Compound ID Pharmacological profile Compound name Binding data Activity data Bibliographic ref Cross-reactivity
CHEMBL110743 agonist Compound 14 IC50 = 0.36 µM EC50 = 0.03 µM PMID: 15163205 PPAR_gamma
CHEMBL111161 agonist Compound 26 IC50 = 4.0 µM EC50 = 0.21 µM PMID: 15163205 PPAR_gamma
CHEMBL111271 agonist Compound 25 IC50 = 0.97 µM EC50 = 0.01 µM PMID: 15163205 PPAR_gamma
CHEMBL111480 agonist Compound 40 IC50 = 0.12 µM EC50 = 0.08 µM PMID: 15163205 PPAR_gamma
CHEMBL112973 agonist Compound 38 IC50 = 0.37 µM EC50 = 0.05 µM PMID: 15163205 PPAR_gamma
CHEMBL116540 agonist Compound 68 EC50 = 0.043 µM PMID: 12904063 PPAR_beta
CHEMBL116947 agonist Compound 73 EC50 = 0.40 µM PMID: 12904063 PPAR_gamma
CHEMBL117402 agonist Compound 17 EC50 = 0.25 µM PMID: 15177462
PPAR_beta
CHEMBL117738 agonist Compound 9 IC50 = 0.062 µM EC50 = 0.17 µM PMID: 14505666 PPAR_gamma
CHEMBL118251 agonist Compound 14 IC50 = 0.61 µM EC50 = 0.054 µM PMID: 14505666 PPAR_gamma
CHEMBL118279 agonist Compound 77 EC50 = 5.6 µM PMID: 12904063 PPAR_gamma
CHEMBL118329 agonist Compound 46 EC50 = 0.02 µM PMID: 12904063
CHEMBL118483 agonist Compound 78 EC50 = 2.7 µM PMID: 12904063 PPAR_gamma
CHEMBL118492 agonist Compound 66 EC50 = 3.0 µM PMID: 12904063
CHEMBL118577 agonist Compound 19 EC50 = 0.09 µM PMID: 15177462
PPAR_beta
CHEMBL118756 agonist Compound 12 IC50 = 0.29 µM EC50 = 0.055 µM PMID: 14505666 PPAR_gamma
CHEMBL118816 agonist Compound 21 EC50 = 0.14 µM PMID: 15177462
PPAR_beta
CHEMBL118939 agonist Compound 17 EC50 = 10 nM PMID: 16275077
PPAR_beta
CHEMBL118976 agonist Compound 64 EC50 = 4.9 µM PMID: 12904063 PPAR_beta
CHEMBL119496 agonist Compound 8 IC50 = 0.12 µM EC50 = 0.13 µM PMID: 14505666 PPAR_gamma
CHEMBL119682 agonist Compound 70 EC50 = 3.1 µM PMID: 12904063
CHEMBL119791 agonist Compound 75 EC50 = 0.11 µM PMID: 12904063 PPAR_gamma
CHEMBL119911 agonist Compound 15 EC50 = 0.23 µM PMID: 12904063
CHEMBL120009 agonist Compound 2 EC50 = 70 nM PMID: 16275077
PPAR_beta
CHEMBL120243 agonist Compound 38 EC50 = 0.13 µM PMID: 12904063
CHEMBL120246 agonist Compound 12 EC50 = 0.29 µM PMID: 12904063
CHEMBL120444 agonist Compound 76 EC50 = 1.5 µM PMID: 12904063
CHEMBL120570 agonist Compound 2 IC50 = 1.4 µM EC50 = 0.035 µM PMID: 14505666 PPAR_gamma
CHEMBL1206087 agonist Compound 23a EC50 = 723 nM PMID: 16137885
CHEMBL1206089 agonist Compound 27a EC50 = 1485 nM PMID: 16137885
CHEMBL1206090 agonist Compound 15b EC50 = 1543 nM PMID: 16137885
CHEMBL120611 agonist Compound 19 EC50 = 0.74 µM PMID: 12904063 PPAR_beta
CHEMBL120620 agonist Compound 18 EC50 = 6.0 µM PMID: 12904063
CHEMBL120676 agonist Compound 71 EC50 = 1.2 µM PMID: 12904063 PPAR_beta
CHEMBL1207269 agonist Compound 23b EC50 = 114 nM PMID: 16137885 PPAR_gamma
CHEMBL120744 agonist Compound 16 EC50 = 1.6 µM PMID: 12904063
PPAR_beta
CHEMBL1208363 agonist Compound 13 EC50 = 0.160 +/- 0.022 µM PMID: 19775169 PPAR_gamma
CHEMBL1208366 agonist Compound 11 EC50 = 1.8 +/- 1.0 µM PMID: 19775169 PPAR_gamma
CHEMBL122009 agonist Compound 32 EC50 = 2.2 µM PMID: 12904063 PPAR_gamma
CHEMBL122070 agonist Compound 74 EC50 = 0.090 µM PMID: 12904063
PPAR_beta
CHEMBL1222408 agonist Compound 11d EC50 = 8.8 +/- 0.4 nM PMID: 21530275
PPAR_beta
CHEMBL122417 agonist Compound 11 IC50 = 0.08 µM EC50 = 0.053 µM PMID: 14505666 PPAR_gamma
CHEMBL122418 agonist Compound 10 IC50 = 0.46 µM EC50 = 0.076 µM PMID: 14505666 PPAR_gamma
CHEMBL147095 agonist Compound 14 PKi = 7.34 +/- 0.05 PEC50 = 6.24 +/- 0.41 PMID: 9836621 PPAR_gamma
CHEMBL147384 agonist Compound 11 PKi = 7.25 +/- 0.06 PEC50 = 6.59 +/- 0.07 PMID: 9836621 PPAR_gamma
CHEMBL148459 agonist Compound 13 Ki = 6.33 +/- 0.02 PEC50 = 5.56 +/- 0.17 PMID: 9836621 PPAR_gamma
CHEMBL148596 agonist Compound 19 pKi = 5.92 +/- 0.40 PEC50 = 5.19 +/- 0.60 PMID: 9836620
CHEMBL148797 agonist Compound 8 PKi = 6.76 +/- 0.03 PEC50 = 6.18 +/- 0.12 PMID: 9836621 PPAR_gamma
CHEMBL1630380 agonist Compound 1i EC50 = 15.2 nM PMID: 21074432
PPAR_beta
CHEMBL1630381 agonist Compound 1h EC50 = 83.1 nM PMID: 21074432 PPAR_beta
CHEMBL1630382 agonist Compound 1g EC50 = 120.0 nM PMID: 21074432 PPAR_beta
CHEMBL1630383 agonist Compound 2f EC50 = 350.3 nM PMID: 21074432 PPAR_beta
CHEMBL1630384 agonist Compound 2i EC50 = 24.6 nM PMID: 21074432
PPAR_beta
CHEMBL1630386 agonist Compound 2g EC50 = 39.4 nM PMID: 21074432 PPAR_beta
CHEMBL165539 agonist Compound 3i EC50 = 12.5 +/- 6.0 µM PMID: 11831892 PPAR_gamma
CHEMBL167352 agonist Compound 3n EC50 = 9.5 +/- 2.1 µM PMID: 11831892 PPAR_gamma
CHEMBL167378 agonist Compound 3b EC50 = 7.5 +/- 3.4 µM PMID: 11831892 PPAR_gamma
CHEMBL1779473 agonist Compound 11c EC50 = 12 +/- 3 nM PMID: 21530275 PPAR_beta
CHEMBL1779474 agonist Compound 11e EC50 = 41 +/- 4 nM PMID: 21530275 PPAR_beta
CHEMBL1779475 agonist Compound 11f EC50 = 3600 +/- 100 nM PMID: 21530275
CHEMBL1779476 agonist Compound 11h EC50 = 74 +/- 17 nM PMID: 21530275 PPAR_beta
CHEMBL1779477 agonist Compound 11i EC50 = 3600 +/- 300 nM PMID: 21530275
CHEMBL1779478 agonist Compound 11j EC50 = 52 +/- 16 nM PMID: 21530275 PPAR_beta
CHEMBL1779479 agonist Compound 11k EC50 = 60 +/- 13 nM PMID: 21530275 PPAR_beta
CHEMBL178158 agonist Compound 8 EC50 = 2.3 µM PMID: 15713415
CHEMBL1808551 antagonist Compound 4b IC50 = 31 +/- 1.8 µM PMID: 21742490
CHEMBL1808552 antagonist Compound 4c IC50 = 22.2 +/- 1.1 µM PMID: 21742490
CHEMBL1808553 antagonist Compound 4d IC50 = 27.9 +/- 1.6 µM PMID: 21742490
CHEMBL1808554 antagonist Compound 4e IC50 = 19.9 +/- 1.1 µM PMID: 21742490
CHEMBL1808555 agonist Compound 4f EC50 = 50.6 +/- 3.5 µM PMID: 21742490
CHEMBL1808556 antagonist Compound 4g IC50 = 6.5 +/- 0.3 µM PMID: 21742490
CHEMBL1813187 agonist Compound 10 EC50 = 33 µM PMID: 21514830
CHEMBL1813188 agonist Compound 11a EC50 = 11 µM PMID: 21514830
PPAR_beta
CHEMBL1813191 agonist Compound 12a EC50 = 29 µM PMID: 21514830 PPAR_beta
CHEMBL1813194 agonist Compound 13a EC50 = 6.6 µM PMID: 21514830
