Compound ID | Pharmacological profile | Compound name | Binding data | Activity data | Bibliographic ref | Cross-reactivity | |
CHEMBL1080366 | agonist | Compound 40e | EC50 = 1.87 µM | PMID: 19928766 | |||
CHEMBL1081207 | agonist | Compound 40o | EC50 = 0.46 µM | PMID: 19928766 | |||
CHEMBL1081730 | agonist | Compound 35i | EC50 = 0.018 µM | PMID: 19928766 | |||
CHEMBL116540 | agonist | Compound 68 | EC50 = 0.90 µM | PMID: 12904063 | PPAR_alpha | ||
CHEMBL1169827 | agonist | Compound 1f | EC50 = 0.9 nM | PMID: 21074432 | |||
CHEMBL117402 | agonist | Compound 17 | EC50 = 2.63 µM | PMID: 15177462 |
|
||
CHEMBL118577 | agonist | Compound 19 | EC50 = 3.09 µM | PMID: 15177462 |
|
||
CHEMBL118816 | agonist | Compound 21 | EC50 = 3.62 µM | PMID: 15177462 |
|
||
CHEMBL118939 | agonist | Compound 17 | EC50 = 130 nM | PMID: 16275077 |
|
||
CHEMBL118976 | agonist | Compound 64 | EC50 = 8.0 µM | PMID: 12904063 | PPAR_alpha | ||
CHEMBL119795 | agonist | Compound 11 | EC50 = 2.45 µM | PMID: 15177462 | PPAR_gamma | ||
CHEMBL120009 | agonist | Compound 10 | EC50 = 3.6 µM | PMID: 12904063 |
|
||
CHEMBL120456 | agonist | Compound 9 | EC50 = 2.8 µM | PMID: 12904063 | |||
CHEMBL120611 | agonist | Compound 19 | EC50 = 1.5 µM | PMID: 12904063 | PPAR_alpha | ||
CHEMBL120676 | agonist | Compound 71 | EC50 = 6.60 µM | PMID: 12904063 | PPAR_alpha | ||
CHEMBL120744 | agonist | Compound 16 | EC50 = 3.0 µM | PMID: 12904063 |
|
||
CHEMBL120748 | agonist | Compound 57 | EC50 = 0.40 µM | PMID: 12904063 | |||
CHEMBL122070 | agonist | Compound 74 | EC50 = 3.0 µM | PMID: 12904063 |
|
||
CHEMBL1222408 | agonist | Compound 11d | EC50 = 120 +/- 10 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL1630380 | agonist | Compound 1i | EC50 = 4.5 nM | PMID: 21074432 |
|
||
CHEMBL1630381 | agonist | Compound 1h | EC50 = 6.2 nM | PMID: 21074432 | PPAR_alpha | ||
CHEMBL1630382 | agonist | Compound 1g | EC50 = 11.0 nM | PMID: 21074432 | PPAR_alpha | ||
CHEMBL1630383 | agonist | Compound 2f | EC50 = 1.0 nM | PMID: 21074432 | PPAR_alpha | ||
CHEMBL1630384 | agonist | Compound 2i | EC50 = 1.8 nM | PMID: 21074432 |
|
||
CHEMBL1630385 | agonist | Compound 2h | EC50 = 7.0 nM | PMID: 21074432 | PPAR_gamma | ||
CHEMBL1630386 | agonist | Compound 2g | EC50 = 8.5 nM | PMID: 21074432 | |||
CHEMBL1634195 | agonist | Compound 10 | EC50 = 0.32 µM | PMID: 21094606 | |||
CHEMBL1643192 | agonist | Compound 3 | EC50 = 1.6 µM | PMID: 21094606 | |||
CHEMBL1643193 | agonist | Compound 4 | EC50 = 1.0 µM | PMID: 21094606 | |||
CHEMBL1643194 | agonist | Compound 5 | EC50 = 0.025 µM | PMID: 21094606 | |||
CHEMBL1643196 | agonist | Compound 11 | EC50 = 2.5 µM | PMID: 21094606 | |||
CHEMBL1643202 | agonist | Compound 20 | EC50 = 0.5 µM | PMID: 21094606 | |||
CHEMBL1643203 | agonist | Compound 21 | EC50 = 2.0 µM | PMID: 21094606 | |||
CHEMBL1760269 | agonist | Compound 13 | pIC50 = 7.2 | PEC50 = 6.9 | PMID: 21414782 | ||
CHEMBL1760274 | agonist | Compound 16 | pIC50 = 7.8 | PEC50 = 7.8 | PMID: 21414782 | ||
CHEMBL1760399 | agonist | Compound 17 | pIC50 = 7.1 | PEC50 = 7.2 | PMID: 21414782 | ||
CHEMBL1760400 | agonist | Compound 18 | pIC50 = 6.8 | PEC50 = 6.5 | PMID: 21414782 | ||
CHEMBL1760401 | agonist | Compound 19 | pIC50 = 6.6 | PEC50 = 6.4 | PMID: 21414782 | ||
CHEMBL1760402 | agonist | Compound 20 | pIC50 = 6.3 | PEC50 = 6.3 | PMID: 21414782 | ||
CHEMBL1760403 | agonist | Compound 21 | pIC50 = 6.2 | PEC50 = 6.5 | PMID: 21414782 | ||
CHEMBL1760405 | agonist | Compound 23 | pIC50 = 6.9 | PEC50 = 7.1 | PMID: 21414782 | ||
CHEMBL1760406 | agonist | Compound 24 | pIC50 = 6.1 | PEC50 = 6.4 | PMID: 21414782 | ||
CHEMBL1760407 | agonist | Compound 25 | pIC50 = 6.0 | PEC50 = 6.3 | PMID: 21414782 | ||
CHEMBL1760408 | agonist | Compound 26 | pIC50 = 6.1 | PEC50 = 6.1 | PMID: 21414782 | ||
CHEMBL1760409 | agonist | Compound 27 | pIC50 = 6.3 | PEC50 = 6.3 | PMID: 21414782 | ||
CHEMBL1760410 | agonist | Compound 28 | pIC50 = 5.9 | PEC50 = 5.7 | PMID: 21414782 | ||
CHEMBL1779473 | agonist | Compound 11c | EC50 = 110 +/- 12 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL1779474 | agonist | Compound 11e | EC50 = 4800 +/- 700 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL1779476 | agonist | Compound 11h | EC50 = 4100 +/- 400 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL1779478 | agonist | Compound 11j | EC50 = 1400 +/- 300 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL1779479 | agonist | Compound 11k | EC50 = 1400 +/- 100 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL1813188 | agonist | Compound 11a | EC50 = 13 µM | PMID: 21514830 |
|
||
CHEMBL1813191 | agonist | Compound 12a | EC50 = 29 µM | PMID: 21514830 | PPAR_alpha | ||
CHEMBL1813194 | agonist | Compound 13a | EC50 = 14 µM | PMID: 21514830 |
|
||
CHEMBL1813195 | agonist | Compound 13b | EC50 = 25 µM | PMID: 21514830 |
|
||
CHEMBL1813199 | agonist | Compound 13f | EC50 = 3.2 µM | PMID: 21514830 |
|
||
CHEMBL1813200 | agonist | Compound (S) 13c | EC50 = 7.3 µM | PMID: 21514830 | PPAR_gamma | ||
CHEMBL1813202 | agonist | Compound (S) 13d | EC50 = 1.9 µM | PMID: 21514830 | PPAR_gamma | ||
CHEMBL1813203 | agonist | Compound (R) 13d | EC50 = 9.7 µM | PMID: 21514830 | PPAR_gamma | ||
CHEMBL1813204 | agonist | Compound (S) 13e | EC50 = 1.8 µM | PMID: 21514830 | PPAR_gamma | ||
CHEMBL1927473 | agonist | Compound 2a | EC50 = 55 +/- 4 nM | PMID: 22051054 | PPAR_alpha | ||
CHEMBL1927474 | agonist | Compound 2b | EC50 = 290 +/- 12 nM | PMID: 22051054 | PPAR_alpha | ||
CHEMBL1927475 | agonist | Compound 2c | EC50 = 580 +/- 28 nM | PMID: 22051054 | PPAR_alpha | ||
CHEMBL1934480 | agonist | Compound 14c | EC50 = 7.1 µM | PMID: 22133631 | |||
CHEMBL1934481 | agonist | Compound 14d | EC50 = 2.4 µM | PMID: 22133631 | PPAR_alpha | ||
CHEMBL1934482 | agonist | Compound 14e | EC50 = 1.9 µM | PMID: 22133631 | PPAR_alpha | ||
CHEMBL1934483 | agonist | Compound 14f | EC50 = 8.8 µM | PMID: 22133631 | PPAR_alpha | ||
CHEMBL1934484 | agonist | Compound 14g | EC50 = 3.1 µM | PMID: 22133631 | PPAR_alpha | ||
CHEMBL1934485 | agonist | Compound 14h | EC50 = 43 nM | PMID: 22133631 | PPAR_alpha | ||
CHEMBL200495 | agonist | Compound 5 | IC50 = 0.096 | EC50 = 0.010 µM | PMID: 16451087 |
|
|
CHEMBL2011544 | agonist | Compound 11 | EC50 = 4.9 +/- 0.7 µM | PMID: 22381047 | PPAR_gamma | ||
CHEMBL201581 | agonist | Compound 10c | IC50 = 3.153 µM | EC50 = 4.350 µM | PMID: 16451087 | PPAR_alpha | |
CHEMBL201653 | agonist | Compound 10d | IC50 = 3.256 µM | EC50 = 4.000 µM | PMID: 16451087 | PPAR_alpha | |
CHEMBL201803 | agonist | Compound 10c | EC50 = 500 nM | PMID: 16275077 |
|
||
CHEMBL201832 | agonist | Compound 10b | EC50 = 1000 nM | PMID: 16275077 |
|
||
CHEMBL201880 | agonist | Compound 10k | IC50 = 0.223 µM | EC50 = 0.500 µM | PMID: 16451087 |
|
|
CHEMBL202140 | agonist | Compound 10f | IC50 = 7.616 µM | EC50 = 5.290 µM | PMID: 16451087 | PPAR_gamma | |
CHEMBL202246 | agonist | Compound 10l | IC50 = 2.398 µM | EC50 = 4.900 µM | PMID: 16451087 |
|
|
CHEMBL202617 | agonist | Compound 10h | IC50 = 4.430 µM | EC50 = 5.600 µM | PMID: 16451087 |
|
|
CHEMBL2035057 | agonist | Compound 11t | EC50 = 1.1 nM | PMID: 22534184 | |||
CHEMBL2035058 | agonist | Compound 11f | EC50 = 1.2 nM | PMID: 22534184 | |||
CHEMBL2035059 | agonist | Compound 11g | EC50 = 2.8 nM | PMID: 22534184 | |||
CHEMBL2035060 | agonist | Compound 11h | EC50 = 4.6 nM | PMID: 22534184 | |||
CHEMBL2035061 | agonist | Compound 11i | EC50 = 16.7 nM | PMID: 22534184 | |||
CHEMBL2035062 | agonist | Compound 11j | EC50 = 6.7 nM | PMID: 22534184 | |||
CHEMBL2035063 | agonist | Compound 11k | EC50 = 8.1 nM | PMID: 22534184 | |||
CHEMBL2035064 | agonist | Compound 11l | EC50 = 4.4 nM | PMID: 22534184 | |||
CHEMBL2035065 | agonist | Compound 11m | EC50 = 490.1 nM | PMID: 22534184 | |||
CHEMBL2035067 | agonist | Compound 11o | EC50 = 523.0 nM | PMID: 22534184 | |||
CHEMBL2035068 | agonist | Compound 11p | EC50 = 1.8 nM | PMID: 22534184 | |||
CHEMBL2035069 | agonist | Compound 11q | EC50 = 1.0 nM | PMID: 22534184 | |||
CHEMBL2035070 | agonist | Compound 11r | EC50 = 2.3 nM | PMID: 22534184 | |||
CHEMBL2035071 | agonist | Compound 11s | EC50 = 1.1 nM | PMID: 22534184 | |||
CHEMBL2037577 | agonist | Compound 10a | EC50 = 1.6 nM | PMID: 22534184 | |||
CHEMBL2037578 | agonist | Compound 10b | EC50 = 2.6 nM | PMID: 22534184 | |||
CHEMBL2037579 | agonist | Compound 10c | EC50 = 6.1 nM | PMID: 22534184 | |||
CHEMBL2037580 | agonist | Compound 10d | EC50 = 38.8 nM | PMID: 22534184 | |||
CHEMBL2037581 | agonist | Compound 10e | EC50 = 11.4 nM | PMID: 22534184 | |||
CHEMBL2037582 | agonist | Compound 10f | EC50 = 57.2 nM | PMID: 22534184 | |||
CHEMBL2037583 | agonist | Compound 10g | EC50 = 132 nM | PMID: 22534184 | |||
CHEMBL2037584 | agonist | Compound 11a | EC50 = 60.0 nM | PMID: 22534184 | |||
CHEMBL2037585 | agonist | Compound 11b | EC50 = 9.4 nM | PMID: 22534184 | |||
CHEMBL2037586 | agonist | Compound 11c | EC50 = 4.8 nM | PMID: 22534184 | |||
CHEMBL2037587 | agonist | Compound 11d | EC50 = 1.2 nM | PMID: 22534184 | |||
CHEMBL2037588 | agonist | Compound 11e | EC50 = 2.1 nM | PMID: 22534184 | |||
CHEMBL2064743 | agonist | MDG582 | EC50 = 26.0 +/- 3.6 µM | PMID: 22582973 | PPAR_gamma | ||
CHEMBL212023 | agonist | Compound 12 | IC50 = 9 +/- 0 nM | EC50 = 52 +/- 12 nM | PMID: 16970391 | PPAR_gamma | |
CHEMBL215127 | agonist | Compound 11 | IC50 = 6 +/- 1 nM | EC50 = 25 +/- 5 nM | PMID: 16970391 |
|
|
CHEMBL215582 | agonist | Compound 7 | IC50 = 5 +/- 0 nM | EC50 = 45 +/- 8 nM | PMID: 16970391 |
|
|
CHEMBL229525 | agonist | Compound 10f | EC50 = 5.1 +/- 0.5 nM | PMID: 17532641 |
|
||
CHEMBL229573 | agonist | Compound 10g | EC50 = 1.8 +/- 0.3 nM | PMID: 17532641 |
|
||
CHEMBL229778 | agonist | Compound 5c | EC50 = 6.8 +/- 0.6 nM | PMID: 17532641 |
|
||
CHEMBL229785 | agonist | Compound 10b | EC50 = 120 +/- 10 nM | PMID: 17532641 | PPAR_alpha | ||
