Compound ID Pharmacological profile Compound name Binding data Activity data Bibliographic ref Cross-reactivity
CHEMBL107367 agonist Compound 20 pKi = 8.58 +/- 0.44 pEC50 = 8.83 +/- 0.67 PMID: 9836620
CHEMBL107991 agonist Compound 27 IC50 = 0.63 µM EC50 = 0.89 µM PMID: 15163205
CHEMBL1087339 agonist Compound 1 EC50 = 10.0 +/- 0.2 µM PMID: 20347594
CHEMBL1087460 agonist Compound 2 EC50 = 3.3 +/- 0.4 µM PMID: 20347594
CHEMBL1087588 agonist Compound 8 EC50 = 4.8 +/- 0.6 µM PMID: 20347594
CHEMBL1087589 agonist Compound 9 EC50 = 3.6 +/- 0.1 µM PMID: 20347594
CHEMBL1087715 agonist Compound 11 EC50 = 9.3 +/- 2.2 µM PMID: 20347594
CHEMBL1089110 agonist Compound 7 EC50 = 7.6 +/- 0.1 µM PMID: 20307981
CHEMBL1089158 agonist Compound 5 EC50 = 6.8 +/- 0.3 µM PMID: 20307981
CHEMBL1089317 agonist Compound 12 EC50 = 8.9 +/- 0.2 µM PMID: 20307981
CHEMBL1089467 agonist Compound 8 EC50 = 7.3 +/- 0.3 µM PMID: 20307981
CHEMBL1089825 agonist Compound 13 EC50 = 10.8 +/- 0.7 µM PMID: 20307981
CHEMBL1089826 agonist Compound 14 EC50 = 8.9 +/- 0.2 µM PMID: 20307981
CHEMBL1089827 agonist Compound 15 EC50 = 4.5 +/- 1.7 µM PMID: 20307981
CHEMBL1090443 agonist SP1818 IC50 = 876 nM PMID: 19879669
CHEMBL1090493 agonist Compound 9 EC50 = 9.0 +/- 0.7 µM PMID: 20307981
CHEMBL1090814 agonist Compound 10 EC50 = 13.0 +/- 0.3 µM PMID: 20307981
CHEMBL1091523 agonist Compound 4 EC50 = 6.9 +/- 0.1 µM PMID: 20307981
CHEMBL1091866 agonist Compound 6 EC50 = 7.8 +/- 0.2 µM PMID: 20307981
CHEMBL1092387 agonist Compound 23 IC50 = 47 µM EC50 = 0.18 µM PMID: 20219371
CHEMBL1092559 agonist Compound 16 IC50 = 13 µM EC50 = 0.56 µM PMID: 20219371
CHEMBL1096557 agonist Compound 4 PMID: 20036122
CHEMBL109731 agonist Compound 3 IC50 = 2.9 µM EC50 = 2.8 µM PMID: 15163205
CHEMBL1098027 agonist Compound 10 EC50 = 8.6 +/- 3.0 µM PMID: 20347594
CHEMBL109975 agonist Compound 9 IC50 = 1.8 µM EC50 = 1.6 µM PMID: 15163205
CHEMBL110071 agonist Compound 10 IC50 = 5.1 µM EC50 = 3.6 µM PMID: 15163205
CHEMBL110743 agonist Compound 14 IC50 = 0.44 µM EC50 = 1.0 µM PMID: 15163205 PPAR_alpha
CHEMBL111161 agonist Compound 26 IC50 = 1.4 µM EC50 = 0.67 µM PMID: 15163205 PPAR_alpha
CHEMBL111271 agonist Compound 25 IC50 = 1.2 µM EC50 = 0.75 µM PMID: 15163205 PPAR_alpha
CHEMBL111480 agonist Compound 40 IC50 = 1.4 µM EC50 = 0.36 µM PMID: 15163205 PPAR_alpha
CHEMBL112973 agonist Compound 38 IC50 = 4.7 µM EC50 = 1.0 µM PMID: 15163205 PPAR_alpha
CHEMBL113324 agonist Compound 28 IC50 = 0.37 µM EC50 = 2.8 µM PMID: 15163205
CHEMBL114286 agonist Compound 4 IC50 = 1.7 µM EC50 = 6.8 µM PMID: 15163205
CHEMBL116920 agonist Compound 6 EC50 = 0.09 µM PMID: 15177462
CHEMBL116947 agonist Compound 73 EC50 = 6.2 µM PMID: 12904063 PPAR_alpha
CHEMBL1170264 agonist Compound 16 EC50 = 11.0 +/- 0.3 µM PMID: 20503989
CHEMBL1170852 agonist Compound 17 EC50 = 10.3 +/- 1.6 µM PMID: 20503989
CHEMBL1171652 agonist Compound 18 max. activation = 33% at 6 µM PMID: 20503989
CHEMBL1171831 agonist Compound 19 EC50 = 7.0 +/- 0.9 µM PMID: 20503989
CHEMBL1171832 agonist Compound 20 max. activation = 32% at 10 µM PMID: 20503989
CHEMBL1171834 agonist Compound 22 EC50 = 6.6 +/- 0.4 µM PMID: 20503989
CHEMBL1172000 agonist Compound 23 EC50 = 12.1 +/- 0.2 µM PMID: 20503989
CHEMBL1172001 agonist Compound 24 EC50 = 4.3 +/- 0.9 µM PMID: 20503989
CHEMBL1172002 agonist Compound 25 EC50 = 11.0 +/- 0.1 µM PMID: 20503989
CHEMBL1172003 agonist Compound 9 EC50 = 8.8 +/- 0.4 µM PMID: 20503989
CHEMBL1172016 agonist Compound 13 EC50 = 10.0 +/- 1.2 µM PMID: 20503989
CHEMBL1172019 agonist Compound 12 EC50 = 8.9 +/- 2.1 µM PMID: 20503989
CHEMBL1172222 agonist Compound 11 max. activation = 31% at 20 µM PMID: 20503989
CHEMBL1173121 agonist Compound 15 max. activation = 23% at 10 µM PMID: 20503989
CHEMBL1173376 agonist Compound 14 EC50 = 7.5 +/- 1.4 µM PMID: 20503989
CHEMBL1173499 agonist Compound 7 EC50 = 6.1 +/- 0.2 µM PMID: 20503989
CHEMBL117402 agonist Compound 17 EC50 = 3.02 µM PMID: 15177462
PPAR_alpha
CHEMBL117578 agonist Compound 6 IC50 = 0.144 µM EC50 = 0.051 µM PMID: 14505666
CHEMBL117738 agonist Compound 9 IC50 = 0.15 µM EC50 = 0.21 µM PMID: 14505666 PPAR_alpha
CHEMBL118198 agonist Compound 65 EC50 = 10.0 µM PMID: 12904063
CHEMBL118251 agonist Compound 14 IC50 = 0.64 µM EC50 = 0.035 µM PMID: 14505666 PPAR_alpha
CHEMBL118279 agonist Compound 77 EC50 = 5.4 µM PMID: 12904063 PPAR_alpha
CHEMBL118483 agonist Compound 78 EC50 = 3.0 µM PMID: 12904063 PPAR_alpha
CHEMBL118577 agonist Compound 19 EC50 = 3.80 µM PMID: 15177462
PPAR_alpha
CHEMBL118756 agonist Compound 12 IC50 = 0.49 µM EC50 = 0.019 µM PMID: 14505666 PPAR_alpha
CHEMBL118816 agonist Compound 21 EC50 = 2.88 µM PMID: 15177462
PPAR_alpha
CHEMBL118939 agonist Compound 17 EC50 = 2000 nM PMID: 16275077
PPAR_alpha
CHEMBL119066 agonist Compound 19 IC50 = 1.76 µM EC50 = 0.09 µM PMID: 14505666
CHEMBL119097 agonist Compound 8 EC50 = 0.83 µM PMID: 15177462
CHEMBL119217 agonist Compound 13 EC50 = 3.43 µM PMID: 15177462
CHEMBL119496 agonist Compound 8 IC50 = 0.064 µM EC50 = 0.11 µM PMID: 14505666 PPAR_alpha
CHEMBL119791 agonist Compound 75 EC50 = 4.0 µM PMID: 12904063 PPAR_alpha
CHEMBL119795 agonist Compound 11 EC50 = 0.69 µM PMID: 15177462 PPAR_beta
CHEMBL120009 agonist Compound 20 EC50 = 0.40 µM PMID: 11738577
PPAR_alpha
CHEMBL120570 agonist Compound 2 IC50 = 0.037 µM EC50 = 0.039 µM PMID: 14505666 PPAR_alpha
CHEMBL1206083 agonist Compound 26b EC50 = 1195 nM PMID: 16137885
CHEMBL1206084 agonist Compound 26a EC50 = 1503 nM PMID: 16137885
CHEMBL1206086 agonist Compound 27b EC50 = 1566 nM PMID: 16137885
CHEMBL1207269 agonist Compound 23b EC50 = 617 nM PMID: 16137885 PPAR_alpha
CHEMBL120744 agonist Compound 16 EC50 = 2.8 µM PMID: 12904063
PPAR_alpha
CHEMBL1208363 agonist Compound 13 EC50 = 1.5 +/- 0.4 µM PMID: 19775169 PPAR_alpha
CHEMBL1208366 agonist Compound 11 EC50 = 9.1 +/- 0.9 µM PMID: 19775169 PPAR_alpha
CHEMBL121 agonist rosiglitazone IC50 = 0.092 µM EC50 = 0.220 µM PMID: 16451087
CHEMBL1214886 agonist Compound 3g-5 EC50 = 2.9 µM PMID: 20656494
CHEMBL1214887 agonist Compound 3g-6 EC50 = 3.5 µM PMID: 20656494
CHEMBL121719 agonist Compound 4g EC50 = 1.6 µM PMID: 10714503
CHEMBL122009 agonist Compound 32 EC50 = 3.0 µM PMID: 12904063 PPAR_alpha
CHEMBL122070 agonist Compound 74 EC50 = 2.4 µM PMID: 12904063
PPAR_alpha
CHEMBL122417 agonist Compound 11 IC50 = 0.34 µM EC50 = 0.081 µM PMID: 14505666 PPAR_alpha
CHEMBL122418 agonist Compound 10 IC50 = 0.059 µM EC50 = 0.08 µM PMID: 14505666 PPAR_alpha
CHEMBL123257 agonist Compound 4o EC50 = 1.6 µM PMID: 10714503
CHEMBL123749 agonist Compound 4l EC50 = 0.19 µM PMID: 10714503
CHEMBL124421 agonist Compound 4k EC50 = 1.1 µM PMID: 10714503
CHEMBL125176 agonist Compound 4f EC50 = 0.40 µM PMID: 10714503
CHEMBL125177 agonist Compound 4b EC50 = 2.8 µM PMID: 10714503
CHEMBL125363 agonist Compound 4d EC50 = 7.9 µM PMID: 10714503
CHEMBL125659 agonist Compound 4i EC50 = 0.33 µM PMID: 10714503
CHEMBL125894 agonist Compound 4n EC50 = 0.80 µM PMID: 10714503
CHEMBL125895 agonist Compound 4m EC50 = 0.64 µM PMID: 10714503
CHEMBL144877 agonist Compound 4 pKi = 6.12 +/- 0.03 pEC50 = 6.16 +/- 0.08 PMID: 9836620
CHEMBL145824 agonist Compound 49 pKi = 8.38 +/- 0.07 pEC50 = 7.76 +/- 0.56 PMID: 9836622
CHEMBL145829 agonist Compound 30 pKi = 6.79 pEC50 = 5.91 +/- 0.02 PMID: 9836620
CHEMBL145886 agonist Compound 30 pKi = 8.64 +/- 0.01 pEC50 = 6.93 +/- 0.41 PMID: 9836622
CHEMBL145938 agonist Compound 53 pKi = 6.09 +/- 0.01 pEC50 = 6.68 +/- 0.57 PMID: 9836622
CHEMBL145958 agonist Compound 41 pKi = 8.49 +/- 0.04 pEC50 = 7.07 +/- 0.51 PMID: 9836622
CHEMBL146123 agonist Compound 27 pKi = 6.91 +/- 0.05 pEC50 = 5.66 +/- 0.01 PMID: 9836620
CHEMBL146201 agonist Compound 3 pKi = 5.88 +/- 0.01 pEC50 = 6.31 PMID: 9836620
CHEMBL146217 agonist Compound 25 pKi = 8.29 +/- 0.23 pEC50 = 7.62 +/- 0.05 PMID: 9836622
CHEMBL146231 agonist Compound 23 pKi = 8.36 +/- 0.16 pEC50 = 6.93 +/- 0.22 PMID: 9836621
CHEMBL146258 agonist Compound 43 pKi = 8.06 +/- 0.02 pEC50 = 7.05 +/- 0.18 PMID: 9836622
CHEMBL146301 agonist Compound 25 pKi = 9.01 +/- 0.01 pEC50 = 8.62 +/- 0.36 PMID: 9836621
CHEMBL146322 agonist Compound 22 pKi = 7.48 +/- 0.01 pEC50 = 5.87 +/- 0.01 PMID: 9836620
CHEMBL146355 agonist Compound 26 pKi = 8.65 +/- 0.03 pEC50 = 8.03 +/- 0.1 PMID: 9836622
CHEMBL146530 agonist Compound 52 pKi = 8.47 +/- 0.01 pEC50 = 7.61 +/- 0.09 PMID: 9836622
CHEMBL146562 agonist Compound 40 pKi = 8.63 +/- 0.03 pEC50 = 7.20 +/- 0.34 PMID: 9836622
CHEMBL146579 agonist Compound 23 pKi = 8.57 +/- 0.04 pEC50 = 7.40 +/- 0.4 PMID: 9836622
CHEMBL146584 agonist Compound 39 pKi = 8.56 +/- 0.02 pEC50 = 7.34 +/- 0.16 PMID: 9836622
CHEMBL146614 agonist Compound 21 pKi = 7.55 +/- 0.08 pEC50 = 6.02 +/- 0.14 PMID: 9836620
CHEMBL146637 agonist Compound 24 pKi = 8.58 pEC50 = 7.93 +/- 0.46 PMID: 9836622
CHEMBL146650 agonist Compound 26 pKi = 8.58 +/- 0.09 pEC50 = 7.63 +/- 0.32 PMID: 9836621
CHEMBL146687 agonist Compound 62 pKi = 6.60 +/- 0.14 pEC50 = 6.25 +/- 0.36 PMID: 9836622
CHEMBL146806 agonist Compound 18 pKi = 7.56 +/- 0.12 pEC50 = 5.91 +/- 0.20 PMID: 9836621
CHEMBL146821 agonist Compound 38 pKi = 7.40 +/- 0.13 pEC50 = 8.11 +/- 0.52 PMID: 9836622
CHEMBL146822 agonist Compound 26 pKi = 8.48 +/- 0.10 pEC50 = 7.33 PMID: 9836620
CHEMBL147021 agonist Compound 28 pKi = 8.55 +/- 0.15 pEC50 = 8.07 +/- 0.06 PMID: 9836622
CHEMBL147090 agonist Compound 17 pKi = 9.06 +/- 0.05 pEC50 = 8.68 +/- 0.07 PMID: 9836621
CHEMBL147095 agonist Compound 14 pKi = 9.07 +/- 0.02 pEC50 = 9.61 +/- 0.17 PMID: 9836621 PPAR_alpha
CHEMBL147282 agonist Compound 33 pKi = 7.18 +/- 0.02 pEC50 = 6.12 +/- 0.37 PMID: 9836622
CHEMBL147384 agonist Compound 11 pKi = 8.80 +/- 0.06 pEC50 = 9.90 +/- 0.47 PMID: 9836621 PPAR_alpha
CHEMBL147694 agonist Compound 23 pKi = 7.49 +/- 0.01 pEC50 = 5.94 +/- 0.01 PMID: 9836620
CHEMBL147826 agonist Compound 28 pKi = 8.43 +/- 0.02 pEC50 = 6.33 +/- 0.10 PMID: 9836620
CHEMBL147912 agonist Compound 32 pKi = 7.27 +/- 0.1 pEC50 = 6.13 +/- 0.11 PMID: 9836622
CHEMBL147935 agonist Compound 9 pKi = 8.90 +/- 0.05 EC50 = 8.43 +/- 0.16 PMID: 9836621
CHEMBL148060 agonist Compound 24 pKi = 7.07 +/- 0.73 pEC50 = 6.24 +/- 0.02 PMID: 9836620
CHEMBL148301 agonist Compound 17 pKi = 8.04 +/- 0.11 pEC50 = 6.44 +/- 0.07 PMID: 9836620
CHEMBL148459 agonist Compound 13 pKi = 8.72 +/- 0.05 pEC50 = 8.89 +/- 0.15 PMID: 9836621 PPAR_alpha
CHEMBL148797 agonist Compound 8 pKi = 8.75 +/- 0.24 pEC50 = 8.97 +/- 0.42 PMID: 9836621 PPAR_alpha
CHEMBL148950 agonist Compound 16 pKi = 8.85 +/- 0.14 pEC50 = 8.74 +/- 0.23 PMID: 9836621
CHEMBL149147 agonist Compound 50 pKi= 6.19 +/- 0.00 pEC50 = 5.12 +/- 0.52 PMID: 9836622
CHEMBL149309 agonist Compound 47 pKi = 6.81 +/- 0.07 pEC50 = 5.03 +/- 0.22 PMID: 9836622
CHEMBL149381 agonist Compound 31 pKi = 8.25 +/- 0.04 pEC50 = 7.49 +/- 0.33 PMID: 9836622
CHEMBL149647 agonist Compound 6 pKi = 8.70 +/- 0.01 pEC50 = 7.09 +/- 0.39 PMID: 9836621
CHEMBL149714 agonist Compound 35 PKI = 8.19 +/- 0.04 pEC50 = 7.74 +/- 0.35 PMID: 9836622
CHEMBL149715 agonist Compound 21 pKi = 6.77 +/- 0.04 pEC50 = 7.29 +/- 0.13 PMID: 9836621
CHEMBL149780 agonist Compound 45 pKi = 8.59 +/- 0.07 pEC50 = 8.08 +/- 0.6 PMID: 9836622
CHEMBL149835 agonist Compound 5 pKi = 8.59 +/- 0.05 pEC50 = 6.42 +/- 0.29 PMID: 9836621
CHEMBL149876 agonist Compound 22 pKi = 9.11 +/- 0.11 pEC50 = 8.74 +/- 0.19 PMID: 9836621
CHEMBL150215 agonist Compound 27 pKi = 8.57 +/- 0.02 pEC50 = 7.78 +/- 0.3 PMID: 9836622
CHEMBL150232 agonist Compound 28 pKi = 8.55 +/- 0.15 pEC50 = 8.07 +/- 0.06 PMID: 9836622
CHEMBL1630380 agonist Compound 1i EC50 = 100.2 nM PMID: 21074432
PPAR_alpha
CHEMBL1630384 agonist Compound 2i EC50 = 290.3 nM PMID: 21074432
PPAR_alpha
CHEMBL1630385 agonist Compound 2h EC50 = 270.6 nM PMID: 21074432 PPAR_beta
CHEMBL165484 agonist Compound 3l EC50 = 0.76 +/- 0.28 µM PMID: 11831892
CHEMBL165539 agonist Compound 3i EC50 = 12.1 +/- 4.0 µM PMID: 11831892 PPAR_alpha
CHEMBL166408 agonist Compound 3c EC50 = 16.7 +/- 1.2 µM PMID: 11831892
CHEMBL166539 agonist Compound 3j EC50 = 0.49 +/- 0.071 µM PMID: 11831892
CHEMBL166572 agonist Compound 3k EC50 = 1.2 +/- 0.41 µM PMID: 11831892
CHEMBL166628 agonist Compound 3o EC50 = 0.091 +/- 0.073 µM PMID: 11831892
CHEMBL166687 agonist Compound 3g EC50 = 3.4 +/- 1.4 µM PMID: 11831892
CHEMBL167043 agonist Compound 3h EC50 = 0.46 +/- 0.13 µM PMID: 11831892
CHEMBL167084 agonist Compound 3d EC50 = 12.6 +/- 5.5 µM PMID: 11831892
CHEMBL167352 agonist Compound 3n EC50 = 0.76 +/- 0.13 µM PMID: 11831892 PPAR_alpha
CHEMBL167378 agonist Compound 3b EC50 = 9.8 +/- 5.0 µM PMID: 11831892 PPAR_alpha
CHEMBL167963 agonist Compound 3m EC50 = 0.75 +/- 0.35 µM PMID: 11831892
CHEMBL168033 agonist Compound 3a EC50 = 1.7 +/- 1.1 µM PMID: 11831892
CHEMBL168166 agonist Compound 3f EC50 = 3.7 +/- 1.2 µM PMID: 11831892
CHEMBL174798 agonist Compound 41 EC50 = 1000 nM PMID: 14695833
CHEMBL175589 agonist Compound 40 EC50 = 149 nM PMID: 14695833
CHEMBL175637 agonist Compound 38 EC50 = 644 nM PMID: 14695833
CHEMBL176251 agonist Compound 49 EC50 = 534 nM PMID: 14695833
CHEMBL176770 agonist Compound 15 EC50 = 234 nM PMID: 14695833
CHEMBL177552 agonist Compound 28 EC50 = 1000 nM PMID: 14695833
CHEMBL177755 agonist Compound 44 EC50 = 10 nM PMID: 14695833
CHEMBL177830 agonist Compound 36 EC50 = 208 nM PMID: 14695833
CHEMBL177854 agonist Compound 11 EC50 = 243 nM PMID: 14695833
CHEMBL177877 agonist Compound 43 EC50 = 264 nM PMID: 14695833
CHEMBL178235 agonist Compound 6 Fold induction = 2.5 PMID: 15664804
CHEMBL178244 agonist Compound 2b Fold induction = 3.8 PMID: 15664804
CHEMBL178536 agonist Compound 16 EC50 = 300 nM PMID: 14695833
CHEMBL179733 agonist Compound 23 EC50 = 300 nM PMID: 14695833
CHEMBL179789 agonist Compound 7 Fold induction = 5.7 PMID: 15664804
CHEMBL179853 agonist Compound 13a Fold induction = 1.2 PMID: 15664804
CHEMBL180078 agonist Compound 11 Fold induction = 1.5 PMID: 15664804
CHEMBL180083 agonist Compound 4 Fold induction = 3.5 PMID: 15664804
CHEMBL1801440 agonist Compound 18l EC50 = 0.34 µM PMID: 20850970
CHEMBL180311 agonist Compound 2c Fold induction = 1.7 PMID: 15664804
CHEMBL180338 agonist Compound 10a Fold induction = 7.8 PMID: 15664804
CHEMBL180400 agonist Compound 5 Fold induction = 1.4 PMID: 15664804
CHEMBL180696 agonist Compound 10b Fold induction = 6.6 PMID: 15664804
CHEMBL180820 agonist Compound 2e Fold induction = 1.9 PMID: 15664804
CHEMBL180898 agonist Compound 13b Fold induction = 1.3 PMID: 15664804
CHEMBL181175 agonist Compound 12a Fold induction = 2.0 PMID: 15664804
CHEMBL181198 agonist Compound 8 Fold induction = 5.1 PMID: 15664804
CHEMBL1813188 agonist Compound 11a EC50 = 23 µM PMID: 21514830
PPAR_alpha
CHEMBL1813192 agonist Compound 12b EC50 = 12 µM PMID: 21514830
CHEMBL1813194 agonist Compound 13a EC50 = 11 µM PMID: 21514830
PPAR_alpha
CHEMBL1813195 agonist Compound 13b EC50 = 17 µM PMID: 21514830
PPAR_alpha
CHEMBL1813199 agonist Compound 13f EC50 = 7.9 µM PMID: 21514830
PPAR_alpha
CHEMBL1813200 agonist Compound (S)-13c EC50 = 7.1 µM PMID: 21514830 PPAR_beta
CHEMBL1813201 agonist Compound (R)-13c EC50 = 12 µM PMID: 21514830
CHEMBL1813202 agonist Compound (S)-13d EC50 = 3.2 µM PMID: 21514830 PPAR_beta
CHEMBL1813203 agonist Compound (R)-13d EC50 = 6.9 µM PMID: 21514830 PPAR_beta
CHEMBL1813204 agonist Compound (S)-13e EC50 = 5.2 µM PMID: 21514830 PPAR_beta
CHEMBL1817687 agonist Compound 10 EC50 = 4.8 +/- 0.9 µM PMID: 21873070
CHEMBL181930 agonist Compound 7 EC50 = 4.7 +/- 1.8 µM PMID: 21873070
CHEMBL1819392 agonist Compound 9 EC50 = 3.4 +/- 0.1 µM PMID: 21873070
CHEMBL1819393 agonist Compound 11 EC50 = 3.7 +/- 0.8 µM PMID: 21873070
CHEMBL1819394 agonist Compound 12 EC50 = 2.2 +/- 0.7 µM PMID: 21873070
CHEMBL1819396 agonist Compound 14 EC50 = 10.8 +/- 0.8 µM PMID: 21873070
CHEMBL1819481 agonist Compound 20 EC50 = 1.1 +/- 0.1 µM PMID: 21873070
CHEMBL1819482 agonist Compound 21 EC50 = 2.5 +/- 0.4 µM PMID: 21873070
CHEMBL1819483 agonist Compound 22 EC50 = 1.5 +/- 0.5 µM PMID: 21873070
CHEMBL184133 agonist GW409544 Ki = 0.001 µM EC50 = 0.0002 µM PMID: 15293980
CHEMBL189066 agonist Compound 36 IC50 = 0.26 µM EC50 = 0.197 µM PMID: 15974597 PPAR_alpha
CHEMBL1933821 agonist Compound 3e EC50 = 40 nM PMID: 22209730
CHEMBL1933822 agonist Compound 3d EC50 = 10 nM PMID: 22209730
CHEMBL1933823 agonist Compound 3c EC50 = 16 nM PMID: 22209730
CHEMBL1933824 agonist Compound 3f EC50 = 21 nM PMID: 22209730
CHEMBL1933825 agonist Compound 3g EC50 = 17 nM PMID: 22209730
CHEMBL1933826 agonist Compound 3h EC50 = 150 nM PMID: 22209730
CHEMBL1933827 agonist Compound 3i EC50 = 110 nM PMID: 22209730
CHEMBL1933828 agonist Compound 3j EC50 = 260 nM PMID: 22209730
CHEMBL1933829 agonist Compound 18a EC50 = 7.5 nM PMID: 22209730
CHEMBL1933830 agonist Compound 18b EC50 = 31 nM PMID: 22209730
CHEMBL1933831 agonist Compound 18c EC50 = 14 nM PMID: 22209730
CHEMBL1933832 agonist Compound 18d EC50 = 120 nM PMID: 22209730
CHEMBL1933833 agonist Compound 24a EC50 = 13 nM PMID: 22209730
CHEMBL1933834 agonist Compound 24b EC50 = 8.4 nM PMID: 22209730
CHEMBL1933835 agonist Compound 24c EC50 = 13 nM PMID: 22209730
CHEMBL1933836 agonist Compound 24d EC50 = 11 nM PMID: 22209730
CHEMBL1933838 agonist Compound 34c EC50 = 67 nM PMID: 22209730
CHEMBL1933839 agonist Compound 34d EC50 = 29 nM PMID: 22209730
CHEMBL1933840 agonist Compound 30a EC50 = 20 nM PMID: 22209730
CHEMBL1933841 agonist Compound 30b EC50 = 9.3 nM PMID: 22209730
CHEMBL1933842 agonist Compound 30c EC50 = 8.3 nM PMID: 22209730
CHEMBL1933843 agonist Compound 30d EC50 = 9.0 nM PMID: 22209730
CHEMBL1933844 agonist Compound 25a EC50 = 8.2 nM PMID: 22209730
CHEMBL1933845 agonist Compound 25c EC50 = 12 nM PMID: 22209730
CHEMBL194698 agonist Compound 14a EC50 = 642 nM PMID: 16137885 PPAR_alpha