PPAR_beta
CHEMBL1813195 agonist Compound 13b EC50 = 14 µM PMID: 21514830
PPAR_beta
CHEMBL1813196 agonist Compound 13c EC50 = 3.4 µM PMID: 21514830
CHEMBL1813197 agonist Compound 13d EC50 = 1.4 µM PMID: 21514830
CHEMBL1813198 agonist Compound 13e EC50 = 1.7 µM PMID: 21514830
CHEMBL1813199 agonist Compound 13f EC50 = 1.8 µM PMID: 21514830
PPAR_beta
CHEMBL184133 agonist GW409544 Ki = 0.002 µM EC50 = 0.002 µM PMID: 15293980
CHEMBL189066 agonist Compound 36 IC50 = 0.16 µM EC50 = 0.16 µM PMID: 15974597 PPAR_gamma
CHEMBL190334 agonist Compound 36 IC50 = 0.004 µM EC50 = 0.015 µM PMID: 16107159
CHEMBL190968 agonist Compound 34 IC50 = 0.017 µM EC50 = 0.009 µM PMID: 16107159
CHEMBL191235 agonist Compound 30 IC50 = 0.13 µM EC50 = 0.16 µM PMID: 15974597
CHEMBL192500 agonist Compound 32 IC50 = 0.011 µM EC50 = 0.008 µM PMID: 16107159
CHEMBL192582 agonist Compound 21 IC50 = 0.106 µM EC50 = 0.138 µM PMID: 16107159
CHEMBL192609 agonist Compound 25 IC50 = 0.009 EC50 = 0.037 µM PMID: 16107159
CHEMBL192638 agonist Compound 23 IC50 = 0.032 µM EC50 = 0.034 µM PMID: 16107159
CHEMBL1927473 agonist Compound 2a EC50 = 3.7 +/- 0.8 nM PMID: 22051054 PPAR_beta
CHEMBL1927474 agonist Compound 2b EC50 = 5.0 +/- 1.1 nM PMID: 22051054 PPAR_beta
CHEMBL1927475 agonist Compound 2c EC50 = 31.4 +/- 5.1 nM PMID: 22051054 PPAR_beta
CHEMBL1934310 agonist Compound 2b EC50 = 0.76 µM PMID: 22133631
CHEMBL1934312 agonist Compound 4b EC50 = 0.85 µM PMID: 22133631
CHEMBL1934313 agonist Compound 4c EC50 = 0.7 µM PMID: 22133631
CHEMBL1934314 agonist Compound 4d EC50 = 0.81 µM PMID: 22133631
CHEMBL1934468 agonist Compound 8 EC50 = 0.28 µM PMID: 22133631
CHEMBL1934469 agonist Compound 9 EC50 = 3.4 µM PMID: 22133631
CHEMBL1934470 agonist Compound 10 EC50 = 2.4 µM PMID: 22133631
CHEMBL1934471 agonist Compound 11 EC50 = 0.25 µM PMID: 22133631
CHEMBL1934472 agonist Compound 12 EC50 = 0.12 µM PMID: 22133631
CHEMBL1934473 agonist Compound 13 EC50 = 0.81 µM PMID: 22133631
CHEMBL1934475 agonist Compound 5 EC50 = 1.5 µM PMID: 22133631
CHEMBL1934479 agonist Compound 14b EC50 = 1.5 µM PMID: 22133631
CHEMBL1934480 agonist Compound 14c EC50 = 0.072 µM PMID: 22133631 PPAR_beta
CHEMBL1934481 agonist Compound 14d EC50 = 0.026 µM PMID: 22133631 PPAR_beta
CHEMBL1934482 agonist Compound 14e EC50 = 0.053 µM PMID: 22133631 PPAR_beta
CHEMBL1934483 agonist Compound 14f EC50 = 0.021 µM PMID: 22133631 PPAR_beta
CHEMBL1934484 agonist Compound 14g EC50 = 0.006 µM PMID: 22133631 PPAR_beta
CHEMBL1934485 agonist Compound 14h EC50 = 0.023 µM PMID: 22133631 PPAR_beta
CHEMBL1934486 agonist Compound 14i EC50 = 0.037 µM PMID: 22133631
CHEMBL194698 agonist Compound 14a EC50 = 173 nM PMID: 16137885 PPAR_gamma
CHEMBL1956349 agonist Compound 14 EC50 = 5.1 +/- 0.1 µM PMID: 22341573 PPAR_gamma
CHEMBL1956350 agonist Compound 15 EC50 = 5.4 +/- 0.1 µM PMID: 22341573 PPAR_gamma
CHEMBL1956358 agonist Compound 4 EC50 = 21 +/- 7 µM PMID: 22341573 PPAR_gamma
CHEMBL1956359 agonist Compound 5 EC50 = 22.3 +/- 2.5 µM PMID: 22341573 PPAR_gamma
CHEMBL1956365 agonist Compound 11 EC50 = 6.5 +/- 1.6 µM PMID: 22341573 PPAR_gamma
CHEMBL1956366 agonist Compound 12 EC50 = 2.5 +/- 0.1 µM PMID: 22341573 PPAR_gamma
CHEMBL1956367 agonist Compound 13 EC50 = 6.6 +/- 0.1 µM PMID: 22341573 PPAR_gamma
CHEMBL1956368 agonist Compound 16 EC50 = 4.5 +/- 1.3 µM PMID: 22341573 PPAR_gamma
CHEMBL1956370 agonist Compound 18 EC50 = 19 +/- 8 µM PMID: 22341573 PPAR_gamma
CHEMBL1956371 agonist Compound 19 EC50 = 10.3 +/- 0.8 µM PMID: 22341573 PPAR_gamma
CHEMBL197684 agonist Compound 22b EC50 = 262 nM PMID: 16137885 PPAR_gamma
CHEMBL197866 agonist Compound 63 EC50 = 354 nM PMID: 16275080 PPAR_gamma
CHEMBL197971 agonist Compound 62 EC50 = 1130 nM PMID: 16275080 PPAR_gamma
CHEMBL198023 agonist Compound 60 EC50 = 46 nM PMID: 16275080 PPAR_gamma
CHEMBL198166 agonist Compound 22a EC50 = 1142 nM PMID: 16137885
CHEMBL198170 agonist Compound 25a EC50 = 1531 nM PMID: 16137885 PPAR_gamma
CHEMBL198288 agonist Compound 38 EC50 = 204 nM PMID: 16275080 PPAR_gamma
CHEMBL198708 agonist Compound 24a EC50 = 1454 nM PMID: 16137885
CHEMBL199339 agonist Compound 33 EC50 = 327 nM PMID: 16275080
CHEMBL199372 agonist Compound 65 EC50 = 5480 nM PMID: 16275080 PPAR_gamma
CHEMBL199432 agonist Compound 52 EC50 = 559 nM PMID: 16275080 PPAR_gamma
CHEMBL199449 agonist Compound 39 EC50 = 61 nM PMID: 16275080 PPAR_gamma
CHEMBL199459 agonist Compound 4 EC50 = 5790 nM PMID: 16275080 PPAR_gamma
CHEMBL199509 agonist Compound 36 EC50 = 23 nM PMID: 16275080 PPAR_gamma
CHEMBL199530 agonist Compound 32 EC50 = 181 nM PMID: 16275080
CHEMBL199559 agonist Compound 56 EC50 = 171 nM PMID: 16275080 PPAR_gamma
CHEMBL199579 agonist Compound 49 EC50 = 240 nM PMID: 16275080 PPAR_gamma
CHEMBL199645 agonist Compound 61 EC50 = 75 nM PMID: 16275080 PPAR_gamma
CHEMBL199703 agonist Compound 46 EC50 = 109 nM PMID: 16275080 PPAR_gamma
CHEMBL199794 agonist Compound 50 EC50 = 254 nM PMID: 16275080 PPAR_gamma
CHEMBL199819 agonist Compound 6 EC50 = 3890 nM PMID: 16275080 PPAR_gamma
CHEMBL199823 agonist Compound 2 EC50 = 6000 nM PMID: 16275080 PPAR_gamma
CHEMBL199855 agonist Compound 70 EC50 = 745 nM PMID: 16275080 PPAR_gamma
CHEMBL199928 agonist Compound 44 EC50 = 271 nM PMID: 16275080 PPAR_gamma
CHEMBL200043 agonist Compound 42 EC50 = 111 nM PMID: 16275080 PPAR_gamma
CHEMBL200045 agonist Compound 35 EC50 = 45 nM PMID: 16275080 PPAR_gamma
CHEMBL200071 agonist Compound 41 EC50 = 202 nM PMID: 16275080 PPAR_gamma
CHEMBL200122 agonist Compound 51 EC50 = 199 nM PMID: 16275080 PPAR_gamma
CHEMBL200138 agonist Compound 71 EC50 = 65 nM PMID: 16275080 PPAR_gamma
CHEMBL200207 agonist Compound 73 EC50 = 827 nM PMID: 16275080 PPAR_gamma
CHEMBL200304 agonist Compound 11j EC50 = 596 nM PMID: 17157019 PPAR_gamma
CHEMBL200495 agonist Compound 5 IC50 = 0.496 EC50 = 0.014 µM PMID: 16451087
PPAR_beta
CHEMBL200746 agonist Compound 27 EC50 = 383 nM PMID: 16275080 PPAR_gamma