CHEMBL229786 | agonist | Compound 10c | EC50 = 700 +/- 150 nM | PMID: 17532641 |
|
||
CHEMBL229831 | agonist | Compound 5e | EC50 = 45 +/- 5 nM | PMID: 17532641 |
|
||
CHEMBL229837 | agonist | Compound 10e | EC50 = 220 +/- 20 nM | PMID: 17532641 |
|
||
CHEMBL229888 | agonist | Compound 10a | EC50 = 210 +/- 30 nM | PMID: 17532641 | PPAR_alpha | ||
CHEMBL230177 | agonist | Compound 16 | EC50 = 6.9 nM | PMID: 17524639 | |||
CHEMBL230179 | agonist | Compound 18 | EC50 = 24.3 nM | PMID: 17524639 | |||
CHEMBL230268 | agonist | Compound 5 | EC50 = 7.0 nM | PMID: 17524639 | |||
CHEMBL230269 | agonist | Compound 6 | EC50 = 3.9 nM | PMID: 17524639 | |||
CHEMBL230372 | agonist | Compound 2 | EC50 = 18.8 nM | PMID: 17524639 | |||
CHEMBL230605 | agonist | Compound 8 | EC50 = 60.0 nM | PMID: 17524639 | |||
CHEMBL231527 | agonist | Compound 11 | EC50 = 23.9 nM | PMID: 17524639 | |||
CHEMBL231528 | agonist | Compound 12 | EC50 = 4.6 nM | PMID: 17524639 | |||
CHEMBL231531 | agonist | Compound 13 | EC50 = 17.0 nM | PMID: 17524639 | |||
CHEMBL231696 | agonist | Compound 6b | EC50 = 0.011 µM | PMID: 17553681 | |||
CHEMBL234485 | agonist | Compound 6d | EC50 = 0.77 µM | PMID: 17553681 | |||
CHEMBL234689 | agonist | Compound 6e | EC50 = 0.24 µM | PMID: 17553681 | |||
CHEMBL234691 | agonist | Compound 6j | EC50 = 0.49 µM | PMID: 17553681 | |||
CHEMBL234692 | agonist | Compound 6k | EC50 = 3.0 µM | PMID: 17553681 | |||
CHEMBL234693 | agonist | Compound 6m | EC50 = 1.2 µM | PMID: 17553681 | |||
CHEMBL234903 | agonist | Compound 6f | EC50 = 0.13 µM | PMID: 17553681 | |||
CHEMBL234904 | agonist | Compound 6g | EC50 = 0.32 µM | PMID: 17553681 | |||
CHEMBL234905 | agonist | Compound 6h | EC50 = 2.0 µM | PMID: 17553681 | |||
CHEMBL234906 | agonist | Compound 6n | EC50 = 3.9 µM | PMID: 17553681 | |||
CHEMBL234907 | agonist | Compound 6o | EC50 = 0.15 µM | PMID: 17553681 | PPAR_alpha | ||
CHEMBL234908 | agonist | Compound 6q | EC50 = 0.29 µM | PMID: 17553681 |
|
||
CHEMBL239351 | agonist | Compound 10 | EC50 = 24 nM | PMID: 17157013 | PPAR_alpha | ||
CHEMBL245464 | agonist | Compound 30 | EC50 = 0.16 µM | PMID: 17553678 |
|
||
CHEMBL245465 | agonist | Compound 31 | EC50 = 5.0 µM | PMID: 17553678 | PPAR_alpha | ||
CHEMBL245664 | agonist | Compound 34 | EC50 = 0.14 µM | PMID: 17553678 | PPAR_alpha | ||
CHEMBL246069 | agonist | Compound 38 | EC50 = 1.4 µM | PMID: 17553678 | PPAR_alpha | ||
CHEMBL246070 | agonist | Compound 40 | EC50 = 0.12 µM | PMID: 17553678 |
|
||
CHEMBL246281 | agonist | Compound 42 | EC50 = 0.83 µM | PMID: 17553678 |
|
||
CHEMBL246282 | agonist | Compound 43 | EC50 = 6.5 µM | PMID: 17553678 | PPAR_gamma | ||
CHEMBL246510 | agonist | Compound 45 | EC50 = 0.003 µM | PMID: 17553678 |
|
||
CHEMBL248324 | agonist | Compound 23 | EC50 = 2.7 µM | PMID: 17553678 |
|
||
CHEMBL248326 | agonist | Compound 25 | EC50 = 2.3 µM | PMID: 17553678 |
|
||
CHEMBL248526 | agonist | Compound 26 | EC50 = 1.4 µM | PMID: 17553678 |
|
||
CHEMBL248527 | agonist | Compound 28 | EC50 = 1.9 µM | PMID: 17553678 |
|
||
CHEMBL255392 | agonist | Compound 11b | EC50 = 360 +/- 40 nM | PMID: 21530275 |
|
||
CHEMBL255426 | agonist | Compound 10l | EC50 = 810 nM | PMID: 18162399 |
|
||
CHEMBL255593 | agonist | Compound 11a | EC50 = 8100 +/- 400 nM | PMID: 21530275 | PPAR_alpha | ||
CHEMBL262558 | agonist | Compound 52 | EC50 = 0.64 µM | PMID: 12904063 | |||
CHEMBL270451 | agonist | Compound 10i | EC50 = 1400 nM | PMID: 18162399 |
|
||
CHEMBL270587 | agonist | Compound 11g | EC50 = 210 +/- 20 nM | PMID: 21530275 |
|
||
CHEMBL270664 | agonist | Compound 10j | EC50 = 250 nM | PMID: 18162399 |
|
||
CHEMBL270801 | agonist | Compound 10e | EC50 = 300 nM | PMID: 18162399 |
|
||
CHEMBL271877 | agonist | Compound 10c | EC50 = 720 nM | PMID: 18162399 |
|
||
CHEMBL305723 | agonist | Compound 2b | EC50 = 4000 nM | PMID: 11527737 |
|
||
CHEMBL307728 | agonist | Compound 1n | EC50 = 320 nM | PMID: 11527737 |
|
||
CHEMBL309778 | agonist | Compound 1m | EC50 = 160 nM | PMID: 11527737 |
|
||
CHEMBL310426 | agonist | Compound 1f | EC50 = 2500 nM | PMID: 11527737 |
|
||
CHEMBL310962 | agonist | Compound 1h | EC50 = 790 nM | PMID: 11527737 |
|
||
CHEMBL311429 | agonist | Compound 1a | EC50 = 10000 nM | PMID: 11527737 |
|
||
CHEMBL312791 | agonist | Compound 1i | EC50 = 500 nM | PMID: 11527737 |
|
||
CHEMBL325723 | agonist | Compound 27 | EC50 = 3.0 µM | PMID: 12904063 |
|
||
CHEMBL33188 | agonist | Compound 16 | EC50 = 1.05 µM | PMID: 15177462 |
|
||
CHEMBL332465 | agonist | Compound 11 | EC50 = 2.4 µM | PMID: 12904063 | PPAR_alpha | ||
CHEMBL376165 | agonist | Compound 5h | EC50 = 1.7 +/- 0.1 nM | PMID: 17532641 |
|
||
CHEMBL387914 | agonist | Compound 5g | EC50 = 21 +/- 1 nM | PMID: 17532641 |
|
||
CHEMBL389769 | agonist | Compound 4 | EC50 = 4.3 nM | PMID: 17524639 | |||
CHEMBL389903 | agonist | Compound 5d | EC50 = 4.8 +/- 0.6 nM | PMID: 17532641 |
|
||
CHEMBL390004 | agonist | Compound 14 | EC50 = 7.4 nM | PMID: 17524639 | |||
CHEMBL390116 | agonist | Compound 10d | EC50 = 40 +/- 6 nM | PMID: 17532641 |
|
||
CHEMBL390199 | agonist | Compound 17 | EC50 = 15.2 nM | PMID: 17524639 | |||
CHEMBL391620 | agonist | Compound 44 | EC50 = 1.3 µM | PMID: 17553678 |
|
||
CHEMBL392810 | agonist | Compound 33 | EC50 = 1.9 µM | PMID: 17553678 |
|
||
CHEMBL393186 | agonist | Compound 6a | EC50 = 0.16 µM | PMID: 17553681 | |||
CHEMBL393987 | agonist | Compound 6i | EC50 = 0.22 µM | PMID: 17553681 | |||
CHEMBL397218 | agonist | Compound 9 | EC50 = 126 nM | PMID: 17524639 | |||
CHEMBL397449 | agonist | Compound 10 | EC50 = 62.1 nM | PMID: 17524639 | |||
CHEMBL397970 | agonist | Compound 1 | EC50 = 79.0 nM | PMID: 17524639 | |||
CHEMBL398117 | agonist | Compound 27 | EC50 = 1.1 µM | PMID: 17553678 |
|
||
CHEMBL398118 | agonist | Compound 29 | EC50 = 8.0 µM | PMID: 17553678 |
|
||
CHEMBL402161 | agonist | Compound 4e | EC50 = 940 +/- 30 nM | PMID: 18662876 |
|
||
CHEMBL425666 | agonist | Compound 5b | EC50 = 15 +/- 4 nM | PMID: 17532641 | PPAR_gamma | ||
CHEMBL425766 | agonist | Compound 10e | IC50 = 0.649 µM | EC50 = 0.610 µM | PMID: 16451087 |
|
|
CHEMBL426371 | agonist | Compound 5f | EC50 = 110 +/- 20 nM | PMID: 17532641 | PPAR_gamma | ||
CHEMBL426483 | agonist | Compound 18 | EC50 = 2000 nM | PMID: 16275077 | PPAR_alpha | ||
CHEMBL427701 | agonist | Compound 41 | EC50 = 0.11 µM | PMID: 17553678 |
|
||
CHEMBL428574 | agonist | Compound 32 | EC50 = 1.1 µM | PMID: 17553678 |
|
||
CHEMBL429824 | agonist | Compound 37 | EC50 = 1.7 µM | PMID: 17553678 |
|
||
CHEMBL433306 | agonist | Compound 1d | EC50 = 1600 nM | PMID: 11527737 |
|
||
CHEMBL433316 | agonist | Compound 2g | EC50 = 2500 nM | PMID: 11527737 |
|
||
CHEMBL437364 | agonist | Compound 6p | EC50 = 0.29 µM | PMID: 17553681 | |||
CHEMBL455957 | agonist | Compound 4c | EC50 = 59 +/- 6 nM | PMID: 18662876 | PPAR_alpha | ||
CHEMBL456752 | agonist | Compound 4f | EC50 = 550 +/- 70 nM | PMID: 18662876 |
|
||
CHEMBL456753 | agonist | Compound 4g | EC50 = 2200 +/- 300 nM | PMID: 18662876 |
|
||
CHEMBL456973 | agonist | Compound 4h | EC50 = 280 +/- 30 nM | PMID: 18662876 |
|
||
CHEMBL456974 | agonist | Compound 4i | EC50 = 94 +/- 9 nM | PMID: 18662876 |
|
||
CHEMBL457405 | agonist | Compound 4k | EC50 = 55 +/- 3 nM | PMID: 18662876 |
|
||
CHEMBL462982 | agonist | Compound 4d | EC50 = 20 +/- 2 nM | PMID: 18662876 |
|
||
CHEMBL501980 | agonist | Compound 16 | Ki = 0.070 µM | EC50 = 7.1 µM | PMID: 19464171 | ||
CHEMBL508953 | agonist | Compound 7f | Transactivation = 1.8 | PMID: 18805005 | PPAR_gamma | ||
CHEMBL514256 | agonist | Compound 4j | EC50 = 60 +/- 7 nM | PMID: 18662876 |
|
||
CHEMBL76676 | agonist | Compound 1l | EC50 = 5000 nM | PMID: 11527737 |
|
||
CHEMBL78442 | agonist | Compound 2e | EC50 = 100 nM | PMID: 11527737 |
|
||
CHEMBL78523 | agonist | Compound 1c | EC50 = 7900 nM | PMID: 11527737 |
|
||
CHEMBL80301 | agonist | Compound 1e | EC50 = 1600 nM | PMID: 11527737 |
|
||
CHEMBL80364 | agonist | Compound 1k | EC50 = 7900 nM | PMID: 11527737 |
|
||
CHEMBL80671 | agonist | Compound 1g | EC50 = 500 nM | PMID: 11527737 |
|
||
CHEMBL80772 | agonist | Compound 1b | EC50 = 7900 nM | PMID: 11527737 |
|
||
CHEMBL80791 | agonist | Compound 2f | EC50 = 500 nM | PMID: 11527737 |
|
||
CHEMBL80905 | agonist | Compound 1j | EC50 = 7900 nM | PMID: 11527737 |
|
||
ZINC00388674 | agonist | Compound 9 | EC50 = 50.6 +/- 5.3 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC00593304 | agonist | Compound 3 | EC50 = 14.9 µM | PMID: 21515063 |
|
||
ZINC00593306 | agonist | Compound 7 | EC50 = 6.7 µM | PMID: 21515063 |
|
||
ZINC00593307 | agonist | Compound 8 | EC50 = 9.8 µM | PMID: 21515063 |
|
||
ZINC00603089 | agonist | Compound 9 | EC50 = 5.4 µM | PMID: 21515063 |
|
||
ZINC01549535 | agonist | Compound 20 | EC50 = 1.0 µM | PMID: 12482434 |
|
||
ZINC01549989 | agonist | gw501516 | IC50 = 1 +/- 0.1 nM | EC50 = 0.85 +/- 0.29 µM | PMID: 12699745 | ||
ZINC01553970 | agonist | Compound 19 | EC50 = 0.5 µM | PMID: 12482434 |
|
||
ZINC01553971 | agonist | Compound 1 | EC50 = 0.54 +/- 0.05 µM | PMID: 17343371 |
|
||
ZINC01554219 | agonist | Compound 9 | Ki = 0.3 nM | EC50 = 20 nM | PMID: 12617924 |
|
|
ZINC01554220 | agonist | Compound 6 | Ki = 93 nM | max at 3 µM = 86% | PMID: 12617924 |
|
|
ZINC01554391 | agonist | L-796449 | IC50 = 6 nM | EC50 = 6 nM | PMID: 12657263 |
|
|
ZINC02541693 | agonist | L-165041 | EC50 = 125 nM | PMID: 16797985 |
|
||
ZINC03817280 | agonist | Compound 10a | IC50 = 3.1 nM | EC50 = 14.7 nM | PMID: 17512197 | ||
ZINC03819472 | agonist | NNC 61-3058 | EC50 = 9.6 µM | PMID: 17379517 |
|
||
ZINC03819473 | agonist | Compound 6 | EC50 = 6.90 +/- 1.08 µM | PMID: 14584939 |
|
||
ZINC03834054 | agonist | L-783483 | IC50 = 10 nnM | EC50 = 5 nM | PMID: 12657263 |
|
|
ZINC03870758 | agonist | gw2433 | EC50 = 0.19 µM | PMID: 10691680 | |||