CHEMBL1956349 agonist Compound 14 EC50 = 3.5 +/- 0.3 µM PMID: 22341573 PPAR_alpha
CHEMBL1956350 agonist Compound 15 EC50 = 5.2 +/- 1.2 µM PMID: 22341573 PPAR_alpha
CHEMBL1956358 agonist Compound 4 EC50 = 41 +/- 4 µM PMID: 22341573 PPAR_alpha
CHEMBL1956359 agonist Compound 5 EC50 = 19 +/- 4 µM PMID: 22341573 PPAR_alpha
CHEMBL1956361 agonist Compound 8 EC50 = 30 +/- 20 µM PMID: 22341573
CHEMBL1956365 agonist Compound 11 EC50 = 14.1 +/- 2.9 µM PMID: 22341573 PPAR_alpha
CHEMBL1956366 agonist Compound 12 EC50 = 5.8 +/- 3.9 µM PMID: 22341573 PPAR_alpha
CHEMBL1956367 agonist Compound 13 EC50 = 4.9 +/- 1.5 µM PMID: 22341573 PPAR_alpha
CHEMBL1956368 agonist Compound 16 EC50 = 2.4 +/- 0.5 µM PMID: 22341573 PPAR_alpha
CHEMBL1956369 agonist Compound 17 EC50 = 11.6 +/- 3.3 µM PMID: 22341573
CHEMBL1956370 agonist Compound 18 EC50 = 32 +/- 19 µM PMID: 22341573 PPAR_alpha
CHEMBL1956371 agonist Compound 19 EC50 = 16.4 +/- 0.8 µM PMID: 22341573 PPAR_alpha
CHEMBL1962562 agonist Compound 14j EC50 = 0.31 µM PMID: 22197396
CHEMBL1963516 agonist Compound 18d EC50 = 120 nM PMID: 22209730
CHEMBL196736 agonist Compound 18a EC50 = 340 nM PMID: 16137885
CHEMBL197256 agonist Compound 16a EC50 = 28 nM PMID: 16137885
CHEMBL197527 agonist Compound 26 IC50 = 1.709 µM EC50 = 5.900 µM PMID: 16366601
CHEMBL197623 agonist Compound 24b EC50 = 1546 nM PMID: 16137885
CHEMBL197684 agonist Compound 22b EC50 = 1413 nM PMID: 16137885 PPAR_alpha
CHEMBL197738 agonist Compound 20 IC50 = 1.298 µM EC50 = 3.030 µM PMID: 16366601
CHEMBL197866 agonist Compound 63 EC50 = 14 nM PMID: 16275080 PPAR_alpha
CHEMBL197971 agonist Compound 62 EC50 = 84 nM PMID: 16275080 PPAR_alpha
CHEMBL198023 agonist Compound 60 EC50 = 43 nM PMID: 16275080 PPAR_alpha
CHEMBL198170 agonist Compound 25a EC50 = 1356 nM PMID: 16137885 PPAR_alpha
CHEMBL198288 agonist Compound 38 EC50 = 523 nM PMID: 16275080 PPAR_alpha
CHEMBL198406 agonist Compound 22 PMID: 16290140 PPAR_alpha
CHEMBL199372 agonist Compound 65 EC50 = 738 nM PMID: 16275080 PPAR_alpha
CHEMBL199380 agonist Compound 21 PMID: 16290140
CHEMBL199432 agonist Compound 52 EC50 = 49 nM PMID: 16275080 PPAR_alpha
CHEMBL199449 agonist Compound 39 EC50 = 45 nM PMID: 16275080 PPAR_alpha
CHEMBL199459 agonist Compound 4 EC50 = 177 nM PMID: 16275080 PPAR_alpha
CHEMBL199472 agonist Compound 14 PMID: 16290140
CHEMBL199509 agonist Compound 36 EC50 = 124 nM PMID: 16275080 PPAR_alpha
CHEMBL199559 agonist Compound 56 EC50 = 21 nM PMID: 16275080 PPAR_alpha
CHEMBL199579 agonist Compound 49 EC50 = 19 nM PMID: 16275080 PPAR_alpha
CHEMBL199645 agonist Compound 61 EC50 = 77 nM PMID: 16275080 PPAR_alpha
CHEMBL199703 agonist Compound 46 EC50 = 40 nM PMID: 16275080 PPAR_alpha
CHEMBL199782 agonist Compound 9 EC50 = 1860 nM PMID: 16275080
CHEMBL199794 agonist Compound 50 EC50 = 1 nM PMID: 16275080 PPAR_alpha
CHEMBL199814 agonist Compound 22 EC50 = 632 nM PMID: 16275080
CHEMBL199819 agonist Compound 6 EC50 = 52 nM PMID: 16275080 PPAR_alpha
CHEMBL199823 agonist Compound 2 EC50 = 5640 nM PMID: 16275080 PPAR_alpha
CHEMBL199855 agonist Compound 70 EC50 = 396 nM PMID: 16275080 PPAR_alpha
CHEMBL199928 agonist Compound 44 EC50 = 34 nM PMID: 16275080 PPAR_alpha
CHEMBL200043 agonist Compound 42 EC50 = 136 nM PMID: 16275080 PPAR_alpha
CHEMBL200045 agonist Compound 35 EC50 = 168 nM PMID: 16275080 PPAR_alpha
CHEMBL200071 agonist Compound 41 EC50 = 212 nM PMID: 16275080 PPAR_alpha
CHEMBL200122 agonist Compound 51 EC50 = 42 nM PMID: 16275080 PPAR_alpha
CHEMBL200138 agonist Compound 71 EC50 = 6 nM PMID: 16275080 PPAR_alpha
CHEMBL200207 agonist Compound 73 EC50 = 762 nM PMID: 16275080 PPAR_alpha
CHEMBL20024608 agonist Compound 16 EC50 = 3.1 nM PMID: 22503460
CHEMBL200304 agonist Compound 11j EC50 = 5 nM PMID: 17157019 PPAR_alpha
CHEMBL200305 agonist Compound 15 EC50 = 196 nM PMID: 16275080
CHEMBL200495 agonist Compound 5 IC50 = 0.152 µM EC50 = 0.230 µM PMID: 16451087
PPAR_alpha
CHEMBL200610 agonist Compound 30 EC50 = 617 nM PMID: 16275080
CHEMBL200746 agonist Compound 27 EC50 = 306 nM PMID: 16275080 PPAR_alpha
CHEMBL200760 agonist Compound 28 EC50 = 46 nM PMID: 16275080 PPAR_alpha
CHEMBL200840 agonist Compound 11 EC50 = 45 nM PMID: 16275080 PPAR_alpha
CHEMBL200916 agonist Compound 72 EC50 = 37 nM PMID: 16275080 PPAR_alpha
CHEMBL200943 agonist Compound 31 EC50 = 294 nM PMID: 16275080 PPAR_alpha
CHEMBL201036 agonist Compound 10j IC50 = 0.824 µM EC50 = 2.300 µM PMID: 16451087 PPAR_alpha
CHEMBL2011544 agonist Compound 11 EC50 = 3.6 +/- 0.7 µM PMID: 22381047 PPAR_beta
CHEMBL201280 agonist Compound 34 EC50 = 290 nM PMID: 16275080 PPAR_alpha
CHEMBL201803 agonist Compound 10c EC50 = 1600 nM PMID: 16275077
PPAR_alpha
CHEMBL201832 agonist Compound 10b EC50 = 500 nM PMID: 16275077
PPAR_alpha
CHEMBL201880 agonist Compound 10k IC50 = 0.050 µM EC50 = 0.070 µM PMID: 16451087
PPAR_alpha
CHEMBL202087 agonist Compound 29 EC50 = 347 nM PMID: 16275080
CHEMBL202140 agonist Compound 10f IC50 = 1.287 µM EC50 = 4.000 µM PMID: 16451087 PPAR_beta
CHEMBL2021928 agonist Compound 8g EC50 = 5.2 nM PMID: 22503460
CHEMBL2021930 agonist Compound 8r EC50 = 1.1 nM PMID: 22503460
CHEMBL2022125 agonist Compound 8k EC50 = 7.4 nM PMID: 22503460
CHEMBL2022126 agonist Compound 8m EC50 = 80 nM PMID: 22503460
CHEMBL2022127 agonist Compound 8o EC50 = 59 nM PMID: 22503460
CHEMBL2022128 agonist Compound 8p EC50 = 320 nM PMID: 22503460
CHEMBL2022129 agonist Compound 8q EC50 = 15 nM PMID: 22503460
CHEMBL2022130 agonist Compound 23b EC50 = 290 nM PMID: 22503460
CHEMBL2022131 agonist Compound 32a EC50 = 32 nM PMID: 22503460
CHEMBL2022132 agonist Compound 32b EC50 = 38 nM PMID: 22503460
CHEMBL2022133 agonist Compound 29a EC50 = 48 nM PMID: 22503460
CHEMBL2022134 agonist Compound 29b EC50 = 4.5 nM PMID: 22503460
CHEMBL202240 agonist Compound 10b IC50 = 0.213 µM EC50 = 2.160 µM PMID: 16451087
CHEMBL202246 agonist Compound 10l IC50 = 2.024 µM EC50 = 3.870 µM PMID: 16451087
PPAR_alpha
CHEMBL2022743 agonist Compound 2 EC50 = 61 nM PMID: 22503460
CHEMBL2022744 agonist Compound 23a EC50 = 2.6 nM PMID: 22503460
CHEMBL2022745 agonist Compound 8a EC50 = 1.5 nM PMID: 22503460
CHEMBL2022746 agonist Compound 8b EC50 = 6.9 nM PMID: 22503460
CHEMBL2022747 agonist Compound 23d EC50 = 3.4 nM PMID: 22503460
CHEMBL2022748 agonist Compound 8c EC50 = 11 nM PMID: 22503460
CHEMBL2024604 agonist Compound 8d EC50 = 32 nM PMID: 22503460
CHEMBL2024605 agonist Compound 8e EC50 = 8.6 nM PMID: 22503460
CHEMBL2024606 agonist Compound 8f EC50 = 15 nM PMID: 22503460
CHEMBL2024607 agonist Compound 8h EC50 = 2.3 nM PMID: 22503460
CHEMBL2024609 agonist Compound 27 EC50 = 5.5  nM PMID: 22503460
CHEMBL2024610 agonist Compound 23c EC50 = 6.7 nM PMID: 22503460
CHEMBL2024611 agonist Compound 17 EC50 = 10 nM PMID: 22503460
CHEMBL2024612 agonist Compound 13a EC50 = 94 nM PMID: 22503460
CHEMBL2024615 agonist Compound 13d EC50 = 190 nM PMID: 22503460
CHEMBL2024618 agonist Compound 8i EC50 = 26 nM PMID: 22503460
CHEMBL2024619 agonist Compound 8j EC50 = 6.2 nM PMID: 22503460
CHEMBL202617 agonist Compound 10h IC50 = 0.629 µM EC50 = 1.630 µM PMID: 16451087
PPAR_alpha
CHEMBL2031856 agonist APH2 IC50 = 0.63 µM EC50 = 14 µM PMID: 22579420
CHEMBL2031858 agonist APH4 IC50 = 0.53 µM EC50 = 5 µM PMID: 22579420
CHEMBL2031860 agonist APH6 IC50 = 2.32 µM EC50 = 11 µM PMID: 22579420
CHEMBL2031952 agonist APH7 IC50 = 0.90 µM EC50 = 7 µM PMID: 22579420
CHEMBL2031955 agonist APH10 IC50 = 0.11 µM EC50 = 8 µM PMID: 22579420
CHEMBL2031956 agonist APH11 IC50 = 0.65 µM EC50 = 5 µM PMID: 22579420
CHEMBL2031957 agonist APH12 IC50 = 1.01 µM EC50 = 6 µM PMID: 22579420
CHEMBL2036277 agonist Compound 1 EC50 = 1.15 µM PMID: 22424300
CHEMBL2036278 agonist Compound 2 EC50 = 11.05 µM PMID: 22424300
CHEMBL2057869 agonist Compound 6 Fluorescence ratio = 0.4 Luciferase expression ~ 400 PMID: 22819190
CHEMBL2057870 agonist Compound 7 Fluorescence ratio = 0.4 Luciferase expression ~ 400 PMID: 22819190
CHEMBL2064741 agonist MDG548 EC50 = 0.467 +/- 0.139 µM PMID: 18155554
CHEMBL2064743 agonist MDG582 EC50 = 0.594 +/- 0.059 µM PMID: 22582973 PPAR_beta
CHEMBL208601 agonist Compound 9a EC50 = 0.015 µM PMID: 16821769
CHEMBL209364 agonist Compound 9b EC50 = 10 µM PMID: 16821769
CHEMBL210162 agonist Compound 14c EC50 = 0.05 µM PMID: 16854085
CHEMBL211237 agonist Compound 18b EC50 = 12.30 µM PMID: 16821769
CHEMBL211597 agonist Compound 10 EC50 = 28.00 µM PMID: 16821769
CHEMBL211674 agonist Compound 5d EC50 = 2.5 µM PMID: 16854085
CHEMBL211807 agonist Compound 10a EC50 = 11.05 µM PMID: 16821769
CHEMBL212023 agonist Compound 12 IC50 = 417+/- 0 nM EC50 = 968 +/- 128 nM PMID: 16970391 PPAR_beta
CHEMBL213547 agonist Compound 5a EC50 = 0.3 µM PMID: 16854085
CHEMBL215127 agonist Compound 11 IC50 = 18 +/- 0 nM EC50 = 46 +/- 3 nM PMID: 16970391
PPAR_alpha
CHEMBL215582 agonist Compound 7 IC50 = 6 +/- 0 nM EC50 = 6 +/- 0 nM PMID: 16970391
PPAR_alpha
CHEMBL221388 agonist Compound 16 Ki = 0.093 µM EC50 = 0.105 µM PMID: 16979341
CHEMBL221438 agonist Compound 18 Ki = 0.02 µM EC50 = 0.005 µM PMID: 16979341
CHEMBL221489 agonist Compound 19 Ki = 0.043 µM EC50 = 0.012 µM PMID: 16979341
CHEMBL221490 agonist Compound 20 Ki = 0.16 µM EC50 = 0.156 µM PMID: 16979341
CHEMBL221529 agonist Compound 15 Ki = 1.1 µM EC50 = 0.887 µM PMID: 16979341
CHEMBL222121 agonist Compound 12 Ki = 1.6 µM EC50 = 0.335 µM PMID: 16979341
CHEMBL223249 agonist Compound 7d Kd = 6.86 µM RU = 7.342 µM PMID: 17010604
CHEMBL229525 agonist Compound 10f EC50 = 1000 nM PMID: 17532641
PPAR_alpha
CHEMBL229573 agonist Compound 10g EC50 = 1000 +/- 170 nM PMID: 17532641
PPAR_alpha
CHEMBL229778 agonist Compound 5c EC50 = 1300 +/- 100 nM PMID: 17532641
PPAR_alpha
CHEMBL229786 agonist Compound 10c EC50 = 3600 +/- 600 nM PMID: 17532641
PPAR_alpha
CHEMBL229831 agonist Compound 5e EC50 = 2300 +/- 200 nM PMID: 17532641
PPAR_alpha
CHEMBL229836 agonist Compound 5i EC50 = 1400 +/- 200 nM PMID: 17532641 PPAR_alpha
CHEMBL229837 agonist Compound 10e EC50 = 1500 +/- 100 nM PMID: 17532641
PPAR_alpha
CHEMBL230305 agonist Compound 11k EC50 = 4 nM PMID: 17157019 PPAR_alpha
CHEMBL230409 agonist Compound 11m EC50 = 6.8 nM PMID: 17157019 PPAR_alpha
CHEMBL230410 agonist Compound 11o EC50 = 7.7 nM PMID: 17157019 PPAR_alpha
CHEMBL230411 agonist Compound 11p EC50 = 3.0 nM PMID: 17157019 PPAR_alpha
CHEMBL230517 agonist Compound 11q EC50 = 2.1 nM PMID: 17157019 PPAR_alpha
CHEMBL230518 agonist Compound 11r EC50 = 2.9 nM PMID: 17157019 PPAR_alpha
CHEMBL230519 agonist Compound 11t EC50 = 5 nM PMID: 17157019 PPAR_alpha
CHEMBL230622 agonist Compound 11u EC50 = 20 nM PMID: 17157019 PPAR_alpha
CHEMBL230623 agonist Compound 11v EC50 = 5.2 nM PMID: 17157019 PPAR_alpha
CHEMBL230705 agonist Compound 11e EC50 = 0.19 nM PMID: 17157019 PPAR_alpha
CHEMBL230706 agonist Compound 11f EC50 = 0.36 nM PMID: 17157019 PPAR_alpha
CHEMBL230707 agonist Compound 11g EC50 = 0.31 nM PMID: 17157019 PPAR_alpha
CHEMBL230814 agonist Compound 11h EC50 = 0.1 nM PMID: 17157019 PPAR_alpha
CHEMBL231425 agonist Compound 11a EC50 = 2.1 nM PMID: 17157019 PPAR_alpha
CHEMBL231523 agonist Compound 11c EC50 = 0.55 nM PMID: 17157019 PPAR_alpha
CHEMBL232798 agonist Compound 14 EC50 = 1.40 µM PMID: 17507225 PPAR_alpha
CHEMBL232799 agonist Compound 18 EC50 = 7.17 µM PMID: 17507225 PPAR_alpha
CHEMBL233003 agonist Compound (S)-9c EC50 = 0.49 µM PMID: 17507225 PPAR_alpha
CHEMBL233785 agonist Compound 9e EC50 = 5.39 µM PMID: 17507225 PPAR_alpha
CHEMBL234819 agonist Compound (S)-9a EC50 = 0.58 µM PMID: 17507225 PPAR_alpha
CHEMBL234820 agonist Compound (R)-9c EC50 = 1.05 µM PMID: 17507225 PPAR_alpha
CHEMBL234858 agonist Compound 9g EC50 = 3.60 µM PMID: 17507225 PPAR_alpha
CHEMBL234859 agonist Compound 9h EC50 = 1.06 µM PMID: 17507225 PPAR_alpha
CHEMBL234908 agonist Compound 6q EC50 = 6.6 µM PMID: 17553681
PPAR_alpha
CHEMBL245464 agonist Compound 30 EC50 = 0.40 µM PMID: 17553678
PPAR_alpha
CHEMBL246070 agonist Compound 40 EC50 = 0.21 µM PMID: 17553678
PPAR_alpha
CHEMBL246281 agonist Compound 42 EC50 = 0.75 µM PMID: 17553678
PPAR_alpha
CHEMBL246282 agonist Compound 43 EC50 = 2.1 µM PMID: 17553678
PPAR_alpha
CHEMBL246510 agonist Compound 45 EC50 = 1.4 µM PMID: 17553678
PPAR_alpha
CHEMBL248324 agonist Compound 23 EC50 = 1.2 µM PMID: 17553678
PPAR_alpha
CHEMBL248326 agonist Compound 25 EC50 = 1.8 µM PMID: 17553678
PPAR_alpha
CHEMBL248526 agonist Compound 26 EC50 = 1.5 µM PMID: 17553678
PPAR_alpha
CHEMBL248527 agonist Compound 28 EC50 = 1.1 µM PMID: 17553678
PPAR_alpha
CHEMBL248660 agonist Compound 15b EC50 = 0.08 µM PMID: 17624777
CHEMBL248663 agonist Compound 9h EC50 = 0.015 µM PMID: 17624777
CHEMBL248848 agonist Compound 15d EC50 = 0.05 µM PMID: 17624777
CHEMBL249045 agonist Compound 15f EC50 = 0.66 µM PMID: 17624777
CHEMBL249239 agonist Compound 15g EC50 = 0.3 µM PMID: 17624777
CHEMBL249438 agonist Compound 9b EC50 = 0.84 µM PMID: 17624777
CHEMBL249439 agonist Compound 9c EC50 = 0.05 µM PMID: 17624777
CHEMBL249442 agonist Compound 15i EC50 = 0.07 µM PMID: 17624777
CHEMBL249833 agonist Compound 15a EC50 = 0.08 µM PMID: 17624777
CHEMBL250223 agonist Compound 3a EC50 = 0.3 µM PMID: 17624777
CHEMBL250276 agonist Compound 15k EC50 = 0.025 µM PMID: 17624777
CHEMBL250277 agonist Compound 15n EC50 = 0.15 µM PMID: 17624777
CHEMBL250278 agonist Compound 16 EC50 = 0.040 µM PMID: 17624777
CHEMBL250647 agonist Compound 15j EC50 = 0.14 µM PMID: 17624777
CHEMBL253417 agonist Compound 36 Ki = 89 nM EC50 = 65 nM PMID: 18255290
CHEMBL253851 agonist Compound 29 Ki = 618 nM EC50 = 48 nM PMID: 18255290
CHEMBL254054 agonist Compound 31 Ki = 10000 nM EC50 = 14 nM PMID: 18255290
CHEMBL255097 agonist Compound 32a IC50 = 3.089 µM EC50 = 0.49 µM PMID: 18511276
CHEMBL255388 agonist Compound 45 IC50 = 0.36 +/- 0.05 µM EC50 = 0.13 +/- 0.002 µM PMID: 18291645 PPAR_alpha
CHEMBL255389 agonist Compound 35 IC50 = 0.04 µM EC50 = 0.12 µM PMID: 18291645 PPAR_alpha
CHEMBL255392 agonist Compound 10b EC50 = 9400 nM PMID: 18162399
PPAR_alpha
CHEMBL255426 agonist Compound 10l EC50 = 620 nM PMID: 18162399
PPAR_alpha
CHEMBL255872 agonist Compound 33b IC50 = 0.287 µM EC50 = 0.014 µM PMID: 18511276 PPAR_alpha
CHEMBL256013 agonist Compound 21d EC50 = 3 µM PMID: 18280733
CHEMBL256142 agonist Compound 33d IC50 = 0.088 µM EC50 = 0.008 µM PMID: 18511276 PPAR_alpha
CHEMBL256358 agonist Compound 33a IC50 = 0.13 µM EC50 = 0.009 µM PMID: 18511276 PPAR_alpha
CHEMBL256468 agonist Compound 37 IC50 = 0.11 +/- 0.024 µM EC50 = 0.004 +/- 0.0 µM PMID: 18291645 PPAR_alpha
CHEMBL257164 agonist Compound 22a IC50 = 0.45 µM EC50 = 0.263 µM PMID: 18511276 PPAR_alpha
CHEMBL257165 agonist Compound 25a IC50 = 1.25 µM EC50 = 0.257 µM PMID: 18511276 PPAR_alpha
CHEMBL257517 agonist Compound 41 IC50 = 0.22 +/- 0.02 µM EC50 = 0.04 +/- 0.011 µM PMID: 18291645 PPAR_alpha
CHEMBL257891 agonist Compound 18 IC50 = 0.04 +/- 0.003 µM EC50 = 0.84 +/- 0.187 µM PMID: 18291645
CHEMBL258212 agonist Compound 24a IC50 = 6.03 µM EC50 = 1.07 µM PMID: 18511276 PPAR_alpha
CHEMBL262981 agonist Compound 2c EC50 = 40 nM PMID: 11527737 PPAR_alpha
CHEMBL270451 agonist Compound 10i EC50 = 120 nM PMID: 18162399 PPAR_alpha
CHEMBL270587 agonist Compound 10d EC50 = 320 nM PMID: 18162399 PPAR_alpha
CHEMBL270664 agonist Compound 10j EC50 = 50 nM PMID: 18162399 PPAR_alpha
CHEMBL270665 agonist Compound 10h EC50 = 280 nM PMID: 18162399 PPAR_alpha
CHEMBL270801 agonist Compound 10e EC50 = 220 nM PMID: 18162399
PPAR_alpha
CHEMBL271240 agonist Compound 17 IC50 = 0.10 +/- 0.003 µM EC50 = 0.09 +/- 0.021 µM PMID: 18291645 PPAR_alpha
CHEMBL271739 agonist Compound 44 IC50 = 0.18 +/- 0.011 EC50 = 0.03 +/- 0.003 µM PMID: 18291645 PPAR_alpha
CHEMBL271873 agonist Compound 15 EC50 = 10 µM PMID: 18280733
CHEMBL271877 agonist Compound 10c EC50 = 2300 nM PMID: 18162399
PPAR_alpha
CHEMBL272336 agonist Compound 42 IC50 = 0.67 +/- 0.07 µM EC50 = 0.06 +/- 0.008 µM PMID: 18291645 PPAR_alpha
CHEMBL272962 agonist Compound 46 IC50 = 0.23 +/- 0.02 µM EC50 = 0.07 +/- 0.001 µM PMID: 18291645 PPAR_alpha
CHEMBL272963 agonist Compound 36 IC50 = 0.8 +/- 0.02 µM EC50 = 0.41 +/- 0.023 µM PMID: 18291645
CHEMBL280293 agonist Compound 13 IC50 = 0.45 µM EC50 = 0.09 µM PMID: 14505666 PPAR_alpha
CHEMBL298187 agonist Compound 16 IC50 = 0.43 µM EC50 = 0.7 µM PMID: 12729668
CHEMBL300026 agonist Compound 25 IC50 = 0.82 µM EC50 = 0.06 µM PMID: 12729668
CHEMBL300629 agonist Compound 11 IC50 = 0.18 µM EC50 = 0.3 µM PMID: 12729668
CHEMBL301156 agonist Compound 12 IC50 = 3.0 µM EC50 = 1.0 µM PMID: 12729668
CHEMBL305723 agonist Compound 2b EC50 = 2 nM PMID: 11527737
PPAR_alpha
CHEMBL305854 agonist Compound 2d EC50 = 25 nM PMID: 11527737 PPAR_alpha
CHEMBL305934 agonist Compound 27 EC50 = 1.8 µM PMID: 12824034
CHEMBL306757 agonist Compound 22 EC50 = 2.0 µM PMID: 12824034
CHEMBL306956 agonist Compound 24 EC50 = 1.1 µM PMID: 12824034
CHEMBL307728 agonist Compound 1n EC50 = 32 nM PMID: 11527737
PPAR_alpha
CHEMBL308325 agonist Compound 29 EC50 = 1.8 µM PMID: 12824034
CHEMBL309778 agonist Compound 1m EC50 = 100 nM PMID: 11527737
PPAR_alpha
CHEMBL310426 agonist Compound 1f EC50 = 16 nM PMID: 11527737
PPAR_alpha
CHEMBL310695 agonist Compound 20 EC50 = 0.50 µM PMID: 12824034
CHEMBL310962 agonist Compound 1h EC50 = 32 nM PMID: 11527737
PPAR_alpha
CHEMBL311147 agonist Compound 16 EC50 = 0.57 µM PMID: 12824034
CHEMBL311395 agonist Compound 11 EC50 = 1.3 µM PMID: 12824034
CHEMBL311429 agonist Compound 1a EC50 = 79 nM PMID: 11527737
PPAR_alpha
CHEMBL312717 agonist Compound 8a IC50 = 169 +/- 22 nM EC50 = 7 +/- 1 nM PMID: 15115385
CHEMBL312791 agonist Compound 1i EC50 = 25 nM PMID: 11527737
PPAR_alpha
CHEMBL318684 agonist Compound 24 IC50 = 0.064 µM EC50 = 0.047 µM PMID: 12873517
CHEMBL323008 agonist Compound 5 IC50 = 3.0 µM EC50 = 2.5 µM PMID: 15163205
CHEMBL324449 agonist Compound 8 IC50 = 0.75 µM EC50 = 1.0 µM PMID: 15163205 PPAR_alpha