CHEMBL200760 agonist Compound 28 EC50 = 354 nM PMID: 16275080 PPAR_gamma
CHEMBL200840 agonist Compound 11 EC50 = 670 nM PMID: 16275080 PPAR_gamma
CHEMBL200916 agonist Compound 72 EC50 = 287 nM PMID: 16275080 PPAR_gamma
CHEMBL200943 agonist Compound 31 EC50 = 127 nM PMID: 16275080 PPAR_gamma
CHEMBL201036 agonist Compound 10j IC50 = 0.578 µM EC50 = 0.019 µM PMID: 16451087 PPAR_gamma
CHEMBL201280 agonist Compound 34 EC50 = 58 nM PMID: 16275080 PPAR_gamma
CHEMBL201581 agonist Compound 10c IC50 = 0.116 µM EC50 = 0.765 µM PMID: 16451087 PPAR_beta
CHEMBL201653 agonist Compound 10d IC50 = 0.414 µM EC50 = 0.773 µM PMID: 16451087 PPAR_beta
CHEMBL201803 agonist Compound 10c EC50 = 25 nM PMID: 16275077
PPAR_beta
CHEMBL201832 agonist Compound 10b EC50 = 20 nM PMID: 16275077
PPAR_beta
CHEMBL201880 agonist Compound 10k IC50 = 0.113 µM EC50 = 0.008 µM PMID: 16451087
PPAR_beta
CHEMBL202246 agonist Compound 10l IC50 = 4.486 µM EC50 = 2.475 µM PMID: 16451087
PPAR_beta
CHEMBL202617 agonist Compound 10h IC50 = 0.484 µM EC50 = 0.270 µM PMID: 16451087
PPAR_beta
CHEMBL2113106 agonist Compound 24b EC50 = 1300 nM PMID: 16137885
CHEMBL2113107 agonist Compound 26a EC50 = 1194 nM PMID: 16137885
CHEMBL2113108 agonist Compound 26b EC50 = 1086 nM PMID: 16137885
CHEMBL2113109 agonist Compound 27b EC50 = 1399 nM PMID: 16137885
CHEMBL215127 agonist Compound 11 IC50 = 8919 +/- 0 nM EC50 = 2929 +/- 23 nM PMID: 16970391
PPAR_beta
CHEMBL215582 agonist Compound 7 IC50 = 1323 +/- 0 nM EC50 = 686 +/- 211 nM PMID: 16970391
PPAR_beta
CHEMBL229525 agonist Compound 10f EC50 = 140 +/- 20 nM PMID: 17532641
PPAR_beta
CHEMBL229573 agonist Compound 10g EC50 = 820 +/- 60 nM PMID: 17532641
PPAR_beta
CHEMBL229778 agonist Compound 5c EC50 = 77 +/- 11 nM PMID: 17532641
PPAR_beta
CHEMBL229785 agonist Compound 10b EC50 = 19 +/- 3 nM PMID: 17532641 PPAR_beta
CHEMBL229786 agonist Compound 10c EC50 = 70 +/- 21 nM PMID: 17532641
PPAR_beta
CHEMBL229831 agonist Compound 5e EC50 = 1200 +/- 300 nM PMID: 17532641
PPAR_beta
CHEMBL229836 agonist Compound 5i EC50 = 280 +/- 40 nM PMID: 17532641 PPAR_gamma
CHEMBL229837 agonist Compound 10e EC50 = 29 +/- 5 nM PMID: 17532641
PPAR_beta
CHEMBL229888 agonist Compound 10a EC50 = 210 +/- 40 nM PMID: 17532641 PPAR_beta
CHEMBL230305 agonist Compound 11k EC50 = 91 nM PMID: 17157019 PPAR_gamma
CHEMBL230409 agonist Compound 11m EC50 = 12 nM PMID: 17157019 PPAR_gamma
CHEMBL230410 agonist Compound 11o EC50 = 23 nM PMID: 17157019 PPAR_gamma
CHEMBL230411 agonist Compound 11p EC50 = 11.5 nM PMID: 17157019 PPAR_gamma
CHEMBL230517 agonist Compound 11q EC50 = 4 nM PMID: 17157019 PPAR_gamma
CHEMBL230518 agonist Compound 11r EC50 = 3.5 nM PMID: 17157019 PPAR_gamma
CHEMBL230519 agonist Compound 11t EC50 = 105 nM PMID: 17157019 PPAR_gamma
CHEMBL230622 agonist Compound 11u EC50 = 139 nM PMID: 17157019 PPAR_gamma
CHEMBL230623 agonist Compound 11v EC50 = 10 nM PMID: 17157019 PPAR_gamma
CHEMBL230705 agonist Compound 11e EC50 = 1.3 nM PMID: 17157019 PPAR_gamma
CHEMBL230706 agonist Compound 11f EC50 = 3.1 nM PMID: 17157019 PPAR_gamma
CHEMBL230707 agonist Compound 11g EC50 = 32 nM PMID: 17157019 PPAR_gamma
CHEMBL230814 agonist Compound 11h EC50 = 26 nM PMID: 17157019 PPAR_gamma
CHEMBL231425 agonist Compound 11a EC50 = 19 nM PMID: 17157019 PPAR_gamma
CHEMBL231523 agonist Compound 11c EC50 = 4.9 nM PMID: 17157019 PPAR_gamma
CHEMBL232798 agonist Compound 14 EC50 = 1.47 µM PMID: 17507225 PPAR_gamma
CHEMBL232799 agonist Compound 18 EC50 = 6.21 µM PMID: 17507225 PPAR_gamma
CHEMBL233003 agonist Compound (S)-9c EC50 = 0.88 µM PMID: 17507225 PPAR_gamma
CHEMBL233785 agonist Compound 9e EC50 = 20.40 µM PMID: 17507225 PPAR_gamma
CHEMBL234819 agonist Compound (S)-9a EC50 = 0.07 µM PMID: 17507225 PPAR_gamma
CHEMBL234820 agonist Compound (R)-9c EC50 = 2.77 µM PMID: 17507225 PPAR_gamma
CHEMBL234858 agonist Compound 9g EC50 = 7.26 µM PMID: 17507225 PPAR_gamma
CHEMBL234859 agonist Compound 9h EC50 = 10.70 µM PMID: 17507225 PPAR_gamma
CHEMBL234907 agonist Compound 6o EC50 = 5.8 µM PMID: 17553681 PPAR_beta
CHEMBL234908 agonist Compound 6q EC50 = 4.1 µM PMID: 17553681
PPAR_beta
CHEMBL238745 agonist Compound 20 EC50 = 4390 nM PMID: 17157013
CHEMBL238944 agonist Compound 21 EC50 = 3540 nM PMID: 17157013
CHEMBL238946 agonist Compound 22 EC50 = 2370 nM PMID: 17157013
CHEMBL239351 agonist Compound 10 EC50 = 6610 nM PMID: 17157013 PPAR_beta
CHEMBL239352 agonist Compound 12 EC50 = 200 nM PMID: 17157013
CHEMBL239353 agonist Compound 13 EC50 = 900 nM PMID: 17157013
CHEMBL239561 agonist Compound 14 EC50 = 641 nM PMID: 17157013
CHEMBL239562 agonist Compound 16 EC50 = 1390 nM PMID: 17157013
CHEMBL239563 agonist Compound 17 EC50 = 6550 nM PMID: 17157013
CHEMBL239771 agonist Compound 19 EC50 = 1130 nM PMID: 17157013
CHEMBL24038 agonist ragaglitazar IC50 = 0.98 +/- 0.04 EC50 = 3.2 µM PMID: 12672231 PMID : 15293980
CHEMBL245464 agonist Compound 30 EC50 = 0.023 µM PMID: 17553678
PPAR_beta
CHEMBL245465 agonist Compound 31 EC50 = 0.10 µM PMID: 17553678 PPAR_beta
CHEMBL245664 agonist Compound 34 EC50 = 0.18 µM PMID: 17553678 PPAR_beta
CHEMBL246069 agonist Compound 38 EC50 = 0.024 µM PMID: 17553678 PPAR_beta
CHEMBL246070 agonist Compound 40 EC50 = 0.001 µM PMID: 17553678
PPAR_beta
CHEMBL246281 agonist Compound 42 EC50 = 0.001 µM PMID: 17553678
PPAR_beta
CHEMBL246282 agonist Compound 43 EC50 = 0.011 µM PMID: 17553678
PPAR_beta
CHEMBL246510 agonist Compound 45 EC50 = 0.26 µM PMID: 17553678
PPAR_beta
CHEMBL248324 agonist Compound 23 EC50 = 0.01 µM PMID: 17553678
PPAR_beta
CHEMBL248326 agonist Compound 25 EC50 = 0.01 µM PMID: 17553678
PPAR_beta
CHEMBL248526 agonist Compound 26 EC50 = 0.05 µM PMID: 17553678
PPAR_beta
CHEMBL248527 agonist Compound 28 EC50 = 0.005 µM PMID: 17553678
PPAR_beta
CHEMBL248854 agonist Compound 23 EC50 = 2.09 µM PMID: 18029176
CHEMBL248855 agonist Compound 24 EC50 = 2.73 µM PMID: 18029176