ZINC03940632 | agonist | Compound 4e | Ki = 2500 nM | EC50 = 3800 nM | PMID: 11720854 |
|
|
ZINC03949277 | agonist | Compound 8 | EC50 = 0.017 +/- 0.001 µM | PMID: 17343371 | |||
ZINC03949282 | agonist | Compound 7 | EC50 = 0.053 +/- 0.003 µM | PMID: 17343371 | |||
ZINC03961820 | agonist | Compound 13 | EC50 = 34 nM | PMID: 17157013 | |||
ZINC03961821 | agonist | Compound 34v | EC50 = 18 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC03961822 | agonist | Compound 34z | EC50 = 218 nM | PMID: 17274610 | |||
ZINC03961823 | agonist | Compound 34ak | EC50 = 3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC03961825 | agonist | Compound 34ad | EC50 = 4.6 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC03961827 | agonist | Compound 34t | EC50 = 5.2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC03976748 | agonist | Compound 10 | EC50 = 0.004 µM | PMID: 17243659 | PPAR_gamma | ||
ZINC04777896 | agonist | Compound 3 | EC50 = 49.5 +/- 4.8 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC06001877 | agonist | Compound 6 | EC50 = 33.9 +/- 3.6 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC08022594 | agonist | gw0742 | IC50 = 1 +/- 0.01 nM | EC50 = 1 +/- 0.2 nM | PMID: 12699745 | PPAR_gamma | |
ZINC08455242 | agonist | MDG559 | EC50 = 21.0 +/- 6.7 µM | PMID: 22582973 | PPAR_gamma | ||
ZINC09933928 | antagonist | Compound 9 | IC50 = 7.2 µM | PMID: 18821746 | |||
ZINC1024901 | antagonist | gsk3787 | pIC50 = 6.7 | pIC50 = 6.9 | PMID: 20128594 | ||
ZINC12358141 | agonist | Compound 4 | EC50 = 0.79 µM | PMID: 10508427 |
|
||
ZINC12358209 | agonist | Compound 7 | EC50 = 5.7 µM | PMID: 12482434 |
|
||
ZINC12358210 | agonist | Compound 8 | EC50 = 8.3 µM | PMID: 12482434 |
|
||
ZINC12358211 | agonist | Compound 9 | EC50 = 3.4 µM | PMID: 12482434 |
|
||
ZINC12358212 | agonist | Compound 10 | EC50 = 2.2 µM | PMID: 12482434 |
|
||
ZINC12358213 | agonist | Compound 11 | EC50 = 2.2 µM | PMID: 12482434 |
|
||
ZINC12358214 | agonist | Compound 12 | EC50 = 0.9 µM | PMID: 12482434 |
|
||
ZINC12358215 | agonist | Compound 13 | EC50 = 3.4 µM | PMID: 12482434 |
|
||
ZINC12358216 | agonist | Compound 14 | EC50 = 0.6 µM | PMID: 12482434 |
|
||
ZINC12358217 | agonist | Compound 15 | EC50 = 2.0 µM | PMID: 12482434 |
|
||
ZINC12358218 | agonist | Compound 16 | EC50 = 2.0 µM | PMID: 12482434 |
|
||
ZINC12358219 | agonist | Compound 17 | EC50 = 0.7 µM | PMID: 12482434 |
|
||
ZINC12358236 | agonist | Compound 2 | Ki = 3.7 nM | max at 3 µM = 34 % | PMID: 12617924 |
|
|
ZINC12358237 | agonist | Compound 4 | Ki = 508.0 nM | EC50 = 147 nM | PMID: 12617924 |
|
|
ZINC12358238 | agonist | Compound 5 | Ki = 5 nM | EC50 = 3 nM | PMID: 12617924 |
|
|
ZINC12358239 | agonist | Compound 7 | Ki = 203 nM | max at 3 µM = 59% | PMID: 12617924 |
|
|
ZINC12358240 | agonist | Compound 10 | Ki = 165 nM | EC50 = 400 nM | PMID: 12617924 |
|
|
ZINC12358241 | agonist | Compound 14 | Ki = 2 nM | Max % at 3µM = 74 % | PMID: 12617924 |
|
|
ZINC12358242 | agonist | Compound 15 | Ki = 37.5 nM | Max % at 3µM = 74 % | PMID: 12617924 |
|
|
ZINC12358243 | agonist | Compound 16 | Ki = 529 nM | Max % at 3µM = 18% | PMID: 12617924 |
|
|
ZINC12358244 | agonist | Compound 17 | Ki = 317 nM | EC50 = 860 nM | PMID: 12617924 |
|
|
ZINC12358245 | agonist | Compound 27 | Ki = 18 nM | EC50 = 148 nM | PMID: 12617924 |
|
|
ZINC12358246 | agonist | Compound 28 | Ki = 265 nM | EC50 = 640 nM | PMID: 12617924 |
|
|
ZINC12358247 | agonist | Compound 18 | Ki = 3.7 nM | EC50 = 16 nM | PMID: 12617924 |
|
|
ZINC12358248 | agonist | Compound 19 | Ki = 4.6 nM | EC50 = 13 nM | PMID: 12617924 |
|
|
ZINC12358250 | agonist | Compound 20 | Ki = 136 nM | Max % at 3µM = 117% | PMID: 12617924 |
|
|
ZINC12358252 | agonist | Compound 21 | Ki = 23 nM | EC50 = 172 nM | PMID: 12617924 |
|
|
ZINC12358253 | agonist | Compound 24 | Ki = 47 nM | Max % at 3µM = 127% | PMID: 12617924 |
|
|
ZINC12358254 | agonist | Compound 25 | Ki = 110 nM | Max % at 3µM = 85% | PMID: 12617924 |
|
|
ZINC12358255 | agonist | Compound 29 | Ki = 156 nM | Max % at 3µM = 69% | PMID: 12617924 |
|
|
ZINC12358256 | agonist | Compound 30 | Ki = 38 nM | EC50 = 183 nM | PMID: 12617924 |
|
|
ZINC12358257 | agonist | Compound 1 | IC50 = 20 nM | EC50 = 80 nM | PMID: 12657263 |
|
|
ZINC12358258 | agonist | Compound 2 | IC50 = 20 nM | EC50 = 10 nM | PMID: 12657263 |
|
|
ZINC12358259 | agonist | Compound 3 | IC50 = 10 nM | EC50 = 9 nM | PMID: 12657263 |
|
|
ZINC12358260 | agonist | L-165461 | IC50 = 4 nM | EC50 = 11 nM | PMID: 12657263 |
|
|
ZINC12358261 | agonist | Compound 6 | IC50 = 40 nM | EC50 = 12 nM | PMID: 12657263 |
|
|
ZINC12358348 | agonist | Compound 15 | IC50 =1200 +/- 120 nM | EC50 = 3000 +/- 19 nM | PMID: 14613314 |
|
|
ZINC12358350 | agonist | Compound 17 | IC50 = 880 +/- 31 nM | EC50 = 3000 +/- 20 nM | PMID: 14613314 |
|
|
ZINC12358351 | agonist | Compound 18 | IC50 = 1700 +/- 15 nM | EC50 = 3000 +/- 20 nM | PMID: 14613314 |
|
|
ZINC12358352 | agonist | Compound 19 | IC50 = 740 +/- 70 nM | EC50 = 2900 +/- 8 nM | PMID: 14613314 |
|
|
ZINC12504466 | agonist | Compound 2 | EC50 = 0.500 µM | PMID: 17034149 |
|
||
ZINC13260173 | agonist | Compound 4 | pIC50 = 8.1 | PEC50 = 6.9 | PMID: 18722772 | ||
ZINC13489471 | agonist | Compound 7a | IC50 = 1.0 +/- 0.07 µM | EC50 = 1.9 +/- 0.39 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489472 | agonist | Compound 7b | IC50 = 0.03 +/- 0.002 µM | EC50 = 0.09 +/- 0.02 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489473 | agonist | Compound 7c | IC50 = 1.0 +/- 0.03 µM | EC50 = 0.02 +/- 0.006 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489474 | agonist | Compound 7d | IC50 = 0.06 µM | EC50 = 0.03 +/- 0.03 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489475 | agonist | Compound 7e | IC50 = 0.09 +/- 0.003 µM | EC50 = 0.06 +/- 0.02 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489476 | agonist | Compound 7f | IC50 = 5.5 +/- 0.28 µM | EC50 = 5.9 +/- 5.5 µM | PMID: 12699745 | ||
ZINC13489477 | agonist | Compound 7g | IC50 = 0.34 +/- 0.008 µM | EC50 = 0.47 +/- 0.18 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489478 | agonist | Compound 7h | IC50 = 0.03 +/- 0.001 µM | EC50 = 0.03 +/- 0.002 µM | PMID: 12699745 | ||
ZINC13489479 | agonist | Compound 7i | IC50 = 0.09 +/- 0.002 µM | EC50 = 0.42 +/- 0.18 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13489480 | agonist | Compound 7j | IC50 = 0.001 +/- 0.0001 µM | EC50 = 0.01 +/- 0.001 µM | PMID: 12699745 | PPAR_gamma | |
ZINC13980247 | agonist | Compound 10 | IC50 = 183 +/- 0 nM | EC50 = 339 +/- 0 nM | PMID: 16970391 | PPAR_gamma | |
ZINC13981352 | agonist | Compound 32 | EC50 = 8.6 nM | PMID: 19168353 | |||
ZINC13981353 | agonist | Compound 5 | EC50 = 17.1 nM | PMID: 19168353 | |||
ZINC13981355 | agonist | Compound 13 | EC50 = 26.8 nM | PMID: 19168353 | |||
ZINC13981356 | agonist | Compound 10 | EC50 = 28.4 nM | PMID: 19168353 | |||
ZINC13981358 | agonist | Compound 30 | EC50 = 22.4 nM | PMID: 19168353 | |||
ZINC13981360 | agonist | Compound 31 | EC50 = 23.3 nM | PMID: 19168353 | |||
ZINC13982030 | agonist | Compound 13 | EC50 (%inhibition) = 42.6 | PMID: 18083521 |
|
||
ZINC13983071 | agonist | Compound 11 | EC50 = 2.060 µM | PMID: 18947994 |
|
||
ZINC13983075 | agonist | Compound 9 | EC50 = 4.850 µM | PMID: 18947994 |
|
||
ZINC13983079 | agonist | Compound 27 | EC50 = 1.63 µM | PMID: 18947994 |
|
||
ZINC13983521 | agonist | Compound 13a | Transactivation = 1.0 | PMID: 18805005 | PPAR_gamma | ||
ZINC13983527 | agonist | Compound 9 | Transactivation = 1.0 | PMID: 18805005 | PPAR_gamma | ||
ZINC13985145 | agonist | Compound 2 | EC50 = 0.003 µM | PMID: 21094606 | |||
ZINC14096589 | agonist | Compound 5 | EC50 = 3.1 µM | PMID: 10508427 |
|
||
ZINC14115100 | agonist | gw9578 | EC50 = 1.4 µM | PMID: 10691680 |
|
||
ZINC14209392 | agonist | Compound 9 | IC50 = 3 +/- 1 nM | EC50 = 5 +/- 1 nM | PMID: 16970391 |
|
|
ZINC14209394 | agonist | Compound 14 | IC50 = 4 +/- 0 nM | EC50 = 5 +/- 0 nM | PMID: 16970391 |
|
|
ZINC14588894 | agonist | Compound 7 | EC50 = 48.5 +/- 4.2 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC14976992 | agonist | Compound 17a | EC50 = 44 nM | PMID: 17274610 | |||
ZINC14976995 | agonist | Compound 17b | EC50 = 8.9 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14976998 | agonist | Compound 17c | EC50 = 4.2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977001 | agonist | Compound 17d | EC50 = 13 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977004 | agonist | Compound 17e | EC50 = 6.7 nM | PMID: 17274610 | |||
ZINC14977007 | agonist | Compound 17f | EC50 = 6.6 nM | PMID: 17274610 | |||
ZINC14977010 | agonist | Compound 17g | EC50 = 7.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977013 | agonist | Compound 17h | EC50 = 43 nM | PMID: 17274610 | |||
ZINC14977016 | agonist | Compound 17i | EC50 = 56 nM | PMID: 17274610 | |||
ZINC14977019 | agonist | Compound 17j | EC50 = 67 nM | PMID: 17274610 | |||
ZINC14977022 | agonist | Compound 29f | EC50 = 11 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977025 | agonist | Compound 17k | EC50 = 117 nM | PMID: 17274610 | |||
ZINC14977028 | agonist | Compound 17l | EC50 = 4.6 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977031 | agonist | Compound 17m | EC50 = 2.4 nM | PMID: 17274610 | |||
ZINC14977034 | agonist | Compound 17n | EC50 = 1.6 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977037 | agonist | Compound 17o | EC50 = 25 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977040 | agonist | Compound 17p | EC50 = 1.9 nM | PMID: 17274610 | |||
ZINC14977044 | agonist | Compound 17q | EC50 = 7.5 nM | PMID: 17274610 | |||
ZINC14977051 | agonist | Compound 17r | EC50 = 2.7 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977054 | agonist | Compound 17s | EC50 = 14 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977058 | agonist | Compound 17t | EC50 = 2.2 nM | PMID: 17274610 | |||