CHEMBL325723 agonist Compound 27 EC50 = 2.8 µM PMID: 12904063
PPAR_alpha
CHEMBL326273 agonist Compound 7 IC50 = 0.98 µM EC50 = 7.3 µM PMID: 15163205 PPAR_alpha
CHEMBL328615 agonist Compound 25 IC50 = 0.056 µM EC50 = 0.027 µM PMID: 12873517
CHEMBL331071 agonist Compound 5 IC50 = 0.019 µM EC50 = 0.167 µM PMID: 14505666
CHEMBL331206 agonist Compound 13 EC50 = 2.5 µM PMID: 12904063 PPAR_alpha
CHEMBL331469 agonist Compound 51 EC50 = 7.4 µM PMID: 12904063 PPAR_alpha
CHEMBL33188 agonist Compound 16 EC50 = 1.12 µM PMID: 15177462
PPAR_alpha
CHEMBL338390 agonist Compound 4a EC50 = 1.7 µM PMID: 10714503
CHEMBL341105 agonist Compound 4c EC50 = 2.8 µM PMID: 10714503
CHEMBL342292 agonist Compound 10 pKi = 8.32 +/- 0.02 pEC50 = 7.91 +/- 0.22 PMID: 9836621
CHEMBL342990 agonist Compound 48 pKi = 7.37 +/- 0.11 pEC50 = 5.39 +/- 0.25 PMID: 9836622
CHEMBL343210 agonist Compound 15 pKi = 9.05 +/- 0.07 pEC50 = 8.82 +/- 0.33 PMID: 9836621 PPAR_alpha
CHEMBL344776 agonist Compound 54 pKi = 5.94 pEC50 = 6.38 +/- 0.07 PMID: 9836622
CHEMBL345541 agonist Compound 46 pKi = 8.01 +/- 0.02 pEC50 = 7.92 +/- 0.02 PMID: 9836622
CHEMBL346219 agonist Compound 16 pKi = 7.30 +/- 0.17 pEC50 = 6.30 +/- 0.05 PMID: 9836620
CHEMBL346415 agonist Compound 8 pKi = 6.10 +/- 0.24 pEC50 = 4.99 +/- 1.13 PMID: 9836620
CHEMBL347076 agonist Compound 34 pKi = 7.31 +/- 0.02 pEC50 = 7.62 +/- 0.04 PMID: 9836622
CHEMBL347788 agonist Compound 55 pKi = 8.49 +/- 0.047 pEC50 = 8.05 +/- 0.07 PMID: 9836622
CHEMBL354863 agonist Compound 3e EC50 = 12.4 +/- 4.8 µM PMID: 11831892
CHEMBL356350 agonist Compound 2 pKi = 7.93 +/- 0.01 pEC50 = 6.64 +/- 0.20 PMID: 9836620
CHEMBL356382 agonist Compound 12 pKi = 8.96 +/- 0.05 pEC50 = 9.22 +/- 0.27 PMID: 9836621 PPAR_alpha
CHEMBL356707 agonist Compound 19 pKi = 7.91 +/- 0.06 pEC50 = 5.52 +/- 0.24 PMID: 9836621
CHEMBL357479 agonist Compound 15 pKi = 6.21 +/- 0.20 pEC50 = 5.94 +/- 0.02 PMID: 9836620
CHEMBL358325 agonist Compound 24 pKi = 8.66 +/- 0.06 pEC50 = 8.89 +/- 0.04 PMID: 9836621
CHEMBL358379 agonist Compound 4 pKi = 8.96 +/- 0.11 pEC50 = 10.00 +/- 0.50 PMID: 9836621 PPAR_alpha
CHEMBL359150 agonist Compound 51 pKi = 7.81 +/- 0.04 pEC50 = 6.39 +/- 0.07 PMID: 9836622
CHEMBL359285 agonist Compound 20 pKi = 8.59 +/- 0.10 pEC50 = 7.51 +/- 0.33 PMID: 9836621
CHEMBL359333 agonist Compound 42 pKi = 7.87 +/- 0.04 pEC50 = 6.64 +/- 0.44 PMID: 9836622
CHEMBL359377 agonist Compound 9 pKi = 6.79 +/- 0.04 pEC50 = 4.78 +/- 0.44 PMID: 9836620
CHEMBL360067 agonist Compound 37 EC50 = 1000 nM PMID: 14695833
CHEMBL360112 agonist Compound 22 EC50 = 2700 nM PMID: 14695833
CHEMBL360230 agonist Compound 42 EC50 = 260 nM PMID: 14695833
CHEMBL360281 agonist Compound 12b Fold induction = 1.7 PMID: 15664804
CHEMBL360730 agonist Compound 35 EC50 = 359 nM PMID: 14695833
CHEMBL361004 agonist Compound 2d Fold induction = 2.3 PMID: 15664804
CHEMBL364748 agonist Compound 1 EC50 = 14.46 +/- 3.46 µM PMID: 18835719 PPAR_alpha
CHEMBL366720 agonist Compound 20 EC50 = 1000 nM PMID: 14695833
CHEMBL367589 agonist Compound 54 EC50 = 380 nM PMID: 14695833
CHEMBL369054 agonist Compound 18 EC50 = 1000 nM PMID: 14695833
CHEMBL369655 agonist Compound 19 EC50 = 79 nM PMID: 14695833
CHEMBL369694 agonist Compound 53 EC50 = 718 nM PMID: 14695833
CHEMBL369930 agonist Compound 48 EC50 = 16 nM PMID: 16275080 PPAR_alpha
CHEMBL370186 agonist Compound 58 EC50 = 32 nM PMID: 16275080 PPAR_alpha
CHEMBL370407 agonist Compound 8 EC50 = 9560 nM PMID: 16275080 PPAR_alpha
CHEMBL370809 agonist Compound 10 EC50 = 68 nM PMID: 16275080 PPAR_alpha
CHEMBL371041 agonist Compound 69 EC50 = 16 nM PMID: 16275080 PPAR_alpha
CHEMBL371760 agonist Compound 64 EC50 = 368 nM PMID: 16275080 PPAR_alpha
CHEMBL371764 agonist Compound 40 EC50= 104 nM PMID: 16275080 PPAR_alpha
CHEMBL372519 agonist Compound 5 EC50 = 160 nM PMID: 16275080
CHEMBL372825 agonist Compound 13 EC50 = 85 nM PMID: 16275080
CHEMBL373007 agonist Compound 13 PMID: 16290140
CHEMBL373318 agonist Compound 14b EC50 = 549 nM PMID: 16137885 PPAR_alpha
CHEMBL373430 agonist Compound 9 Ki = 0.073 µM EC50 = 0.129 µM PMID: 16979341
CHEMBL375370 agonist Compound 17 Ki = 0.3 µM EC50 = 0.130 µM PMID: 16979341
CHEMBL376165 agonist Compound 5h EC50 = 650 +/- 10 nM PMID: 17532641
PPAR_alpha
CHEMBL378399 agonist Compound 10 EC50 = 0.3 µM PMID: 16854085
CHEMBL379439 agonist Compound 14a EC50 = 0.22 µM PMID: 16854085
CHEMBL380961 agonist Compound 59 EC50 = 247 nM PMID: 16275080 PPAR_alpha
CHEMBL381470 agonist Compound 12 PMID: 16290140
CHEMBL381891 agonist Compound 37 EC50 = 330 nM PMID: 16275080 PPAR_alpha
CHEMBL382718 agonist Compound 68 EC50 = 113 nM PMID: 16275080 PPAR_alpha
CHEMBL382928 agonist Compound 7 EC50 = 3180 nM PMID: 16275080
CHEMBL382957 agonist Compound 47 EC50 = 22 nM PMID: 16275080 PPAR_alpha
CHEMBL382982 agonist Compound 67 EC50 = 43 nM PMID: 16275080 PPAR_alpha
CHEMBL383362 agonist Compound 15 PMID: 16290140
CHEMBL383398 agonist Compound 55 EC50 = 206 nM PMID: 16275080 PPAR_alpha
CHEMBL383789 agonist Compound 53 EC50 = 61 nM PMID: 16275080 PPAR_alpha
CHEMBL385106 agonist Compound 8 Ki = 0.348 µM EC50 = 0.280 µM PMID: 16979341
CHEMBL385974 agonist Compound 21 Ki = 2.3 µM EC50 = 2.50 µM PMID: 16979341
CHEMBL387588 agonist Compound 11s EC50 = 48 nM PMID: 17157019 PPAR_alpha
CHEMBL387914 agonist Compound 5g EC50 = 2200 +/- 500 nM PMID: 17532641
PPAR_alpha
CHEMBL388008 agonist Compound 11n EC50 = 28 nM PMID: 17157019 PPAR_alpha
CHEMBL388422 agonist Compound 11b EC50 = 1.0 nM PMID: 17157019 PPAR_alpha
CHEMBL388645 agonist Compound 11d EC50 = 0.3 nM PMID: 17157019 PPAR_alpha
CHEMBL389297 agonist Compound 11i EC50 = 0.54 nM PMID: 17157019 PPAR_alpha
CHEMBL389298 agonist Compound 11l EC50 = 13 nM PMID: 17157019 PPAR_alpha
CHEMBL389903 agonist Compound 5d EC50 = 1300 +/- 100 nM PMID: 17532641
PPAR_alpha
CHEMBL390116 agonist Compound 10d EC50 = 2400 +/- 100 nM PMID: 17532641
PPAR_alpha
CHEMBL391620 agonist Compound 44 EC50 = 1.8 µM PMID: 17553678
PPAR_alpha
CHEMBL392810 agonist Compound 33 EC50 = 2.0 µM PMID: 17553678
PPAR_alpha
CHEMBL393005 agonist Compound 11 EC50 = 1.42 µM PMID: 17507225 PPAR_alpha
CHEMBL393381 agonist Compound (R)-9d EC50 = 0.14 µM PMID: 17507225 PPAR_alpha
CHEMBL394031 agonist Compound (R)-9a EC50 = 0.35 µM PMID: 17507225 PPAR_alpha
CHEMBL396109 agonist Compound 10 EC50 = 0.30 µM PMID: 17507225 PPAR_alpha
CHEMBL398117 agonist Compound 27 EC50 = 1.0 µM PMID: 17553678
PPAR_alpha
CHEMBL398118 agonist Compound 29 EC50 = 0.53 µM PMID: 17553678
PPAR_alpha
CHEMBL398424 agonist Compound 15l EC50 = 0.20 µM PMID: 17624777
CHEMBL398677 agonist Compound 34 Ki = 48 nM EC50 = 11 nM PMID: 18255290
CHEMBL398804 agonist Compound (S)-9d EC50 = 0.16 µM PMID: 17507225 PPAR_alpha
CHEMBL399629 agonist Compound 30 Ki = 10000 nM EC50 = 19 nM PMID: 18255290
CHEMBL399661 agonist Compound 15m EC50 = 0.02 µM PMID: 17624777
CHEMBL399847 agonist Compound 9j EC50 = 0.03 µM PMID: 17624777
CHEMBL400351 agonist Compound 9a EC50 = 0.2 µM PMID: 17624777
CHEMBL400955 agonist Compound 9d EC50 = 0.2 µM PMID: 17624777
CHEMBL400956 agonist Compound 9e EC50 = 0.15 µM PMID: 17624777
CHEMBL400989 agonist Compound 15c EC50 = 0.19 µM PMID: 17624777
CHEMBL401015 agonist Compound 9b EC50 = 4.58 µM PMID: 17507225 PPAR_alpha
CHEMBL401092 agonist Compound 5 EC50 = 1.5 µM PMID: 17624777
CHEMBL401388 agonist Compound 15h EC50 = 0.25 µM PMID: 17624777
CHEMBL401534 agonist Compound 33c IC50 = 0.133 µM EC50 = 0.024 µM PMID: 18511276 PPAR_alpha
CHEMBL401616 agonist Compound 4b EC50 = 100 µM PMID: 18280733
CHEMBL401712 agonist Compound 12b EC50 = 30 µM PMID: 18280733
CHEMBL401841 agonist Compound 9g EC50 = 0.03 µM PMID: 17624777
CHEMBL402161 agonist Compound 10f EC50 = 120 nM PMID: 18162399
PPAR_alpha
CHEMBL403847 agonist Compound 43 IC50 = 0.16 +/- 0.02 µM EC50 = 0.18 +/- 0.048 µM PMID: 18291645 PPAR_alpha
CHEMBL404004 agonist Compound 9i EC50 = 0.09 µM PMID: 17624777
CHEMBL404439 agonist Compound 21c EC50 = 1 µM PMID: 18280733
CHEMBL404451 agonist Compound 38 IC50 = 4.24 +/- 0.14 µM EC50 = 0.50 +/- 0.048 µM PMID: 18291645
CHEMBL404646 agonist Compound 39 IC50 = 0.11 +/- 0.01 µM EC50 = 0.04 +/- 0.005 µM PMID: 18291645 PPAR_alpha
CHEMBL411118 agonist Compound 19 IC50 = 3.4 +/- 0.31 µM EC50 = 0.02 +/- 0.002 µM PMID: 18291645 PPAR_alpha
CHEMBL414836 agonist Compound 2e EC50 = 2200 nM PMID: 21557540
CHEMBL419756 agonist Compound 15 IC50 = 0.37 µM EC50 = 0.83 µM PMID: 15163205 PPAR_alpha
CHEMBL420441 agonist Compound 20 IC50 = 0.073 µM EC50 = 0.165 µM PMID: 12873517
CHEMBL421781 agonist Compound 44 pKi = 7.63 +/- 0.04 pEC50 = 7.42 +/- 0.54 PMID: 9836622
CHEMBL423026 agonist Compound 19 pKi = 8.58 +/- 0.39 pEC50 = 8.36 +/- 0.41 PMID: 9836620
CHEMBL425605 agonist Compound 14b EC50 = 0.21 µM PMID: 16854085
CHEMBL425666 agonist Compound 5b EC50 = 1800 +/- 900 nM PMID: 17532641
PPAR_alpha
CHEMBL425766 agonist Compound 10e IC50 = 0.129 µM EC50 = 0.160 µM PMID: 16451087
PPAR_alpha
CHEMBL426371 agonist Compound 5f EC50 = 6200 +/- 1500 nM PMID: 17532641 PPAR_beta
CHEMBL427140 agonist Compound 2a Fold induction = 13.4 PMID: 15664804
CHEMBL427701 agonist Compound 41 EC50 = 0.13 µM PMID: 17553678
PPAR_alpha
CHEMBL428019 agonist Compound 9f EC50 = 3.48 µM PMID: 17507225 PPAR_alpha
CHEMBL428574 agonist Compound 32 EC50 = 1.6 µM PMID: 17553678
PPAR_alpha
CHEMBL429661 agonist Compound 9f EC50 = 0.07 µM PMID: 17624777
CHEMBL429734 agonist Compound 40 IC50 = 0.25 +/- 0.05 µM EC50 = 0.10 +/- 0.033 µM PMID: 18291645 PPAR_alpha
CHEMBL429824 agonist Compound 37 EC50 = 1.8 µM PMID: 17553678
PPAR_alpha
CHEMBL430970 agonist Compound 24 IC50 = 0.13 µM EC50 = 0.02 µM PMID: 12729668
CHEMBL431450 agonist Compound 6 IC50 = 2.3 µM EC50 = 1.2 µM PMID: 15163205
CHEMBL432747 agonist Compound 4i Ki = 18 nM EC50 = 280 nM PMID: 22582973
CHEMBL433306 agonist Compound 1d EC50 = 100 nM PMID: 11527737
PPAR_alpha
CHEMBL433316 agonist Compound 2g EC50 = 160 nM PMID: 11527737
PPAR_alpha
CHEMBL434063 agonist Compound 18 pKi = 8.04 +/- 0.33 pEC50 = 7.74 +/- 0.29 PMID: 9836620
CHEMBL434945 agonist Compound 1 EC50 = 104 nM PMID: 16275080 PPAR_alpha
CHEMBL435688 agonist Compound 3 Fold induction = 1.4 PMID: 15664804
CHEMBL436113 agonist Compound 12 EC50 = 12 nM PMID: 16275080 PPAR_alpha
CHEMBL438979 agonist Compound 43 EC50 = 153 nM PMID: 16275080 PPAR_alpha
CHEMBL440375 agonist Compound 39 EC50 = 200 nM PMID: 14695833
CHEMBL440758 agonist Compound 57 EC50 = 205 nM PMID: 16275080 PPAR_alpha
CHEMBL442909 agonist Compound 13 EC50 = 9.25 +/- 1.48 µM PMID: 18835719 PPAR_alpha
CHEMBL443051 agonist Compound 5c EC50 = 1.0 µM PMID: 16854085
CHEMBL443910 agonist Compound 8h EC50 = 0.001 µM PMID: 18329751 PPAR_alpha
CHEMBL445942 agonist Compound 32b IC50 = 7.692 µM EC50 = 1.29 µM PMID: 18511276 PPAR_alpha
CHEMBL446177 agonist Compound 9 Fold induction = 6.0 PMID: 15664804
CHEMBL446629 agonist Compound 7 pKi = 9.16 +/- 0.04 pEC50 = 8.03 +/- 0.55 PMID: 9836621
CHEMBL447533 agonist Compound 14 EC50 = 10 µM PMID: 18280733
CHEMBL448790 agonist Compound 17b EC50 = 18.49 µM PMID: 16821769
CHEMBL449099 agonist Compound 23 EC50 = 2.81 +/- 0.44 µM PMID: 18835719 PPAR_alpha
CHEMBL451321 agonist Compound 20 EC50 = 10 +/- 1.0 µM PMID: 22341573
CHEMBL455853 agonist Compound 8a EC50 = 1.12 µM PMID: 18329751 PPAR_alpha
CHEMBL455936 agonist Compound 3 EC50 = 6.2 +/- 0.3 µM PMID: 20307981
CHEMBL456752 agonist Compound 4f EC50 = 140 +/- 20 nM PMID: 18662876
PPAR_alpha
CHEMBL456753 agonist Compound 4g EC50 = 190 +/- 30 nM PMID: 18662876
PPAR_alpha
CHEMBL456912 agonist Compound 7e EC50 = 0.001 µM PMID: 18329751 PPAR_alpha
CHEMBL456973 agonist Compound 4h EC50 = 36 +/- 6 nM PMID: 18662876
PPAR_alpha
CHEMBL456974 agonist Compound 4i EC50 =24 +/- 2 nM PMID: 18662876
PPAR_alpha
CHEMBL457405 agonist Compound 4k EC50 = 15 +/- 2 nM PMID: 18662876
PPAR_alpha
CHEMBL458221 agonist Compound 7d EC50 = 1.74 µM PMID: 18329751 PPAR_alpha
CHEMBL458648 agonist Compound 7b EC50 = 0.001 µM PMID: 18329751 PPAR_alpha
CHEMBL458866 agonist Compound 8b EC50 = 0.001 µM PMID: 18329751 PPAR_alpha
CHEMBL458867 agonist Compound 7c EC50 = 0.35 µM PMID: 18329751 PPAR_alpha
CHEMBL462982 agonist Compound 4d EC50 = 1100 +/- 100 nM PMID: 18662876
PPAR_alpha
CHEMBL469937 agonist Compound 24 EC50 = 0.35 +/- 0.21 µM PMID: 18835719 PPAR_alpha
CHEMBL470144 agonist Compound 25 EC50 = 0.45 +/- 0.02 µM PMID: 18835719
CHEMBL470145 agonist Compound 26 EC50 = 0.24 +/- 0.16 µM PMID: 18835719 PPAR_alpha
CHEMBL471191 agonist Compound 21 EC50 = 2.23 +/- 0.23 µM PMID: 18835719 PPAR_alpha
CHEMBL471814 agonist Compound 18 EC50 = 1.14 +/- 0.65 µM PMID: 18835719
CHEMBL471851 agonist Compound 17 EC50 = 2.49 +/- 0.13 µM PMID: 18835719 PPAR_alpha
CHEMBL473952 agonist Compound 2a IC50 = 0.14 µM EC50 = 0.14 µM PMID: 19201606 PPAR_alpha
CHEMBL473953 agonist Compound 2e IC50 = 1.67 µM EC50 = 1.67 µM PMID: 19201606
CHEMBL473961 agonist Compound 1a IC50 = 1.67 µM EC50 = 2.37 µM PMID: 19201606 PPAR_alpha
CHEMBL474148 agonist Compound 2b IC50 = 4.74 µM EC50 = 4.74 µM PMID: 19201606
CHEMBL474149 agonist Compound 2c IC50 = 0.07 µM EC50 = 0.07 µM PMID: 19201606 PPAR_alpha
CHEMBL474157 agonist Compound 1b IC50 = 0.16 µM EC50 = 0.55 µM PMID: 19201606 PPAR_alpha
CHEMBL474158 agonist Compound 1c IC50 = 3.82 µM EC50 = 1.57 µM PMID: 19201606
CHEMBL474548 agonist Compound 3c IC50 = 1.48 µM EC50 = 9.27 µM PMID: 19201606
CHEMBL474550 agonist Compound 4c IC50 = 0.88 µM EC50 = 5.80 µM PMID: 19201606
CHEMBL474551 agonist Compound 3d IC50 = 0.67 µM EC50 = 2.19 µM PMID: 19201606
CHEMBL474947 agonist Compound 4a IC50 = 0.712 µM EC50 = 9.27 µM PMID: 19201606 PPAR_alpha
CHEMBL475916 agonist Compound 5c EC50 = 1.67 µM PMID: 18771917 PPAR_alpha
CHEMBL475988 agonist Compound 8f EC50 = 0.001 µM PMID: 18329751 PPAR_alpha
CHEMBL475989 agonist Compound 7g EC50 = 0.42 µM PMID: 18329751 PPAR_alpha
CHEMBL476197 agonist Compound 8g EC50 = 0.16 µM PMID: 18329751 PPAR_alpha
CHEMBL476896 agonist Compound 30 IC50 = 2.2 µM EC50 = 2.5 µM PMID: 18394907
CHEMBL476897 agonist Compound 31 IC50 = 2.8 µM EC50 = 13 µM PMID: 18394907
CHEMBL477298 agonist Compound 57 IC50 = 2.8 µM EC50 = 4 µM PMID: 18394907
CHEMBL477318 agonist Compound 58 IC50 = 4 µM EC50 = 3.9 µM PMID: 18394907
CHEMBL477644 agonist Compound 8i EC50 = 0.17 µM PMID: 18329751 PPAR_alpha
CHEMBL477801 agonist Compound 5g EC50 = 2.23 µM PMID: 18771917 PPAR_alpha
CHEMBL477940 agonist Compound 32 IC50 = 53 µM EC50 = 9 µM PMID: 18394907
CHEMBL478335 agonist Compound 56 IC50 = 0.587 µM EC50 = 1.8 µM PMID: 18394907
CHEMBL478675 agonist Compound 5a EC50 = 2.15 µM PMID: 18771917 PPAR_alpha
CHEMBL478726 agonist Compound 29 IC50 = 26 µM EC50 = 4.5 µM PMID: 18394907
CHEMBL478897 agonist Compound 7j EC50 = 3.55 µM PMID: 18329751
CHEMBL482740 agonist Compound Rac-2Ea IC50 = 0.002 µM EC50 = 0.004 µM PMID: 19349176 PPAR_alpha
CHEMBL482827 agonist Compound 64 EC50 = 0.606 µM PMID: 18826205 PPAR_alpha
CHEMBL483032 agonist Compound 61 EC50 = 1.16 µM PMID: 18826205 PPAR_alpha
CHEMBL483035 agonist Compound 66 EC50 = 28.1 µM PMID: 18826205 PPAR_alpha
CHEMBL483341 agonist Compound Rac-2Da IC50 = 0.003 µM EC50 = 0.004 µM PMID: 19349176 PPAR_alpha
CHEMBL483351 agonist Compound Rac-3Ah IC50 = 0.802 µM EC50 = 0.716 µM PMID: 19349176 PPAR_alpha
CHEMBL484462 agonist Compound 63 EC50 = 0.740 µM PMID: 18826205 PPAR_alpha
CHEMBL485291 agonist Compound 68 EC50 = 2.73 µM PMID: 18826205 PPAR_alpha
CHEMBL486205 agonist Compound 3 EC50 = 1.65 +/- 0.21 µM PMID: 18835719
CHEMBL486357 agonist Compound 11 EC50 = 2.18 /- 0.66 µM PMID: 18835719 PPAR_alpha
CHEMBL486363 agonist Compound 10 EC50 = 4.49 +/- 1.29 µM PMID: 18835719 PPAR_alpha
CHEMBL486364 agonist Compound 12 EC50 = 2.25 /- 0.30 µM PMID: 18835719 PPAR_alpha
CHEMBL486365 agonist Compound 14 EC50 = 1.43 +/- 0.10 µM PMID: 18835719 PPAR_alpha
CHEMBL489171 agonist Compound 5n EC50 = 0.174 µM PMID: 18771917 PPAR_alpha
CHEMBL489172 agonist Compound 5p EC50 = 0.706 µM PMID: 18771917 PPAR_alpha
CHEMBL489363 agonist Compound 5i EC50 = 3.72 µM PMID: 18771917 PPAR_alpha
CHEMBL489364 agonist Compound 5j EC50 = 0.396 µM PMID: 18771917 PPAR_alpha
CHEMBL489377 agonist Compound 5s EC50 = 1.42 µM PMID: 18771917 PPAR_alpha
CHEMBL489506 agonist Compound 4d IC50 = 1.35 µM EC50 = 7.33 µM PMID: 19201606
CHEMBL489507 agonist Compound 4e IC50 = 0.517 µM EC50 = 3.86 µM PMID: 19201606
CHEMBL489563 agonist Compound 5k EC50 = 2.38 µM PMID: 18771917 PPAR_alpha
CHEMBL489591 agonist Compound 5y EC50 = 0.504 µM PMID: 18771917 PPAR_alpha
CHEMBL489768 agonist Compound 13c EC50 = 22.83 µM PMID: 18771917 PPAR_alpha
CHEMBL489769 agonist Compound 13d EC50 = 18.76 µM PMID: 18771917 PPAR_alpha
CHEMBL490395 agonist Compound 5m EC50 = 0.689 µM PMID: 18771917 PPAR_alpha
CHEMBL490401 agonist Compound 5q EC50 = 1.44 µM PMID: 18771917 PPAR_alpha
CHEMBL491142 agonist Compound 4f IC50 = 0.007 µM EC50 = 0.013 µM PMID: 19201606
CHEMBL491423 agonist Compound 5u EC50 = 3.30 µM PMID: 18771917 PPAR_alpha
CHEMBL491596 agonist Compound 13a EC50 = 5.29 µM PMID: 18771917 PPAR_alpha
CHEMBL491597 agonist Compound 13b EC50 = 4.88 µM PMID: 18771917 PPAR_alpha
CHEMBL491606 agonist Compound 5l EC50 = 3.93 µM PMID: 18771917 PPAR_alpha
CHEMBL491622 agonist Compound 5v EC50 = 12.6 µM PMID: 18771917 PPAR_alpha
CHEMBL491623 agonist Compound 5x EC50 = 2.32 µM PMID: 18771917 PPAR_alpha
CHEMBL491750 agonist Compound 3e IC50 = 0.034 µM EC50 = 0.56 µM PMID: 19201606
CHEMBL491751 agonist Compound 3f IC50 = 0.005 µM EC50 = 0.004 µM PMID: 19201606
CHEMBL492031 agonist Compound 5t EC50 = 2.30 µM PMID: 18771917 PPAR_alpha
CHEMBL492046 agonist Compound 71 EC50 = 25.4 µM PMID: 18826205
CHEMBL496268 agonist chlorophellin C PMID: 18667308
CHEMBL496453 agonist chlorophellin A PMID: 18667308
CHEMBL50143 agonist Compound 19 IC50 = 0.12 µM EC50 = 0.2 µM PMID: 12729668