CHEMBL249864 agonist Compound 34 EC50 = 2.85 µM PMID: 18029176
CHEMBL249867 agonist Compound 44 EC50 = 0.561 µM PMID: 18029176
CHEMBL249868 agonist Compound 45 EC50 = 0.105 µM PMID: 18029176
CHEMBL249869 agonist Compound 47 EC50 = 0.159 µM PMID: 18029176
CHEMBL249870 agonist Compound 52 EC50 = 0.249 µM PMID: 18029176
CHEMBL249871 agonist Compound 53 EC50 = 0.219 µM PMID: 18029176
CHEMBL249872 agonist Compound 60 EC50 = 0.598 µM PMID: 18029176
CHEMBL250036 agonist Compound 36 EC50 = 0.032 µM PMID: 18029176
CHEMBL250041 agonist Compound 48 EC50 = 0.046 µM PMID: 18029176
CHEMBL250042 agonist Compound 51 EC50 = 0.180 µM PMID: 18029176
CHEMBL250044 agonist Compound 56 EC50 = 2.34 µM PMID: 18029176
CHEMBL250887 agonist Compound 26 EC50 = 0.910 µM PMID: 18029176
CHEMBL250894 agonist Compound 40 EC50 = 0.158 µM PMID: 18029176
CHEMBL250896 agonist Compound 42 EC50 = 0.260 µM PMID: 18029176
CHEMBL251062 agonist Compound 28 EC50 = 0.419 µM PMID: 18029176
CHEMBL251063 agonist Compound 29 EC50 = 0.210 µM PMID: 18029176
CHEMBL251064 agonist Compound 57 EC50 = 0.386 µM PMID: 18029176
CHEMBL251065 agonist Compound 58 EC50 = 0.425 µM PMID: 18029176
CHEMBL251238 agonist Compound 18 EC50 = 7.54 µM PMID: 18029176
CHEMBL251239 agonist Compound 30 EC50 = 0.229 µM PMID: 18029176
CHEMBL251240 agonist Compound 31 EC50 = 0.252 µM PMID: 18029176
CHEMBL251419 agonist Compound 21 EC50 = 1.96 µM PMID: 18029176
CHEMBL251420 agonist Compound 22 EC50 = 2.67 µM PMID: 18029176
CHEMBL255388 agonist Compound 45 IC50 = 1.4 +/- 0.20 µM EC50 = 0.23 +/- 0.024 µM PMID: 18291645 PPAR_gamma
CHEMBL255389 agonist Compound 35 IC50 = 0.08 µM EC50 = 0.04 µM PMID: 18291645 PPAR_gamma
CHEMBL255392 agonist Compound 11b EC50 = 100 +/- 12 nM PMID: 21530275
PPAR_beta
CHEMBL255426 agonist Compound 10l EC50 = 1400 nM PMID: 18162399
PPAR_beta
CHEMBL255593 agonist Compound 10a EC50 = 1700 n M PMID: 18162399
CHEMBL255593 agonist Compound 11a EC50 = 1700 +/- 200 nM PMID: 21530275 PPAR_beta
CHEMBL255872 agonist Compound 33b IC50 = 1.078 µM EC50 = 0.023 µM PMID: 18511276 PPAR_gamma
CHEMBL256142 agonist Compound 33d IC50 = 0.499 µM EC50 = 0.008 µM PMID: 18511276 PPAR_gamma
CHEMBL256358 agonist Compound 33a IC50 = 0.861 µM EC50 = 0.01 µM PMID: 18511276 PPAR_gamma
CHEMBL256468 agonist Compound 37 IC50 = 0.79 +/- 0.037 µM EC50 = 0.01 +/- 0.001 µM PMID: 18291645 PPAR_gamma
CHEMBL257164 agonist Compound 22a IC50 = 0.711 µM EC50 = 0.044 µM PMID: 18511276 PPAR_gamma
CHEMBL257165 agonist Compound 25a IC50 = 0.215 µM EC50 = 0.005 µM PMID: 18511276 PPAR_gamma
CHEMBL257517 agonist Compound 41 IC50 = 0.46 +/- 0.04 µM EC50 = 0.008 +/- 0.0 µM PMID: 18291645 PPAR_gamma
CHEMBL258212 agonist Compound 24a IC50 = 1.37 µM EC50 = 0.018 µM PMID: 18511276 PPAR_gamma
CHEMBL258428 agonist Compound 21a IC50 = 7.62 µM EC50 = 0.209 µM PMID: 18511276
CHEMBL262558 agonist Compound 52 EC50 = 0.86 µM PMID: 12904063
CHEMBL262981 agonist Compound 2c EC50 = 790 nM PMID: 11527737 PPAR_gamma
CHEMBL270451 agonist Compound 10i EC50 = 140 nM PMID: 18162399
PPAR_beta
CHEMBL270587 agonist Compound 11g EC50 = 7.6 +/- 1.9 nM PMID: 21530275
PPAR_beta
CHEMBL270664 agonist Compound 10j EC50 = 28 nM PMID: 18162399
PPAR_beta
CHEMBL270665 agonist Compound 10h EC50 = 41 nM PMID: 18162399 PPAR_gamma
CHEMBL270801 agonist Compound 10e EC50 = 4 nM PMID: 18162399
PPAR_beta
CHEMBL271240 agonist Compound 17 IC50 = 0.36 +/- 0.005 µM EC50 = 0.07 +/- 0.005 µM PMID: 18291645 PPAR_gamma
CHEMBL271739 agonist Compound 44 IC50 = 2.4 +/- 0.22 µM EC50 = 0.11 +/- 0.008 µM PMID: 18291645 PPAR_gamma
CHEMBL271877 agonist Compound 10c EC50 = 37 nM PMID: 18162399
PPAR_beta
CHEMBL272336 agonist Compound 42 IC50 = 0.48 +/- 0.11 µM EC50 = 0.005 +/- 0.0002 µM PMID: 18291645 PPAR_gamma
CHEMBL272962 agonist Compound 46 IC50 = 1.3 +/- 0.2 µM EC50 = 0.09 +/- 0.008 µM PMID: 18291645 PPAR_gamma
CHEMBL280293 agonist Compound 13 IC50 = 2.64 µM EC50 = 2 µM PMID: 14505666 PPAR_gamma
CHEMBL305723 agonist Compound 2b EC50 = 500 nM PMID: 11527737
PPAR_beta
CHEMBL305854 agonist Compound 2d EC50 = 400 nM PMID: 11527737 PPAR_gamma
CHEMBL307728 agonist Compound 1n EC50 = 4 nM PMID: 11527737
PPAR_beta
CHEMBL309778 agonist Compound 1m EC50 = 40 nM PMID: 11527737
PPAR_beta
CHEMBL310426 agonist Compound 1f EC50 = 25 nM PMID: 11527737
PPAR_beta
CHEMBL310962 agonist Compound 1h EC50 = 40 nM PMID: 11527737
PPAR_beta
CHEMBL311429 agonist Compound 1a EC50 = 160 nM PMID: 11527737
PPAR_beta
CHEMBL312791 agonist Compound 1i EC50 = 32 nM PMID: 11527737
PPAR_beta
CHEMBL324449 agonist Compound 8 IC50 = 1.9 µM EC50 = 0.1 µM PMID: 15163205 PPAR_gamma
CHEMBL325723 agonist Compound 27 EC50 = 1.6 µM PMID: 12904063
PPAR_beta
CHEMBL326273 agonist Compound 7 IC50 = 1.5 µM EC50 = 3.0 µM PMID: 15163205 PPAR_gamma
CHEMBL326777 agonist Compound 69 EC50 = 9.4 µM PMID: 12904063
CHEMBL331206 agonist Compound 13 EC50 = 1.0 µM PMID: 12904063 PPAR_gamma
CHEMBL331464 agonist Compound 67 EC50 = 1.8 µM PMID: 12904063
CHEMBL331469 agonist Compound 51 EC50 = 0.32 µM PMID: 12904063 PPAR_gamma
CHEMBL331557 agonist Compound 23 EC50 = 2.9 µM PMID: 12904063
CHEMBL33188 agonist Compound 16 EC50 = 0.044 µM PMID: 15177462
PPAR_beta
CHEMBL332465 agonist Compound 11 EC50 = 0.36 µM PMID: 12904063 PPAR_beta
CHEMBL333778 agonist Compound 24 EC50 = 2.8 µM PMID: 12904063
CHEMBL343210 agonist Compound 15 PKi = 6.75 +/- 0.06 PEC50 = 5.74 +/- 0.09 PMID: 9836621 PPAR_gamma
CHEMBL356382 agonist Compound 12 PKi = 6.97 +/- 0.06 PEC50 = 6.41 +/- 0.04 PMID: 9836621 PPAR_gamma
CHEMBL358379 agonist Compound 4 PKi = 6.90 +/- 0.03 PEC50 = 5.98 +/- 0.07 PMID: 9836621 PPAR_gamma
CHEMBL363780 agonist Compound 24 IC50 = 0.007 µM EC50 = 0.002 µM PMID: 16107159
CHEMBL364467 agonist Compound 28 IC50 = 0.051 µM EC50 = 0.10 µM PMID: 15974597
CHEMBL364748 agonist Compound 1 EC50 = 7.94 +/- 1.70 µM PMID: 18835719 PPAR_gamma
CHEMBL369930 agonist Compound 48 EC50 = 82 nM PMID: 16275080 PPAR_gamma