ZINC14977061 | agonist | Compound 17u | EC50 = 11 nM | PMID: 17274610 | |||
ZINC14977064 | agonist | Compound 17v | EC50 = 367 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977067 | agonist | Compound 17w | EC50 = 2230 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977072 | agonist | Compound 17x | EC50 = 3.4 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977075 | agonist | Compound 29a | EC50 = 5.9 nM | PMID: 17274610 | |||
ZINC14977078 | agonist | Compound 29b | EC50 = 3.8 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977081 | agonist | Compound 29c | EC50 = 1.5 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977084 | agonist | Compound 29d | EC50 = 2.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977087 | agonist | Compound 29e | EC50 = 43 nM | PMID: 17274610 | |||
ZINC14977091 | agonist | Compound 29g | EC50 = 5.6 nM | PMID: 17274610 | |||
ZINC14977098 | agonist | Compound 29h | EC50 = 2.2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977102 | agonist | Compound 29i | EC50 = 0.95 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977105 | agonist | Compound 34a | EC50 = 1.6 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977108 | agonist | Compound 34b | EC50 = 0.58 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977111 | agonist | Compound 34c | EC50 = 2.7 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977114 | agonist | Compound 34d | EC50 = 4.4 nM | PMID: 17274610 | |||
ZINC14977118 | agonist | Compound 34e | EC50 = 11 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977121 | agonist | Compound 34f | EC50 = 2.5 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977124 | agonist | Compound 34g | EC50 = 11 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977127 | agonist | Compound 34h | EC50 = 3.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977130 | agonist | Compound 34i | EC50 = 2.9 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977135 | agonist | Compound 34j | EC50 = 2.9 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977140 | agonist | Compound 34k | EC50 = 4 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977143 | agonist | Compound 34l | EC50 = 1.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977146 | agonist | Compound 34m | EC50 = 3.5 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977150 | agonist | Compound 34n | EC50 = 4.1 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977153 | agonist | Compound 34o | EC50 = 2.2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977156 | agonist | Compound 34p | EC50 = 1.9 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977159 | agonist | Compound 34q | EC50 = 3.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977162 | agonist | Compound 34r | EC50 = 4.0 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977165 | agonist | Compound 34s | EC50 = 1.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977169 | agonist | Compound 34u | EC50 = 6.9 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977174 | agonist | Compound 34w | EC50 = 3.4 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977178 | agonist | Compound 34x | EC50 = 4.4 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977181 | agonist | Compound 34y | EC50 = 2.1 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977184 | agonist | Compound 34aa | EC50 = 46 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977187 | agonist | Compound 34ab | EC50 = 28 nM | PMID: 17274610 | |||
ZINC14977190 | agonist | Compound 34ac | EC50 = 12 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977193 | agonist | Compound 34ae | EC50 = 1.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977197 | agonist | Compound 34af | EC50 = 3.0 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977200 | agonist | Compound 34ag | EC50 = 1.2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977203 | agonist | Compound 34ah | EC50 = 2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977206 | agonist | Compound 34ai | EC50 = 3.4 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977209 | agonist | Compound 34aj | EC50 = 2.3 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977213 | agonist | Compound 34al | EC50 = 3.2 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977216 | agonist | Compound 34am | EC50 = 6 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC14977219 | agonist | Compound 34an | EC50 = 5.4 nM | PMID: 17274610 | PPAR_alpha | ||
ZINC15112963 | agonist | Compound 10 | EC50 = 22.6 +/- 1.8 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC16052148 | agonist | Compound 10 | EC50 = 4.300 µM | PMID: 17034149 |
|
||
ZINC16052349 | agonist | Compound 25a | EC50 = 2.83 +/- 1.18 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC26743888 | agonist | Compound 19 | EC50 = 93 nM | PMID: 11677135 |
|
||
ZINC26744992 | agonist | Compound 20 | EC50 = 430 nM | PMID: 11677135 |
|
||
ZINC26747370 | agonist | Compound 21 | EC50 = 1000 nM | PMID: 11677135 |
|
||
ZINC26747391 | agonist | Compound 18 | EC50 = 160 nM | PMID: 11677135 |
|
||
ZINC26749852 | agonist | Compound 22 | EC50 = 1000 nM | PMID: 11677135 |
|
||
ZINC27101121 | agonist | Compound 12 | EC50 = 4.68 µM | PMID: 15177462 | PPAR_gamma | ||
ZINC27101582 | agonist | Compound 14 | EC50 = 1.27 µM | PMID: 15177462 |
|
||
ZINC27102276 | agonist | Compound 18 | EC50 = 3.16 µM | PMID: 15177462 |
|
||
ZINC27103304 | agonist | Compound 10 | EC50 = 3.31 µM | PMID: 15177462 |
|
||
ZINC28123579 | agonist | Compound 8a | EC50 = 2.17 +/- 1.60 µM | PMID: 14584939 |
|
||
ZINC28123586 | agonist | Compound 3 | EC50 = 15 µM | PMID: 15713415 | PPAR_alpha | ||
ZINC28125812 | agonist | Compound 7 | EC50 = 2.08 +/- 1.38 µM | PMID: 14584939 |
|
||
ZINC28127637 | agonist | Compound 1 | EC50 = 18 µM | PMID: 17379517 |
|
||
ZINC28130594 | agonist | Compound 9 | EC50 = 19 µM | PMID: 15713415 | PPAR_alpha | ||
ZINC28131151 | agonist | Compound 6 | EC50 = 1.8 µM | PMID: 15713415 | PPAR_alpha | ||
ZINC28131157 | agonist | Compound 7 | EC50 = 4.1 µM | PMID: 15713415 | PPAR_alpha | ||
ZINC28232511 | agonist | Compound 6f | EC50 = 2.0 µM | PMID: 11354382 | PPAR_alpha | ||
ZINC28235468 | agonist | Compound 6a | EC50 = 1.1 µM | PMID: 11354382 | PPAR_alpha | ||
ZINC28235832 | agonist | Compound 6c | EC50 = 5.0 µM | PMID: 11354382 | PPAR_alpha | ||
ZINC28236053 | agonist | Compound 6h | EC50 = 4.0 µM | PMID: 11354382 | PPAR_alpha | ||
ZINC28569243 | agonist | Compound 16a | EC50 = 12 nM | PMID: 16275077 |
|
||
ZINC28569401 | agonist | Compound 16b | EC50 = 23 nM | PMID: 16275077 |
|
||
ZINC28569402 | agonist | Compound 19 | EC50 = 700 nM | PMID: 16275077 | PPAR_alpha | ||
ZINC28604428 | agonist | Compound 23 | EC50 = 4.05 +/- 1.1 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC28635465 | agonist | Compound 1 | EC50 = 47.6 +/- 4.6 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC28652276 | agonist | Compound 5h | EC50 = 1.7 +/- 0.1 nM | PMID: 17532641 | |||
ZINC28652283 | agonist | Compound (R)-5i | EC50 = 3000 +/- 300 nM | PMID: 17532641 | PPAR_alpha | ||
ZINC28652287 | agonist | Compound (S)-5i | EC50 =1.9 +/- 0.2 nM | PMID: 17532641 | PPAR_alpha | ||
ZINC28704625 | agonist | Compound 3S | EC50 = 25.0 nM | PMID: 17524639 | |||
ZINC28704627 | agonist | Compound 3R | EC50 = 1.9 nM | PMID: 17524639 | |||
ZINC28704665 | agonist | Compound 7S | EC50 = 70.0 nM | PMID: 17524639 | |||
ZINC28704667 | agonist | Compound 7R | EC50 = 2.1 nM | PMID: 17524639 | |||
ZINC28704699 | agonist | Compound 15R | EC50 = 0.03 nM | PMID: 17524639 | |||
ZINC28710190 | agonist | Compound 21 | EC50 = 10 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28710191 | agonist | Compound 22 | EC50 = 6 nM | PMID: 18155554 |
|
||
ZINC28710192 | agonist | Compound 23 | EC50 = 3 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28710193 | agonist | Compound 24 | EC50 = 18 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28710194 | agonist | Compound 36 | EC50 = 93 +/- 7 nM | PMID: 17608467 | |||
ZINC28710197 | agonist | Compound 76 | EC50 = 3 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28710198 | agonist | Compound 77 | EC50 = 12 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28821850 | agonist | Compound 56 | EC50 = 26 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28821851 | agonist | Compound 57 | EC50 = 58 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC28822316 | agonist | Compound 14 | IC50 = 1.7 nM | EC50 = 13 nM | PMID: 17498950 | ||
ZINC28822317 | agonist | Compound 15 | IC50 = 19 nM | EC50 = 252 nM | PMID: 17498950 | ||
ZINC28822318 | agonist | Compound 16 | IC50 = 20 nM | EC50 = 374 nM | PMID: 17498950 | ||
ZINC28822319 | agonist | Compound 17 | IC50 = 136 nM | EC50 = 295 nM | PMID: 17498950 | ||
ZINC28822322 | agonist | Compound 13a | IC50 = 10 nM | EC50 = 251 nM | PMID: 17498950 | ||
ZINC28822330 | agonist | Compound 28e | IC50 = 1.7 nM | EC50 = 70 nM | PMID: 17498950 | ||
ZINC28822331 | agonist | Compound 28b | IC50 = 10.4 nM | EC50 = 230 nM | PMID: 17498950 | ||
ZINC28822334 | agonist | Compound 28a | IC50 = 286 nM | EC50 = 2610 nM | PMID: 17498950 | ||
ZINC28822682 | agonist | Compound 10b | IC50 = 7.7 nM | EC50 = 226 nM | PMID: 17512197 | ||
ZINC28822697 | agonist | Compound 10c | IC50 = 11 nM | EC50 = 305 nM | PMID: 17512197 | ||
ZINC28822699 | agonist | Compound 10d | IC50 = 14 nM | EC50 = 243 nM | PMID: 17512197 | ||
ZINC28822700 | agonist | Compound 10e | IC50 = 81 nM | EC50 = 323 nM | PMID: 17512197 | ||
ZINC28822702 | agonist | Compound 10f | IC50 = 25 nM | EC50 = 1610 nM | PMID: 17512197 | ||
ZINC28822705 | agonist | Compound 10h | IC50 = 58 nM | EC50 = 227 nM | PMID: 17512197 | ||
ZINC28822706 | agonist | Compound 10i | IC50 = 23 nM | EC50 = 638 nM | PMID: 17512197 | ||