CHEMBL50752 agonist Compound 13 IC50 = 0.48 µM EC50 = 0.3 µM PMID: 12729668
CHEMBL50755 agonist Compound 18 IC50 = 1.0 µM EC50 = 0.4 µM PMID: 12729668
CHEMBL508225 agonist Compound 22 EC50 = 1.10 +/- 0.06 µM PMID: 18835719 PPAR_alpha
CHEMBL50885 agonist Compound 27 IC50 = 0.46 µM EC50 = 0.03 µM PMID: 12729668
CHEMBL508953 agonist Compound 7f Transactiv. = 1.8 PMID: 18805005 PPAR_beta
CHEMBL50984 agonist Compound 30 IC50 = 5.7 µM EC50 = 0.5 µM PMID: 12729668
CHEMBL514007 agonist Compound 2d IC50 = 2.16 µM EC50 = 2.16 µM PMID: 19201606 PPAR_alpha
CHEMBL514173 agonist Compound 3b IC50 = 0.75 µM EC50 = 7.90 µM PMID: 19201606
CHEMBL514174 agonist Compound 4b IC50 = 10 µM EC50 = 13.6 µM PMID: 19201606
CHEMBL514256 agonist Compound 4j EC50 = 17 +/- 2 nM PMID: 18662876
PPAR_alpha
CHEMBL514328 agonist Compound 1d IC50 = 0.89 µM EC50 = 4.20 µM PMID: 19201606 PPAR_alpha
CHEMBL514381 agonist Compound 7i EC50 = 0.96 µM PMID: 18329751 PPAR_alpha
CHEMBL514441 agonist Compound 8c EC50 = 0.1 µM PMID: 18329751 PPAR_alpha
CHEMBL514544 agonist Compound 5h EC50 = 7.56 µM PMID: 18771917 PPAR_alpha
CHEMBL514568 agonist Compound 8d EC50 = 0.25 µM PMID: 18329751 PPAR_alpha
CHEMBL514713 agonist Compound 7h EC50 = 1.62 µM PMID: 18329751 PPAR_alpha
CHEMBL514871 agonist Compound 5d EC50 = 5.83 µM PMID: 18771917 PPAR_alpha
CHEMBL515106 agonist Compound 3a IC50 = 0.069 µM EC50 = 3.79 µM PMID: 19201606 PPAR_alpha
CHEMBL515181 agonist Compound 55 IC50 = 22 µM EC50 = 3.9 µM PMID: 18394907
CHEMBL515454 agonist Compound 7f EC50 = 0.001 µM PMID: 18329751
CHEMBL515666 agonist Compound 8e EC50 = 0.001 µM PMID: 18329751 PPAR_alpha
CHEMBL515991 agonist Compound 7a EC50 = 1.26 µM PMID: 18329751 PPAR_alpha
CHEMBL516274 agonist Compound 5f EC50 = 1.89 µM PMID: 18771917 PPAR_alpha
CHEMBL518038 agonist Compound 2 EC50 = 3.6 +/- 0.2 µM PMID: 20307981
CHEMBL518507 agonist Compound 6 EC50 = 3.7 +/- 1.0 µM PMID: 20503989
CHEMBL519802 agonist Compound Rac-2Ag IC50 = 0.916 µM EC50 = 1.615 µM PMID: 19349176 PPAR_alpha
CHEMBL519857 agonist Compound 67 EC50 = 3.19 µM PMID: 18826205 PPAR_alpha
CHEMBL519974 agonist Compound Rac-3Ca IC50 = 0.007 µM EC50 = 0.016 µM PMID: 19349176 PPAR_alpha
CHEMBL520305 agonist Compound 65 EC50 = 38.6 µM PMID: 18826205
CHEMBL521730 agonist chlorophellin B PMID: 18667308
CHEMBL521925 agonist Compound 60 EC50 = 0.220 µM PMID: 18826205 PPAR_alpha
CHEMBL522754 agonist Compound 5o EC50 = 0.661 µM PMID: 18771917 PPAR_alpha
CHEMBL523649 agonist Compound 5w EC50 = 4.60 µM PMID: 18771917 PPAR_alpha
CHEMBL523650 agonist Compound 62 EC50 = 0.816 µM PMID: 18826205 PPAR_alpha
CHEMBL523944 agonist Compound 5z EC50 = 0.728 µM PMID: 18771917 PPAR_alpha
CHEMBL52426 agonist Compound 26 IC50 = 2.0 µM EC50 = 0.08 µM PMID: 12729668
CHEMBL525772 agonist Compound 2 EC50 = 2.12 +/- 0.59 µM PMID: 18835719
CHEMBL52633 agonist Compound 28 IC50 = 0.25 µM EC50 = 0.12 µM PMID: 12729668
CHEMBL53746 agonist Compound 22 IC50 = 0.13 µM EC50 = 0.03 µM PMID: 12729668
CHEMBL539703 agonist Compound 11i EC50 = 4.79 +/- 0.76 µM PMID: 19574056
CHEMBL540732 agonist Compound 8 IC50 = 0.19 µM PMID: 19719236
CHEMBL54097 agonist Compound 17 IC50 = 6.7 µM EC50 = 0.1 µM PMID: 12729668
CHEMBL541509 agonist Compound 11g EC50 = 6.36 +/- 0.17 µM PMID: 19574056
CHEMBL549351 agonist Compound 7 IC50 = 0.039 µM PMID: 19719236
CHEMBL549723 agonist Compound 7 EC50 = 0.25 +/- 0.05 µM PMID: 19556125 PPAR_alpha
CHEMBL550332 agonist Compound 14 EC50 = 0.049 +/- 0.02 µM PMID: 19556125 PPAR_alpha
CHEMBL550396 agonist Compound 11l EC50 = 4.94 +/- 0.07 µM PMID: 19574056
CHEMBL550762 agonist Compound 1 IC50 = 0.98 µM PMID: 19719236
CHEMBL551420 agonist Compound 20 EC50 = 0.22 +/- 0.04 µM PMID: 19556125 PPAR_alpha
CHEMBL551884 agonist Compound 18 EC50 = 0.39 +/- 0.02 µM PMID: 19556125 PPAR_alpha
CHEMBL552347 agonist Compound 6 EC50 = 0.29 +/- 0.04 µM PMID: 19556125 PPAR_alpha
CHEMBL553668 agonist Compound 11f EC50 = 3.50 +/- 2.18 µM PMID: 19574056
CHEMBL554364 agonist Compound 11h EC50 = 4.46 +/- 2.48 µM PMID: 19574056
CHEMBL554746 agonist Compound 11d EC50 = 5.54 +/- 1.60 µM PMID: 19574056
CHEMBL557042 agonist Compound 11k EC50 = 5.01 +/- 1.02 µM PMID: 19574056
CHEMBL557244 agonist Compound 11m EC50 = 4.47 +/- 1.46 µM PMID: 19574056
CHEMBL557342 agonist Compound 9 EC50 = 0.085 +/- 0.03 µM PMID: 19556125 PPAR_alpha
CHEMBL558072 agonist Compound 12 EC50 = 0.19 +/- 0.04 µM PMID: 19556125 PPAR_alpha
CHEMBL558083 agonist Compound 12i IC50 = 9 nM EC50 = 2 nM PMID: 19530681 PPAR_alpha
CHEMBL559752 agonist Compound 27 EC50 = 4.2 +/- 0.53 µM PMID: 19556125
CHEMBL560205 agonist Compound 13 EC50 = 0.55 +/- 0.03 µM PMID: 19556125 PPAR_alpha
CHEMBL560484 agonist Compound 8 EC50 = 0.09 +/- 0.02 µM PMID: 19556125 PPAR_alpha
CHEMBL560513 agonist Compound 3 IC50 = 0.83 µM PMID: 19719236
CHEMBL561006 agonist Compound 25 EC50 = 15.7 +/- 0.77 µM PMID: 19556125
CHEMBL561284 agonist Compound 15 EC50 = 2.0 +/- 0.43 µM PMID: 19556125 PPAR_alpha
CHEMBL561327 agonist Compound 11n EC50 = 6.13 +/- 0.44 µM PMID: 19574056
CHEMBL561371 agonist Compound 2 IC50 = 1.61 µM PMID: 19719236
CHEMBL561544 agonist Compound 10 EC50 = 0.021 +/- 0.01 µM PMID: 19556125 PPAR_alpha
CHEMBL561776 agonist Compound 5 IC50 = 1.68 µM PMID: 19719236
CHEMBL562786 agonist Compound 21 EC50 = 3.8 +/- 0.34 µM PMID: 19556125
CHEMBL563351 agonist Compound 19 EC50 = 0.11 +/- 0.01 µM PMID: 19556125 PPAR_alpha
CHEMBL563546 agonist Compound 16 EC50 = 0.15 +/- 0.02 µM PMID: 19556125 PPAR_alpha
CHEMBL563824 agonist Compound 11e EC50 = 6.62 +/- 0.41 µM PMID: 19574056
CHEMBL564017 agonist Compound 17 EC50 = 0.025 +/- 0.02 µM PMID: 19556125 PPAR_alpha
CHEMBL564210 agonist Compound 12j IC50 = 5 nM EC50 = 2 nM PMID: 19530681 PPAR_alpha
CHEMBL564368 agonist Compound 4 IC50 = 0.63 µM PMID: 19719236
CHEMBL569372 agonist Compound 6 IC50 = 1.72 µM PMID: 19719236
CHEMBL572565 agonist Compound 5 EC50 = 2.40 +/- 0.23 µM PMID: 19775169 PPAR_alpha
CHEMBL572566 agonist Compound 6 EC50 = 3.0 +/- 0.8 µM PMID: 19775169 PPAR_alpha
CHEMBL573015 agonist Compound 8 EC50 = 0.40 +/- 0.07 µM PMID: 19775169 PPAR_alpha
CHEMBL573018 agonist Compound 12 EC50 = 0.72 +/- 0.27 µM PMID: 19775169 PPAR_alpha
CHEMBL573252 agonist Compound 7 EC50 = 1.4 +/- 0.4 µM PMID: 19775169 PPAR_alpha
CHEMBL574606 agonist Compound 14 EC50 = 0.540 +/- 0.017 µM PMID: 19775169 PPAR_alpha
CHEMBL574607 agonist Compound 15 EC50 = 0.87 +/- 0.16 µM PMID: 19775169 PPAR_alpha
CHEMBL574813 agonist Compound D EC50 = 0.87 µM PMID: 20850970
CHEMBL574824 agonist Compound 10 EC50 = 9.4 +/- 2.3 µM PMID: 19775169 PPAR_alpha
CHEMBL578860 agonist Compound 3 EC50 = 1.21 +/- 0.04 µM PMID: 19775169 PPAR_alpha
CHEMBL583759 agonist Compound 9 EC50 = 13 +/- 3 µM PMID: 19775169 PPAR_alpha
CHEMBL590983 agonist Compound 17a IC50 = 0.036 µM EC50 = 0.003 µM PMID: 20079636
CHEMBL590984 agonist Compound 17b IC50 = 0.490 µM EC50 = 0.201 µM PMID: 20079636
CHEMBL593087 agonist Compound 17a IC50 = 1.6 µM EC50 = 0.399 µM PMID: 19783444
CHEMBL601222 agonist Compound 16a IC50 = 0.026 µM EC50 = 0.002 µM PMID: 20079636
CHEMBL601861 agonist Compound 10 IC50 = 0.574 µM EC50 = 0.338 µM PMID: 20079636
CHEMBL602262 agonist Compound 7a IC50 = 0.018 µM EC50 = 0.017 µM PMID: 20079636 PPAR_alpha
CHEMBL602468 agonist Compound 7b IC50 = 0.008 µM EC50 = 0.0008 µM PMID: 20079636
CHEMBL602469 agonist Compound 7c IC50 = 0.041 µM EC50 = 0.047 µM PMID: 20079636
CHEMBL602670 agonist Compound 7d IC50 = 0.018 µM EC50 = 0.022 µM PMID: 20079636
CHEMBL603538 agonist Compound 17c IC50 = 1.6 µM EC50 = 3.8 µM PMID: 19783444
CHEMBL604491 agonist Compound 17b IC50 = 14 µM EC50 = 1.9 µM PMID: 19783444
CHEMBL605088 agonist Compound 17d IC50 = 0.327 µM EC50 = 0.228 µM PMID: 19783444
CHEMBL606422 agonist Compound 7e IC50 = 0.012 µM EC50 = 0.001 µM PMID: 20079636
CHEMBL606425 agonist Compound 6a IC50 = 0.321 µM EC50 = 0.163 µM PMID: 20079636
CHEMBL76203 agonist Compound 23 EC50 = 0.52 µM PMID: 12824034
CHEMBL76676 agonist Compound 1l EC50 = 3 nM PMID: 11527737
PPAR_alpha
CHEMBL76786 agonist Compound 14 EC50 = 0.96 µM PMID: 12824034
CHEMBL77018 agonist Compound 19 EC50 = 0.59 µM PMID: 12824034
CHEMBL77026 agonist Compound 1 EC50 = 1.9 µM PMID: 12824034
CHEMBL77040 agonist Compound 2a EC50 = 13 nM PMID: 11527737 PPAR_alpha
CHEMBL77363 agonist Compound 18 EC50 = 1.1 µM PMID: 12824034
CHEMBL77398 agonist Compound 26 EC50 = 2.1 µM PMID: 12824034
CHEMBL78442 agonist Compound 2e EC50 = 4 nM PMID: 11527737
PPAR_alpha
CHEMBL78476 agonist Compound 1o EC50 = 230 nM PMID: 11527737 PPAR_alpha
CHEMBL78523 agonist Compound 1c EC50 = 200 nM PMID: 11527737
PPAR_alpha
CHEMBL78529 agonist Compound 12 IC50 = 290 +/- 22 nM EC50 = 285 +/- 52 nM PMID: 15115385 PPAR_alpha
CHEMBL80301 agonist Compound 1e EC50 = 50 nM PMID: 11527737
PPAR_alpha
CHEMBL80364 agonist Compound 1k EC50 = 4 nM PMID: 11527737
PPAR_alpha
CHEMBL80671 agonist Compound 1g EC50 = 20 nM PMID: 11527737
PPAR_alpha
CHEMBL80772 agonist Compound 1b EC50 = 100 nM PMID: 11527737
PPAR_alpha
CHEMBL80791 agonist Compound 2f EC50 = 6 nM PMID: 11527737
PPAR_alpha
CHEMBL80905 agonist Compound 1j EC50 = 63 nM PMID: 11527737
PPAR_alpha
CHEMBL80979 agonist Compound 2h EC50 = 4 nM PMID: 11527737 PPAR_alpha
CHEMBL81208 agonist Compound 11 IC50 = 128 +/- 4 nM EC50 = 390 +/- 35 nM PMID: 15115385 PPAR_alpha
CHEMBL81592 agonist Compound 10 IC50 = 491 +/- 32 nM EC50 = 1776 +/- 0 nM PMID: 15115385 PPAR_alpha
CHEMBL81676 agonist Compound 8e IC50 = 71 +/- 3 nM EC50 = 6 +/- 1 nM PMID: 15115385
CHEMBL82041 agonist Compound 4j Ki = 20 nM EC50 = 290 nM PMID: 22582973
CHEMBL82193 agonist Compound 13 IC50 = 2241 +/- 13 nM EC50 = 2507 +/- 50 nM PMID: 15115385 PPAR_alpha
CHEMBL83612 agonist Compound 4g Ki = 18 nM EC50 = 520 nM PMID: 22582973
CHEMBL83875 agonist Compound 4h Ki = 48 nM EC50 = 280 nM PMID: 22582973
CHEMBL84181 agonist Compound 4f Ki = 61 nM EC50 = 810 nM PMID: 22582973
CHEMBL92130 agonist Compound 22 IC50 = 0.3 µM EC50 = 0.069 µM PMID: 12873517
CHEMBL94306 agonist Compound 12 IC50 = 0.057 µM EC50 = 0.014 µM PMID: 12873517
CHEMBL94397 agonist Compound 23 IC50 = 0.03 µM EC50 = 0.023 µM PMID: 12873517
CHEMBL94496 agonist Compound 15 IC50 = 0.17 µM EC50 = 0.167 µM PMID: 12873517
CHEMBL96143 agonist Compound 26 IC50 = 0.078 µM EC50 = 0.106 µM PMID: 12873517
CHEMBL96451 agonist Compound 21 IC50 = 0.077 µM EC50 = 0.085 µM PMID: 12873517
CHEMBL96758 agonist Compound 19 IC50 = 0.226 µM EC50 = 0.353 µM PMID: 12873517
CHEMBL97529 agonist Compound 18 IC50 = 0.33 µM EC50 = 0.123 µM PMID: 12873517
CID23963137 antagonist JTP-426467 IC50 = 0.017 µM PMID: 16918585
CID44511380 antagonist 7-chloroarctinone b Kd = 2,63 µM  IC50 = 5.61 μmol/L PMID: 19684608
CID644213 antagonist GW9662 PMID: 15533890
ZINC00001758 agonist Compound 1 Kd = 110 µM PMID: 17618115
ZINC00001963 agonist pirixinic acid EC50 = 53.7 +/- 1 µM PMID: 20307981 PPAR_alpha
ZINC00003381 antagonist T0070907 Ki = 1 nM pIC50 = 1 PMID: 11877444
ZINC00057648 agonist Compound 4 Ki = 0.236 µM PMID: 20583750
ZINC00162916 agonist Compound 76 EC50 = 22.29 µM PMID: 19807106
ZINC00307531 agonist Compound 72 EC50 = 15.38 µM PMID: 19807106
ZINC00388674 agonist Compound 9 EC50 = 40.0 +/- 3.5 µM PMID: 22381047 PPAR_beta
ZINC00590168 agonist Compound (S)-10 EC50 = 0.06 µM PMID: 12904063 PPAR_alpha
ZINC00591937 agonist Compound 3a EC50 = 1.9 µM PMID: 20656494
ZINC00593304 agonist Compound 3 EC50 = 20.8 µM PMID: 21515063
PPAR_alpha
ZINC00593306 agonist Compound 7 EC50 = 25.1 µM PMID: 21515063
PPAR_alpha
ZINC00593307 agonist Compound 8 EC50 = 19.1 µM PMID: 21515063
PPAR_alpha
ZINC00593796 agonist Compound 17i IC50 = 0.005 µM EC50 = 0.015 µM PMID: 19783444
ZINC00595448 agonist Compound 14 EC50 = 3.0 µM PMID: 11738577
ZINC00602332 agonist Compound 13 pKi = 7.32 +/- 0.07 pEC50 = 7.36 +/- 0.21 PMID: 10612594
ZINC00602989 agonist Compound 5-S IC50 = 14 nM EC50 = 0.74 µM PMID: 11814790 PPAR_alpha
ZINC00603089 agonist Compound 9 EC50 = 26.4 µM PMID: 21515063
PPAR_alpha
ZINC00837921 agonist Compound 2a EC50 = 591 nM PMID: 21557540
ZINC00837926 agonist Compound 2c EC50 = 2620 nM PMID: 21557540
ZINC00968279 agonist troglitazone Ki = 6.52 +/- 0.06 pEC50 = 6.27 +/- 0.18 PMID: 11095972 PXR
ZINC00968327 agonist pioglitazone Ki = 5.91 +/- 0.02 pEC50 = 6.23 +/- 0.05 PMID: 11095972
ZINC01481822 agonist farglittazar pKi = 8.94 +/- 0.13 pEC50 = 9.47 +/- 0.44 PMID: 9836621 PPAR_alpha
ZINC01481830 agonist ragaglitazar EC50 = 0.57 +/- 0.2 µM PMID: 11831892
ZINC01482422 agonist BRL 4842 pKi = 7.57 +/- 0.03 pEC50 = 7.95 +/- 0.39 PMID: 9836620
ZINC01485982 agonist Compound (R)-2Ba IC50 = 2.68 µM EC50 = 0.787 µM PMID: 19349176 PPAR_alpha
ZINC01485983 agonist aleglitazar IC50 = 0.019 µM EC50 = 0.021 µM PMID: 19349176 PPAR_alpha
ZINC01491415 agonist Compound 9a Ki = 0.9 µM EC50 = 0.7 µM PMID: 12443777 PPAR_alpha
ZINC01494687 agonist Compound 6 IC50 = 3017 +/- 117 nM EC50 = 2059 +/- 243 nM PMID: 11405642 PPAR_alpha
ZINC01530886 agonist Compound 1 IC50 = 12.2 µM EC50 = 2.02 µM PMID: 20079636
ZINC01549535 agonist Compound 20 EC50 = 2.9 µM PMID: 12482434
PPAR_alpha
ZINC01550501 agonist LY-465608 IC50 = 0.55 µM EC50 = 0.88 µM PMID: 15293980 PPAR_alpha
ZINC01550769 agonist tesaglitazar EC50 = 0.704 µM PMID: 11587644  PPAR_alpha
ZINC01551626 agonist Compound 1 IC50 = 1 nM EC50 = 2 nM PMID: 19507861
ZINC01553275 agonist Compound 34 IC50 = 1.4 µM EC50 = 0.4 µM PMID: 15950464 PPAR_alpha
ZINC01553970 agonist Compound 19 EC50 = 0.3 µM PMID: 12482434
PPAR_alpha
ZINC01553971 agonist Compound 18 EC50 = 0.9 µM PMID: 12482434 PPAR_beta
ZINC01554177 agonist Compound 5d Ki = 1.6 µM EC50 = 0.6 µM PMID: 12443777 PPAR_alpha
ZINC01554219 agonist Compound 9 Ki = 3.1 nM EC50 = 6 nM PMID: 12617924
PPAR_alpha
ZINC01554220 agonist Compound 6 Ki = 30 nM EC50 = 60 nM PMID: 12617924
PPAR_alpha
ZINC01554391 agonist Compound 7 IC50 = 94 nM EC50 = 9 PMID: 12657263
PPAR_alpha
ZINC01725417 agonist Compound 1a IC50 = 1326 +/- 373 nM Transactiv. = 33.4 +/- 7.8 % PMID: 18809325
ZINC01727800 agonist Compound 93 EC50 = 15.3 nM PMID: 21482446
ZINC01846640 agonist drosophilin A PMID: 18667308
ZINC01882025 agonist Compound 1f IC50 = 1439 +/- 183 nM Transactiv. = 60.9 +/- 9.3 % PMID: 18809325
ZINC01884638 agonist Compound 1j IC50 = 2098 +/- 611 nM Transactiv. = 13.8 +/- 1.5 % PMID: 18809325
ZINC01902774 agonist Compound 3b Ki = 52 nM EC50 = 240 nM PMID: 11720854 PPAR_alpha
ZINC01910340 agonist YPA EC50 = 0.17 +/- 0.08 µM PMID: 11831892 PPAR_alpha
ZINC01910883 agonist Compound 46 IC50 = 0.25 µM EC50 = 0.08 µM PMID: 15163205 PPAR_alpha
ZINC01910889 agonist Compound 49 IC50 = 4.4 µM EC50 = 5.0 µM PMID: 15163205
ZINC02023761 agonist Compound 1m IC50 = 13521 +/- 901 nM Transactiv. = 19.7 +/- 3.6 % PMID: 18809325
ZINC02027112 agonist Compound 1g IC50 = 1294 +/- 484 nM Transactiv. = 22.7 +/- 6.4 % PMID: 18809325
ZINC02027132 agonist Compound 1i IC50 = 747 +/- 32 nM Transactiv. = 19.1 +/- 4.3 % PMID: 18809325
ZINC02541693 agonist L-165,041 EC50 = 1824 nM PMID: 16797985
PPAR_alpha
ZINC03122867 agonist Compound 1h IC50 = 703 +/- 130 nM Transactiv. = 16.0 +/- 9.5 % PMID: 18809325
ZINC03122869 agonist Compound 1l IC50 = 382 +/- 122 nM Transactiv. = 41.6 +/- 9.5 % PMID: 18809325
ZINC03806787 agonist AD-7057 pKi = 8.37 +/- 0.04 pEC50 = 8.50 +/- 0.58 PMID: 9836620
ZINC03817160 agonist TZD18 Ki = 0.06 µM EC50 = 0.01 µM PMID: 15293980 PPAR_alpha
ZINC03819472 agonist NNC 61-3058 EC50 = 2.0 µM PMID: 17379517
PPAR_alpha
ZINC03819473 agonist Compound 6 EC50 = 1.13 +/- 0.33 µM PMID: 14584939
PPAR_alpha
ZINC03832270 agonist Compound 14 pKi = 9.07 +/- 0.02 pEC50 = 9.61 +/- 0.17 PMID: 9836621
ZINC03832271 agonist Compound 17 pKi = 9.06 +/- 0.05 pEC50 = 8.68 +/- 0.07 PMID: 9836621
ZINC03832272 agonist Compound 15 pKi = 9.05 +/- 0.07 pEC50 = 8.82 +/- 0.33 PMID: 9836621
ZINC03832275 agonist Compound 4 pKi = 8.96 +/- 0.11 pEC50 = 10.0 +/- 0.5 PMID: 9836621
ZINC03832276 agonist Compound 57 pKi = 6.72 +/- 0.21 pEC50 = 7.82 +/- 0.24 PMID: 9836622 PPAR_alpha
ZINC03832277 agonist Compound 9 pKi = 8.9 +/- 0.05 pEC50 = 8.43 +/- 0.16 PMID: 9836621
ZINC03832278 agonist Compound 18 pKi = 8.85 +/- 0.02 pEC50 = 8.04 +/- 0.33 PMID: 9836620
ZINC03832279 agonist Compound 16 pKi = 8.85 +/- 0.14 pEC50 = 8.74 +/- 0.23 PMID: 9836621
ZINC03832280 agonist Compound 19 pKi = 8.83 +/- 0.5 pEC50 = 8.58 +/- 0.39 PMID: 9836620
ZINC03832281 agonist Compound 11 pKi = 8.80 +/- 0.06 pEC50 = 9.90 +/- 0.47 PMID: 9836621
ZINC03832282 agonist Compound 8 pKi = 8.75 +/- 0.24 pEC50 = 8.97 +/- 0.42 PMID: 9836621
ZINC03832283 agonist Compound 59 pKi = 8.74 +/- 0.02 pEC50 = 9.04 +/- 0.17 PMID: 9836622
ZINC03832284 agonist Compound 13 pKi = 8.72 +/- 0.05 pEC50 = 8.98 +/- 0.15 PMID: 9836621
ZINC03832292 agonist Compound 28 pKi = 8.43 +/- 0.02 pEC50 = 6.97 +/- 0.43 PMID: 9836620
ZINC03832293 agonist Compound 63 pKi = 8.43 +/- 0.02 pEC50 = 9.15 +/- 0.3 PMID: 9836622
ZINC03832295 agonist Compound 10 pKi = 8.32 +/- 0.02 pEC50 = 7.91 +/- 0.22 PMID: 9836621
ZINC03832296 agonist Compound 25 pKi = 8.29 +/- 0.06 pEC50 = 8.30 +/- 0.27 PMID: 9836620
ZINC03832298 agonist Compound 16 pKi = 8.19 +/- 0.032 pEC50 = 7.30 +/- 0.17 PMID: 9836620
ZINC03832300 agonist Compound 61 pKi = 7.81 +/- 0.12 pEC50 = 7.49 +/- 0.43 PMID: 9836622
ZINC03832301 agonist Compound 18 pKi = 7.56 +/- 0.12 pEC50 = 5.91 +/- 0.2 PMID: 9836621
ZINC03832304 agonist Compound 70 pKi = 7.71 +/- 0.08 PMID: 9836621
ZINC03832305 agonist Compound 24 pKi = 7.07 +/- 0.73 pEC50 = 6.31 +/- 0.19 PMID: 9836620
ZINC03832306 agonist Compound 72 pKi = 7.03 +/- 0.02 PMID: 9836621
ZINC03832308 agonist Compound 50 pKi = 6.93 PMID: 9836621
ZINC03832309 agonist Compound 27 pKi = 6.91 +/- 0.05 pEC50 = 5.74 +/- 0.46 PMID: 9836620
ZINC03834054 agonist Compound 5 IC50 = 140 nM EC50 = 23 nM PMID: 12657263