CHEMBL370186 agonist Compound 58 EC50 = 38 nM PMID: 16275080 PPAR_gamma
CHEMBL370407 agonist Compound 8 EC50 = 7260 nM PMID: 16275080 PPAR_gamma
CHEMBL370809 agonist Compound 10 EC50 = 308 nM PMID: 16275080 PPAR_gamma
CHEMBL371041 agonist Compound 69 EC50 = 104 nM PMID: 16275080 PPAR_gamma
CHEMBL371195 agonist Compound 29 IC50 = 0.16 µM EC50 = 0.25 µM PMID: 15974597
CHEMBL371760 agonist Compound 64 EC50 = 523 nM PMID: 16275080 PPAR_gamma
CHEMBL371764 agonist Compound 40 EC50= 53 nM PMID: 16275080 PPAR_gamma
CHEMBL373318 agonist Compound 14b EC50 = 1632 nM PMID: 16137885 PPAR_gamma
CHEMBL376165 agonist Compound 5h EC50 = 41 +/- 8 nM PMID: 17532641
PPAR_beta
CHEMBL380961 agonist Compound 59 EC50 = 1170 nM PMID: 16275080 PPAR_gamma
CHEMBL381477 agonist Compound 19 IC50 = 130 nM EC50 = 454 nM PMID: 16384704
CHEMBL381891 agonist Compound 37 EC50 = 718 nM PMID: 16275080 PPAR_gamma
CHEMBL382718 agonist Compound 68 EC50 = 451 nM PMID: 16275080 PPAR_gamma
CHEMBL382957 agonist Compound 47 EC50 = 119 nM PMID: 16275080 PPAR_gamma
CHEMBL382982 agonist Compound 67 EC50 = 3280 nM PMID: 16275080 PPAR_gamma
CHEMBL383011 agonist Compound 23 IC50 = 116 nM EC50 = 15 nM PMID: 16384704
CHEMBL383398 agonist Compound 55 EC50 = 92 nM PMID: 16275080 PPAR_gamma
CHEMBL383789 agonist Compound 53 EC50 = 336 nM PMID: 16275080 PPAR_gamma
CHEMBL387588 agonist Compound 11s EC50 = 1237 nM PMID: 17157019 PPAR_gamma
CHEMBL387914 agonist Compound 5g EC50 = 8.2 +/- 1.4 nM PMID: 17532641
PPAR_beta
CHEMBL388008 agonist Compound 11n EC50 = 11.7 nM PMID: 17157019 PPAR_gamma
CHEMBL388422 agonist Compound 11b EC50 = 12 nM PMID: 17157019 PPAR_gamma
CHEMBL388645 agonist Compound 11d EC50 = 2.2 nM PMID: 17157019 PPAR_gamma
CHEMBL389297 agonist Compound 11i EC50 = 10.6 nM PMID: 17157019 PPAR_gamma
CHEMBL389298 agonist Compound 11l EC50 = 19 nM PMID: 17157019 PPAR_gamma
CHEMBL389903 agonist Compound 5d EC50 = 520 +/- 120 nM PMID: 17532641
PPAR_beta
CHEMBL390116 agonist Compound 10d EC50 = 230 +/- 30 nM PMID: 17532641
PPAR_beta
CHEMBL391620 agonist Compound 44 EC50 = 0.002 µM PMID: 17553678
PPAR_beta
CHEMBL392810 agonist Compound 33 EC50 = 0.16 µM PMID: 17553678
PPAR_beta
CHEMBL392811 agonist Compound 39 EC50 = 0.12 µM PMID: 17553678
CHEMBL393005 agonist Compound 11 EC50 = 6.05 µM PMID: 17507225 PPAR_gamma
CHEMBL393381 agonist Compound (R)-9d EC50 = 0.38 µM PMID: 17507225 PPAR_gamma
CHEMBL393593 agonist Compound 11 EC50 = 1150 nM PMID: 17157013
CHEMBL393777 agonist Compound 15 EC50 = 3090 nM PMID: 17157013
CHEMBL393778 agonist Compound 18 EC50 = 2120 nM PMID: 17157013
CHEMBL394031 agonist Compound (R)-9a EC50 = 0.26 µM PMID: 17507225 PPAR_gamma
CHEMBL396109 agonist Compound 10 EC50 = 1.51 µM PMID: 17507225 PPAR_gamma
CHEMBL398117 agonist Compound 27 EC50 = 0.003 µM PMID: 17553678
PPAR_beta
CHEMBL398118 agonist Compound 29 EC50 = 0.002 µM PMID: 17553678
PPAR_beta
CHEMBL398448 agonist Compound 19 EC50 = 6.39 µM PMID: 18029176
CHEMBL398684 agonist Compound 38 EC50 = 0.117 µM PMID: 18029176
CHEMBL398700 agonist Compound 43 EC50 = 0.160 µM PMID: 18029176
CHEMBL398722 agonist Compound 49 EC50 = 0.141 µM PMID: 18029176
CHEMBL398723 agonist Compound 50 EC50 = 0.166 µM PMID: 18029176
CHEMBL398737 agonist Compound 54 EC50 = 1.03 µM PMID: 18029176
CHEMBL398804 agonist Compound (S)-9d EC50 = 3.27 µM PMID: 17507225 PPAR_gamma
CHEMBL398936 agonist Compound 59 EC50 = 0.707 µM PMID: 18029176
CHEMBL399089 agonist Compound 41 EC50 = 0.195 µM PMID: 18029176
CHEMBL400093 agonist Compound 20 EC50 = 4.99 µM PMID: 18029176
CHEMBL400094 agonist Compound 25 EC50 = 1.11 µM PMID: 18029176
CHEMBL401015 agonist Compound 9b EC50 = 5.25 µM PMID: 17507225 PPAR_gamma
CHEMBL401116 agonist Compound 27 EC50 = 1.27 µM PMID: 18029176
CHEMBL401534 agonist Compound 33c IC50 = 0.654 µM EC50 = 0.016 µM PMID: 18511276 PPAR_gamma
CHEMBL402161 agonist Compound 4e EC50 = 53 +/- 5 nM PMID: 18662876
PPAR_beta
CHEMBL403847 agonist Compound 43 IC50 = 0.69 +/- 0.05 µM EC50 = 0.14 +/- 0.011 µM PMID: 18291645 PPAR_gamma
CHEMBL404646 agonist Compound 39 IC50 = 0.52 +/- 0.09 µM EC50 = 0.04 +/- 0.001 µM PMID: 18291645 PPAR_gamma
CHEMBL411118 agonist Compound 19 IC50 = 0.73 +/- 0.002 µM EC50 = 0.15 +/- 0.008 µM PMID: 18291645 PPAR_gamma
CHEMBL419019 agonist Compound 37 IC50 = 1.7 µM EC50 = 0.22 µM PMID: 15163205
CHEMBL419756 agonist Compound 15 IC50 = 2.1 µM EC50 = 0.12 µM PMID: 15163205 PPAR_gamma
CHEMBL425666 agonist Compound 5b EC50 = 12 +/- 3 nM PMID: 17532641
PPAR_beta
CHEMBL425725 agonist Compound 35 IC50 = 0.003 µM EC50 = 0.003 µM PMID: 16107159
CHEMBL425766 agonist Compound 10e IC50 = 0.470 µM EC50 = 0.050 µM PMID: 16451087
PPAR_beta
CHEMBL426483 agonist Compound  18 EC50 = 250 nM PMID: 16275077 PPAR_beta
CHEMBL427701 agonist Compound 41 EC50 = 0.001 µM PMID: 17553678
PPAR_beta
CHEMBL427710 agonist Compound 37 EC50 = 0.023 µM PMID: 18029176
CHEMBL428019 agonist Compound 9f EC50 = 3.94 µM PMID: 17507225 PPAR_gamma
CHEMBL428574 agonist Compound 32 EC50 = 0.005 µM PMID: 17553678
PPAR_beta
CHEMBL429734 agonist Compound 40 IC50 = 0.86 +/- 0.19 µM EC50 = 0.06 +/- 0.001 µM PMID: 18291645 PPAR_gamma
CHEMBL429824 agonist Compound 37 EC50 = 0.007 µM PMID: 17553678
PPAR_beta
CHEMBL433306 agonist Compound 1d EC50 = 40 nM PMID: 11527737
PPAR_beta
CHEMBL433316 agonist Compound 2g EC50 = 400 nM PMID: 11527737
PPAR_beta
CHEMBL434945 agonist Compound 1 EC50 = 1000 nM PMID: 16275080 PPAR_gamma
CHEMBL436113 agonist Compound 12 EC50 = 500 nM PMID: 16275080 PPAR_gamma
CHEMBL438979 agonist Compound 43 EC50 = 637 nM PMID: 16275080 PPAR_gamma
CHEMBL440758 agonist Compound 57 EC50 = 58 nM PMID: 16275080 PPAR_gamma
CHEMBL442909 agonist Compound 13 EC50 = 8.54 +/- 1.92 µM PMID: 18835719 PPAR_gamma
CHEMBL443910 agonist Compound 8h EC50 = 0.1 µM PMID: 18329751 PPAR_gamma
CHEMBL445942 agonist Compound 32b IC50 = 8.12 µM EC50 = 0.17 µM PMID: 18511276 PPAR_gamma