ZINC28822707 | agonist | Compound 10j | IC50 = 37 nM | EC50 = 656 nM | PMID: 17512197 | ||
ZINC28822708 | agonist | Compound 10k | IC50 = 375 nM | EC50 = 6360 nM | PMID: 17512197 | ||
ZINC28822709 | agonist | Compound 10l | IC50 = 37 nM | EC50 = 561 nM | PMID: 17512197 | ||
ZINC28822710 | agonist | Compound 10m | IC50 = 97 nM | EC50 = 2630 nM | PMID: 17512197 | ||
ZINC28822711 | agonist | Compound 10n | IC50 = 244 nM | EC50 = 2230 nM | PMID: 17512197 | ||
ZINC28822712 | agonist | Compound 10o | IC50 = 43 nM | EC50 = 172 nM | PMID: 17512197 | ||
ZINC28822713 | agonist | Compound 10p | IC50 = 15 nM | EC50 = 166 nM | PMID: 17512197 | ||
ZINC28822714 | agonist | Compound 10q | IC50 = 3.6 nM | EC50 = 1070 nM | PMID: 17512197 | ||
ZINC28822715 | agonist | Compound 10r | IC50 = 662 nM | EC50 = 3120 nM | PMID: 17512197 | ||
ZINC28822716 | agonist | Compound 10s | IC50 = 24.1 nM | EC50 = 1490 nM | PMID: 17512197 | ||
ZINC28822717 | agonist | Compound 10t | IC50 = 81 nM | EC50 = 3440 nM | PMID: 17512197 | ||
ZINC28825459 | agonist | Compound 5 | IC50 = 6 nM | EC50 = 95 nM | PMID: 18029178 |
|
|
ZINC28825460 | agonist | Compound 6 | IC50 = 3 nM | EC50 = 38 nM | PMID: 18029178 |
|
|
ZINC28825461 | agonist | Compound 7 | IC50 = 4 nM | EC50 = 81 nM | PMID: 18029178 |
|
|
ZINC28825462 | agonist | Compound 8 | IC50 = 3 nM | EC50 = 59 nM | PMID: 18029178 |
|
|
ZINC28825463 | agonist | Compound 9 | IC50 = 4 nM | EC50 = 22 nM | PMID: 18029178 |
|
|
ZINC28825464 | agonist | Compound 10 | IC50 = 3 nM | EC50 = 36 nM | PMID: 18029178 |
|
|
ZINC28825465 | agonist | Compound 11 | IC50 = 40 nM | EC50 = 2870 nM | PMID: 18029178 | PPAR_gamma | |
ZINC28825466 | agonist | Compound 12 | IC50 = 32 nM | EC50 = 409 nM | PMID: 18029178 |
|
|
ZINC28825467 | agonist | Compound 13 | IC50 = 4 nM | EC50 = 30 nM | PMID: 18029178 |
|
|
ZINC28825468 | agonist | Compound 14 | IC50 = 4 nM | EC50 = 286 nM | PMID: 18029178 |
|
|
ZINC28825469 | agonist | Compound 15 | IC50 = 6 nM | EC50 = 254 nM | PMID: 18029178 |
|
|
ZINC28825470 | agonist | Compound 16 | IC50 = 54 nM | EC50 = 50 nM | PMID: 18029178 |
|
|
ZINC28825471 | agonist | Compound 17 | IC50 = 12 nM | EC50 = 376 nM | PMID: 18029178 |
|
|
ZINC28825472 | agonist | Compound 18 | IC50 = 64 nM | EC50 = 1878 nM | PMID: 18029178 | PPAR_gamma | |
ZINC28825473 | agonist | Compound 19 | IC50 = 3 nM | EC50 = 96 nM | PMID: 18029178 |
|
|
ZINC28825474 | agonist | Compound 20 | IC50 = 5 nM | EC50 = 4 nM | PMID: 18029178 |
|
|
ZINC28825475 | agonist | Compound 21 | IC50 = 6 nM | EC50 = 86 nM | PMID: 18029178 |
|
|
ZINC28825476 | agonist | Compound 22 | IC50 = 3 nM | EC50 = 48 nM | PMID: 18029178 |
|
|
ZINC28825477 | agonist | Compound 23 | IC50 = 3 nM | EC50 = 119 nM | PMID: 18029178 |
|
|
ZINC28825478 | agonist | Compound 24 | IC50 = 5 nM | EC50 = 33 nM | PMID: 18029178 | PPAR_gamma | |
ZINC28890851 | agonist | Compound 7 | IC50 = 5 nM | EC50 = 6 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890866 | agonist | Compound 8 | IC50 = 8 nM | EC50 = 42 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890871 | agonist | Compound 9 | IC50 = 9 nM | EC50 = 41 nM | PMID: 17129725 |
|
|
ZINC28890877 | agonist | Compound 10 | IC50 = 14 nM | EC50 = 399 nM | PMID: 17129725 |
|
|
ZINC28890881 | agonist | Compound 11 | IC50 = 3 nM | EC50 = 9 nM | PMID: 17129725 |
|
|
ZINC28890886 | agonist | Compound 12 | IC50 = 5 nM | EC50 = 15 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890891 | agonist | Compound 13 | IC50 = 5 nM | EC50 = 5 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890901 | agonist | Compound 14 | IC50 = 3 nM | EC50 = 22 nM | PMID: 17129725 |
|
|
ZINC28890922 | agonist | Compound 15 | IC50 = 12 nM | EC50 = 25 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890927 | agonist | Compound 16 | IC50 = 13 nM | EC50 = 274 nM | PMID: 17129725 |
|
|
ZINC28890931 | agonist | Compound 17 | IC50 = 5 nM | EC50 = 50 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890938 | agonist | Compound 18 | IC50 = 2 nM | EC50 = 24 nM | PMID: 17129725 | PPAR_gamma | |
ZINC28890943 | agonist | Compound 19 | IC50 = 4 nM | EC50 = 6 nM | PMID: 17129725 |
|
|
ZINC28890948 | agonist | Compound 20 | IC50 = 3 nM | EC50 = 7 nM | PMID: 17129725 |
|
|
ZINC28890954 | agonist | Compound 21 | IC50 = 3 nM | EC50 = 6 nM | PMID: 17129725 |
|
|
ZINC28891480 | agonist | Compound 11 | EC50 = 9 nM | PMID: 17157013 | |||
ZINC28891487 | agonist | Compound 12 | EC50 = 10 nM | PMID: 17157013 | |||
ZINC28891492 | agonist | Compound 14 | EC50 = 28 nM | PMID: 17157013 | |||
ZINC28891497 | agonist | Compound 15 | EC50 = 58 nM | PMID: 17157013 | |||
ZINC28891503 | agonist | Compound 16 | EC50 = 12 nM | PMID: 17157013 | |||
ZINC28891508 | agonist | Compound 17 | EC50 = 83 nM | PMID: 17157013 | |||
ZINC28891516 | agonist | Compound 18 | EC50 = 7 nM | PMID: 17157013 | |||
ZINC28891521 | agonist | Compound 19 | EC50 = 7 nM | PMID: 17157013 | |||
ZINC28891546 | agonist | Compound 20 | EC50 = 41 nM | PMID: 17157013 | |||
ZINC28891551 | agonist | Compound 21 | EC50 = 7 nM | PMID: 17157013 | |||
ZINC28891564 | agonist | Compound 22 | EC50 = 23 nM | PMID: 17157013 | |||
ZINC28891589 | agonist | Compound 23 | EC50 = 25 nM | PMID: 17157013 | |||
ZINC28891599 | agonist | Compound 24 | EC50 = 16 nM | PMID: 17157013 | |||
ZINC28891605 | agonist | Compound 25 | EC50 = 2 nM | PMID: 17157013 | |||
ZINC28891622 | agonist | Compound 26 | EC50 = 11 nM | PMID: 17157013 | |||
ZINC28900607 | agonist | Compound 20 | EC50 = 0.8 µM | PMID: 17553678 |
|
||
ZINC28900610 | agonist | Compound 21 | EC50 = 1.4 µM | PMID: 17553678 |
|
||
ZINC28900634 | agonist | Compound 24 R | EC50 = 0.002 µM | PMID: 17553678 |
|
||
ZINC28900640 | agonist | Compound 24 S | EC50 = 0.13 µM | PMID: 17553678 |
|
||
ZINC28900750 | agonist | Compound 35 R | EC50 = 1.19 µM | PMID: 17553678 |
|
||
ZINC28900755 | agonist | Compound 35 S | EC50 = 1.57 µM | PMID: 17553678 |
|
||
ZINC28900759 | agonist | Compound 36 R | EC50 = 1.58 µM | PMID: 17553678 |
|
||
ZINC28900764 | agonist | Compound 36 S | EC50 = 1.80 µM | PMID: 17553678 |
|
||
ZINC28902530 | agonist | Compound 6 | EC50 = 2.81 µM | PMID: 17524643 | |||
ZINC28902543 | agonist | Compound 9 | EC50 = 4.88 µM | PMID: 17524643 | PPAR_gamma | ||
ZINC28902548 | agonist | Compound 10 | EC50 = 0.94 µM | PMID: 17524643 | PPAR_gamma | ||
ZINC28902553 | agonist | Compound 11 | EC50 = 1.74 µM | PMID: 17524643 | |||
ZINC28902558 | agonist | Compound 12 | EC50 = 1.36 µM | PMID: 17524643 | |||
ZINC28902563 | agonist | Compound 13 | EC50 = 2.61 µM | PMID: 17524643 | |||
ZINC28902567 | agonist | Compound 14 | EC50 = 2.55 µM | PMID: 17524643 | |||
ZINC28902571 | agonist | Compound 15 | EC50 = 1.17 µM | PMID: 17524643 | |||
ZINC28902576 | agonist | Compound 16 | EC50 = 2.97 µM | PMID: 17524643 | |||
ZINC28902581 | agonist | Compound 17 | EC50 = 0.39 µM | PMID: 17524643 | |||
ZINC28948386 | agonist | Compound 2 | EC50 = 20 µM | PMID: 17379517 |
|
||
ZINC28948388 | agonist | Compound 3 | EC50 = 1.4 µM | PMID: 17379517 |
|
||
ZINC28948390 | agonist | Compound 4 | EC50 = 13 µM | PMID: 17379517 |
|
||
ZINC28948392 | agonist | Compound 5 | EC50 = 7.9 µM | PMID: 17379517 |
|
||
ZINC28948394 | agonist | Compound 6 | EC50 = 4.0 µM | PMID: 17379517 |
|
||
ZINC28948396 | agonist | Compound 7 | EC50 = 6.0 µM | PMID: 17379517 |
|
||
ZINC28948398 | agonist | Compound 8 | EC50 = 4.0 µM | PMID: 17379517 |
|
||
ZINC28948415 | agonist | Compound 10 | EC50 = 3 µM | PMID: 17379517 | PPAR_gamma | ||
ZINC28948819 | agonist | Compound 9 | EC50 = 15 µM | PMID: 17379517 |
|
||
ZINC28954798 | agonist | Compound 1 | EC50 = 0.05 µM | PMID: 17560785 | |||
ZINC28954799 | agonist | Compound 2 | EC50 = 0.13 µM | PMID: 17560785 | |||
ZINC28978854 | agonist | Compound 14 | EC50 = 0.4 µM | PMID: 18060776 |
|
||
ZINC29057355 | agonist | Compound 79 | EC50 = 3 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29057646 | agonist | Compound 75 | EC50 = 9 nM | PMID: 18155554 |
|
||
ZINC29057804 | agonist | Compound 66 | EC50 = 229 nM | PMID: 18155554 | |||
ZINC29057808 | agonist | Compound 70 | EC50 = 2 nM | PMID: 18155554 |
|
||
ZINC29057968 | agonist | Compound 62 | EC50 = 237 nM | PMID: 18155554 | |||
ZINC29058101 | agonist | Compound 55 | EC50 = 25 nM | PMID: 18155554 |
|
||
ZINC29058105 | agonist | Compound 50 | EC50 = 93 nM | PMID: 18155554 | |||
ZINC29058241 | agonist | Compound 45 | EC50 = 102 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29058249 | agonist | Compound 40 | EC50 = 8 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29058367 | agonist | Compound 30 | EC50 = 5 nM | PMID: 18155554 |
|
||
ZINC29058372 | agonist | Compound 35 | EC50 = 3 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29058615 | agonist | Compound 20 | EC50 = 2 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29058739 | agonist | Compound 13 | EC50 = 150 nM | PMID: 18155554 | |||
ZINC29058743 | agonist | Compound 16 | EC50 = 20 nM | PMID: 18155554 | |||
ZINC29058747 | agonist | Compound 10 | EC50 = 5 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29058857 | agonist | Compound 6 | EC50 = 2 nM | PMID: 18155554 | |||
ZINC29059179 | agonist | Compound 86 | EC50 = 20 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29059200 | agonist | Compound 82 | EC50 = 534 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29059206 | agonist | Compound 83 | EC50 = 148 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29059402 | agonist | Compound 80 | EC50 = 13 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29059409 | agonist | Compound 81 | EC50 = 114 nM | PMID: 18155554 | PPAR_alpha | ||
ZINC29127122 | agonist | Compound 13 | EC50 = 870 nM | PMID: 18162399 |
|
||
ZINC29127161 | agonist | Compound 12 | EC50 = 120 nM | PMID: 18162399 |
|
||
ZINC29132176 | agonist | Compound 20 | EC50 (%inhibition) = 20.2 | PMID: 18083521 |
|
||
ZINC29132182 | agonist | Compound 18 | EC50 (%inhibition) = 8.4 | PMID: 18083521 |