LXR_alpha
ZINC03834057 agonist Compound 21 pKi = 7.55 +/- 0.08 pEC50 = 6.78 +/- 0.77 PMID: 9836620
ZINC03834058 agonist Compound 23 pKi = 7.49 +/- 0.01 pEC50 = 6.03 +/- 0.38 PMID: 9836620
ZINC03834059 agonist Compound 22 pKi = 7.48 +/- 0.01 pEC50 = 5.86 +/- 0.42 PMID: 9836620
ZINC03870645 agonist 15d-PGJ2 PMID: 18809325 
ZINC03928667 agonist Compound (R)-12 EC50 = 100 nM PMID: 14695833
ZINC03929313 agonist Krp-297 Ki = 0.33 µM EC50 = 0.80 µM PMID: 15293980 PPAR_alpha
ZINC03935839 agonist Compound 1 IC50 = 0.19 µM EC50 = 0.04 µM PMID: 18511276 PPAR_alpha
ZINC03940632 agonist Compound 4e Ki = 6.9 nM EC50 = 4.7 nM PMID: 11720854
PPAR_alpha
ZINC03942600 agonist Compound 12b IC50 = 11 nM EC50 = 4 nM PMID: 19530681
ZINC03942601 agonist Compound 4 IC50 = 2 nM EC50 = 3 nM PMID: 19507861
ZINC03942731 agonist Compound 24 IC50 = 25 nM EC50 = 0.01 µM PMID: 16737814 PPAR_alpha
ZINC03942732 agonist Compound 13 IC50 = 251 nM EC50 = 0.76 µM PMID: 16737814 PPAR_alpha
ZINC03942733 agonist Compound 14 IC50 = 742 nM EC50 = 1.1 µM PMID: 16737814 PPAR_alpha
ZINC03942734 agonist Compound 18 IC50 = 321 nM EC50 = 0.47 µM PMID: 16737814 PPAR_alpha
ZINC03942736 agonist Compound 25 IC50 = 135 nM EC50 = 0.14 µM PMID: 16737814 PPAR_alpha
ZINC03950327 agonist Compound 1b IC50 = 34 +/- 3 nM EC50 = 361 +/- 35 nM PMID: 15582409 PPAR_alpha
ZINC03964260 agonist Compound 4 IC50 = 1.58 µM max at 3µM = 25 % PMID: 15801817 PPAR_alpha
ZINC03976748 agonist Compound 10 EC50 = 10.0 µM PMID: 17243659 PPAR_beta
ZINC03989107 agonist Compound 31 IC50 = 2.9 µM EC50 = 1.2 µM PMID: 15950464 PPAR_alpha
ZINC03989108 agonist Compound 29 IC50 = 2.6 µM EC50 = 0.5 µM PMID: 15950464 PPAR_alpha
ZINC03989109 agonist Compound 50 IC50 = 3.8 µM EC50 = 0.7 µM PMID: 15950464 PPAR_alpha
ZINC03990563 agonist Compound 14e EC50 = 0.16 µM PMID: 22197396 PPAR_alpha
ZINC03991715 agonist Compound 2 IC50 = 10 +/- 1 nM EC50 = 4 +/- 1 nM PMID: 15115385 PPAR_alpha
ZINC03992538 agonist Compound 47 IC50 = 1.4 µM EC50 = 7.6 µM PMID: 15163205
ZINC03992541 agonist Compound 48 IC50 = 0.26 µM EC50 = 0.17 µM PMID: 15163205 PPAR_alpha
ZINC03995991 agonist GW7647 EC50 = 1.1 µM PMID: 11354382 PPAR_alpha
ZINC04137602 agonist Compound 66 pKi = 9.01 pEC50 = 9.24 +/- 0.42 PMID: 9836622
ZINC04137603 agonist Compound 12 pKi = 8.96 +/- 0.05 pEC50 = 9.22 +/- 0.27 PMID: 9836621
ZINC04137607 agonist Compound 65 pKi = 8.62 +/- 0.03 pEC50 = 9.52 +/- 0.41 PMID: 9836622
ZINC04137611 agonist Compound 64 pKi = 8.52 +/- 0.03 pEC50 = 9.04 +/- 0.66 PMID: 9836622
ZINC04137612 agonist Compound 26 pKi = 8.48 +/- 0.1 pEC50 = 7.54 +/- 0.36 PMID: 9836620
ZINC04137617 agonist Compound 19 pKi = 7.91 +/- 0.06 pEC50 = 5.52 +/- 0.24 PMID: 9836621
ZINC04137623 agonist Compound 69 pKi = 7.04 +/- 0.27 PMID: 9836621
ZINC04215181 agonist carbacyclin EC50 = 13 µM PMID: 11831892 PPAR_alpha
ZINC04474696 agonist Compound 2 Ki = 1500 nM EC50 = 30000 nM PMID: 22582973 PPAR_alpha
ZINC04661798 agonist Compound 1b IC50 = 1088 +/- 208 µM  = 25.8 +/- 1.8 % PMID: 18809325
ZINC04662097 agonist Compound 1e IC50 = 302 +/- 54 nM Transactiv. = 24.5 +/- 4.1 % PMID: 18809325
ZINC04744962 agonist Compound 1d IC50 = 1187 +/- 149 nM Transactiv. = 33.2 +/- 11.4 % PMID: 18809325
ZINC04744966 agonist Compound 1k IC50 = 10712 +/- 1223 nM Transactiv. = 8.4 +/- 2.6 % PMID: 18809325
ZINC04745003 agonist Compound 1c IC50 = 407 +/- 10 nM Transactiv. = 31.3 +/- 4.0 % PMID: 18809325
ZINC04777896 agonist Compound 3 EC50 = 58.6 +/- 7.5 µM PMID: 22381047 PPAR_beta
ZINC05158604 agonist APH1 IC50 = 0.85 µM EC50 = 5 µM PMID: 22579420
ZINC05948807 antagonist G3335 IC50 = 8,67 µM PMID: 18329752
ZINC06001877 agonist Compound 6 EC50 = 18.9 +/- 1.7 µM PMID: 22381047 PPAR_beta
ZINC08022594 agonist GW-0742 EC50 = 2.0 +/- 1.3 µM PMID: 12699745 PPAR_beta
ZINC08035065 agonist Compound 1 PMID: 20036122
ZINC08455242 agonist MDG559 EC50 = 0.682 +/- 0.357 µM PMID: 22582973 PPAR_beta
ZINC08536382 agonist Compound 57 pKi = 6.72 +/- 0.21 pEC50 = 7.82 +/- 0.24 PMID: 9836622
ZINC08730640 agonist Compound S-5 EC50 = 7.2 +/- 1.5 µM PMID: 16107150 PPAR_alpha
ZINC08730641 agonist Compound R-5 EC50 = 12.5 +/- 2.49 µM PMID: 16107150 PPAR_alpha
ZINC09933927 agonist Compound 9 IC50 = 13 µM PMID: 18821746
ZINC11687575 agonist Compound 2d EC50 = 1320 nM PMID: 21557540
ZINC12358060 agonist Compound 17 pKi = 8.28 +/- 0.03 PEC50 = 8.04 +/- 0.11 PMID: 9836620
ZINC12358061 agonist Compound 1 pKi = 8.83 +/- 0.14 pEC50 = 8.58 +/- 0.39 PMID: 9836622
ZINC12358072 agonist Compound 2 pKi = 7.93 +/- 0.01 pEC50 = 6.64 +/- 0.2 PMID: 9836620
ZINC12358074 agonist Compound 6 pKi = 8.70 +/- 0.01 pEC50 = 7.09 +/- 0.39 PMID: 9836621
ZINC12358076 agonist Compound 7 pKi = 9.16 +/- 0.04 pEC50 = 8.03 +/- 0.55 PMID: 9836621
ZINC12358087 agonist Compound 20 pKi = 8.59 +/- 0.1 pEC50 = 7.51 +/- 0.33 PMID: 9836621
ZINC12358105 agonist Compound 36 pKi = 8.39 +/- 0.11 pEC50 = 8.54 +/- 1.21 PMID: 9836622
ZINC12358130 agonist Compound 56 pKi = 8.79 +/- 0.04 pEC50 = 9.55 +/- 0.06 PMID: 9836622
ZINC12358131 agonist Compound 58 pKi = 9.03 +/- 0.03 pEC50 = 8.83 +/- 0.38 PMID: 9836622
ZINC12358132 agonist Compound 59 pKi = 8.74 +/- 0.02 pEC50 = 9.04 +/- 0.17 PMID: 9836622
ZINC12358138 agonist Compound 64 pKi = 8.52 +/- 0.03 pEC50 = 9.04 +/- 0.66 PMID: 9836622
ZINC12358139 agonist Compound 65 pKi = 8.62 +/- 0.03 pEC50 = 9.52 +/- 0.41 PMID: 9836622
ZINC12358140 agonist Compound 66 pKi = 9.01 +/- 0.00 pEC50 = 9.24 +/- 0.42 PMID: 9836622
ZINC12358141 agonist Compound 4 EC50 = 0.006 µM PMID: 10508427
PPAR_alpha
ZINC12358142 agonist Compound 6 EC50 = 1.6 µM PMID: 10508427 PPAR_alpha
ZINC12358143 agonist Compound 5a Ki = 0.4 µM EC50 = 0.3 µM PMID: 12443777 PPAR_alpha
ZINC12358144 agonist Compound 5b Ki = 0.6 nM EC50 = 0.8 µM PMID: 12443777 PPAR_alpha
ZINC12358145 agonist Compound 5c Ki = 1 µM EC50 = 0.7 µM PMID: 12443777
ZINC12358146 agonist Compound 5e Ki = 3.6 µM EC50 = 0.7 µM PMID: 12443777
ZINC12358147 agonist Compound 5f Ki = 1.5 µM EC50 = 3.2 µM PMID: 12443777
ZINC12358148 agonist Compound 9b Ki = 0.5 µM EC50 = 1 µM PMID: 12443777 PPAR_alpha
ZINC12358149 agonist Compound 9c Ki = 1.2 µM EC50 = 0.3 µM PMID: 12443777
ZINC12358150 agonist Compound 9d Ki = 0.7 µM EC50 = 0.3 µM PMID: 12443777
ZINC12358151 agonist Compound 10a Ki = 0.18 µM EC50 = 0.4 µM PMID: 12443777
ZINC12358152 agonist Compound 10b Ki = 0.17 µM EC50 = 04 µM PMID: 12443777
ZINC12358153 agonist Compound 10c Ki = 0.1 µM EC50 = 1.3 µM PMID: 12443777
ZINC12358154 agonist Compound 10d Ki = 0.16 µM EC50 = 0.45 µM PMID: 12443777
ZINC12358170 agonist Compound 5 IC50 = 3120 +/- 247 nM EC50 = 2751 +/- 91 nM PMID: 11405642 PPAR_alpha
ZINC12358171 agonist Compound 7 IC50 = 4556 +/- 308 nM EC50 = 1716 +/- 398 nM PMID: 11405642 PPAR_alpha
ZINC12358193 agonist Compound 3p EC50 = 0.011 +/- 0.0029 µM PMID: 11831892 PPAR_alpha
ZINC12358195 agonist Compound 3r EC50 = 0.33 +/- 0.29 µM PMID: 11831892 PPAR_alpha
ZINC12358196 agonist Compound 3s EC50 = 0.044 +/- 0.029 µM PMID: 11831892 PPAR_alpha
ZINC12358209 agonist Compound 7 EC50 = 2.7 µM PMID: 12482434
PPAR_alpha
ZINC12358210 agonist Compound 8 EC50 = 8.5 µM PMID: 12482434
PPAR_alpha
ZINC12358211 agonist Compound 9 EC50 = 4.0 µM PMID: 12482434
PPAR_alpha
ZINC12358212 agonist Compound 10 EC50 = 0.6 µM PMID: 12482434
PPAR_alpha
ZINC12358213 agonist Compound 11 EC50 = 1.7 µM PMID: 12482434
PPAR_alpha
ZINC12358214 agonist Compound 12 EC50 = 1.5 µM PMID: 12482434
PPAR_alpha
ZINC12358215 agonist Compound 13 EC50 = 4.3 µM PMID: 12482434
PPAR_alpha
ZINC12358216 agonist Compound 14 EC50 = 0.8 µM PMID: 12482434
PPAR_alpha
ZINC12358217 agonist Compound 15 EC50 = 2.0 µM PMID: 12482434
PPAR_alpha
ZINC12358218 agonist Compound 16 EC50 = 3.1 µM PMID: 12482434
PPAR_alpha
ZINC12358219 agonist Compound 17 EC50 = 2.2 µM PMID: 12482434
PPAR_alpha
ZINC12358236 agonist Compound 2 Ki = 11 nM EC50 = 4 nM PMID: 12617924
PPAR_alpha
ZINC12358237 agonist Compound 4 Ki = 100.0 nM EC50 = 193 nM PMID: 12617924
PPAR_alpha
ZINC12358238 agonist Compound 5 Ki = 32 nM EC50 = 194 nM PMID: 12617924
PPAR_alpha
ZINC12358239 agonist Compound 7 Ki = 17 nM EC50 = 10 nM PMID: 12617924
PPAR_alpha
ZINC12358240 agonist Compound 10 Ki = 26 nM EC50 = 52 nM PMID: 12617924
PPAR_alpha
ZINC12358241 agonist Compound 14 Ki = 32 nM Max % at 3µM = 99 % PMID: 12617924
PPAR_alpha
ZINC12358242 agonist Compound 15 Ki = 8.9 nM EC50 = 485 nM PMID: 12617924
PPAR_alpha
ZINC12358243 agonist Compound 16 Ki = 52 nM EC50 = 37 nM PMID: 12617924
PPAR_alpha
ZINC12358244 agonist Compound 17 Ki = 20 nM EC50 = 20 nM PMID: 12617924
PPAR_alpha
ZINC12358245 agonist Compound 27 Ki = 152 nM EC50 = 254 nM PMID: 12617924
PPAR_alpha
ZINC12358246 agonist Compound 28 Ki = 13 nM EC50 = 29 nM PMID: 12617924
PPAR_alpha
ZINC12358247 agonist Compound 18 Ki = 34 nM EC50 = 75 nM PMID: 12617924
PPAR_alpha
ZINC12358248 agonist Compound 19 Ki = 22 nM EC50 = 27 nM PMID: 12617924
PPAR_alpha
ZINC12358250 agonist Compound 20 Ki = 20 nM EC50 = 16 nM PMID: 12617924
PPAR_alpha
ZINC12358252 agonist Compound 21 Ki = 2.4 nM EC50 = 2 nM PMID: 12617924
PPAR_alpha
ZINC12358253 agonist Compound 24 Ki = 52 nM EC50 = 87 nM PMID: 12617924
PPAR_alpha
ZINC12358254 agonist Compound 25 Ki = 41 nM EC50 = 100 nM PMID: 12617924
PPAR_alpha
ZINC12358255 agonist Compound 29 Ki = 616 nM Max % at 3µM = 72% PMID: 12617924
PPAR_alpha
ZINC12358256 agonist Compound 30 Ki = 145 nM EC50 = 156 nM PMID: 12617924
PPAR_alpha
ZINC12358257 agonist Compound 1 IC50 = 580 nM EC50 = 230 nM PMID: 12657263
PPAR_alpha
ZINC12358258 agonist Compound 2 IC50 = 300 nM EC50 = 70 nM PMID: 12657263
PPAR_alpha
ZINC12358259 agonist Compound 3 IC50 = 48 nM EC50 = 15 nM PMID: 12657263
PPAR_alpha
ZINC12358260 agonist Compound 4 IC50 = 110 nM EC50 = 19 nM PMID: 12657263
PPAR_alpha
ZINC12358261 agonist Compound 6 IC50 = 560 nM EC50 = 102 nM PMID: 12657263
PPAR_alpha
ZINC12358348 agonist Compound 15 IC50 = 4900 +/- 1000 nM EC50 = 2700 +/- 63 nM PMID: 14613314
PPAR_alpha
ZINC12358350 agonist Compound 17 IC50 = 1700 +/- 120 nM EC50 = 2600 +/- 47 nM PMID: 14613314
PPAR_alpha
ZINC12358351 agonist Compound 18 IC50 = 520 +/- 27 nM EC50 = 1500 +/- 130 nM PMID: 14613314
PPAR_alpha
ZINC12358352 agonist Compound 19 IC50 = 1700 +/- 190 nM EC50 = 2300 +/- 80 nM PMID: 14613314 PPAR_beta
ZINC12358365 agonist Compound (R)-56 EC50 = 274 nM PMID: 14695833
ZINC12358369 agonist Compound (S)-12 EC50 = 1200 PMID: 14695833
ZINC12358426 agonist Compound (R)-46 EC50 = 295 nM PMID: 14695833
ZINC12358427 agonist Compound (S)-46 EC50 = 1000 nM PMID: 14695833
ZINC12358430 agonist Compound (S)-50 EC50 = 570 nM PMID: 14695833
ZINC12358431 agonist Compound (R)-50 EC50 = 152 nM PMID: 14695833
ZINC12358524 agonist Compound 14 IC50 = 388 +/- 174 nM EC50 = 382 +/- 52 nM PMID: 15115385 PPAR_alpha
ZINC12358525 agonist Compound 15 IC50 = 14 +/- 2 nM EC50 = 3 +/- 0 nM PMID: 15115385 PPAR_alpha
ZINC12358526 agonist ly-510929 ED50 = 0.003 mg/kg EC50 = 0.004 µM PMID: 15293980 PPAR_alpha
ZINC12358528 agonist Compound 17 IC50 = 15 +/- 2 nM EC50 = 1 +/- 0 nM PMID: 15115385
ZINC12358565 agonist Compound 2a IC50 = 1.77 µM EC50 = 3.6 µM PMID: 17292606 PPAR_alpha
ZINC12358567 agonist Compound 6 IC50 = 1.62 µM EC50 = 1.10 µM PMID: 15801817 PPAR_alpha
ZINC12358572 agonist Compound 9 IC50 = 1.22 µM EC50 = 1.3 µM PMID: 15801817 PPAR_alpha
ZINC12358582 agonist Compound 37 IC50 = 0.22 µM EC50 = 0.36 µM PMID: 15974597 PPAR_alpha
ZINC12358583 agonist Compound 38 IC50 = 0.21 µM EC50 = 0.48 µM PMID: 15974597 PPAR_alpha
ZINC12358584 agonist Compound 39 IC50 = 0.22 µM EC50 = 0.18 µM PMID: 15974597 PPAR_alpha
ZINC12358585 agonist Compound 40 IC50 = 0.075 µM EC50 = 0.15 µM PMID: 15974597 PPAR_alpha
ZINC12358586 agonist Compound 42 IC50 = 0.20 µM Max = 59 % PMID: 15974597 PPAR_alpha
ZINC12358587 agonist Compound 43 IC50 = 0.21 µM Max = 56 % PMID: 15974597 PPAR_alpha
ZINC12358589 agonist c01 EC50 = 0.64 µM PMID: 15974597
ZINC12358651 agonist 9 cis-retinoic acid PMID: 15537571
RAR_alpha
ZINC12504466 agonist EHA IC50 = 2.024 EC50 = 3.87 µM PMID: 16451087 
PPAR_alpha
ZINC13207359 agonist Compound 96 EC50 = 224 nM PMID: 21482446
ZINC13489471 agonist Compound 7a EC50 = 7.9 +/- 1.3 µM PMID: 12699745 PPAR_beta
ZINC13489472 agonist Compound 7b EC50 = 7.04 +/- 3.6 µM PMID: 12699745 PPAR_beta
ZINC13489473 agonist Compound 7c EC50 = 2.7 +/- 3.3 µM PMID: 12699745 PPAR_beta
ZINC13489474 agonist Compound 7d EC50 = 4.2 +/- 2.2 µM PMID: 12699745 PPAR_beta
ZINC13489475 agonist Compound 7e EC50 = 3.3 +/- 1.9 µM PMID: 12699745 PPAR_beta
ZINC13489477 agonist Compound 7g EC50 = 9.8 +/- 8.0 µM PMID: 12699745 PPAR_beta
ZINC13489479 agonist Compound 7i EC50 = 6.4 +/- 3.9 µM PMID: 12699745 PPAR_beta
ZINC13489480 agonist Compound 7j EC50 = 1.61 +/- 2.6 µM PMID: 12699745 PPAR_beta
ZINC13539257 agonist Compound 1 Ki = 1100 nM PMID: 12951090 PPAR_alpha
ZINC13539263 agonist Compound 2 Ki = 5940 nM PMID: 12951090 PPAR_alpha
ZINC13539269 agonist Compound 3 Ki = 8530 nM PMID: 12951090 PPAR_alpha
ZINC13539289 agonist Compound 7 Ki = 985 nM PMID: 12951090 PPAR_alpha
ZINC13539294 agonist Compound 8 Ki = 2680 nM PMID: 12951090 PPAR_alpha
ZINC13539307 agonist Compound 10 (S) Ki = 618 nM PMID: 12951090 PPAR_alpha
ZINC13539316 agonist Compound 14 Ki = 175 nM PMID: 12951090 PPAR_alpha
ZINC13539321 agonist Compound 15 Ki = 87 nM PMID: 12951090 PPAR_alpha
ZINC13539327 agonist Compound 16 Ki = 104 nM PMID: 12951090 PPAR_alpha
ZINC13539332 agonist Compound 18 Ki = 197 nM PMID: 12951090 PPAR_alpha
ZINC13671681 agonist Compound R-6 EC50 = 5.4 +/- 1.04 µM PMID: 16107150 PPAR_alpha
ZINC13671683 agonist Compound S-6 EC50 = 8.9 +/- 1.85 µM PMID: 16107150 PPAR_alpha
ZINC13671685 agonist Compound R-7 EC50 = 10.5 +/- 2.43 µM PMID: 16107150 PPAR_alpha
ZINC13671689 agonist Compound 8 EC50 = 0.9 +/- 0.16 µM PMID: 16107150 PPAR_alpha
ZINC13671691 agonist Compound 9 EC50 = 20.1 +/- 1.76 µM PMID: 16107150 PPAR_alpha
ZINC13671693 agonist Compound 10 EC50 = 12.4 +/- 0.54 µM PMID: 16107150 PPAR_alpha
ZINC13671695 agonist Compound (S)-1 EC50 = 0.48 +/- 0.08 µM PMID: 19053776 PPAR_alpha
ZINC13671697 agonist LT248 EC50 = 3.6 +/- 0.52 µM PMID: 16107150 PPAR_alpha
ZINC13671698 agonist Compound 13 EC50 = 25.7 +/- 3.64 µM PMID: 16107150 PPAR_alpha
ZINC13671700 agonist Compound 14 EC50 = 1.6 +/- 0.29 µM PMID: 16107150 PPAR_alpha
ZINC13671702 agonist Compound 15 EC50 = 1.5 +/- 0.09 µM PMID: 16107150 PPAR_alpha
ZINC13677956 agonist Compound 12 IC50 = 0.422 µM EC50 = 0.690 µM PMID: 16366601
ZINC13677958 agonist Compound 13 IC50 = 1.986 µM EC50 = 2.393 µM PMID: 16366601
ZINC13677960 agonist Compound 14 IC50 = 0.152 µM EC50 = 0.230 µM PMID: 16366601
ZINC13677962 agonist Compound 15 IC50 = 1.047 µM EC50 = 1.350 µM PMID: 16366601
ZINC13677964 agonist Compound 16 IC50 = 0.774 µM EC50 = 1.981 µM PMID: 16366601
ZINC13677966 agonist Compound 17 IC50 = 0.105 µM EC50 = 0.280 µM PMID: 16366601
ZINC13677970 agonist Compound 19 IC50 = 1.050 µM EC50 = 1.490 µM PMID: 16366601
ZINC13677984 agonist Compound 23 IC50 = 1.098 µM EC50 = 2.190 µM PMID: 16366601
ZINC13677986 agonist Compound 24 IC50 = 0.584 µM EC50 = 1.200 µM PMID: 16366601
ZINC13677996 agonist Compound 27 IC50 = 1.123 µM EC50 = 1.490 µM PMID: 16366601
ZINC13677998 agonist Compound 28 IC50 = 0.127 µM EC50 = 0.430 µM PMID: 16366601
ZINC13678000 agonist Compound 29 IC50 = 0.120 µM EC50 = 0.290 µM PMID: 16366601
ZINC13678004 agonist Compound 31 IC50 = 0.759 µM EC50 = 9.170 µM PMID: 16366601
ZINC13678008 agonist Compound 33 IC50 = 1.679 µM EC50 = 2.820 µM PMID: 16366601
ZINC13678010 agonist Compound 34 IC50 = 3.968 µM EC50 = 4.150 µM PMID: 16366601
ZINC13782252 agonist Compound 53 pKi = 6.95 +/- 0.02 PMID: 9836621
ZINC13782253 agonist Compound 37 pKi = 6.43 +/- 0.02 PMID: 9836621
ZINC13782271 agonist Compound 77 pKi = 6.97 +/- 0.02 PMID: 9836621
ZINC13905502 agonist Compound 2g EC50 = 762 nM PMID: 21557540
ZINC13973809 agonist Compound (S)-2Ba IC50 = 0.021 µM EC50 = 0.021 µM PMID: 19349176 PPAR_alpha
ZINC13973811 agonist Compound (R)-2Aa IC50 = 1.44 µM EC50 = 1.21 µM PMID: 19349176 PPAR_alpha
ZINC13973813 agonist Compound (R)-3Aa IC50 = 1.57 µM EC50 = 0.122 µM PMID: 19349176 PPAR_alpha
ZINC13974182 agonist Compound 17j IC50 = 0.003 µM EC50 = 0.013 µM PMID: 19783444 PPAR_alpha
ZINC13976592 agonist Compound 10 IC50 = 274 nM EC50 = 0.09 µM PMID: 16737814 PPAR_alpha
ZINC13980247 agonist Compound 10 (S) IC50 = 1130 +/- 0 EC50 = 674 +/- 0 nM PMID: 16970391 PPAR_beta
ZINC13981013 agonist Compound 43 IC50 = 6.0 µM EC50 = 3 µM PMID: 15950464 PPAR_alpha
ZINC13982030 agonist Compound 13 EC50 = 43.5 PMID: 18083521
PPAR_alpha
ZINC13983069 agonist Compound 7 EC50 = 0.006 µM PMID: 18947994 PPAR_alpha
ZINC13983071 agonist Compound 11 EC50 = 0.008 µM PMID: 18947994
PPAR_alpha
ZINC13983073 agonist Compound 13 EC50 = 0.015 µM PMID: 18947994 PPAR_alpha
ZINC13983075 agonist Compound 9 EC50 = 0.008 µM PMID: 18947994
PPAR_alpha
ZINC13983079 agonist Compound 27 EC50 = 0.030 µM PMID: 18947994
PPAR_alpha
ZINC13983521 agonist Compound 13a Transactiv. = 1.0 PMID: 18805005 PPAR_beta
ZINC13983527 agonist Compound 9 Transactiv. = 1.0 PMID: 18805005 PPAR_beta
ZINC13983851 agonist Compound 3d SS EC50 = 6 nM PMID: 16275080 PPAR_alpha
ZINC14096589 agonist Compound 5 EC50 = 0.28 µM PMID: 10508427
PPAR_alpha
ZINC14115100 agonist Compound 8 EC50 = 1.0 µM PMID: 10508427
PPAR_alpha
ZINC14209392 agonist Compound 9 (R) IC50 = 5 +/- 1 nM EC50 = 4 +/- 0 nM PMID: 16970391
PPAR_alpha
ZINC14209394 agonist Compound 14 IC50 = 6 +/- 0 nM EC50 = 8 +/- 0 nM PMID: 16970391
PPAR_alpha
ZINC14262259 agonist Compound 7 EC50 = 0.20 µM PMID: 10508427 PPAR_alpha
ZINC14588894 agonist Compound 7 EC50 = 21.7 +/- 1.1 µM PMID: 22381047 PPAR_beta
ZINC14811756 agonist Compound 68 EC50 = 18.86 µM PMID: 19807106