CHEMBL449099 agonist Compound 23 EC50 = 4.36 +/- 0.01 µM PMID: 18835719 PPAR_gamma
CHEMBL455853 agonist Compound 8a EC50 = 0.91 µM PMID: 18329751 PPAR_gamma
CHEMBL455957 agonist Compound 4c EC50 = 54 +/- 15 nM PMID: 18662876 PPAR_beta
CHEMBL456752 agonist Compound 4f EC50 = 60 +/- 4 nM PMID: 18662876
PPAR_beta
CHEMBL456753 agonist Compound 4g EC50 = 260 +/- 30 nM PMID: 18662876
PPAR_beta
CHEMBL456912 agonist Compound 7e EC50 = 0.001 µM PMID: 18329751 PPAR_gamma
CHEMBL456973 agonist Compound 4h EC50 = 13 +/- 4 nM PMID: 18662876
PPAR_beta
CHEMBL456974 agonist Compound 4i EC50 = 7.1 +/- 1.1 nM PMID: 18662876
PPAR_beta
CHEMBL457405 agonist Compound 4k EC50 = 7.5 +/- 1.5 nM PMID: 18662876
PPAR_beta
CHEMBL458221 agonist Compound 7d EC50 = 2.29 µM PMID: 18329751 PPAR_gamma
CHEMBL458648 agonist Compound 7b EC50 = 5.25 µM PMID: 18329751 PPAR_gamma
CHEMBL458866 agonist Compound 8b EC50 = 1.74 µm PMID: 18329751 PPAR_gamma
CHEMBL458867 agonist Compound 7c EC50 = 1.62 µM PMID: 18329751 PPAR_gamma
CHEMBL462982 agonist Compound 4d EC50 = 3.6 +/- 0.8 nM PMID: 18662876
PPAR_beta
CHEMBL469937 agonist Compound 24 EC50 = 1.39 +/- 0.26 µM PMID: 18835719 PPAR_gamma
CHEMBL470145 agonist Compound 26 EC50 = 3.06 +/- 0.99 µM PMID: 18835719 PPAR_gamma
CHEMBL471191 agonist Compound 21 EC50 = 3.16 +/- 0.21 µM PMID: 18835719 PPAR_gamma
CHEMBL471851 agonist Compound 17 EC50 = 4.03 +/- 2.50 µM PMID: 18835719 PPAR_gamma
CHEMBL473952 agonist Compound 2a IC50 = 0.07 µM EC50 = 0.011 µM PMID: 19201606 PPAR_gamma
CHEMBL473961 agonist Compound 1a IC50 = 5.92 µM EC50 = 1.47 µM PMID: 19201606 PPAR_gamma
CHEMBL474149 agonist Compound 2c IC50 = 0.14 µM EC50 = 0.311 µM PMID: 19201606 PPAR_gamma
CHEMBL474157 agonist Compound 1b IC50 = 0.09 µM EC50 = 0.12 µM PMID: 19201606 PPAR_gamma
CHEMBL474947 agonist Compound 4a IC50 = 2.77 µM EC50 = 6.15 µM PMID: 19201606 PPAR_gamma
CHEMBL475916 agonist Compound 5c EC50 = 3.24 µM PMID: 18771917 PPAR_gamma
CHEMBL475988 agonist Compound 8f EC50 = 1.55 µM PMID: 18329751 PPAR_gamma
CHEMBL475989 agonist Compound 7g EC50 = 1.20 µM PMID: 18329751 PPAR_gamma
CHEMBL476197 agonist Compound 8g EC50 = 0.17 µM PMID: 18329751 PPAR_gamma
CHEMBL477644 agonist Compound 8i EC50 = 0.72 µM PMID: 18329751 PPAR_gamma
CHEMBL477801 agonist Compound 5g EC50 = 3.12 µM PMID: 18771917 PPAR_gamma
CHEMBL478675 agonist Compound 5a EC50 = 5.98 µM PMID: 18771917 PPAR_gamma
CHEMBL482740 agonist Compound Rac-2Ea IC50 = 0.120 µM EC50 = 0.249 µM PMID: 19349176 PPAR_gamma
CHEMBL482827 agonist Compound 64 EC50 = 2.76 µM PMID: 18826205 PPAR_gamma
CHEMBL483032 agonist Compound 61 EC50 = 24.4 µM PMID: 18826205 PPAR_gamma
CHEMBL483035 agonist Compound 66 EC50 = 37.4 µM PMID: 18826205 PPAR_gamma
CHEMBL483341 agonist Compound Rac-2Da IC50 = 0.239 µM EC50 = 0.048 µM PMID: 19349176 PPAR_gamma
CHEMBL483351 agonist Compound Rac-3Ah IC50 = 0.432 µM EC50 = 0.123 µM PMID: 19349176 PPAR_gamma
CHEMBL484462 agonist Compound 63 EC50 = 4.39 µM PMID: 18826205 PPAR_gamma
CHEMBL485291 agonist Compound 68 EC50 = 3.95 µM PMID: 18826205 PPAR_gamma
CHEMBL486357 agonist Compound 11 EC50 = 2.23 +/- 0.52 µM PMID: 18835719 PPAR_gamma
CHEMBL486363 agonist Compound 10 EC50 = 2.55 +/- 0.07 µM PMID: 18835719 PPAR_gamma
CHEMBL486364 agonist Compound 12 EC50 = 2.48 /- 0.22 µM PMID: 18835719 PPAR_gamma
CHEMBL486365 agonist Compound 14 EC50 = 3.68 +/- 0.88 µM PMID: 18835719 PPAR_gamma
CHEMBL489171 agonist Compound 5n EC50 = 2.08 µM PMID: 18771917 PPAR_gamma
CHEMBL489172 agonist Compound 5p EC50 = 1.12 µM PMID: 18771917 PPAR_gamma
CHEMBL489363 agonist Compound 5i EC50 = 2.23 µM PMID: 18771917 PPAR_gamma
CHEMBL489364 agonist Compound 5j EC50 = 11.3 µM PMID: 18771917 PPAR_gamma
CHEMBL489377 agonist Compound 5s EC50 = 2.99 µM PMID: 18771917 PPAR_gamma
CHEMBL489563 agonist Compound 5k EC50 = 17.3 µm PMID: 18771917 PPAR_gamma
CHEMBL489591 agonist Compound 5y EC50 = 9.79 µM PMID: 18771917 PPAR_gamma
CHEMBL489768 agonist Compound 13c EC50 = 0.868 µM PMID: 18771917 PPAR_gamma
CHEMBL489769 agonist Compound 13d EC50 = 0.331 µM PMID: 18771917 PPAR_gamma
CHEMBL490395 agonist Compound 5m EC50 = 7.58 µM PMID: 18771917 PPAR_gamma
CHEMBL490401 agonist Compound 5q EC50 = 1.12 µM PMID: 18771917 PPAR_gamma
CHEMBL491423 agonist Compound 5u EC50 = 8.58 µM PMID: 18771917 PPAR_gamma
CHEMBL491596 agonist Compound 13a EC50 = 3.86 µM PMID: 18771917 PPAR_gamma
CHEMBL491597 agonist Compound 13b EC50 = 25.48 µM PMID: 18771917 PPAR_gamma
CHEMBL491606 agonist Compound 5l EC50 = 18.1 µM PMID: 18771917 PPAR_gamma
CHEMBL491622 agonist Compound 5v EC50 = 3.67 µM PMID: 18771917 PPAR_gamma
CHEMBL491623 agonist Compound 5x EC50 = 9.80 µM PMID: 18771917 PPAR_gamma
CHEMBL492031 agonist Compound 5t EC50 = 10.2 µM PMID: 18771917 PPAR_gamma
CHEMBL508225 agonist Compound 22 EC50 = 2.07 +/- 0.47 µM PMID: 18835719 PPAR_gamma
CHEMBL514007 agonist Compound 2d IC50 = 2.17 µM EC50 = 0.126 µM PMID: 19201606 PPAR_gamma
CHEMBL514256 agonist Compound 4j EC50 = 17 +/- 2 nM PMID: 18662876
PPAR_beta
CHEMBL514328 agonist Compound 1d IC50 = 0.89 µM EC50 = 0.66 µM PMID: 19201606 PPAR_gamma
CHEMBL514381 agonist Compound 7i EC50 = 1.29 µM PMID: 18329751 PPAR_gamma
CHEMBL514441 agonist Compound 8c EC50 = 1.20 µM PMID: 18329751 PPAR_gamma
CHEMBL514544 agonist Compound 5h EC50 = 0.542 µM PMID: 18771917 PPAR_gamma
CHEMBL514568 agonist Compound 8d EC50 = 0.10 µM PMID: 18329751 PPAR_gamma
CHEMBL514713 agonist Compound 7h EC50 = 0.07 µM PMID: 18329751 PPAR_gamma
CHEMBL514871 agonist Compound 5d EC50 = 7.72 µM PMID: 18771917 PPAR_gamma
CHEMBL515106 agonist Compound 3a IC50 = 0.069 µM EC50 = 1.90 µM PMID: 19201606 PPAR_gamma
CHEMBL515666 agonist Compound 8e EC50 = 0.91 µM PMID: 18329751 PPAR_gamma
CHEMBL515991 agonist Compound 7a EC50 = 1.23 µM PMID: 18329751 PPAR_gamma
CHEMBL516274 agonist Compound 5f EC50 = 3.40 µM PMID: 18771917 PPAR_gamma