|
||
ZINC29132184 | agonist | Compound 19 | EC50 (%inhibition) = 29.6 | PMID: 18083521 |
|
||
ZINC29132261 | agonist | Compound 16 | EC50 (%inhibition) = 17.3 | PMID: 18083521 |
|
||
ZINC29132263 | agonist | Compound 17 | EC50 (%inhibition) = 9.6 | PMID: 18083521 |
|
||
ZINC29132264 | agonist | Compound 14 | EC50 (%inhibition) = 16.3 | PMID: 18083521 |
|
||
ZINC29132266 | agonist | Compound 15 | EC50 (%inhibition) = 19.3 | PMID: 18083521 |
|
||
ZINC29132642 | agonist | Compound 6 | EC50 (%inhibition) = 31.3 | PMID: 18083521 |
|
||
ZINC29132644 | agonist | Compound 7 | EC50 (%inhibition) = 29.1 | PMID: 18083521 |
|
||
ZINC29132646 | agonist | Compound 8 | EC50 (%inhibition) = 22.4 | PMID: 18083521 |
|
||
ZINC31157255 | agonist | Compound 2 | EC50 = 53.1 +/- 6.2 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC32207668 | agonist | Compound 12 | EC50 (%inhibition) = 24.6 | PMID: 18083521 |
|
||
ZINC33954913 | agonist | Compound 12/13 | EC50 = 51.1 +/- 5.6 µM | PMID: 22381047 | PPAR_gamma | ||
ZINC34001583 | agonist | Compound 4 | EC50 = 0.1 µM | PMID: 21515063 |
|
||
ZINC34044490 | agonist | Compound 5 | EC50 = 11 µM | PMID: 15713415 | PPAR_alpha | ||
ZINC34210397 | agonist | Compound 28 | IC50 = 0.892 µM | EC50 = 2.2 µM | PMID: 16737814 |
|
|
ZINC34251438 | agonist | Compound 5 | EC50 = 0.83 +/- 0.10 µM | PMID: 17343371 | |||
ZINC34393524 | agonist | Compound 14a | EC50 = 300 +/- 15 nM | PMID: 21530275 | PPAR_alpha | ||
ZINC34598050 | agonist | Compound (S)-4f | EC50 = 3.0 µM | PMID: 22133631 | PPAR_alpha | ||
ZINC34717672 | agonist | Compound 27 | IC50 = 0.259 µM | EC50 = 1.6 µM | PMID: 16737814 |
|
|
ZINC34717700 | agonist | Compound 18 | IC50 = 5 +/- 0 nM | EC50 = 73 +/- 6 nM | PMID: 16970391 |
|
|
ZINC34717701 | agonist | Compound 6 | IC50 = 6 +/- 0 nM | EC50 = 47 +/- 12 nM | PMID: 16970391 |
|
|
ZINC34717702 | agonist | Compound 17 | IC50 = 5 +/- 0 nM | EC50 = 1 +/- 0 nM | PMID: 16970391 |
|
|
ZINC34717703 | agonist | Compound 19 | IC50 = 4 +/- 0 nM | EC50 = 34 +/- 0 nM | PMID: 16970391 |
|
|
ZINC34717704 | agonist | Compound 20 | IC50 = 4 +/- 1 nM | EC50 = 6 +/- 0 nM | PMID: 16970391 |
|
|
ZINC34717709 | agonist | Compound 13 | IC50 = 8 +/- 0 nM | EC50 = 70 +/- 22 nM | PMID: 16970391 |
|
|
ZINC34717711 | agonist | Compound 15 | IC50 = 4 +/- 0 nM | EC50 = 8 +/- 3 nM | PMID: 16970391 |
|
|
ZINC34717712 | agonist | Compound 16 | IC50 = 5 +/- 0 nM | EC50 = 2 +/- 1 nM | PMID: 16970391 |
|
|
ZINC34867419 | agonist | Compound 28 | EC50 = 15 nM | PMID: 16797985 |
|
||
ZINC35065299 | agonist | Compound 9 | EC50 = 6.980 µM | PMID: 17034149 |
|
||
ZINC35246678 | agonist | Compound 14 | EC50 = 0.02 +/- 0.07 µM | PMID: 17243659 |
|
||
ZINC35246701 | agonist | Compound 34 | EC50 = 6.26 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC35246717 | agonist | Compound 25j | EC50 = 0.808 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC36411196 | agonist | Compound 29 | EC50 = 45.6 nM | PMID: 19168353 | |||
ZINC36757774 | agonist | Compound 23 | IC50 = 5 nM | EC50 = 19 nM | PMID: 11677135 |
|
|
ZINC36757831 | agonist | Compound 2 | EC50 = 0.97 µM | PMID: 16546385 | |||
ZINC36757832 | agonist | Compound 5 | EC50 = 0.56 µM | PMID: 16546385 | |||
ZINC36757833 | agonist | Compound 4 | EC50= 0.05 µM | PMID: 16546385 | PPAR_alpha | ||
ZINC36757863 | agonist | Compound 21a | EC50 = 0.004 µM | PMID: 16750626 | PPAR_alpha | ||
ZINC36757864 | agonist | Compound 24d | EC50 = 0.03 µM | PMID: 16750626 | PPAR_alpha | ||
ZINC36757865 | agonist | Compound 23 | EC50 = 7 nM | PMID: 16797985 |
|
||
ZINC36757866 | agonist | Compound 22 | EC50 = 16 nM | PMID: 16797985 |
|
||
ZINC36757867 | agonist | Compound 21 | EC50 = 98 nM | PMID: 16797985 |
|
||
ZINC36757868 | agonist | Compound 16 | EC50 = 82 nM | PMID: 16797985 |
|
||
ZINC36757869 | agonist | Compound 5 | EC50 = 457 nM | PMID: 16797985 |
|
||
ZINC36757871 | agonist | Compound 12 | EC50 = 4.630 µM | PMID: 17034149 |
|
||
ZINC36757876 | agonist | Compound 45 | EC50 = 8.24 +/- 1.75 µM | PMID: 17243659 |
|
||
ZINC37866897 | agonist | Compound 24 | EC50 = 0.03 µM | PMID: 16546385 | |||
ZINC37866898 | agonist | Compound 23 | EC50 = 0.04 µM | PMID: 16546385 | |||
ZINC37866899 | agonist | Compound 22 | EC50 = 0.21 µM | PMID: 16546385 | |||
ZINC37866900 | agonist | Compound 21 | EC50 = 0.04 µM | PMID: 16546385 | |||
ZINC37866901 | agonist | Compound 20 | EC50 = 0.09 µM | PMID: 16546385 | |||
ZINC37866902 | agonist | Compound 19 | EC50 = 0.11 µM | PMID: 16546385 | |||
ZINC37866903 | agonist | Compound 18 | EC50 = 0.06 µM | PMID: 16546385 | |||
ZINC37866904 | agonist | Compound 17 | EC50 = 0.07 µM | PMID: 16546385 | |||
ZINC37866905 | agonist | Compound 16 | EC50 = 0.07 µM | PMID: 16546385 | |||
ZINC37866906 | agonist | Compound 15 | EC50 = 0.06 µM | PMID: 16546385 | |||
ZINC37866907 | agonist | Compound 14 | EC50 = 0.56 µM | PMID: 16546385 | |||
ZINC37866908 | agonist | Compound 13 | EC50 = 0.03 µM | PMID: 16546385 | |||
ZINC37866909 | agonist | Compound 12 | EC50 = 0.11 µM | PMID: 16546385 | |||
ZINC37866910 | agonist | Compound 11 | EC50 = 0.49 µM | PMID: 16546385 | |||
ZINC37866912 | agonist | Compound 10 | EC50 = 0.35 µM | PMID: 16546385 | |||
ZINC37866913 | agonist | Compound 9 | EC50 = 0.16 µM | PMID: 16546385 | |||
ZINC37866915 | agonist | Compound 8 | EC50 = 0.54 µM | PMID: 16546385 | |||
ZINC37866916 | agonist | Compound 7 | EC50 = 0.03 µM | PMID: 16546385 | |||
ZINC37866917 | agonist | Compound 6 | EC50 = 0.07 µM | PMID: 16546385 | PPAR_alpha | ||
ZINC37866918 | agonist | Compound 1 | EC50 = 0.01 µM | PMID: 16546385 | |||
ZINC37866919 | agonist | Compound 3 | EC50 = 0.11 µM | PMID: 16546385 | PPAR_alpha | ||
ZINC37866926 | agonist | Compound 15 | EC50 = 0.13 µM | PMID: 16750626 | PPAR_alpha | ||
ZINC37866927 | agonist | Compound 21d | EC50 = 0.26 µM | PMID: 16750626 | |||
ZINC37866928 | agonist | Compound 21e | EC50 = 0.31 µM | PMID: 16750626 | |||
ZINC37866929 | agonist | Compound 24a | EC50 = 0.11 µM | PMID: 16750626 | |||
ZINC37866930 | agonist | Compound 24b | EC50 = 0.09 µM | PMID: 16750626 | PPAR_alpha | ||
ZINC37866931 | agonist | Compound 24c | EC50 = 2.59 µM | PMID: 16750626 | |||
ZINC37866932 | agonist | Compound 24e | EC50 = 0.01 µM | PMID: 16750626 | |||
ZINC37866933 | agonist | Compound 24f | EC50 = 0.08 µM | PMID: 16750626 | |||
ZINC37866934 | agonist | Compound 25 | EC50 = 3.67 µM | PMID: 16750626 | |||
ZINC37866935 | agonist | Compound 26 | EC50 = 0.19 µM | PMID: 16750626 | |||
ZINC37866936 | agonist | Compound 29a | EC50 = 0.03 µM | PMID: 16750626 | |||
ZINC37866938 | agonist | Compound 6 | EC50 = 1046 nM | PMID: 16797985 | |||
ZINC37866939 | agonist | Compound 17j | EC50 = 0.06 µM | PMID: 16931011 | |||
ZINC37866940 | agonist | Compound 17i | EC50 = 0.05 µM | PMID: 16931011 | |||
ZINC37866941 | agonist | Compound 17h | EC50 = 0.09 µM | PMID: 16931011 | |||
ZINC37866942 | agonist | Compound 17g | EC50 = 1.07 µM | PMID: 16931011 | |||
ZINC37866944 | agonist | Compound 17f | EC50 = 0.56 µM | PMID: 16931011 | |||
ZINC37866946 | agonist | Compound 17e | EC50 = 0.97 µM | PMID: 16931011 | |||
ZINC37866948 | agonist | Compound 17d | EC50 = 0.07 µM | PMID: 16931011 | |||
ZINC37866949 | agonist | Compound 17c | EC50 = 0.20 µM | PMID: 16931011 | |||
ZINC37866951 | agonist | Compound 17a | EC50 = 0.72 µM | PMID: 16931011 | |||
ZINC37866952 | agonist | Compound 41 | EC50 = 0.66 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC37866953 | agonist | Compound 25d | EC50 = 5.4 +/- 0.9 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC37866954 | agonist | Compound 25c | EC50 = 4.6 +/- 0.5 µM | PMID: 17243659 | PPAR_alpha | ||
ZINC37866959 | agonist | Compound 2 | EC50 = 0.52 +/- 0.02 µM | PMID: 17343371 | |||
ZINC37866960 | agonist | Compound 6 | EC50 = 2.3 +/- 0.1 µM | PMID: 17343371 | |||
ZINC37866961 | agonist | Compound 4 | EC50 = 1.1 +/- 0.1 µM | PMID: 17343371 | |||
ZINC37866962 | agonist | Compound 3 | EC50 = 5.9 +/- 0.5 µM | PMID: 17343371 | |||
ZINC38139028 | agonist | Compound 10 | Ki = 0.004 µM | EC50 = 0.054 µM | PMID: 19464171 |
|
|
ZINC38158119 | agonist | Compound 8b | EC50 = 10.50 +/- 2.27 µM | PMID: 14584939 |
|
||
ZINC38309475 | agonist | Compound 18 | EC50 = 46.7 nM | PMID: 19168353 | |||
ZINC38310496 | agonist | Compound 30 | EC50 = 1.060 µM | PMID: 18947994 |
|
||
ZINC38320570 | agonist | Compound 8 | EC50 = 1.360 µM | PMID: 18947994 |
|
||
ZINC38323523 | agonist | Compound 25 | EC50 = 1.550 µM | PMID: 18947994 |
|
||
ZINC40379961 | agonist | Compound 12 | EC50 = 2.700 µM | PMID: 18947994 |
|
||
ZINC40380487 | agonist | Compound 10 | EC50 = 2.870 µM | PMID: 18947994 |
|
||
ZINC40391278 | agonist | Compound 16 | EC50 = 2.05 µM | PMID: 18947994 |
|
||
ZINC40391945 | agonist | Compound 27 | EC50 = 35.4 nM | PMID: 19168353 | |||
ZINC40392616 | agonist | Compound 14 | EC50 = 1.150 µM | PMID: 18947994 |
|
||
ZINC40393734 | agonist | Compound 6 | EC50 = 2.165 µM | PMID: 18947994 |
|
||
ZINC40401175 | agonist | Compound 12 | EC50 = 54.3 nM | PMID: 19168353 | |||
ZINC40401517 | agonist | Compound 7 | EC50 = 216 nM | PMID: 19168353 | |||
ZINC40401630 | agonist | Compound 3 | EC50 = 65.5 nM | PMID: 19168353 | |||
ZINC40423329 | agonist | Compound 5 | pIC50 = 8.1 | PEC50 = 6.7 | PMID: 18722772 | ||
ZINC40424157 | agonist | Compound 36 | pIC50 = 7.8 | PEC50 = 7.8 | PMID: 18722772 | ||
ZINC40424310 | agonist | Compound 33 | pIC50 = 8.2 | PEC50 = 6.8 | PMID: 18722772 | ||
ZINC40424339 | agonist | Compound 22 | pIC50 = 8.0 | PEC50 = 7.4 | PMID: 18722772 | ||
ZINC40425282 | agonist | Compound 24 | pIC50 = 7.7 | PEC50 = 7.3 | PMID: 18722772 | ||
ZINC40428667 | agonist | Compound 13 | pIC50 = 8.4 | PEC50 = 5.9 | PMID: 18722772 | ||
ZINC40429259 | agonist | Compound 20 | pIC50 = 8.2 | PEC50 = 7.7 | PMID: 18722772 | ||
ZINC40430131 | agonist | Compound 28 | pIC50 = 7.5 | PEC50 = 7.0 | PMID: 18722772 | ||