ZINC14972488 agonist Compound 4 EC50 = 680 nM PMID: 18023179
LXR_alpha
ZINC15112963 agonist Compound 10 EC50 = 19.3 +/- 1.8 µM PMID: 22381047 PPAR_beta
ZINC15194346 agonist Compound 1 EC50 = 16.7 µM PMID: 11975517
ZINC16052147 agonist dry EC50 = 2.21 µM PMID: 17034149 PPAR_alpha
ZINC16052148 agonist drd EC50 = 0.21 µM PMID: 17034149
PPAR_alpha
ZINC16052165 agonist LT160 Kd = 684.8 +/- 106.8 nM EC50 = 73.3 +/- 49.9 nM PMID: 17403688
ZINC1842811 antagonist SR-202 IC50 = 140 µM PMID: 12403851
ZINC18847051 agonist Compound 70 EC50 = 26.94 µM PMID: 19807106
ZINC2012859 antagonist halofenate IC50 = 40 µM PMID: 18329752
ZINC26500814 agonist Compound 1 EC50 = 5.7 µM PMID: 16643023
ZINC26743888 agonist Compound 19 EC50 = 30 nM PMID: 11677135
PPAR_alpha
ZINC26744992 agonist Compound 20 EC50 = 81 nM PMID: 11677135
PPAR_alpha
ZINC26747370 agonist Compound 21 EC50 = 170 nM PMID: 11677135
PPAR_alpha
ZINC26747391 agonist Compound 18 EC50 = 0.5 nM PMID: 11677135
PPAR_alpha
ZINC26749852 agonist Compound 22 EC50 = 320 nM PMID: 11677135
PPAR_alpha
ZINC26833155 agonist Compound 3d Ki = 620 nM EC50 = 2600 nM PMID: 11720854
ZINC26833878 agonist Compound 3e Ki = 280 nM EC50 = 590 nM PMID: 11720854
ZINC26834647 agonist Compound 4a Ki = 850 nM EC50 = 410 nM PMID: 11720854
ZINC26836181 agonist Compound 3a Ki = 2100 nM EC50 = 5000 nM PMID: 11720854
ZINC26836972 agonist Compound 4f Ki = 980 nM EC50 = 710 nM PMID: 11720854
ZINC26837616 agonist Compound 3c Ki = 2600 nM EC50 = 3500 nM PMID: 11720854
ZINC26838000 agonist Compound 4c Ki = 158 nM EC50 = 24 nM PMID: 11720854
ZINC26838479 agonist Compound 4b Ki = 480 nM EC50 = 138 nM PMID: 11720854
ZINC26840192 agonist Compound 4d Ki = 360 nM EC50 = 390 nM PMID: 11720854
ZINC26949801 agonist Compound 17 Ki = 268 nM PMID: 12951090 PPAR_alpha
ZINC26981747 agonist Compound 4 pKi = 5.14 +/- 0.13 pEC50 = 5.52 PMID: 10612594
ZINC26990926 agonist Compound 11 pKi = 6.26 +/- 0.05 pEC50 = 5.25 +/- 0.27 PMID: 10612594
ZINC26990964 agonist Compound 3 pKi = 6.83 +/- 0.05 pEC50 = 6.51 +/- 0.24 PMID: 10612594
ZINC26993273 agonist Compound 1 pKi = 5.41 +/- 0.22 pEC50 = 5.15 +/- 0.08 PMID: 10612594
ZINC27074395 agonist Compound 12 pKi = 6.31 +/- 0.06 pEC50 = 6.47 +/- 0.19 PMID: 10612594
ZINC27095197 agonist Compound 5 EC50 = 0.15 µM PMID: 15177462
ZINC27095206 agonist Compound 7 EC50 = 2.05 µM PMID: 15177462
ZINC27101121 agonist Compound 12 EC50 = 2.11 µM PMID: 15177462 PPAR_beta
ZINC27101582 agonist Compound 14 EC50 = 0.53 µM PMID: 15177462
PPAR_alpha
ZINC27102276 agonist Compound 18 EC50 = 3.16 µM PMID: 15177462
PPAR_alpha
ZINC27103304 agonist Compound 10 EC50 = 1.5 µM PMID: 15177462
PPAR_alpha
ZINC27560473 agonist Compound 65 pKi = 6.92 +/- 0.33 PMID: 9836621
ZINC28105848 agonist Compound 2f EC50 = 295 nM PMID: 21557540
ZINC28109335 agonist Compound 28 IC50 = 4.3 µM EC50 = 1 µM PMID: 15950464 PPAR_alpha
ZINC28109342 agonist Compound 27 IC50 = 2.9 µM EC50 = 1 µM PMID: 15950464 PPAR_alpha
ZINC28111523 agonist Compound 26 IC50 = 4.3 nM EC50 = 3 µM PMID: 15950464
ZINC28116577 agonist Compound 35 IC50 = 3.7 µM EC50 = 0.5 µM PMID: 15950464 PPAR_alpha
ZINC28118861 agonist Compound 33 IC50 = 2.8 µM EC50 = 1 µM PMID: 15950464 PPAR_alpha
ZINC28120531 agonist Compound 51 IC50 = 5.8 µM EC50 = 0.7 µM PMID: 15950464 PPAR_alpha
ZINC28121066 agonist Compound 32 IC50 = 1.8 µM EC50 = 0.6 µM PMID: 15950464 PPAR_alpha
ZINC28122017 agonist Compound 45 IC50 = 2.0 µM EC50 = 0.7 µM PMID: 15950464 PPAR_alpha
ZINC28122027 agonist Compound 47 IC50 = 3.0 µM EC50 = 0.5 µM PMID: 15950464 PPAR_alpha
ZINC28123579 agonist Compound 8a EC50 = 0.11 +/- 0.02 µM PMID: 14584939
PPAR_alpha
ZINC28124682 agonist Compound 36 IC50 = 5.7 µM EC50 = 1.4 µM PMID: 15950464 PPAR_alpha
ZINC28125812 agonist Compound 7 EC50 = 0.32 +/- 0.20 µM PMID: 14584939
PPAR_alpha
ZINC28125854 agonist Compound 46 IC50 = 5.0 µM EC50 = 3 µM PMID: 15950464 PPAR_alpha
ZINC28126012 agonist Compound 52 IC50 = 4.5 µM EC50 = 1 µM PMID: 15950464 PPAR_alpha
ZINC28126520 agonist Compound 30 IC50 = 0.99 µM EC50 = 0.4 µM PMID: 15950464 PPAR_alpha
ZINC28127637 agonist Compound 1 EC50 = 8.0 µM PMID: 17379517
PPAR_alpha
ZINC28133768 agonist Compound 53 IC50 = 6.4 µM EC50 = 1 µM PMID: 15950464 PPAR_alpha
ZINC28137414 agonist Compound 54 IC50 = 0.90 µM EC50 = 0.24 µM PMID: 15950464 PPAR_alpha
ZINC28138248 agonist Compound 56 IC50 = 4.1 µM EC50 = 3 µM PMID: 15950464
ZINC28339538 agonist Compound 1e IC50 = 13 +/- 1 nM EC50 = 185 +/- 25 nM PMID: 15582409 PPAR_alpha
ZINC28345549 agonist Compound 1d IC50 = 44 +/- 9 nM EC50 = 282 +/- 29 nM PMID: 15582409 PPAR_alpha
ZINC28358143 agonist Compound 1h IC50 = 7 +/- 2 nM EC50 = 239 +/- 45 nM PMID: 15582409 PPAR_alpha
ZINC28362956 agonist Compound 1f IC50 = 5 +/- 1 nM EC50 = 305 +/- 34 nM PMID: 15582409 PPAR_alpha
ZINC28366730 agonist Compound 1g IC50 = 13 +/- 2 nM EC50 = 103 +/- 11 nM PMID: 15582409 PPAR_alpha
ZINC28369948 agonist Compound 1c IC50 = 5 +/- 1 nM EC50 = 260 +/- 20 nM PMID: 15582409 PPAR_alpha
ZINC28526217 agonist Compound 5 IC50 = 0.012 µM EC50 = 0.013 µM PMID: 16153845
ZINC28527317 agonist Compound 37 IC50 = 0.104 µM EC50 = 0.755 µM PMID: 16153845
ZINC28527476 agonist Compound 19 IC50 = 0.013 µM %max at 3µM = 45 % PMID: 16153845
ZINC28527478 agonist Compound 23 IC50 = 0.039 µM %max at 3µM = 41 % PMID: 16153845
ZINC28527497 agonist Compound 14 IC50 = 0.298 µM EC50 = 0.411 µM PMID: 16153845
ZINC28528080 agonist Compound 27 IC50 = 0.011 µM EC50 = 0.126 µM PMID: 16153845
ZINC28528081 agonist Compound 28 IC50 = 0.005 µM EC50 = 0.006 µM PMID: 16153845
ZINC28528082 agonist Compound 29 IC50 = 0.002 µM EC50 = 0.002 µM PMID: 16153845
ZINC28528119 agonist Compound 7 IC50 = 0.049 µM EC50 = 0.233 µM PMID: 16153845
ZINC28528120 agonist Compound 8 IC50 = 0.078 µM EC50 = 0.161 µM PMID: 16153845
ZINC28528173 agonist Compound 38 IC50 = 0.202 µM %max at 3µM = 29 % PMID: 16153845
ZINC28528273 agonist Compound 25 IC50 = 0.018 µM EC50 = 0.034 µM PMID: 16153845
ZINC28528348 agonist Compound 34 IC50 = 0.251 µM EC50 = 0.034 µM PMID: 16153845
ZINC28528373 agonist Compound 15 IC50 = 0.027 µM EC50 = 0.106 µM PMID: 16153845
ZINC28528407 agonist Compound 9 IC50 = 0.115 µM EC50 = 0.334 µM PMID: 16153845
ZINC28528478 agonist Compound 17 IC50 = 0.017 µM EC50 = 0.136 µM PMID: 16153845
ZINC28528484 agonist Compound 18 IC50 = 0.083 µM %max at 3µM = 53 % PMID: 16153845
ZINC28528732 agonist Compound 33 IC50 = 0.075 µM EC50 = 0.464 µM PMID: 16153845
ZINC28528833 agonist Compound 39 IC50 = 0.058 µM EC50 = 0.095 µM PMID: 16153845
ZINC28528910 agonist Compound 26 IC50 = 0.018 µM EC50 = 0.091 µM PMID: 16153845
ZINC28528918 agonist Compound 35 IC50 = 0.021 µM EC50 = 0.176 µM PMID: 16153845
ZINC28528919 agonist Compound 36 IC50 = 0.100 µM EC50 = 0.299 µM PMID: 16153845
ZINC28562958 agonist Compound 30 IC50 = 4.809 µM EC50 = 1.810 µM PMID: 16366601
ZINC28563304 agonist Compound 45a SR EC50 = 83 nM PMID: 16275080 PPAR_alpha
ZINC28563441 agonist Compound 45d SS EC50 = 30 nM PMID: 16275080 PPAR_alpha
ZINC28563467 agonist Compound 54d SS EC50 = 46 nM PMID: 16275080 PPAR_alpha
ZINC28563544 agonist Compound 3c RR EC50 = 605 nM PMID: 16275080 PPAR_alpha
ZINC28563574 agonist Compound 66d SS EC50 = 46 nM PMID: 16275080 PPAR_alpha
ZINC28563719 agonist Compound 66c RR EC50 = 225 nM PMID: 16275080 PPAR_alpha
ZINC28563761 agonist Compound 3b RS EC50 = 95 nM PMID: 16275080 PPAR_alpha
ZINC28564009 agonist Compound 3a SR EC50 = 19 nM PMID: 16275080 PPAR_alpha
ZINC28569243 agonist Compound 16a EC50 = 1900 nM PMID: 16275077
PPAR_alpha
ZINC28569401 agonist Compound 16b EC50 = 4900 nM PMID: 16275077
PPAR_alpha
ZINC28570405 agonist Compound 1a IC50 = 21 +/- 3 nM EC50 = 154 +/- 30 nM PMID: 15582409 PPAR_alpha
ZINC28635465 agonist Compound 1 EC50 = 22.6 +/- 1.6 µM PMID: 22381047 PPAR_beta
ZINC28710191 agonist Compound 22 EC50 = 407 nM PMID: 18155554
PPAR_alpha
ZINC28825459 agonist Compound 5 IC50 = 18 nM EC50 = 42 nM PMID: 18029178
PPAR_alpha
ZINC28825460 agonist Compound 6 IC50 = 9 nM EC50 = 24 nM PMID: 18029178
PPAR_alpha
ZINC28825461 agonist Compound 7 IC50 = 10 nM EC50 = 57 nM PMID: 18029178
PPAR_alpha
ZINC28825462 agonist Compound 8 IC50 = 15 nM EC50 = 49 nM PMID: 18029178
PPAR_alpha
ZINC28825463 agonist Compound 9 IC50 = 12 nM EC50 = 24 nM PMID: 18029178
PPAR_alpha
ZINC28825464 agonist Compound 10 IC50 = 12 nM EC50 = 43 nM PMID: 18029178
PPAR_alpha
ZINC28825465 agonist Compound 11 IC50 = 203 nM EC50 = 1058 nM PMID: 18029178 PPAR_beta
ZINC28825466 agonist Compound 12 IC50 = 114 nM EC50 = 479 nM PMID: 18029178
PPAR_alpha
ZINC28825467 agonist Compound 13 IC50 = 7 nM EC50 = 16 nM PMID: 18029178
PPAR_alpha
ZINC28825468 agonist Compound 14 IC50 = 7 nM EC50 = 25 nM PMID: 18029178
PPAR_alpha
ZINC28825469 agonist Compound 15 IC50 = 9 nM EC50 = 28 nM PMID: 18029178
PPAR_alpha
ZINC28825470 agonist Compound 16 IC50 = 47 nM EC50 = 10 nM PMID: 18029178
PPAR_alpha
ZINC28825471 agonist Compound 17 IC50 = 8 nM EC50 = 26 nM PMID: 18029178
PPAR_alpha
ZINC28825472 agonist Compound 18 IC50 = 20 nM EC50 = 125 nM PMID: 18029178 PPAR_beta
ZINC28825473 agonist Compound 19 IC50 = 5 nM EC50 = 24 nM PMID: 18029178
PPAR_alpha
ZINC28825474 agonist Compound 20 IC50 = 12 nM EC50 = 37 nM PMID: 18029178
PPAR_alpha
ZINC28825475 agonist Compound 21 IC50 = 17 nM EC50 = 43 nM PMID: 18029178
PPAR_alpha
ZINC28825476 agonist Compound 22 IC50 = 8 nM EC50 = 22 nM PMID: 18029178
PPAR_alpha
ZINC28825477 agonist Compound 23 IC50 = 8 nM EC50 = 28 nM PMID: 18029178
PPAR_alpha
ZINC28825478 agonist Compound 24 IC50 = 126 nM EC50 = 345 nM PMID: 18029178 PPAR_beta
ZINC28825479 agonist Compound 25 IC50 = 258 nM EC50 = 1088 nM PMID: 18029178
ZINC28825480 agonist Compound 26 IC50 = 13 nM EC50 = 25 nM PMID: 18029178
ZINC28825481 agonist Compound 27 IC50 = 233 nM EC50 = 348 nM PMID: 18029178
ZINC28825482 agonist Compound 28 IC50 = 8 nM EC50 = 32 nM PMID: 18029178
ZINC28825484 agonist Compound 29 IC50 = 37 nM EC50 = 158 nM PMID: 18029178
ZINC28825485 agonist Compound 30 IC50 = 95 nM EC50 = 238 nM PMID: 18029178
ZINC28825486 agonist Compound 31 IC50 = 98 nM EC50 = 135 nM PMID: 18029178
ZINC28825488 agonist Compound 32 IC50 = 27 nM EC50 = 24 nM PMID: 18029178
ZINC28825491 agonist Compound 33 IC50 = 35 nM EC50 = 44 nM PMID: 18029178
ZINC28825492 agonist Compound 42 IC50 = 39 nM EC50 = 116 nM PMID: 18029178
ZINC28825493 agonist Compound 43 IC50 = 50 nM EC50 = 163 nM PMID: 18029178
ZINC28890851 agonist Compound 7 IC50 = 215 nM EC50 = 836 nM PMID: 17129725 PPAR_beta
ZINC28890866 agonist Compound 8 IC50 = 568 nM EC50 = 1670 nM PMID: 17129725 PPAR_beta
ZINC28890871 agonist Compound 9 IC50 = 1090 nM EC50 = 1990 nM PMID: 17129725
PPAR_alpha
ZINC28890877 agonist Compound 10 IC50 = 940 nM EC50 = 2300 nM PMID: 17129725
PPAR_alpha
ZINC28890881 agonist Compound 11 IC50 = 46 nM EC50 = 182 nM PMID: 17129725
PPAR_alpha
ZINC28890886 agonist Compound 12 IC50 = 60 nM EC50 = 140 nM PMID: 17129725 PPAR_beta
ZINC28890891 agonist Compound 13 IC50 = 520 nM EC50 = 576 nM PMID: 17129725 PPAR_beta
ZINC28890901 agonist Compound 14 IC50 = 346 nM EC50 = 837 nM PMID: 17129725
PPAR_alpha
ZINC28890922 agonist Compound 15 IC50 = 1530 nM EC50 = 2270 nM PMID: 17129725 PPAR_beta
ZINC28890927 agonist Compound 16 IC50 = 979 nM EC50 = 1980 nM PMID: 17129725
PPAR_alpha
ZINC28890931 agonist Compound 17 IC50 = 483 nM EC50 = 696 nM PMID: 17129725 PPAR_beta
ZINC28890938 agonist Compound 18 IC50 = 88 nM EC50 = 304 nM PMID: 17129725 PPAR_beta
ZINC28890943 agonist Compound 19 IC50 = 20 nM EC50 = 67 nM PMID: 17129725
PPAR_alpha
ZINC28890948 agonist Compound 20 IC50 = 35 nM EC50 = 167 nM PMID: 17129725
PPAR_alpha
ZINC28890954 agonist Compound 21 IC50 = 16 nM EC50 = 111 nM PMID: 17129725
PPAR_alpha
ZINC28900597 agonist Compound 18 EC50 = 2.1 µM PMID: 17553678 PPAR_alpha
ZINC28900602 agonist Compound 19 EC50 = 1.1 µM PMID: 17553678 PPAR_alpha
ZINC28900607 agonist Compound 20 EC50 = 0.1 µM PMID: 17553678
PPAR_alpha
ZINC28900610 agonist Compound 21 EC50 = 5 µM PMID: 17553678
PPAR_alpha
ZINC28900634 agonist Compound 24 R EC50 = 0.91 µM PMID: 17553678
PPAR_alpha
ZINC28900640 agonist Compound 24 S EC50 = 0.87 µM PMID: 17553678
PPAR_alpha
ZINC28900750 agonist Compound 35 R EC50 = 0.94 µM PMID: 17553678
PPAR_alpha
ZINC28900755 agonist Compound 35 S EC50 = 1.19 µM PMID: 17553678
PPAR_alpha
ZINC28900759 agonist Compound 36 R EC50 = 1.10 µM PMID: 17553678
PPAR_alpha
ZINC28900764 agonist Compound 36 S EC50 = 1.31 µM PMID: 17553678
PPAR_alpha
ZINC28902543 agonist Compound 9 EC50 = 6.34 µM PMID: 17524643 PPAR_beta
ZINC28902548 agonist Compound 10 EC50 = 3.69 µM PMID: 17524643 PPAR_beta
ZINC28948386 agonist Compound 2 EC50 = 4.1 µM PMID: 17379517
PPAR_alpha
ZINC28948388 agonist Compound 3 EC50 = 0.4 µM PMID: 17379517
PPAR_alpha
ZINC28948390 agonist Compound 4 EC50 = 1.2 µM PMID: 17379517
PPAR_alpha
ZINC28948392 agonist Compound 5 EC50 = 0.2 µM PMID: 17379517
PPAR_alpha
ZINC28948394 agonist Compound 6 EC50 = 0.8 µM PMID: 17379517
PPAR_alpha
ZINC28948396 agonist Compound 7 EC50 = 0.08 µM PMID: 17379517
PPAR_alpha
ZINC28948398 agonist Compound 8 EC50 = 0.2 µM PMID: 17379517
PPAR_alpha
ZINC28948415 agonist Compound 10 EC50 = 0.19 µM PMID: 17379517 PPAR_beta
ZINC28948417 agonist Compound 11 EC50 = 3.1 µM PMID: 17379517 PPAR_alpha
ZINC28948423 agonist Compound 12 EC50 = 3.0 µM PMID: 17379517 PPAR_alpha
ZINC28948425 agonist Compound 13 EC50 = 5.1 µM PMID: 17379517 PPAR_alpha
ZINC28948431 agonist Compound 14 EC50 = 1.0 µM PMID: 17379517 PPAR_alpha
ZINC28948819 agonist Compound 9 EC50 = 0.3 µM PMID: 17379517
PPAR_alpha
ZINC28949095 agonist Compound 1a IC50 = 0.240 µM EC50 = 0.295 +/- 0.1880 µM PMID: 17292606 PPAR_alpha
ZINC28949099 agonist Compound 1b IC50 = 0.134 µM EC50 = 0.108 +/- 0.0718 µM PMID: 17292606 PPAR_alpha
ZINC28949101 agonist Compound 1c IC50 = 0.773 µM EC50 = 0.901 +/- 0.2229 µM PMID: 17292606 PPAR_alpha
ZINC28949106 agonist Compound 1d IC50 = 0.23 µM EC50 = 0.067 +/- 0.0427 µM PMID: 17292606 PPAR_alpha
ZINC28949110 agonist Compound 1e IC50 = 0.11 µM EC50 = 0.359 +/- 0.0515 µM PMID: 17292606 PPAR_alpha
ZINC28949115 agonist Compound 1f IC50 = 0.183 µM EC50 = 0.412 +/- 0.0701 µM PMID: 17292606 PPAR_alpha
ZINC28949118 agonist Compound 1g IC50 = 0.067 µM EC50 = 0.036 +/- 0.0105 µM PMID: 17292606 PPAR_alpha
ZINC28949121 agonist Compound 1h IC50 = 0.145 µM EC50= 1.39 +/- 0.4374 µM PMID: 17292606 PPAR_alpha
ZINC28949125 agonist Compound 1i IC50 = 0.540 µM EC50 = 0.759 +/- 0.3733 µM PMID: 17292606
ZINC28949139 agonist Compound 2d IC50 = 4.56 µM EC50 = 1.18 +/- 0.3394 µM PMID: 17292606
ZINC28949141 agonist Compound 2e IC50 = 3.29 µM EC50 = 0.307 +/- 0.1358 µM PMID: 17292606 PPAR_alpha
ZINC28949144 agonist Compound 2f IC50 = 0.48 µM EC50 = 0.391 +/- 0.0771 µM PMID: 17292606 PPAR_alpha
ZINC28949149 agonist Compound 2g IC50 = 0.227 µM EC50 = 0.052 +/- 0.0289 µM PMID: 17292606 PPAR_alpha
ZINC28949150 agonist Compound 2h IC50 = 0.284 µM EC50 = 0.221 +/- 0.0345 µM PMID: 17292606 PPAR_alpha
ZINC28949152 agonist Compound 2i IC50 = 0.767 µM EC50 = 0.840 +/- 0.7487 µM PMID: 17292606 PPAR_alpha
ZINC28949154 agonist Compound 2j IC50 = 1.21 µM EC50 = 1.21 +/- 0.05484 µM PMID: 17292606 PPAR_alpha
ZINC28949158 agonist Compound 2k IC50 = 2.9 µM EC50 = 0.230 +/- 0.0877 µM PMID: 17292606
ZINC28949160 agonist Compound 2l IC50 = 0.280 µM EC50 = 0.267 +/- 0.1580 µM PMID: 17292606 PPAR_alpha
ZINC28978845 agonist Compound 13 EC50 = 5.5 µM PMID: 18060776 PPAR_alpha
ZINC28978854 agonist Compound 14 EC50 = 0.5 µM PMID: 18060776
PPAR_alpha
ZINC28978856 agonist Compound 15 EC50 = 0.3 µM PMID: 18060776 PPAR_alpha
ZINC28978878 agonist Compound 33 EC50 = 84 nM PMID: 18023179
LXR_alpha
ZINC28978899 agonist Compound 37 EC50 = 40 nM PMID: 18023179
LXR_alpha
ZINC28978905 agonist Compound 38 EC50 = 69 nM PMID: 18023179
LXR_alpha
ZINC28978929 agonist Compound 20 EC50 = 0.6 µM PMID: 18060776 PPAR_alpha
ZINC29039093 agonist Compound 8 Ki = 10000 nM EC50 = 152 nM PMID: 18255290
ZINC29039095 agonist Compound 9 Ki = 10000 nM EC50 = 195 nM PMID: 18255290
ZINC29039109 agonist Compound (S) 37 Ki = 18 nM EC50 = 7.85 nM PMID: 18255290
ZINC29043827 agonist Compound 17a IC50 = 3.036 µM EC50 = 1.12 µM PMID: 18511276 PPAR_alpha
ZINC29043955 agonist Compound 15a IC50 = 7.4 µM EC50 = 4.65 µM PMID: 18511276
ZINC29045250 agonist Compound 13d IC50 = 1.32 µM EC50 = 0.18 µM PMID: 18511276 PPAR_alpha
ZINC29045403 agonist Compound 13b IC50 = 1.384 µM EC50 = 0.644 µM PMID: 18511276 PPAR_alpha
ZINC29045554 agonist Compound 31b IC50 = 0.034 µM EC50 = 0.046 µM PMID: 18511276 PPAR_alpha
ZINC29045666 agonist Compound 31a IC50 = 0.049 µM EC50 = 0.018 µM PMID: 18511276 PPAR_alpha
ZINC29046011 agonist Compound 13a IC50 = 4.51 µM EC50 = 3.86 µM PMID: 18511276 PPAR_alpha
ZINC29046131 agonist Compound 14a IC50 = 0.11 µM EC50 = 0.074 µM PMID: 18511276 PPAR_alpha
ZINC29057646 agonist Compound 75 EC50 = 815 nM PMID: 18155554
PPAR_alpha
ZINC29057808 agonist Compound 70 EC50 = 465 nM PMID: 18155554
PPAR_alpha
ZINC29058101 agonist Compound 55 EC50 = 669 nM PMID: 18155554
PPAR_alpha
ZINC29058367 agonist Compound 30 EC50 = 640 nM PMID: 18155554
PPAR_alpha
ZINC29126096 agonist Compound 3 EC50 = 0.3 µM PMID: 17964792 PPAR_alpha
ZINC29126100 agonist Compound 3 EC50 = 0.3 µM PMID: 18280733 PPAR_alpha
ZINC29126733 agonist Compound 4c EC50 = 0.3 µM PMID: 18280733 PPAR_alpha
ZINC29127122 agonist Compound 13 EC50 = 83 nM PMID: 18162399
PPAR_alpha
ZINC29127161 agonist TIPP703 EC50 = 43 nM PMID: 18162399
PPAR_alpha
ZINC29132176 agonist Compound 20 EC50 = 22.5 PMID: 18083521
PPAR_alpha
ZINC29132182 agonist Compound 18 EC50 = 7.7 PMID: 18083521
PPAR_alpha
ZINC29132184 agonist Compound 19 EC50 = 34.9 PMID: 18083521
PPAR_alpha
ZINC29132261 agonist Compound 16 EC50 = 19.4 PMID: 18083521
PPAR_alpha