CHEMBL519802 agonist Compound Rac-2Ag IC50 = 0.294 µM EC50 = 0.435 µM PMID: 19349176 PPAR_gamma
CHEMBL519857 agonist Compound 67 EC50 = 11.3 µM PMID: 18826205 PPAR_gamma
CHEMBL519974 agonist Compound Rac-3Ca IC50 = 0.069 µM EC50 = 0.087 µM PMID: 19349176 PPAR_gamma
CHEMBL521925 agonist Compound 60 EC50 = 3.99 µM PMID: 18826205 PPAR_gamma
CHEMBL522754 agonist Compound 5o EC50 = 0.064 µM PMID: 18771917 PPAR_gamma
CHEMBL523649 agonist Compound 5w EC50 = 7.67 µM PMID: 18771917 PPAR_gamma
CHEMBL523650 agonist Compound 62 EC50 = 6.78 µM PMID: 18826205 PPAR_gamma
CHEMBL523944 agonist Compound 5z EC50 = 1.70 µM PMID: 18771917 PPAR_gamma
CHEMBL549723 agonist Compound 7 EC50 = 0.25 +/- 0.05 µM PMID: 19556125 PPAR_gamma
CHEMBL550332 agonist Compound 14 EC50 = 0.049 +/- 0.02 µM PMID: 19556125 PPAR_gamma
CHEMBL551420 agonist Compound 20 EC50 = 0.22 +/- 0.04 µM PMID: 19556125 PPAR_gamma
CHEMBL551884 agonist Compound 18 EC50 = 0.39 +/- 0.02 µM PMID: 19556125 PPAR_gamma
CHEMBL552347 agonist Compound 6 EC50 = 0.29 +/- 0.04 µM PMID: 19556125 PPAR_gamma
CHEMBL557342 agonist Compound 9 EC50 = 0.085 +/- 0.03 µM PMID: 19556125 PPAR_gamma
CHEMBL558072 agonist Compound 12 EC50 = 0.19 +/- 0.04 µM PMID: 19556125 PPAR_gamma
CHEMBL558083 agonist Compound 12i IC50 = 87 nM EC50 = 107 nM PMID: 19530681 PPAR_gamma
CHEMBL560205 agonist Compound 13 EC50 = 0.55 +/- 0.03 µM PMID: 19556125 PPAR_gamma
CHEMBL560484 agonist Compound 8 EC50 = 0.09 +/- 0.02 µM PMID: 19556125 PPAR_gamma
CHEMBL561284 agonist Compound 15 EC50 = 2.0 +/- 0.43 µM PMID: 19556125 PPAR_gamma
CHEMBL561544 agonist Compound 10 EC50 = 0.021 +/- 0.01 µM PMID: 19556125 PPAR_gamma
CHEMBL563351 agonist Compound 19 EC50 = 0.11 +/- 0.01 µM PMID: 19556125 PPAR_gamma
CHEMBL563546 agonist Compound 16 EC50 = 0.15 +/- 0.02 µM PMID: 19556125 PPAR_gamma
CHEMBL564017 agonist Compound 17 EC50 = 0.025 +/- 0.02 µM PMID: 19556125 PPAR_gamma
CHEMBL564210 agonist Compound 12j IC50 = 764 nM EC50 = 129 nM PMID: 19530681 PPAR_gamma
CHEMBL572565 agonist Compound 5 EC50 = 0.107 +/- 0.006 µM PMID: 19775169 PPAR_gamma
CHEMBL572566 agonist Compound 6 EC50 = 0.60 +/- 0.13 µM PMID: 19775169 PPAR_gamma
CHEMBL573015 agonist Compound 8 EC50 = 0.31 +/- 0.16 µM PMID: 19775169 PPAR_gamma
CHEMBL573018 agonist Compound 12 EC50 = 1.75 +/- 0.12 µM PMID: 19775169 PPAR_gamma
CHEMBL573252 agonist Compound 7 EC50 = 0.488 +/- 0.017 µM PMID: 19775169 PPAR_gamma
CHEMBL574606 agonist Compound 14 EC50 = 1.36 +/- 0.06 µM PMID: 19775169 PPAR_gamma
CHEMBL574607 agonist Compound 15 EC50 = 0.72 +/- 0.20 µM PMID: 19775169 PPAR_gamma
CHEMBL574824 agonist Compound 10 EC50 = 1.4 +/- 0.4 µM PMID: 19775169 PPAR_gamma
CHEMBL578860 agonist Compound 3 EC50 = 0.060 +/- 0.006 µM PMID: 19775169 PPAR_gamma
CHEMBL583759 agonist Compound 9 EC50 = 3.6 +/- 1.5 µM PMID: 19775169 PPAR_gamma
CHEMBL602262 agonist Compound 7a IC50 = 7.04 µM EC50 = 4.96 µM PMID: 20079636 PPAR_gamma
CHEMBL76676 agonist Compound 1l EC50 = 40 nM PMID: 11527737
PPAR_beta
CHEMBL77040 agonist Compound 2a EC50 = 2000 nM PMID: 11527737 PPAR_gamma
CHEMBL78442 agonist Compound 2e EC50 = 320 nM PMID: 11527737
PPAR_beta
CHEMBL78476 agonist Compound 1o EC50 = 240 nM PMID: 11527737 PPAR_gamma
CHEMBL78523 agonist Compound 1c EC50 = 160 nM PMID: 11527737
PPAR_beta
CHEMBL78529 agonist Compound 12 IC50 = 473 +/- 41 nM EC50 = 75 +/- 22 nM PMID: 15115385 PPAR_gamma
CHEMBL80301 agonist Compound 1e EC50 = 79 nM PMID: 11527737
PPAR_beta
CHEMBL80364 agonist Compound 1k EC50 = 13 nM PMID: 11527737
PPAR_beta
CHEMBL80671 agonist Compound 1g EC50 = 13 nM PMID: 11527737
PPAR_beta
CHEMBL80772 agonist Compound 1b EC50 = 79 nM PMID: 11527737
PPAR_beta
CHEMBL80791 agonist Compound 2f EC50 = 200 nM PMID: 11527737
PPAR_beta
CHEMBL80905 agonist Compound 1j EC50 = 20 nM PMID: 11527737
PPAR_beta
CHEMBL80979 agonist Compound 2h EC50 = 50 nM PMID: 11527737 PPAR_gamma
CHEMBL81208 agonist Compound 11 IC50 = 1106 +/- 98 nM EC50 = 833 +/- 254 nM PMID: 15115385 PPAR_gamma
CHEMBL81592 agonist Compound 10 IC50 = 678 +/- 92 nM EC50 = 549 +/- 0 nM PMID: 15115385 PPAR_gamma
CHEMBL82193 agonist Compound 13 IC50 = 1846 +/- 109 nM EC50 = 2558 +/- 108 nM PMID: 15115385 PPAR_gamma
ZINC00001963 agonist pirinixic acid EC50 = 1.6 +/- 0.3 µM PMID: 19775169 PPAR_gamma
ZINC00001984 agonist fenofibric acid IC50 = 106 µM EC50 = 69 µM PMID: 19349176
ZINC00003515 agonist Compound 8 EC50 = 3.38 µM PMID: 12951082
ZINC00056648 agonist clofibrate EC50 = 55 µM PMID: 10691680
ZINC00590168 agonist Compound 9 EC50 = 0.24 µM PMID: 12904063 PPAR_gamma
ZINC00590170 agonist Compound 7 EC50 = 0.615 n M PMID: 12951082
ZINC00593304 agonist Compound 3 EC50 = 12.9 µM PMID: 21515063
PPAR_beta
ZINC00593306 agonist Compound 7 EC50 = 14.7 µM PMID: 21515063
PPAR_beta
ZINC00593307 agonist Compound 8 EC50 = 13.2 µM PMID: 21515063
PPAR_beta
ZINC00595076 agonist ly-518674 IC50 = 24 +/- 3 nM EC50 = 42 +/- 5 nM PMID: 14613314
ZINC00595446 agonist Compound 8 EC50 = 1.3 µM PMID: 12904063
ZINC00602989 agonist Compound 5-S IC50 = 0.74 nM EC50 = 0.06 µM PMID: 11814790 PPAR_gamma
ZINC00603089 agonist Compound 9 EC50 = 13.9 µM PMID: 21515063
PPAR_beta
ZINC01105900 agonist Compound 8 IC50 = 43 µM PMID: 18821746
ZINC01481822 agonist farglitazar pKi = 6.31 +/- 0.02 PEC50 = 6.34 +/- 0.10 PMID: 9836620 PPAR_gamma
ZINC01485982 agonist Compound (R)-2Ba IC50 = 2.370 µM EC50 = 1.91 µM PMID: 19349176 PPAR_gamma
ZINC01485983 agonist aleglitazar IC50 = 0.038 µM EC50 = 0.050 µM PMID: 19349176 PPAR_gamma
ZINC01487608 agonist Drf 2519 PMID: 15140637
ZINC01491415 agonist Compound 9a Ki = 28 µM EC50 = 12 µM PMID: 12443777 PPAR_gamma
ZINC01493488 agonist AD-5061 IC50 = 4086 +/- 363 nM EC50 = 771 +/- 44 nM PMID: 11405642
ZINC01494687 agonist Compound 6 IC50 = 1445 +/- 346 nM EC50 = 717 +/- 107 nM PMID: 11405642 PPAR_gamma
ZINC01536875 antagonist MK866 PMID: 11139388
ZINC01549535 agonist Compound 20 EC50 = 2.0 µM PMID: 12482434
PPAR_beta
