Compound 10   IC50 = 0.86 \B5M PMID: 21916484  
ZINC72127527 antagonist Compound 12   IC50 = 0.47 \B5M PMID: 21916484  
ZINC72127536 antagonist Compound 13   IC50 = 0.39 \B5M PMID: 21916484  
ZINC72127540 antagonist Compound 14   IC50 = 0.40 \B5M PMID: 21916484  
ZINC72127767 antagonist Compound 7   IC50 = 4.07 \B5M PMID: 21916484  
ZINC72127775 antagonist Compound 21   IC50 = 0.26 \B5M PMID: 21916484  
ZINC72127817 antagonist Compound 16   IC50 = 0.63 \B5M PMID: 21916484  
ZINC72127818 antagonist Compound 17   IC50 = 0.38 \B5M PMID: 21916484  
ZINC72127819 antagonist Compound 19   IC50 = 0.25 \B5M PMID: 21916484  
ZINC72127839 antagonist Compound 15   IC50 = 0.77 \B5M PMID: 21916484  
ZINC72127938 antagonist Compound 38 IC50 = 15.2 \B5M IC50 = 0.065 \B5M PMID: 21916484  
ZINC72127981 antagonist Compound 35 IC50 = 10.0 \B5M IC50 = 0.54 \B5M PMID: 21916484  
ZINC72127982 antagonist Compound 36 IC50 = 50.5 \B5M IC50 = 0.12 \B5M PMID: 21916484  
ZINC72127983 antagonist Compound 37   IC50 = 1.28 \B5M PMID: 21916484  
ZINC72128582 antagonist Compound 28   IC50 = 0.31 \B5M PMID: 21916484  
ZINC72128583 antagonist Compound 30   IC50 = 1.11 \B5M PMID: 21916484  
ZINC72128608 antagonist Compound 24   IC50 = 3.34 \B5M PMID: 21916484  
ZINC72128686 antagonist Compound 25   IC50 = 2.59 \B5M PMID: 21916484  
ZINC73200525 antagonist Compound 5a   IC50 = 101 nM PMID: 22260770 GR
ZINC73200527 antagonist Compound 5b   IC50 = 35 nM PMID: 22260770 GR
ZINC73200529 antagonist Compound 5c   IC50 = 65 nM PMID: 22260770 GR