ZINC29132263 agonist Compound 17 EC50 = 11.4 PMID: 18083521
PPAR_alpha
ZINC29132264 agonist Compound 14 EC50 = 17.2 PMID: 18083521
PPAR_alpha
ZINC29132266 agonist Compound 15 EC50 = 24.6 PMID: 18083521
PPAR_alpha
ZINC29132595 agonist Compound 14e EC50 = 0.01 µM PMID: 17964792 PPAR_alpha
ZINC29132642 agonist Compound 6 EC50 = 34.6 PMID: 18083521
PPAR_alpha
ZINC29132644 agonist Compound 7 EC50 = 27.6 PMID: 18083521
PPAR_alpha
ZINC29132646 agonist Compound 8 EC50 = 20.5 PMID: 18083521
PPAR_alpha
ZINC31157255 agonist Compound 2 EC50 = 48.7 +/- 6.3 µM PMID: 22381047 PPAR_beta
ZINC32207668 agonist Compound 12 EC50 = 25.3 PMID: 18083521
PPAR_alpha
ZINC33954913 agonist Compound 12/13 EC50 = 52.3 +/- 6.3 µM PMID: 22381047 PPAR_beta
ZINC34001583 agonist Compound 4 EC50 = 26.3 µM PMID: 21515063
PPAR_alpha
ZINC34049113 agonist Tak-559 imiglitazar EC50 = 0.004 µM PMID: 18976908 PPAR_alpha
ZINC34097435 agonist Compound 26 IC50 = 318 nM EC50 = 1.1 µM PMID: 16737814 PPAR_alpha
ZINC34210397 agonist Compound 28 IC50 = 139 nM EC50 = 0.16 µM PMID: 16737814
PPAR_alpha
ZINC34313754 agonist Compound (S)-2Ae IC50 = 0.003 µM EC50 = 0.023 µM PMID: 19349176 PPAR_alpha
ZINC34357149 agonist Compound (S)-2Ca IC50 = 0.002 µM EC50 = 0.004 µM PMID: 19349176 PPAR_alpha
ZINC34357232 agonist Compound 25b EC50 = 0.86 +/- 0.01 µM PMID: 17243659 PPAR_alpha
ZINC34395734 agonist Compound 14d EC50 = 0.54 µM PMID: 22197396
ZINC34443936 agonist Compound 28 EC50 = 0.310 µM PMID: 18947994 PPAR_alpha
ZINC34471017 agonist Compound 13 IC50 = 11 nM EC50 = 12 +/- 4 nM PMID: 17005393 PPAR_alpha
ZINC34638474 agonist Compound 1 Ki = 18 nM EC50 = 7.85 nM PMID: 19376700 PPAR_alpha
ZINC34717672 agonist Compound 27 IC50 = 399 nM EC50 = 2.0 µM PMID: 16737814
PPAR_alpha
ZINC34717674 agonist Compound 22 IC50 = 38 nM EC50 = 0.04 µM PMID: 16737814 PPAR_alpha
ZINC34717676 agonist Compound 12 IC50 = 316 nM EC50 = 0.99 µM PMID: 16737814 PPAR_alpha
ZINC34717680 agonist Compound 17 IC50 = 377 nM EC50 = 0.77 µM PMID: 16737814 PPAR_alpha
ZINC34717682 agonist Compound 7 IC50 = 178 nM EC50 = 0.28 µM PMID: 16737814 PPAR_alpha
ZINC34717685 agonist Compound 20 IC50 = 13 nM EC50 = 0.12 µM PMID: 16737814 PPAR_alpha
ZINC34717687 agonist Compound 21 IC50 = 15 nM EC50 = 0.18 M PMID: 16737814 PPAR_alpha
ZINC34717689 agonist Compound 16 IC50 = 24 nM EC50 = 0.06 µM PMID: 16737814 PPAR_alpha
ZINC34717691 agonist Compound 23 IC50 = 71 nM EC50 = 0.07 µM PMID: 16737814 PPAR_alpha
ZINC34717695 agonist Compound 29 IC50 = 223 nM EC50 = 0.06 µM PMID: 16737814 PPAR_alpha
ZINC34717697 agonist Compound 19 IC50 = 27 nM EC50 = 0.19 µM PMID: 16737814 PPAR_alpha
ZINC34717698 agonist Compound 11 IC50 = 196 nM EC50 = 0.80 µM PMID: 16737814 PPAR_alpha
ZINC34717700 agonist Compound 18 IC50 = 61 +/- 0 nM EC50 = 355 +/- 87 nM PMID: 16970391
PPAR_alpha
ZINC34717701 agonist Compound 6 IC50 = 38 +/- 0 nM EC50 = 112 +/- 11 nM PMID: 16970391
PPAR_alpha
ZINC34717702 agonist Compound 17 IC50 = 6 +/- 1 nM EC50 = 4 +/- 0 nM PMID: 16970391
PPAR_alpha
ZINC34717703 agonist Compound 19 IC50 = 63 +/- 6 nM EC50 = 402 +/- 0 nM PMID: 16970391
PPAR_alpha
ZINC34717704 agonist Compound 20 IC50 = 19 +/- 2 nM EC50 = 102 +/- 16 nM PMID: 16970391
PPAR_alpha
ZINC34717709 agonist Compound 13 IC50 = 59 +/- 0 EC50 = 228 +/- 17 nM PMID: 16970391
PPAR_alpha
ZINC34717711 agonist Compound 15 IC50 = 15 +/- 1 nM EC50 = 52 +/- 8 nM PMID: 16970391
PPAR_alpha
ZINC34717712 agonist Compound 16 IC50 = 6 +/- 0 nM EC50 = 5 +/- 1 nM PMID: 16970391
PPAR_alpha
ZINC34717743 agonist Compound 11 Ki = 5.1 µM EC50 = 0.984 µM PMID: 16973358 PPAR_alpha
ZINC34717744 agonist Compound 12 Ki = 0.063 µM EC50 = 0.013 µM PMID: 16973358 PPAR_alpha
ZINC34717746 agonist Compound 13 Ki = 0.15 µM EC50 = 0.006 µM PMID: 16973358 PPAR_alpha
ZINC34717748 agonist Compound 14 S Ki = 0.27 µM EC50 = 0.110 µM PMID: 16973358 PPAR_alpha
ZINC34717750 agonist Compound 13 S Ki = 0.043 µM EC50 = 0.026 µM PMID: 16979341 PPAR_alpha
ZINC34717751 agonist Compound 36 Ki = 0.015 µM EC50 = 0.05 µM PMID: 16973358 PPAR_alpha
ZINC34717755 agonist Compound 14 IC50 = 21 nM EC50 = 3 +/- 0.37 nM PMID: 17005393
ZINC34717756 agonist Compound 15 IC50 = 95 +/- 27 nM EC50 = 115 +/- 20 nM PMID: 17005394 PPAR_alpha
ZINC34717757 agonist Compound 16 Ki = 7.98 µM EC50 = 1.01 µM PMID: 16973358 PPAR_alpha
ZINC34717758 agonist Compound 17 IC50 = 33 +/- 2 nM EC50 = 9 +/- 0.41 nM PMID: 17005393
ZINC34717759 agonist Compound 16 IC50 = 706 +/- 188 nM EC50 = 2684 +/- 34 nM PMID: 17005394
ZINC34717760 agonist Compound 17 Ki = 0.394 µM EC50 = 0.125 µM PMID: 16973358 PPAR_alpha
ZINC34717761 agonist Compound 17 IC50 = 161 +/- 32 nM EC50 = 1019 +/- 186 nM PMID: 17005394 PPAR_alpha
ZINC34717762 agonist Compound 15 IC50 = 24 +/- 1.4 nM EC50 = 77 +/- 12 nM PMID: 17005393 PPAR_alpha
ZINC34717763 agonist Compound 16 IC50 = 17 +/- 2 nM EC50 = 8 +/- 2 nM PMID: 17005393 PPAR_alpha
ZINC34717765 agonist Compound 18 IC50 = 72 +/- 22 nM EC50 = 527 +/- 64 nM PMID: 17005394 PPAR_alpha
ZINC34717766 agonist Compound 19 IC50 = 26 +/- 6 nM EC50 = 8 +/- 2 nM PMID: 17005394 PPAR_alpha
ZINC34717767 agonist Compound 37 IC50 = 26 +/- 15 nM EC50 = 2 +/- 0.3 nM PMID: 17005394 PPAR_alpha
ZINC34717768 agonist Compound 19 S Ki = 0.006 µM EC50 = 0.014 µM PMID: 16973358 PPAR_alpha
ZINC34717770 agonist Compound 33 IC50 = 47 +/- 16 nM EC50 = 19 +/- 10 nM PMID: 17005394 PPAR_alpha
ZINC34717771 agonist Compound 21 Ki = 0.081 µM EC50 = 0.209 µM PMID: 16973358 PPAR_alpha
ZINC34717773 agonist Compound 34 IC50 = 50 +/- 27 nM EC50 = 2 +/- 1 nM PMID: 17005394 PPAR_alpha
ZINC34717779 agonist Compound 35 IC50 = 50 +/- 21 nM EC50 = 4 +/- 1 nM PMID: 17005394 PPAR_alpha
ZINC34717782 agonist Compound 27 Ki = 0.023 µM EC50 = 0.022 µM PMID: 16973358 PPAR_alpha
ZINC34717784 agonist Compound 28 Ki = 0.016 µM EC50 = 0.005 µM PMID: 16973358 PPAR_alpha
ZINC34717786 agonist Compound 36 IC50 = 17 +/- 5 nM EC50 = 7 +/- 1 nM PMID: 17005394 PPAR_alpha
ZINC34717787 agonist Compound 38 IC50 = 22 +/- 1 nM EC50 = 28 +/- 6 nM PMID: 17005394 PPAR_alpha
ZINC34717788 agonist Compound 29 Ki = 0.052 µM EC50 = 0.042 µM PMID: 16973358 PPAR_alpha
ZINC34717790 agonist Compound 30 Ki = 0.011 µM EC50 = 0.001 µM PMID: 16973358 PPAR_alpha
ZINC34717794 agonist Compound 31 Ki = 0.094 µM EC50 = 0.006 µM PMID: 16973358 PPAR_alpha
ZINC34717798 agonist Compound 5 Ki = 2.1 µM EC50 = 0.268 µM PMID: 16973358 PPAR_alpha
ZINC34717802 agonist Compound 33 Ki = 0.017 µM EC50 = 0.005 µM PMID: 16973358 PPAR_alpha
ZINC34717804 agonist Compound 6 Ki = 1.1 µM EC50 = 0.065 µM PMID: 16973358 PPAR_alpha
ZINC34717806 agonist Compound 7 Ki = 0.24 µM EC50 = 0.454 µM PMID: 16973358 PPAR_alpha
ZINC34717810 agonist Compound 8 Ki = 8.8 µM EC50 = 1.28 µM PMID: 16973358 PPAR_alpha
ZINC34717812 agonist Compound 34 Ki = 0.007 µM EC50 = 0.002 µM PMID: 16973358 PPAR_alpha
ZINC34717818 agonist Compound 9 Ki = 0.36 µM EC50 = 1.65 µM PMID: 16973358 PPAR_alpha
ZINC34717820 agonist Compound 35 Ki = 0.334 µM EC50 = 0.028 µM PMID: 16973358 PPAR_alpha
ZINC34717824 agonist Compound 2b IC50 = 2.30 µM EC50 = 0.136 +/- 0.0821 µM PMID: 17292606 PPAR_alpha
ZINC34867419 agonist Compound 28 EC50 = 1582 nM PMID: 16797985
PPAR_alpha
ZINC34875784 agonist Compound 18 EC50 = 0.028 µM PMID: 18826205 PPAR_alpha
ZINC34884343 agonist Compound 50 EC50 = 0.14 µM PMID: 20527969
ZINC35065299 agonist Compound 9 EC50 = 3.470 µM PMID: 17034149
PPAR_alpha
ZINC35246678 agonist Compound 14 EC50 = 1.87 +/- 0.79 µM PMID: 17243659
PPAR_alpha
ZINC35819842 agonist Compound 41 EC50 = 0.55 µM PMID: 20527969
ZINC35999854 agonist Compound 53 IC50 = 0.185 µM EC50 = 0.140 µM PMID: 18394907 PPAR_alpha
ZINC36184624 agonist Compound 39 PMID: 16290140
ZINC36184625 agonist Compound 37 PMID: 16290140
ZINC36184626 agonist Compound 30 PMID: 16290140
ZINC36184627 agonist Compound 34 PMID: 16290140
ZINC36184765 agonist Compound 35 PMID: 16290140
ZINC36184766 agonist Compound 38 PMID: 16290140
ZINC36184767 agonist Compound 40 PMID: 16290140
ZINC36184768 agonist Compound 31 PMID: 16290140
ZINC36294914 agonist Compound 4 PMID: 19374389
ZINC36757774 agonist Compound 23 Ki = 10 nM EC50 = 4 nM PMID: 11677135
PPAR_alpha
ZINC36757865 agonist Compound 23 EC50 = 153 nM PMID: 16797985
PPAR_alpha
ZINC36757866 agonist Compound 22 EC50 = 1261 nM PMID: 16797985
PPAR_alpha
ZINC36757867 agonist Compound 21 EC50 = 1185 nM PMID: 16797985
PPAR_alpha
ZINC36757868 agonist Compound 16 EC50 = 757 nM PMID: 16797985
PPAR_alpha
ZINC36757869 agonist Compound 5 EC50 = 288 nM PMID: 16797985
PPAR_alpha
ZINC36757870 agonist Compound 7 EC50 = 4.220 µM PMID: 17034149 PPAR_alpha
ZINC36757871 agonist Compound 12 EC50 = 0.470 µM PMID: 17034149
PPAR_alpha
ZINC36757872 agonist Compound 11 EC50 = 0.650 µM PMID: 17034149 PPAR_alpha
ZINC36757873 agonist Compound 15 Ki = 14.4 µM EC50 = 2.81 µM PMID: 16973358 PPAR_alpha
ZINC36757875 agonist GW501516 EC50 = 8.900 +/- 0.27 µM PMID: 17243659
ZINC36757876 agonist Compound 45 EC50 = 0.73 +/- 0.12 µM PMID: 17243659
PPAR_alpha
ZINC38139028 agonist Compound 10 Ki = 0.30 µM EC50 = 3.0 µM PMID: 19464171
PPAR_alpha
ZINC38158119 agonist Compound 8b EC50 = 1.65 +/- 0.025 µM PMID: 14584939
PPAR_alpha
ZINC38310496 agonist Compound 30 EC50 = 0.020 µM PMID: 18947994
PPAR_alpha
ZINC38320570 agonist Compound 8 EC50 = 0.05 µM PMID: 18947994
PPAR_alpha
ZINC38323523 agonist Compound 25 EC50 = 0.025 µM PMID: 18947994
PPAR_alpha
ZINC38323742 agonist Compound 15 EC50 = 0.069 µM PMID: 18947994 PPAR_alpha
ZINC38336531 agonist Compound 26 EC50 = 0.03 µM PMID: 18947994 PPAR_alpha
ZINC38362582 agonist Compound 15 EC50 = 0.9 µM PMID: 19301897 PPAR_alpha
ZINC38383390 agonist Compound 14g EC50 = 0.16 µM PMID: 22197396
ZINC38396199 agonist Compound 17e IC50 = 0.145 µM EC50 = 0.065 µM PMID: 19783444 PPAR_alpha
ZINC38401704 agonist Compound 14b EC50 = 0.12 µM PMID: 22197396
ZINC38448923 agonist Compound 66 IC50 = 1.6 µM EC50 = 0.480 µM PMID: 18394907 PPAR_alpha
ZINC38471554 agonist Compound 14c EC50 = 0.67 µM PMID: 22197396 PPAR_alpha
ZINC38473671 agonist Compound 14i EC50 = 0.03 µM PMID: 22197396
ZINC38846715 antagonist metaglidasen IC50 = 0,22 µM PMID: 18329752
ZINC40164580 antagonist CPA PMID: 20816085
ZINC40331238 agonist Compound 54 IC50 = 3.1 µM EC50 = 2.3 µM PMID: 18394907 PPAR_alpha
ZINC40379438 agonist Compound 7f IC50 = 4 nM EC50 = 2 nM PMID: 18701276
ZINC40379545 agonist Compound 7d IC50 = 10 nM EC50 = 3 nM PMID: 18701276
ZINC40379961 agonist Compound 12 EC50 = 0.030 µM PMID: 18947994
PPAR_alpha
ZINC40380487 agonist Compound 10 EC50 = 0.05 µM PMID: 18947994
PPAR_alpha
ZINC40380643 agonist Compound 7e IC50 = 16 nM EC50 = 9 nM PMID: 18701276
ZINC40391278 agonist Compound 16 EC50 = 0.303 µM PMID: 18947994
PPAR_alpha
ZINC40392603 agonist Compound 7h IC50 = 1 nM EC50 = 1 nM PMID: 18701276
ZINC40392616 agonist Compound 14 EC50 = 0.06 µM PMID: 18947994
PPAR_alpha
ZINC40392844 agonist Compound 12e IC50 = 3 nM EC50 = 4 nM PMID: 18701276
ZINC40393680 agonist Compound 7g IC50 = 2 nM EC50 = 1 nM PMID: 18701276
ZINC40393697 agonist Compound 12g IC50 = 3 nM EC50 = 4 nM PMID: 18701276
ZINC40393734 agonist Compound 6 EC50 = 0.03 µM PMID: 18947994
PPAR_alpha
ZINC40395284 agonist Compound 13i EC50 = 5.01 µM PMID: 18625559 PPAR_alpha
ZINC40395377 agonist Compound 13a EC50 = 0.096 µM PMID: 18625559 PPAR_alpha
ZINC40395577 agonist Compound 13f EC50 = 0.0198 µM PMID: 18625559 PPAR_alpha
ZINC40395608 agonist Compound 13d EC50 = 1.385 µM PMID: 18625559 PPAR_alpha
ZINC40403829 agonist Compound 23 EC50 = 0.028 µM PMID: 18947994 PPAR_alpha
ZINC40403979 agonist Compound 36 IC50 = 12 µM EC50 = 0.492 µM PMID: 18394907
ZINC40404464 agonist Compound 60 IC50 = 11 µM EC50 = 3.6 µM PMID: 18394907
ZINC40404981 agonist Compound (S)-5b EC50 = 0.639 µM PMID: 18771917 PPAR_alpha
ZINC40405720 agonist Compound (S)-28 EC50 = 0.049 +/- 0.003 µM PMID: 18835719 PPAR_alpha
ZINC40405740 agonist Compound 33 IC50 = 12 µM EC50 = 2 µM PMID: 18394907
ZINC40406108 agonist Compound (R)-27 EC50 = 0.70 +/- 0.02 µM PMID: 18835719 PPAR_alpha
ZINC40409323 agonist Compound 28 IC50 = 0.293 µM EC50 = 0.173 µM PMID: 18394907 PPAR_alpha
ZINC40410758 agonist Compound (S)-3Bb IC50 = 0.027 µM EC50 = 0.021 µM PMID: 19349176 PPAR_alpha
ZINC40412686 agonist Compound (S)-2Ga IC50 = 0.002 µM EC50 = 0.032 µM PMID: 19349176 PPAR_alpha
ZINC40413241 agonist Compound (S)-4Ba IC50 = 0.013 µM EC50 = 0.007 µM PMID: 19349176 PPAR_alpha
ZINC40413451 agonist Compound (S)-2Bb IC50 = 0.017 µM EC50 = 0.009 µM PMID: 19349176 PPAR_alpha
ZINC40420188 agonist Compound 20 EC50 = 0.015 µM PMID: 18976908 PPAR_alpha
ZINC40420651 agonist Compound (S)-2Ab IC50 = 0.023 µM EC50 = 0.053 µM PMID: 19349176 PPAR_alpha
ZINC40421027 agonist Compound 9b EC50 = 0.56 µM PMID: 18976908 PPAR_alpha
ZINC40421120 agonist Compound 32 EC50 = 1.89 µM PMID: 18826205
ZINC40422975 agonist Compound (S)-5r EC50 = 0.862 µM PMID: 18771917 PPAR_alpha
ZINC40423420 agonist Compound 17 EC50 = 0.139 µM PMID: 18826205 PPAR_alpha
ZINC40423527 agonist Compound S-4 EC50 = 0.40 +/- 0.20 µM PMID: 19775169 PPAR_alpha
ZINC40423842 agonist Compound (R)-1 EC50 = 5.93 +/- 2.60 µM PMID: 19053776
ZINC40752932 agonist Compound 14d Kd = 8.69 µM RU = 3.529 µM PMID: 17010604
ZINC40834180 agonist Compound 7b Transactiv. = 2.1 PMID: 18805005 PPAR_beta
ZINC40835840 agonist Compound 12b IC50 = 54 nM EC50 = 156 nM PMID: 18701276
ZINC40836031 agonist Compound 7a IC50 = 726 nM EC50 = 2926 nM PMID: 18701276
ZINC40845182 agonist Compound 12a IC50 = 25 nM EC50 = 36 nM PMID: 18701276
ZINC40846737 agonist Compound 12c IC50 = 106 nM EC50 = 140 nM PMID: 18701276
ZINC40847207 agonist Compound 4 EC50 = 1.0 µM PMID: 18947994
PPAR_alpha
ZINC40860536 agonist Compound 7b IC50 = 66 nM EC50 = 27 nM PMID: 18701276
ZINC40860538 agonist Compound 7c IC50 = 5 nM EC50 = 3 nM PMID: 18701276
ZINC40864828 agonist Compound 7i IC50 = 2 nM EC50 = 2 nM PMID: 18701276
ZINC40865738 agonist Compound 12d IC50 = 15 nM EC50 = 4 nM PMID: 18701276
ZINC40865740 agonist Compound 12f IC50 = 23 nM EC50 = 94 nM PMID: 18701276
ZINC40866291 agonist Compound 8c max. activation = 22 % at 10 µM PMID: 20503989
ZINC40866293 agonist Compound 8d EC50 = 10.4 +/- 0.4 µM PMID: 20503989
ZINC40866358 agonist Compound 17 EC50 = 0.478 µM PMID: 18947994 PPAR_alpha
ZINC40866603 agonist Compound 20 EC50 = 0.190 µM PMID: 18947994
ZINC40872869 agonist Compound 5 EC50 = 0.270 µM PMID: 18947994 PPAR_alpha
ZINC40876346 agonist Compound 13g EC50 = 0.239 µM PMID: 18625559 PPAR_alpha
ZINC40879926 agonist Compound 13c EC50 = 4.096 µM PMID: 18625559 PPAR_alpha
ZINC40891654 agonist Compound 29 EC50 = 0.110 µM PMID: 18947994
PPAR_alpha
ZINC40892620 agonist Compound (S)-30 EC50 = 0.42 +/- 0.02 µM PMID: 18835719 PPAR_alpha
ZINC40899427 agonist Compound 22 EC50 = 0.130 µM PMID: 18947994
ZINC40901427 agonist Compound 21 EC50 = 0.176 µM PMID: 18947994
ZINC40913431 agonist Compound (S)-29 EC50 = 0.065 +/- 0.004 µM PMID: 18835719 PPAR_alpha
ZINC40914459 agonist Compound 24 EC50 = 0.080 µM PMID: 18947994
ZINC40914961 agonist Compound (S)-27 EC50 = 0.027 +/- 0.003 µM PMID: 18835719 PPAR_alpha
ZINC40915578 agonist Compound 40 IC50 = 0.255 µM EC50 = 0.102 µM PMID: 18394907
ZINC40915868 agonist Compound 59 IC50 = 28 µM EC50 = 1.2 µM PMID: 18394907
ZINC40918915 agonist Compound 41 IC50 = 2.6 µM EC50 = 2.6 µM PMID: 18394907
ZINC40918916 agonist Compound 44 IC50 = 2 µM EC50 = 3.7 µM PMID: 18394907
ZINC40934024 agonist Compound 13a EC50 = 0.43 µM PMID: 18976908 PPAR_alpha
ZINC40934025 agonist Compound 13b EC50 = 0.031 µM PMID: 18976908 PPAR_alpha
ZINC40934174 agonist Compound 13c EC50 = 0.1 µM PMID: 18976908 PPAR_alpha
ZINC40936783 agonist Compound 9c EC50 = 0.45 µM PMID: 18976908 PPAR_alpha
ZINC40937335 agonist Compound (S)-4Aa IC50 = 0.011 µM EC50 = 0.033 µM PMID: 19349176 PPAR_alpha
ZINC40937683 agonist Compound (S)-2Gd IC50 = 0.005 µM EC50 = 0.010 µM PMID: 19349176 PPAR_alpha
ZINC40938791 agonist Compound (S)-2Bf IC50 = 0.003 µM EC50 = 0.431 µM PMID: 19349176 PPAR_alpha
ZINC40939033 agonist Compound (S)-2Fa IC50 = 0.003 µM EC50 = 0.151 µM PMID: 19349176 PPAR_alpha
ZINC40939173 agonist Compound 24 EC50 = 0.175 µM PMID: 18826205 PPAR_alpha
ZINC40939498 agonist Compound 23 EC50 = 1.61 µM PMID: 18826205 PPAR_alpha
ZINC40939500 agonist Compound 25 EC50 = 0.279 µM PMID: 18826205 PPAR_alpha
ZINC40940265 agonist Compound (S)-2Ac IC50 = 0.008 µM EC50 = 0.011 µM PMID: 19349176
ZINC40940331 agonist Compound (S)-3Ba IC50 = 0.036 µM EC50 = 0.037 µM PMID: 19349176 PPAR_alpha
ZINC40940615 agonist Compound (S)-2Ad IC50 = 0.002 µM EC50 = 0.010 µM PMID: 19349176 PPAR_alpha
ZINC40950621 agonist Compound 16 EC50 = 0.121 µM PMID: 18826205 PPAR_alpha
ZINC40950913 agonist Compound 2 IC50 = 44 µM PMID: 18821746
ZINC40950935 agonist Compound 84 EC50 = 3.29 µM PMID: 18826205 PPAR_alpha
ZINC40951015 agonist Compound 19 EC50 = 0.036 µM PMID: 18826205 PPAR_alpha
ZINC40951018 agonist Compound 21 EC50 = 0.046 µM PMID: 18826205 PPAR_alpha
ZINC40951694 agonist Compound 4 EC50 = 1.07 µM PMID: 19301897
ZINC40952198 agonist Compound 85 EC50 = 37.4 µM PMID: 18826205 PPAR_alpha
ZINC40975334 agonist Compound 37 Ki = 0.11 µM EC50= 0.39 µM PMID: 19464171 PPAR_beta
ZINC40976206 agonist Compound 35 Ki = 0.20 µM EC50= 1.5 µM PMID: 19464171
ZINC40976208 agonist Compound 36 Ki = 0.076 µM EC50= 0.50 µM PMID: 19464171 PPAR_beta
ZINC40979112 agonist Compound 7e Transactiv. = 2.2 PMID: 18805005 PPAR_beta
ZINC40979174 agonist Compound 20 EC50 = 0.040 µM PMID: 18826205 PPAR_alpha
ZINC42804043 agonist Compound 11 EC50 = 0.12 µM PMID: 19301897 PPAR_alpha
ZINC42804863 agonist Compound 20 Ki = 0.077 µM EC50= 0.70 µM PMID: 19464171 PPAR_beta
ZINC42804868 agonist Compound 21 Ki = 0.033 µM EC50= 0.16 µM PMID: 19464171 PPAR_beta