ZINC40430607 | agonist | Compound 27 | pIC50 = 7.2 | PEC50 = 6.7 | PMID: 18722772 | ||
ZINC40430870 | agonist | Compound 31 | pIC50 = 7.3 | PEC50 = 6.2 | PMID: 18722772 | ||
ZINC40827704 | agonist | Compound 25 | EC50 = 69.6 nM | PMID: 19168353 | |||
ZINC40834180 | agonist | Compound 7b | Transactivation = 1.2 | PMID: 18805005 | PPAR_gamma | ||
ZINC40847207 | agonist | Compound 4 | EC50 = 10 µM | PMID: 18947994 |
|
||
ZINC40860845 | agonist | Compound 26 | EC50 = 45.5 nM | PMID: 19168353 | |||
ZINC40861449 | agonist | Compound 28 | EC50 = 147 nM | PMID: 19168353 | |||
ZINC40865299 | agonist | Compound 22 | EC50 = 249 nM | PMID: 19168353 | |||
ZINC40891654 | agonist | Compound 29 | EC50 = 0.035 µM | PMID: 18947994 |
|
||
ZINC40892035 | agonist | Compound 8 | EC50 = 238 nM | PMID: 19168353 | |||
ZINC40894891 | agonist | Compound 2 | EC50 = 711 nM | PMID: 19168353 | |||
ZINC40894894 | agonist | Compound 4 | EC50 = 49.8 nM | PMID: 19168353 | |||
ZINC40896724 | agonist | Compound 9 | EC50 = 138 nM | PMID: 19168353 | |||
ZINC40943237 | agonist | Compound 11 | pIC50 = 7.9 | PEC50 = 5.9 | PMID: 18722772 | ||
ZINC40943239 | agonist | Compound 12 | pIC50 = 7.7 | PEC50 = 5.7 | PMID: 18722772 | ||
ZINC40943241 | agonist | Compound 8 | pIC50 = 8.3 | PEC50 = 6.8 | PMID: 18722772 | ||
ZINC40954668 | agonist | Compound 2 | pIC50 = 7.9 | PEC50 = 6.7 | PMID: 18722772 | ||
ZINC40956316 | agonist | Compound 29 | pIC50 = 8.4 | PEC50 = 7.1 | PMID: 18722772 | ||
ZINC40957231 | agonist | Compound 21 | pIC50 = 8.0 | PEC50 = 7.9 | PMID: 18722772 | ||
ZINC40972730 | agonist | Compound 17 | pIC50 = 7.6 | PEC50 = 6.1 | PMID: 18722772 | ||
ZINC40973244 | agonist | Compound 26 | pIC50 = 8.0 | PEC50 = 7.3 | PMID: 18722772 | ||
ZINC40973797 | agonist | Compound 12 | Ki = 0.016 µM | EC50 = 1.1 µM | PMID: 19464171 | ||
ZINC40974062 | agonist | Compound 32 | pIC50 = 7.7 | PEC50 = 7.9 | PMID: 18722772 | ||
ZINC40974150 | agonist | Compound 35 | pIC50 = 7.9 | PEC50 = 7.0 | PMID: 18722772 | ||
ZINC40975332 | agonist | Compound 30 | pIC50 = 7.8 | PEC50 = 6.8 | PMID: 18722772 | ||
ZINC40975334 | agonist | Compound 37 | Ki = 0.12 µM | EC50= 1.5 µM | PMID: 19464171 | PPAR_gamma | |
ZINC40975457 | agonist | Compound 34 | pIC50 = 7.9 | PEC50 = 6.8 | PMID: 18722772 | ||
ZINC40975519 | agonist | Compound 25 | pIC50 = 6.8 | PEC50 = 6.3 | PMID: 18722772 | ||
ZINC40975644 | agonist | Compound 18 | pIC50 = 7.8 | PEC50 = 6.5 | PMID: 18722772 | ||
ZINC40976022 | agonist | Compound 23 | pIC50 = 8.0 | PEC50 = 7.5 | PMID: 18722772 | ||
ZINC40976208 | agonist | Compound 36 | Ki = 0.15 µM | EC50= 0.90 µM | PMID: 19464171 | PPAR_gamma | |
ZINC40976330 | agonist | Compound 15 | pIC50 = 8.0 | PEC50 = 6.1 | PMID: 18722772 | ||
ZINC40976332 | agonist | Compound 16 | pIC50 = 7.8 | PEC50 = 6.0 | PMID: 18722772 | ||
ZINC40979112 | agonist | Compound 7e | Transactivation = 2.2 | PMID: 18805005 | PPAR_gamma | ||
ZINC42804577 | agonist | Compound 14 | Ki = 0.036 µM | EC50 = 2.9 µM | PMID: 19464171 | ||
ZINC42804863 | agonist | Compound 20 | Ki = 0.006 µM | EC50= 0.043 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42804868 | agonist | Compound 21 | Ki = 0.005 µM | EC50= 0.044 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42804942 | agonist | Compound 25 | Ki = 0.006 µM | EC50= 1.2 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42806443 | agonist | Compound 34 | Ki = 0.66 µM | EC50= 3.1 µM | PMID: 19464171 | ||
ZINC42807188 | agonist | Compound 26 | Ki = 0.009 µM | EC50= 0.34 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42807442 | agonist | Compound 15 | Ki = 0.047 µM | EC50 = 4.1 µM | PMID: 19464171 | ||
ZINC42807859 | agonist | Compound 33 | Ki = 0.011 µM | EC50= 1.2 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42834793 | agonist | Compound 28 | Ki = 0.016 µM | EC50= 0.68 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42835651 | agonist | Compound 22 | Ki = 0.022 µM | EC50= 1.4 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42851344 | agonist | Compound 28 | EC50 = 2000 nM | PMID: 19275963 | PPAR_gamma | ||
ZINC42851547 | agonist | Compound 27 | Ki = 0.004 µM | EC50= 0.47 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42875255 | agonist | Compound (S)-4l | EC50 = 25 +/- 2 nM | PMID: 18662876 |
|
||
ZINC42888208 | agonist | Compound 6 | pIC50 = 7.6 | PEC50 = 6.3 | PMID: 18722772 | ||
ZINC42889354 | agonist | Compound 7 | pIC50 = 8.3 | PEC50 = 6.8 | PMID: 18722772 | ||
ZINC42890929 | agonist | Compound 7d | Transactivation = 1.2 | PMID: 18805005 | PPAR_gamma | ||
ZINC42920692 | agonist | Compound 23 | Ki = 0.002 µM | EC50= 0.22 µM | PMID: 19464171 | PPAR_gamma | |
ZINC42921106 | agonist | Compound 25 | EC50 = 11.2 +/- 0.45 µM | PMID: 19556125 |
|
||
ZINC42921866 | agonist | Compound 13 | Ki = 0.035 µM | EC50 =2.2 µM | PMID: 19464171 | ||
ZINC43022184 | agonist | Compound 21 | EC50 =1.4 +/- 0.38 µM | PMID: 19556125 |
|
||
ZINC43277624 | antagonist | gsk0660 | pIC50 = 6.8 | pIC50 = 6.5 | PMID: 20128594 | ||
ZINC43640915 | agonist | Compound 5 | EC50 (%inhibition) = 8.9 | PMID: 18083521 |
|
||
ZINC44280935 | agonist | Compound 20 | EC50 = 500 nM | PMID: 19275963 |
|
||
ZINC44359368 | agonist | Compound (R)-4l | EC50 = 180 +/- 10 nM | PMID: 18662876 |
|
||
ZINC45355352 | antagonist | Compound 16 | pIC50 = 7.3 | pIC50 = 7.1 | PMID: 20128594 | ||
ZINC45357049 | antagonist | Compound 10 | pIC50 = 6.7 | pIC50 = 6.6 | PMID: 20128594 | ||
ZINC45357936 | antagonist | Compound 12 | PIc50 = 6.5 | pIC50 = 6.7 | PMID: 20128594 | ||
ZINC45358296 | antagonist | Compound 13 | pIC50 = 6.8 | pIC50 = 6.7 | PMID: 20128594 | ||
ZINC45393353 | antagonist | Compound 15 | pIC50 = 6.9 | pIC50 = 6.6 | PMID: 20128594 | ||
ZINC45394247 | antagonist | Compound 14 | pIC50 = 6.9 | pIC50 = 6.6 | PMID: 20128594 | ||
ZINC45495691 | agonist | Compound 11 | Transactivation = 1.4 | PMID: 18805005 | PPAR_gamma | ||
ZINC45496383 | agonist | Compound 7a | Transactivation = 1.1 | PMID: 18805005 | PPAR_gamma | ||
ZINC45497359 | agonist | Compound 7g | Transactivation = 2.2 | PMID: 18805005 | PPAR_gamma | ||
ZINC45505696 | agonist | Compound 13 | EC50 = 5.27 µM | PMID: 19301897 |
|
||
ZINC45506275 | agonist | Compound 16 | EC50 = 4.45 µM | PMID: 19301897 |
|
||
ZINC45506726 | agonist | Compound 7c | Transactivation = 1.9 | PMID: 18805005 | PPAR_gamma | ||
ZINC48957410 | agonist | Compound 25n | EC50 = 6.32 µM | PMID: 19928766 | |||
ZINC49020965 | agonist | Compound 29a | EC50 = 0.06 µM | PMID: 19928766 | |||
ZINC49021299 | agonist | Compound 29ae | EC50 = 0.01 µM | PMID: 19928766 | |||
ZINC49021302 | agonist | Compound 29af | EC50 = 0.01 µM | PMID: 19928766 | |||
ZINC49021465 | agonist | Compound 25d | EC50 = 4.06 µM | PMID: 19928766 | PPAR_alpha | ||
ZINC49021468 | agonist | Compound 25f | EC50 = 0.34 µM | PMID: 19928766 | PPAR_alpha | ||
ZINC49021474 | agonist | Compound 29o | EC50 = 0.05 µM | PMID: 19928766 | |||
ZINC49021949 | agonist | Compound 38b | EC50 = 0.059 µM | PMID: 19928766 | |||
ZINC49031221 | agonist | Compound 29m | EC50 = 0.02 µM | PMID: 19928766 | |||
ZINC49031224 | agonist | Compound 25j | EC50 = 0.19 µM | PMID: 19928766 | |||
ZINC49031578 | agonist | Compound 46 | EC50 = 0.008 µM | PMID: 19928766 | |||
ZINC49032067 | agonist | Compound 29p | EC50 = 0.11 µM | PMID: 19928766 | |||
ZINC49032271 | agonist | Compound 3g | EC50 = 53 nM | PMID: 19853439 | |||
ZINC49032457 | agonist | Compound 3f | EC50 = 400 nM | PMID: 19853439 | |||
ZINC49032711 | agonist | Compound 47 | EC50 = 0.009 µM | PMID: 19928766 | |||
ZINC49032857 | agonist | Compound 29i | EC50 = 0.51 µM | PMID: 19928766 | |||
ZINC49032859 | agonist | Compound 29j | EC50 = 0.72 µM | PMID: 19928766 | |||
ZINC49032952 | agonist | Compound 38aa | EC50 = 0.007 µM | PMID: 19928766 | |||
ZINC49033165 | agonist | Compound 20 | EC50 = 0.12 µM | PMID: 19928766 | |||
ZINC49033169 | agonist | Compound 40a | EC50 = 0.93 µM | PMID: 19928766 | |||
ZINC49033389 | agonist | Compound 3k | EC50 = 14 nM | PMID: 19853439 | |||
ZINC49033496 | agonist | Compound 40p | EC50 = 1.30 µM | PMID: 19928766 | |||
ZINC49033502 | agonist | Compound 38a | EC50 = 0.068 µM | PMID: 19928766 | |||
ZINC49033534 | agonist | Compound 12 | EC50 = 1.41 µM | PMID: 19928766 | |||
ZINC49033614 | agonist | Compound 25g | EC50 = 1.39 µM | PMID: 19928766 | |||
ZINC49033947 | agonist | Compound 3i | EC50 = 45 nM | PMID: 19853439 | |||
ZINC49033981 | antagonist | Compound 3a | IC50 = 68 nM | PMID: 19853439 | |||
ZINC49033983 | agonist | Compound 3b | EC50 = 29 nM | PMID: 19853439 | PPAR_alpha | ||
ZINC49034017 | agonist | Compound 13 | EC50 = 6.36 µM | PMID: 19928766 | |||
ZINC49034019 | agonist | Compound 17 | EC50 = 0.81 µM | PMID: 19928766 | |||
ZINC49034093 | agonist | Compound 25u | EC50 = 2.62 µM | PMID: 19928766 | |||
ZINC49034095 | agonist | Compound 25v | EC50 = 0.13 µM | PMID: 19928766 | |||
ZINC49034149 | agonist | Compound 40q | EC50 = 0.14 µM | PMID: 19928766 | |||
ZINC49034173 | agonist | Compound 25t | EC50 = 0.51 µM | PMID: 19928766 | |||
ZINC49034220 | agonist | Compound 22 | EC50 = 0.66 µM | PMID: 19928766 | |||
ZINC49034344 | agonist | Compound 21 | EC50 = 0.25 µM | PMID: 19928766 | |||
ZINC49034831 | antagonist | Compound 3h | IC50 = 10 nM | PMID: 19853439 | |||
ZINC49034831 | agonist | Compound 19 | EC50 = 11 nM | PMID: 20843696 | |||
ZINC49035153 | agonist | Compound 9 | EC50 = 5.67 µM | PMID: 19928766 | |||
ZINC49035427 | agonist | Compound 29ac | EC50 = 0.65 µM | PMID: 19928766 | |||
ZINC49035452 | agonist | Compound 29ag | EC50 = 0.11 µM | PMID: 19928766 | |||
ZINC49036299 | agonist | Compound 25h | EC50 = 2.40 µM | PMID: 19928766 | |||
ZINC49036319 | agonist | Compound 16 | EC50 = 0.10 µM | PMID: 19928766 | |||
ZINC49036963 | agonist | Compound 29aa | EC50 = 0.05 µM | PMID: 19928766 | |||