ZINC42804942 agonist Compound 25 Ki = 0.079 µM EC50= 3.3 µM PMID: 19464171 PPAR_beta
ZINC42807188 agonist Compound 26 Ki = 0.020 µM EC50= 0.61 µM PMID: 19464171 PPAR_beta
ZINC42807859 agonist Compound 33 Ki = 0.084 µM EC50= 0.49 µM PMID: 19464171 PPAR_beta
ZINC42833889 agonist Compound 8 EC50 = 0.51 µM PMID: 19301897 PPAR_alpha
ZINC42833932 agonist Compound (S)-3Ff IC50 = 0.008 µM EC50 = 0.038 µM PMID: 19349176 PPAR_alpha
ZINC42834179 agonist Compound 19 EC50 = 0.05 µM PMID: 19301897 PPAR_alpha
ZINC42834793 agonist Compound 28 Ki = 0.025 µM EC50= 1.6 µM PMID: 19464171 PPAR_beta
ZINC42835651 agonist Compound 22 Ki = 0.0842 µM EC50= 2.2 µM PMID: 19464171 PPAR_beta
ZINC42851344 agonist Compound 29 EC50 = 4000 nM PMID: 19275963 PPAR_beta
ZINC42851547 agonist Compound 27 Ki = 0.044 µM EC50= 1.4 µM PMID: 19464171 PPAR_beta
ZINC42875255 agonist Compound (S)-4l EC50 = 38 +/- 3 nM PMID: 18662876
PPAR_alpha
ZINC42875604 agonist Compound 19 EC50 = 1.7 µM PMID: 18947994 PPAR_alpha
ZINC42876236 agonist Compound 12h IC50 = 22 nM EC50 = 23 nM PMID: 18701276
ZINC42887754 agonist Compound 18 EC50 = 60 nM PMID: 19275963
ZINC42890104 agonist Compound 5 IC50 = 1 nM EC50 = 3 nM PMID: 19507861
ZINC42890929 agonist Compound 7d Transactiv. = 1.2 PMID: 18805005 PPAR_beta
ZINC42890958 agonist Compound 6 EC50 = 0.43 µM PMID: 19301897 PPAR_alpha
ZINC42920692 agonist Compound 23 Ki = 0.21 µM EC50= 5.9 µM PMID: 19464171 PPAR_beta
ZINC42921106 agonist Compound 25 EC50 = 13.8 +/- 3.4 µM PMID: 19556125
PPAR_alpha
ZINC42965122 agonist Compound 3c Ki = 254 nM EC50 = 7.52 nM PMID: 19376700 PPAR_alpha
ZINC42966524 agonist Compound 8b Ki = 33 nM EC50 = 125 nM PMID: 19376700
ZINC43009893 agonist Compound 12g IC50 = 17 nM EC50 = 21 nM PMID: 19530681 PPAR_alpha
ZINC43009896 agonist Compound 12h IC50 = 10 nM EC50 = 2 nM PMID: 19530681 PPAR_alpha
ZINC43009976 agonist Compound 12c IC50 = 4 nM EC50 = 6 nM PMID: 19530681
ZINC43009979 agonist Compound 12d IC50 = 9 nM EC50 = 2 nM PMID: 19530681 PPAR_alpha
ZINC43011343 agonist Compound 12e IC50 = 8 nM EC50 = 1 nM PMID: 19530681
ZINC43011346 agonist Compound 12f IC50 = 12 nM EC50 = 10 nM PMID: 19530681
ZINC43019982 agonist Compound 1 IC50 = 1 nM EC50 = 3 nM PMID: 19530681
ZINC43022184 agonist Compound 21 EC50 = 0.60 +/- 0.12 µM PMID: 19556125
PPAR_alpha
ZINC43060453 agonist Compound (S)-11 EC50 = 1.7 +/- 0.18 µM PMID: 19556125 PPAR_alpha
ZINC43060456 agonist Compound (R)-11 EC50 = 0.011 +/- 0.004 µM PMID: 19556125 PPAR_alpha
ZINC43062887 agonist Compound 5 PMID: 19374389
ZINC43065700 agonist Compound 3b Ki = 18.4 nM EC50 = 7 nM PMID: 19376700 PPAR_alpha
ZINC43068539 agonist Compound 27 EC50 = 1.5 +/- 0.25 µM PMID: 19556125 PPAR_alpha
ZINC43075668 agonist Compound 2 IC50 = 2 nM EC50 = 2 nM PMID: 19530681
ZINC43078296 agonist Compound 12k IC50 = 16 nM EC50 = 12 nM PMID: 19530681 PPAR_alpha
ZINC43078627 agonist Compound 3a Ki = 54.2 nM EC50 = 13 nM PMID: 19376700 PPAR_alpha
ZINC43129949 agonist Compound 32 EC50 = 1.6 µM PMID: 20527969
ZINC43200300 agonist Compound 2a EC50 = 9193 nM PMID: 20356736 PPAR_alpha
ZINC43200301 agonist Compound 2l EC50 = 3443 nM PMID: 20356736 PPAR_alpha
ZINC43200302 agonist Compound 2s EC50 = 772 nM PMID: 20356736 PPAR_alpha
ZINC43206884 agonist Compound 33 pEC50 = 8.2 PMID: 21798739
ZINC43640915 agonist Compound 5 EC50 = 8.5 PMID: 18083521
PPAR_alpha
ZINC44280935 agonist Compound 20 EC50 = 30 nM PMID: 19275963
PPAR_alpha
ZINC44281357 agonist Compound 12 EC50 = 0.3 µM PMID: 19301897 PPAR_alpha
ZINC44305553 agonist Compound 10 EC50 = 2.8 µM PMID: 19301897 PPAR_alpha
ZINC44350697 agonist Compound 9 EC50 = 0.37 µM PMID: 19301897 PPAR_alpha
ZINC44351563 agonist Compound 7 EC50 = 2.12 µM PMID: 19301897
ZINC44351663 agonist Compound 17 EC50 = 0.1 µM PMID: 19301897 PPAR_alpha
ZINC44351719 agonist Compound 13 IC50 = 1 nM EC50 = 1 nM PMID: 18701276
ZINC44351925 agonist Compound 18 EC50 = 0.54 µM PMID: 19301897 PPAR_alpha
ZINC44352081 agonist Compound 5 EC50 = 2.07 µM PMID: 19301897
ZINC44352339 agonist Compound 2 EC50 = 3.5 µM PMID: 19301897 PPAR_alpha
ZINC44359368 agonist Compound (R)-4l EC50 = 160 +/- 10 nM PMID: 18662876
PPAR_alpha
ZINC44418541 agonist Compound 28 EC50 = 2000 nM PMID: 19275963 PPAR_alpha
ZINC44460340 agonist Compound 12 IC50 = 1321 nM EC50 = 2789.0 nM PMID: 20218621 PPAR_alpha
ZINC44460341 agonist Compound 1 EC50 = 4017 nM PMID: 20356736 PPAR_alpha
ZINC45284041 agonist Compound R-2 EC50 = 5.7 +/- 0.4 µM PMID: 19775169 PPAR_alpha
ZINC45287096 agonist Compound R-4 EC50 = 1.6 +/- 0.3 µM PMID: 19775169
ZINC45335524 agonist Compound 9d EC50 = 1.1 µM PMID: 20022492 PPAR_alpha
ZINC45335620 agonist Compound 9i EC50 = 0.2 µM PMID: 20022492 PPAR_alpha
ZINC45335809 agonist Compound 9e EC50 = 1.4 µM PMID: 20022492 PPAR_alpha
ZINC45335818 agonist Compound 9f EC50 = 1.9 µM PMID: 20022492 PPAR_alpha
ZINC45336592 agonist Compound 9n EC50 = 0.7 µM PMID: 20022492 PPAR_alpha
ZINC45338002 agonist Compound 9b EC50 = 1.4 µM PMID: 20022492 PPAR_alpha
ZINC45338533 agonist Compound 9g EC50 = 0.2 µM PMID: 20022492 PPAR_alpha
ZINC45338535 agonist Compound 9h EC50 = 0.1 µM PMID: 20022492 PPAR_alpha
ZINC45339287 agonist Compound 9j EC50 = 0.2 µM PMID: 20022492 PPAR_alpha
ZINC45339289 agonist Compound 9k EC50 = 0.8 µM PMID: 20022492 PPAR_alpha
ZINC45339291 agonist Compound 9l EC50 = 1.0 µM PMID: 20022492 PPAR_alpha
ZINC45375227 agonist Compound 9m EC50 = 1.6 µM PMID: 20022492 PPAR_alpha
ZINC45386701 agonist Compound 9c EC50 = 2.1 µM PMID: 20022492 PPAR_alpha
ZINC45495691 agonist Compound 11 Transactiv. = 1.4 PMID: 18805005 PPAR_beta
ZINC45496383 agonist Compound 7a Transactiv. = 1.5 PMID: 18805005 PPAR_beta
ZINC45497234 agonist Compound 22 EC50 = 2.94 µM PMID: 18826205 PPAR_alpha
ZINC45497359 agonist Compound 7g Transactiv. = 2.2 PMID: 18805005 PPAR_beta
ZINC45505696 agonist Compound 13 EC50 = 0.42 µM PMID: 19301897
PPAR_alpha
ZINC45506275 agonist Compound 16 EC50 = 0.47 µM PMID: 19301897
PPAR_alpha
ZINC45506726 agonist Compound 7c Transactiv. = 1.9 PMID: 18805005 PPAR_beta
ZINC49048575 agonist Compound 2o EC50 = 4018 nM PMID: 20356736 PPAR_alpha
ZINC49049505 agonist Compound 2j EC50 = 20690 nM PMID: 20356736 PPAR_alpha
ZINC49049976 agonist Compound 2m EC50 = 9288 nM PMID: 20356736 PPAR_alpha
ZINC49054253 agonist Compound 2q EC50 = 1692 nM PMID: 20356736 PPAR_alpha
ZINC49054256 agonist Compound 2r EC50 = 571 nM PMID: 20356736 PPAR_alpha
ZINC49066669 agonist Compound 19 IC50 = 2300 nM EC50 = 1007 nM PMID: 20218621
ZINC49067577 agonist Compound 23 IC50 = 7257 nM EC50 = 3445 nM PMID: 20218621 PPAR_alpha
ZINC49067579 agonist Compound 24 IC50 = 873 nM EC50 = 1124 nM PMID: 20218621 PPAR_alpha
ZINC49068395 agonist Compound 13 IC50 = 3546 nM EC50 = 2901 nM PMID: 20218621 PPAR_alpha
ZINC49069136 agonist Compound 1b EC50 = 10.56 +/- 2.18 µM PMID: 21450468 PPAR_alpha
ZINC49069520 agonist Compound 1c EC50 = 50.22 +/- 4.12 µM PMID: 21450468
ZINC49070602 agonist Compound 25 IC50 = 1361 nM EC50 = 684 nM PMID: 20218621 PPAR_alpha
ZINC49070766 agonist Compound 26 IC50 = 497 nM EC50 = 284 nM PMID: 20218621 PPAR_alpha
ZINC49070899 agonist Compound 17 IC50 = 384 nM EC50 = 520 nM PMID: 20218621 PPAR_alpha
ZINC49072041 agonist Compound 28 IC50 = 4498 nM EC50 = 843 nM PMID: 20218621
ZINC49072043 agonist Compound 29 IC50 = 9444 nM EC50 = 1482 nM PMID: 20218621
ZINC49072045 agonist Compound 30 IC50 = 5293 nM EC50 = 905 nM PMID: 20218621
ZINC49072329 agonist Compound 31 IC50 = 5336 nM EC50 = 826 nM PMID: 20218621
ZINC49072701 agonist Compound 16 IC50 = 1039 nM EC50 = 1100 nM PMID: 20218621 PPAR_alpha
ZINC49088297 agonist Compound 2b EC50 = 4815 nM PMID: 20356736 PPAR_alpha
ZINC49088298 agonist Compound 2c EC50 = 15580 nM PMID: 20356736 PPAR_alpha
ZINC49111118 agonist Compound 2h EC50 = 6386 nM PMID: 20356736 PPAR_alpha
ZINC49111162 agonist Compound 2k EC50 = 4692 nM PMID: 20356736 PPAR_alpha
ZINC49111814 agonist Compound 1a EC50 = 1.14 +/- 0.65 µM PMID: 21450468 PPAR_alpha
ZINC49112294 agonist Compound 2p EC50 = 5036 nM PMID: 20356736
ZINC49112578 agonist Compound 32 IC50 = 10310 nM EC50 = 1257 nM PMID: 20218621
ZINC49126161 agonist Compound 10 IC50 = 41.5 nM EC50 = 247.8 nM PMID: 20218621
ZINC49650047 agonist Compound 8c Ki = 54 nM EC50 = 14 nM PMID: 19376700
ZINC49774679 agonist Compound 7c EC50 = 6.36 µM PMID: 19928766 PPAR_alpha
ZINC49775064 agonist Compound 8a EC50 = 5.87 µM PMID: 19928766 PPAR_alpha
ZINC49775275 agonist Compound 8c EC50 = 2.56 µM PMID: 19928766 PPAR_alpha
ZINC49775445 agonist Compound 7b EC50 = 6.89 µM PMID: 19928766 PPAR_alpha
ZINC49777805 agonist Compound 2u EC50 = 710 nM PMID: 20356736 PPAR_alpha
ZINC49780465 agonist Compound 2t EC50 = 970 nM PMID: 20356736 PPAR_alpha
ZINC49780746 agonist Compound 9 IC50 = 75.4 nM EC50 = 141.4 nM PMID: 20218621 PPAR_alpha
ZINC49780751 agonist Compound 2a EC50 = 2.16 +/- 1.04 µM PMID: 21450468 PPAR_alpha
ZINC49780806 agonist Compound 2c EC50 = 2.81 +/- 0.25 µM PMID: 21450468 PPAR_alpha
ZINC49780852 agonist Compound 22 IC50 = 1194 nM EC50 = 417 nM PMID: 20218621 PPAR_alpha
ZINC49780952 agonist Compound 15 IC50 = 3362 nM EC50 = 2500 nM PMID: 20218621 PPAR_alpha
ZINC49781026 agonist Compound 21 IC50 = 1998 nM EC50 = 398 nM PMID: 20218621 PPAR_alpha
ZINC49781032 agonist Compound 27 IC50 = 2737 nM EC50 = 705 nM PMID: 20218621 PPAR_alpha
ZINC49781081 agonist Compound 2b EC50 = 0.032 +/- 0.01 µM PMID: 21450468 PPAR_alpha
ZINC49781271 agonist Compound 35w EC50 = 1.56 µM PMID: 19928766 PPAR_beta
ZINC49781316 agonist Compound 11 IC50 = 141.2 nM EC50 = 162.0 nM PMID: 20218621 PPAR_alpha
ZINC49781487 agonist Compound 3 PMID: 20036122
ZINC49785590 agonist Compound 7a EC50 = 5.66 µM PMID: 19928766 PPAR_alpha
ZINC49792756 agonist Compound 8b EC50 = 4.61 µM PMID: 19928766 PPAR_alpha
ZINC49793579 agonist Compound 2v EC50 = 1444 nM PMID: 20356736 PPAR_alpha
ZINC49802470 agonist Compound 1d EC50 = 45.23 +/- 3.61 µM PMID: 21450468
ZINC49802655 agonist Compound 14 IC50 = 4057 nM EC50 = 1411 nM PMID: 20218621 PPAR_alpha
ZINC49803057 agonist Compound 20 IC50 = 483 nM EC50 = 20.1 nM PMID: 20218621 PPAR_alpha
ZINC49803976 agonist Compound 35v EC50 = 1.20 µM PMID: 19928766 PPAR_beta
ZINC49804003 agonist Compound 35ad EC50 = 0.60 µM PMID: 19928766 PPAR_beta
ZINC49867778 agonist Compound 32 Ki = 0.15 µM EC50= 0.61 µM PMID: 19464171 PPAR_beta
ZINC49872280 agonist Compound 31 Ki = 0.039 µM EC50= 0.56 µM PMID: 19464171 PPAR_beta
ZINC49877890 agonist Compound 30 Ki = 0.17 µM EC50= 4.5 µM PMID: 19464171 PPAR_beta
ZINC49878168 agonist Compound 3 IC50 = 1 nM EC50 = 1 nM PMID: 19507861
ZINC49878561 agonist MK-0533 IC50 = 9 nM EC50 = 2 nM PMID: 19507861
ZINC49888670 agonist Compound 19 Ki = 1.2 µM EC50= 4.9 µM PMID: 19464171
PPAR_alpha
ZINC49888742 agonist Compound 29 Ki = 0.030 µM EC50= 0.30 µM PMID: 19464171 PPAR_beta
ZINC53226490 agonist Compound 35 EC50 = 0.74 µM PMID: 20527969
ZINC53230898 agonist Compound 39 EC50 = 1.8 µM PMID: 20527969
ZINC53242803 agonist Compound 9 EC50 = 0.18 µM PMID: 20527969
ZINC53298624 agonist Compound 42 EC50 = 0.95 µM PMID: 20527969
ZINC53299018 agonist Compound 45 EC50 = 0.47 µM PMID: 20527969
ZINC53312432 agonist Compound 46 EC50 = 0.25 µM PMID: 20527969
ZINC53312957 agonist Compound 40 EC50 = 0.30 µM PMID: 20527969
ZINC53313118 agonist Compound 33 EC50 = 0.67 µM PMID: 20527969
ZINC53313467 agonist Compound 34 EC50 = 0.25 µM PMID: 20527969
ZINC53314095 agonist Compound 44 EC50 = 2.3 µM PMID: 20527969
ZINC53314115 agonist Compound 36 EC50 = 2.7 µM PMID: 20527969
ZINC53314553 agonist Compound 47 EC50 = 0.42 µM PMID: 20527969
ZINC58563836 agonist Compound 5 EC50 = 0.26 µM PMID: 20656494
ZINC58568368 agonist Compound 3d-6 EC50 = 0.62 µM PMID: 20656494
ZINC58569432 agonist Compound 3d-5 EC50 = 0.58 µM PMID: 20656494
ZINC58574992 agonist Compound 3b-5 EC50 = 0.4 µM PMID: 20656494
ZINC58582900 agonist Compound 3c EC50 = 0.4 µM PMID: 20656494
ZINC58590505 agonist Compound 3b-6 EC50 = 0.47 µM PMID: 20656494
ZINC59672404 agonist Compound 23 EC50 = 4000 nM PMID: 19275963 PPAR_alpha
ZINC60325686 agonist Compound 25 EC50 = 8000 nM PMID: 19275963
PPAR_alpha
ZINC66099417 agonist Compound 12c EC50 = 0.8 +/- 0.02 µM PMID: 21215640
PPAR_alpha
ZINC66099920 agonist Compound (R)-7 EC50 = 3.60 +/- 1.10 nM PMID: 21128600
ZINC66100342 agonist Compound 6a fold induction = 1.47 PMID: 21195611
PPAR_alpha
ZINC66100345 agonist Compound 6b fold induction = 3.05 PMID: 21195611
PPAR_alpha
ZINC66100380 agonist Compound 6c fold induction = 1.44 PMID: 21195611 PPAR_alpha
ZINC66100383 agonist Compound 6d fold induction = 1.75 PMID: 21195611
PPAR_alpha
ZINC66100388 agonist Compound 6f fold induction = 1.20 PMID: 21195611
PPAR_alpha
ZINC66100864 agonist Compound 6g fold induction = 2.83 PMID: 21195611
PPAR_alpha
ZINC66101611 agonist Compound 12a EC50 = 0.006 +/- 0.002 µM PMID: 21215640
PPAR_alpha
ZINC66104666 agonist Compound (S)-7 EC50 = 22.0 +/- 4.00 nM PMID: 21128600
ZINC66166629 agonist Compound 18a EC50 = 0.4 +/- 0.01 µM PMID: 21215640
PPAR_alpha
ZINC66251343 agonist Compound 6h fold induction = 7.39 PMID: 21195611
PPAR_alpha
ZINC66251537 agonist Compound 6i fold induction = 4.36 PMID: 21195611
PPAR_alpha
ZINC66251538 agonist Compound 6j fold induction = 3.87 PMID: 21195611 PPAR_alpha
ZINC66251665 agonist Compound 10m EC50 = 1.9 µM PMID: 21130649 PPAR_alpha
ZINC66259488 agonist Compound 12f EC50 = 1.0 +/- 0.12 µM PMID: 21215640
PPAR_alpha
ZINC66259489 agonist Compound 17a EC50 = 0.3 +/- 0.05 µM PMID: 21215640
PPAR_alpha
ZINC66259818 agonist Compound 10s EC50 = 1.2 µM PMID: 21130649 PPAR_alpha
ZINC66260032 agonist Compound 10b EC50 = 2.0 µM PMID: 21130649 PPAR_alpha
ZINC66262036 agonist Compound 6k fold induction = 1.13 PMID: 21195611
PPAR_alpha
ZINC71282478 agonist Compound 95 EC50 = 220 µM PMID: 21482446
ZINC71296475 agonist Compound 6b EC50 = 4.8 µM PMID: 21377875 PPAR_alpha
ZINC71296990 agonist Compound 9 EC50 = 0.13 µM PMID: 21377875 PPAR_alpha
ZINC71316395 agonist Compound 6a EC50 = 12 µM PMID: 21377875 PPAR_alpha
ZINC71318138 agonist Compound 6d EC50 = 1.7 µM PMID: 21377875 PPAR_alpha
ZINC71318178 agonist Compound 16 EC50 = 3.3 µM PMID: 21377875
ZINC71329589 agonist Compound 6c EC50 = 3.0 µM PMID: 21377875 PPAR_alpha
ZINC71330009 agonist Compound 5d EC50 = 4.6 µM PMID: 21377875
ZINC71330091 agonist Compound 13 EC50 = 6.0 µM PMID: 21377875
ZINC71331069 agonist Compound 5 EC50 = 0.91 µM PMID: 21515063
PPAR_alpha
ZINC71332043 agonist Compound 12 EC50 = 5.9 µM PMID: 21515063
PPAR_alpha
ZINC71334180 agonist Compound 16 EC50 = 2.6 µM PMID: 21515063
PPAR_alpha
ZINC71340511 agonist Compound 13 EC50 = 14.6 µM PMID: 21515063
PPAR_alpha
ZINC71340668 agonist Compound 10 EC50 = 31.1 µM PMID: 21515063
PPAR_alpha
ZINC71340970 agonist Compound 18 EC50 = 5.1 µM PMID: 21515063
PPAR_alpha
ZINC71341094 agonist Compound 15 EC50 = 1.0 µM PMID: 21515063
PPAR_alpha
ZINC72107962 agonist Compound 2n EC50 = 165 nM PMID: 21557540
ZINC72109074 agonist Compound 14 EC50 = 175 nM PMID: 21557540
ZINC72109150 agonist Compound 2k EC50 = 264 nM PMID: 21557540
ZINC72109151 agonist Compound 2l EC50 = 212 nM PMID: 21557540
ZINC72109152 agonist Compound 2m EC50 = 89 nM PMID: 21557540
ZINC72109275 agonist Compound 2i EC50 = 1340 nM PMID: 21557540
ZINC72109276 agonist Compound 2j EC50 = 494 nM PMID: 21557540
ZINC72109283 agonist Compound 2o EC50 = 90 nM PMID: 21557540
ZINC72109927 agonist Compound 2h EC50 = 1820 nM PMID: 21557540
ZINC72113144 agonist Compound 17 EC50 = 7.2 +/- 1.3 µM PMID: 21873070
ZINC72113423 agonist Compound 8 EC50 = 7.8 +/- 2.7 µM PMID: 21873070
ZINC72114209 agonist Compound 15 EC50 = 1.8 µM PMID: 21873070
ZINC72114824 agonist Compound 16 max. activation = 75 +/- 8 % PMID: 21873070
ZINC72179020 agonist Compound 38 pEC50 = 6.3 PMID: 21798739
ZINC72179429 agonist Compound 43 pEC50 = 8.0 PMID: 21798739
ZINC72179646 agonist Compound 41 pEC50 = 7.4 PMID: 21798739
ZINC72179647 agonist Compound 42 pEC50 = 9.3 PMID: 21798739
ZINC72179804 agonist Compound 39 pEC50 = 6.1 PMID: 21798739
ZINC72179805 agonist Compound 40 pEC50 = 7.8 PMID: 21798739
ZINC72179949 agonist Compound 26 pEC50 = 6.8 PMID: 21798739
ZINC72180286 agonist Compound 35 pEC50 = 9.3 PMID: 21798739
ZINC72180394 agonist Compound 32 pEC50 = 8.5 PMID: 21798739
ZINC72180400 agonist Compound 36 pEC50 = 9.1 PMID: 21798739
ZINC72180515 agonist Compound 34 pEC50 = 8.8 PMID: 21798739
ZINC72180565 agonist Compound 29 pEC50 = 8.1 PMID: 21798739
ZINC72180956 agonist Compound 18 pEC50 = 6.7 PMID: 21798739
ZINC72181186 agonist Compound 16 pEC50 = 6.2 PMID: 21798739
ZINC72181187 agonist Compound 17 pEC50 = 8.6 PMID: 21798739
ZINC72181317 agonist Compound 15 pEC50 = 7.3 PMID: 21798739
ZINC72181575 agonist Compound 30 pEC50 = 8.3 PMID: 21798739
ZINC72181576 agonist Compound 31 pEC50 = 6.4 PMID: 21798739
ZINC72182088 agonist Compound 13 pEC50 = 7.4 PMID: 21798739
ZINC72182383 agonist Compound 12 pEC50 = 6.4 PMID: 21798739
ZINC72183168 agonist Compound 24 pEC50 = 7.1 PMID: 21798739
ZINC72183306 agonist Compound 22 pEC50 = 7.1 PMID: 21798739
ZINC72183307 agonist Compound 23 pEC50 = 7.3 PMID: 21798739
ZINC72183315 agonist Compound 25 pEC50 = 7.5 PMID: 21798739
ZINC73221462 agonist Compound 14f EC50 = 0.76 µM PMID: 22197396
ZINC73221468 agonist Compound 14h EC50 = 0.76 µM PMID: 22197396
ZINC73221643 agonist Compound 14l EC50 = 0.11 µM PMID: 22197396
ZINC73223869 agonist Compound 14a EC50 = 0.35 µM PMID: 22197396
ZINC73279110 agonist Compound 14k EC50 = 0.02 µM PMID: 22197396
ZINC73294674 agonist Compound 3 EC50 = 35.2 +/- 2.5 µM PMID: 22341573 PPAR_alpha
ZINC73295120 agonist Compound 7 EC50 = 15.9 +/- 0.5 µM PMID: 22341573 PPAR_alpha
ZINC73295126 agonist Compound 9 EC50 = 2.5 +/- 0.1 µM PMID: 22341573 PPAR_alpha
ZINC73311164 agonist Compound S-10 EC50 = 0.5 +/- 0.2 µM PMID: 22341573 PPAR_alpha