ZINC49037259 | agonist | Compound 29ab | EC50 = 0.01 µM | PMID: 19928766 | |||
ZINC49045411 | agonist | Compound 25q | EC50 = 0.19 µM | PMID: 19928766 | |||
ZINC49045871 | agonist | Compound 29g | EC50 = 0.88 µM | PMID: 19928766 | |||
ZINC49055310 | agonist | Compound 3l | EC50 = 4.9 nM | PMID: 19853439 | |||
ZINC49109574 | agonist | Compound 24 | EC50 = 1.6 nM | PMID: 20843696 | PPAR_alpha | ||
ZINC49547509 | agonist | Compound 25e | EC50 = 4.71 µM | PMID: 19928766 | |||
ZINC49590143 | agonist | Compound 38g | EC50 = 0.018 µM | PMID: 19928766 | |||
ZINC49774630 | agonist | Compound 38ae | EC50 = 0.003 µM | PMID: 19928766 | |||
ZINC49774733 | agonist | Compound 10 | EC50 = 3.30 µM | PMID: 19928766 | |||
ZINC49774737 | agonist | Compound 35aa | EC50 = 0.003 µM | PMID: 19928766 | |||
ZINC49774796 | agonist | Compound 35e | EC50 = 0.032 µM | PMID: 19928766 | |||
ZINC49774807 | agonist | Compound 35j | EC50 = 0.063 µM | PMID: 19928766 | |||
ZINC49774853 | agonist | Compound 45 | EC50 = 0.018 µM | PMID: 19928766 | |||
ZINC49774863 | agonist | Compound 38c | EC50 =0.017 µM | PMID: 19928766 | |||
ZINC49774870 | agonist | Compound 35h | EC50 = 0.007 µM | PMID: 19928766 | |||
ZINC49774877 | agonist | Compound 40m | EC50 = 0.34 µM | PMID: 19928766 | |||
ZINC49774968 | agonist | Compound 38ad | EC50 = 0.014 µM | PMID: 19928766 | |||
ZINC49775005 | agonist | Compound 40s | EC50 = 0.062 µM | PMID: 19928766 | |||
ZINC49775008 | agonist | Compound 25i | EC50 = 0.35 µM | PMID: 19928766 | |||
ZINC49775068 | agonist | Compound 35c | EC50 = 0.056 µM | PMID: 19928766 | |||
ZINC49775072 | agonist | Compound 29e | EC50 = 0.02 µM | PMID: 19928766 | |||
ZINC49775199 | agonist | Compound 40j | EC50 = 0.38 µM | PMID: 19928766 | |||
ZINC49775280 | agonist | Compound 19 | EC50 = 0.03 µM | PMID: 19928766 | |||
ZINC49775364 | agonist | Compound 35a | EC50 = 0.331 µM | PMID: 19928766 | |||
ZINC49775368 | agonist | Compound 29f | EC50 = 0.15 µM | PMID: 19928766 | |||
ZINC49775414 | agonist | Compound 40k | EC50 = 2.93 µM | PMID: 19928766 | |||
ZINC49775436 | agonist | Compound 29c | EC50 = 0.07 µM | PMID: 19928766 | |||
ZINC49775452 | agonist | Compound 35t | EC50 = 0.544 µM | PMID: 19928766 | |||
ZINC49775480 | agonist | Compound 29h | EC50 = 0.13 µM | PMID: 19928766 | |||
ZINC49775727 | agonist | Compound 29k | EC50 = 0.01 µM | PMID: 19928766 | |||
ZINC49777045 | agonist | Compound 40r | EC50 = 0.48 µM | PMID: 19928766 | |||
ZINC49777254 | agonist | Compound 29ad | EC50 = 0.01 µM | PMID: 19928766 | |||
ZINC49777284 | agonist | Compound 38ac | EC50 = 0.008 µM | PMID: 19928766 | |||
ZINC49777854 | agonist | Compound 44 | EC50 = 0.009 µM | PMID: 19928766 | |||
ZINC49778048 | agonist | Compound 35k | EC50 = 0.010 µM | PMID: 19928766 | |||
ZINC49778049 | agonist | Compound 35ac | EC50 = 0.004 µM | PMID: 19928766 | |||
ZINC49778062 | agonist | Compound 38ah | EC50 = 0.001 µM | PMID: 19928766 | |||
ZINC49778097 | agonist | Compound 38h | EC50 = 0.003 µM | PMID: 19928766 | |||
ZINC49780201 | agonist | Compound 35q | EC50 = 0.052 µM | PMID: 19928766 | |||
ZINC49781223 | agonist | Compound 35p | EC50 = 0.410 µM | PMID: 19928766 | |||
ZINC49781224 | agonist | Compound 35r | EC50 = 0.045 µM | PMID: 19928766 | |||
ZINC49781271 | agonist | Compound 35w | EC50 = 0.006 µM | PMID: 19928766 | PPAR_gamma | ||
ZINC49785222 | agonist | Compound 35n | EC50 = 0.013 µM | PMID: 19928766 | |||
ZINC49785234 | agonist | Compound 38af | EC50 = 0.001 µM | PMID: 19928766 | |||
ZINC49785235 | agonist | Compound 35m | EC50 = 0.017 µM | PMID: 19928766 | |||
ZINC49785236 | agonist | Compound 35f | EC50 = 0.035 µM | PMID: 19928766 | |||
ZINC49785269 | agonist | Compound 40d | EC50 = 1.20 µM | PMID: 19928766 | |||
ZINC49785293 | agonist | Compound 35s | EC50 = 0.775 µM | PMID: 19928766 | |||
ZINC49785294 | agonist | Compound 35d | EC50 = 0.120 µM | PMID: 19928766 | |||
ZINC49785329 | agonist | Compound 38e | EC50 = 0.008 µM | PMID: 19928766 | |||
ZINC49785395 | agonist | Compound 40g | EC50 = 2.26 µM | PMID: 19928766 | |||
ZINC49785399 | agonist | Compound 41 | EC50 = 0.011 µM | PMID: 19928766 | |||
ZINC49785492 | agonist | Compound 25p | EC50 = 0.32 µM | PMID: 19928766 | |||
ZINC49785525 | agonist | Compound 29n | EC50 = 0.08 µM | PMID: 19928766 | |||
ZINC49785558 | agonist | Compound 29b | EC50 = 0.04 µM | PMID: 19928766 | |||
ZINC49785878 | agonist | Compound 35g | EC50 = 0.026 µM | PMID: 19928766 | |||
ZINC49785899 | agonist | Compound 29ah | EC50 = 0.07 µM | PMID: 19928766 | |||
ZINC49792537 | agonist | Compound 25k | EC50 = 5.90 µM | PMID: 19928766 | |||
ZINC49792547 | agonist | Compound 40f | EC50 = 0.02 µM | PMID: 19928766 | |||
ZINC49792614 | agonist | Compound 38f | EC50 = 0.006 µM | PMID: 19928766 | |||
ZINC49792665 | agonist | Compound 35u | EC50 = 0.023 µM | PMID: 19928766 | |||
ZINC49792711 | agonist | Compound 40l | EC50 = 0.74 µM | PMID: 19928766 | |||
ZINC49792836 | agonist | Compound 18 | EC50 = 0.47 µM | PMID: 19928766 | |||
ZINC49792971 | agonist | Compound 40i | EC50 = 0.14 µM | PMID: 19928766 | |||
ZINC49792990 | agonist | Compound 35o | EC50 = 0.030 µM | PMID: 19928766 | |||
ZINC49793004 | agonist | Compound 38d | EC50 = 0.034 µM | PMID: 19928766 | |||
ZINC49793135 | agonist | Compound 43 | EC50 = 0.011 µM | PMID: 19928766 | |||
ZINC49793139 | agonist | Compound 40h | EC50 = 0.23 µM | PMID: 19928766 | |||
ZINC49793140 | agonist | Compound 38ab | EC50 = 0.055 µM | PMID: 19928766 | |||
ZINC49799640 | agonist | Compound 25s | EC50 = 0.13 µM | PMID: 19928766 | |||
ZINC49799645 | agonist | Compound 38ag | EC50 = 0.002 µM | PMID: 19928766 | |||
ZINC49803976 | agonist | Compound 35v | EC50 = 0.002 µM | PMID: 19928766 | PPAR_gamma | ||
ZINC49803977 | agonist | Compound 35ab | EC50 = 0.018 µM | PMID: 19928766 | |||
ZINC49804003 | agonist | Compound 35ad | EC50 = 0.001 µM | PMID: 19928766 | PPAR_gamma | ||
ZINC49850902 | agonist | Compound 29q | EC50 = 0.25 µM | PMID: 19928766 | |||
ZINC49864992 | agonist | Compound 35b | EC50 = 0.160 µM | PMID: 19928766 | |||
ZINC49867778 | agonist | Compound 32 | Ki = 0.028 µM | EC50= 0.37 µM | PMID: 19464171 | PPAR_gamma | |
ZINC49872280 | agonist | Compound 31 | Ki = 0.036 µM | EC50= 0.35 µM | PMID: 19464171 | PPAR_gamma | |
ZINC49877890 | agonist | Compound 30 | Ki = 0.12 µM | EC50= 1.1 µM | PMID: 19464171 | PPAR_gamma | |
ZINC49881838 | agonist | Compound 9 | Ki = 0.008 µM | EC50 = 1.9 µM | PMID: 19464171 | ||
ZINC49881851 | agonist | Compound 11 | Ki = 0.011 µM | EC50 = 1.7 µM | PMID: 19464171 | ||
ZINC49888670 | agonist | Compound 19 | Ki = 0.007 µM | EC50= 0.052 µM | PMID: 19464171 |
|
|
ZINC49888742 | agonist | Compound 29 | Ki = 0.035 µM | EC50= 0.42 µM | PMID: 19464171 | PPAR_gamma | |
ZINC49889090 | agonist | Compound 24 | Ki = 0.0006 µM | EC50= 2.0 µM | PMID: 19464171 | ||
ZINC53230851 | agonist | Compound 2e | PMID: 20403648 | ||||
ZINC53295731 | agonist | Compound 2i | PMID: 20403648 | ||||
ZINC60325686 | agonist | Compound 25 | EC50 = 2000 nM | PMID: 19275963 |
|
||
ZINC64245795 | agonist | Compound 25 | EC50 = 5.7 nM | PMID: 20843696 | |||
ZINC64251890 | agonist | Compound 26 | EC50 = 220 nM | PMID: 20843696 | PPAR_alpha | ||
ZINC64466848 | agonist | Compound 27 | EC50 = 76 nM | PMID: 20843696 | PPAR_alpha | ||
ZINC66099417 | agonist | Compound 12c | EC50 = 0.8 +/- 0.05 µM | PMID: 21215640 |
|
||
ZINC66100342 | agonist | Compound 6a | fold induction = 1.58 | PMID: 21195611 |
|
||
ZINC66100345 | agonist | Compound 6b | fold induction = 2.78 | PMID: 21195611 |
|
||
ZINC66100383 | agonist | Compound 6d | fold induction = 1.68 | PMID: 21195611 |
|
||
ZINC66100386 | agonist | Compound 6e | fold induction = 1.23 | PMID: 21195611 | PPAR_alpha | ||
ZINC66100388 | agonist | Compound 6f | fold induction = 1.62 | PMID: 21195611 |
|
||
ZINC66100753 | agonist | Compound (R)-19 | EC50 = 0.0005 µM | PMID: 21094606 | PPAR_alpha | ||
ZINC66100864 | agonist | Compound 6g | fold induction = 1.31 | PMID: 21195611 |
|
||
ZINC66101611 | agonist | Compound 12a | EC50 = 0.01 +/- 0.003 µM | PMID: 21215640 |
|
||
ZINC66112736 | agonist | Compound (S)-18 | EC50 = 0.005 µM | PMID: 21094606 | PPAR_alpha | ||
ZINC66166629 | agonist | Compound 18a | EC50 = 0.3 +/- 0.009 µM | PMID: 21215640 |
|
||
ZINC66251285 | agonist | Compound 20 | EC50 = 0.025 µM | PMID: 21112784 | |||
ZINC66251343 | agonist | Compound 6h | fold induction = 1.46 | PMID: 21195611 |
|
||
ZINC66251537 | agonist | Compound 6i | fold induction = 1.25 | PMID: 21195611 |
|
||
ZINC66259488 | agonist | Compound 12f | EC50 = 0.7 +/- 0.09 µM | PMID: 21215640 |
|
||
ZINC66259489 | agonist | Compound 17a | EC50 = 0.8 +/- 0.07 µM | PMID: 21215640 |
|
||
ZINC66262036 | agonist | Compound 6k | fold induction = 1.31 | PMID: 21195611 |
|
||
ZINC71296921 | agonist | Compound 2 | pIC50 = 5.9 | PEC50 = 6.8 | PMID: 21414782 | ||
ZINC71297001 | agonist | Compound 3a (S) | pIC50 = 6.2 | PEC50 = 6.5 | PMID: 21414782 | ||
ZINC71297002 | agonist | Compound 3b (R) | pIC50 = 7.6 | PEC50 = 7.9 | PMID: 21414782 | ||
ZINC71317744 | agonist | Compound 12 | pIC50 = 7.9 | PEC50 = 8.7 | PMID: 21414782 | ||
ZINC71331069 | agonist | Compound 5 | EC50 = 0.011 µM | PMID: 21515063 |
|
||
ZINC71331954 | agonist | Compound 14b | EC50 = 580 +/- 20 nM | PMID: 21530275 | PPAR_alpha | ||
ZINC71332043 | agonist | Compound 12 | EC50 = 2.0 µM | PMID: 21515063 |
|
||
ZINC71334180 | agonist | Compound 16 | EC50 = 0.7 µM | PMID: 21515063 |
|
||
ZINC71340511 | agonist | Compound 13 | EC50 = 0.9 µM | PMID: 21515063 |
|
||
ZINC71340668 | agonist | Compound 10 | EC50 = 1.3 µM | PMID: 21515063 |
|
||
ZINC71340789 | agonist | Compound 14c | EC50 = 800 +/- 30 nM | PMID: 21530275 | PPAR_alpha | ||
ZINC71340970 | agonist | Compound 18 | EC50 = 0.021 µM | PMID: 21515063 |
|
||
ZINC71341094 | agonist | Compound 15 | EC50 = 1.2 µM | PMID: 21515063 |
|
||
ZINC73313429 | agonist | Compound 4 | PMID: 22185225 |