ZINC01550501 agonist LY-465608 IC50 = 0.174µM EC50 = 0.15 µM PMID: 15293980 PPAR_gamma
ZINC01550769 agonist Tesaglitazar Ki = 1.0 µM EC50 = 1.7 µM PMID: 15293980 PPAR_gamma
ZINC01551431 agonist Compound 14i EC50 = 0.003 µM PMID: 17964792
ZINC01551432 agonist Ns-220 EC50 = 0.01 µM PMID: 17964792
ZINC01551433 agonist Compound 14g EC50 = 0.03 µM PMID: 17964792
ZINC01553275 agonist Compound 34 IC50 = 0.015 µM EC50 = 0.005 µM PMID: 15950464 PPAR_gamma
ZINC01553970 agonist Compound 19 EC50 = 1.1 µM PMID: 12482434
PPAR_beta
ZINC01553971 agonist Compound 18 EC50 = 0.3 µM PMID: 12482434
PPAR_beta
ZINC01554177 agonist Compound 5d Ki = 19 µM EC50 = 2.5 µM PMID: 12443777 PPAR_gamma
ZINC01554219 agonist Compound 9 Ki = 7.2 nM EC50 = 5 nM PMID: 12617924
PPAR_beta
ZINC01554220 agonist Compound 6 Ki = 7 nM EC50 = 8 nM PMID: 12617924
PPAR_beta
ZINC01554391 agonist Compound 7 IC50 = 54 nM EC50 = 18 nM PMID: 12657263
PPAR_beta
ZINC01902774 agonist Compound 3b Ki = 72 nM EC50 = 830 nM PMID: 11720854 PPAR_gamma
ZINC01910340 agonist Compound 3q EC50 = 0.36 +/- 0.16 µM PMID: 11831892 PPAR_gamma
ZINC01910883 agonist Compound 46 IC50 = 0.06 µM EC50 = 0.01 µM PMID: 15163205 PPAR_gamma
ZINC02541693 agonist L-165,041 EC50 = 977 nM PMID: 16797985
PPAR_beta
ZINC03817160 agonist TZD18 Ki = 0.03 µM EC50 = 0.03 µM PMID: 15293980 PPAR_gamma
ZINC03817161 agonist Compound 20 IC50 = 0.1 µM EC50 = 0.18 µM PMID: 12873517
ZINC03817162 agonist Compound 21 IC50 = 0.028 µM EC50 = 0.066 µM PMID: 12873517
ZINC03819472 agonist NNC 61-3058 EC50 = 0.5 µM PMID: 17379517
PPAR_beta
ZINC03819473 agonist Compound 6 EC50 = 0.067 +/- 0.030 µM PMID: 14584939
PPAR_beta
ZINC03832276 agonist farglitazar IC50 = 1217 nM EC50 = 345 nM PMID: 17005393 PPAR_gamma
ZINC03834054 agonist Compound 5 IC50 = 310 nM EC50 = 125 nM PMID: 12657263
LXR_alpha
ZINC03929313 agonist Krp-297 Ki = 0.2 µM EC50 = 1.0 µM PMID: 15293980 PPAR_gamma
ZINC03935839 agonist Compound 1 IC50 = 0.25 µM EC50 = 1.41 µM PMID: 18511276 PPAR_gamma
ZINC03940632 agonist Compound 4e Ki = 560 nM EC50 = 3600 nM PMID: 11720854
PPAR_beta
ZINC03942731 agonist Compound 24 IC50 = 253 nM EC50 = 0.09 µM PMID: 16737814 PPAR_gamma
ZINC03942732 agonist Compound 13 IC50 = 73 nM EC50 = 0.81 µM PMID: 16737814 PPAR_gamma
ZINC03942733 agonist Compound 14 IC50 = 181 nM EC50 = 1.0 µM PMID: 16737814 PPAR_gamma
ZINC03942734 agonist Compound 18 IC50 = 70 nM EC50 = 0.17 µM PMID: 16737814 PPAR_gamma
ZINC03942736 agonist Compound 25 IC50 = 149 nM EC50 = 0.05 µM PMID: 16737814 PPAR_gamma
ZINC03949307 agonist Compound (S)-(+)-35 EC50 = 0.165 µM PMID: 18029176
ZINC03950327 agonist Compound 1b IC50 = 2711 +/- 364 nM EC50 = 2816 +/- 35 nM PMID: 15582409 PPAR_gamma
ZINC03956919 agonist bezafibrate PMID: 11779144
ZINC03961821 agonist Compound 34v EC50 = 175 nM PMID: 17274610 PPAR_beta
ZINC03961823 agonist Compound 34ak EC50 = 180 nM PMID: 17274610 PPAR_beta
ZINC03961825 agonist Compound 34ad EC50 = 2480 nM PMID: 17274610 PPAR_beta
ZINC03961827 agonist Compound 34t EC50 = 526 nM PMID: 17274610 PPAR_beta
ZINC03964260 agonist Compound 4 IC50 = 0.23 µM EC50 = 0.30 µM PMID: 15801817 PPAR_gamma
ZINC03989107 agonist Compound 31 IC50 = 0.038 µM EC50 = 0.024 µM PMID: 15950464 PPAR_gamma
ZINC03989108 agonist Compound 29 IC50 = 0.037 µM EC50 = 0.006 µM PMID: 15950464 PPAR_gamma
ZINC03989109 agonist Compound 50 IC50 = 0.04 µM EC50 = 0.009 µM PMID: 15950464 PPAR_gamma
ZINC03990563 agonist Compound 14e EC50 = 0.24 µM PMID: 22197396 PPAR_gamma
ZINC03991715 agonist Compound 2 IC50 = 28 +/- 2 nM EC50 = 9 +/- 4 nM PMID: 15115385 PPAR_gamma
ZINC03992541 agonist Compound 48 IC50 = 0.063 µM EC50 = 0.04 µM PMID: 15163205 PPAR_gamma
ZINC03995991 agonist gw7647 EC50 = 0.006 µM PMID: 11354382 PPAR_gamma
ZINC04215181 agonist carbacyclin EC50 = 0.34 µM PMID: 11831892 PPAR_gamma
ZINC04474696 agonist eicosatetraenoic acid ED50 = 200 nM PMID: 8384714 PPAR_gamma
ZINC04546658 agonist 8S-HETE PMID: 7592593
ZINC04556656 agonist LTB4 PMID: 8900274
ZINC06069082 agonist reglitazar EC50 = 1.9 µM PMID: 15177462
ZINC08034993 agonist oleoylethanolamide EC50 = 110 nM PMID: 17228882
ZINC08387390 agonist Compound 5 IC50 = 1.5 µM PMID: 18821746
ZINC08730640 agonist Compound S-5 EC50 = 8.4 +/- 0.5 µM PMID: 16107150 PPAR_gamma
ZINC08730641 agonist Compound R-5 EC50 = 3.9 +/- 0.87 µM PMID: 16107150 PPAR_gamma
ZINC09260679 agonist Compound 7 IC50 = 1.0 µM PMID: 18821746
ZINC12358042 agonist Compound 5-R IC50 = 24 nM EC50 = 1.5 µM PMID: 11814790
ZINC12358141 agonist Compound 4 EC50 = 1.4 µM PMID: 10508427
PPAR_beta
ZINC12358142 agonist Compound 6 EC50 = 0.15 µM PMID: 10508427 PPAR_gamma
ZINC12358143 agonist Compound 5a Ki = 25 µM EC50 = 5 µM PMID: 12443777 PPAR_gamma
ZINC12358144 agonist Compound 5b Ki = 20 µM EC50 = 3.8 µM PMID: 12443777 PPAR_gamma
ZINC12358148 agonist Compound 9b Ki = 22 µM EC50 = 10 µM PMID: 12443777 PPAR_gamma
ZINC12358168 agonist Compound 4 IC50 = 10596 +/- 2044 nM EC50 = 2751 +/- 91 nM PMID: 11405642
ZINC12358170 agonist Compound 5 IC50 = 2033 +/- 440 nM EC50 = 625 +/- 125 nM PMID: 11405642 PPAR_gamma
ZINC12358171 agonist Compound 7 IC50 = 242 +/- 50 nM EC50 = 61.9 +/- 0.98 nM PMID: 11405642 PPAR_gamma
ZINC12358177 agonist Compound 3e EC50 = 12.4 +/- 4.3 µM PMID: 11831892
ZINC12358178 agonist Compound 3f EC50 = 9.0 +/- 3.3 µM PMID: 11831892
ZINC12358183 agonist Compound 3h EC50 = 9.6 +/- 3.0 µM PMID: 11831892
ZINC12358185 agonist Compound 3j EC50 = 11.7 +/- 4.2 µM PMID: 11831892
ZINC12358186 agonist Compound 3k EC50 = 1.2 +/- 0.58 µM PMID: 11831892
ZINC12358193 agonist Compound 3p EC50 = 0.14 +/- 0.054 µM PMID: 11831892 PPAR_gamma
ZINC12358195 agonist Compound 3r EC50 = 2.4 +/- 0.25 µM PMID: 11831892 PPAR_gamma
ZINC12358196 agonist Compound 3s EC50 = 0.22 +/- 0.099 µM PMID: 11831892 PPAR_gamma
ZINC12358209 agonist Compound 7 EC50 = 6.4 µM PMID: 12482434
PPAR_beta
ZINC12358210 agonist Compound 8 EC50 = 5.3 µM PMID: 12482434
PPAR_beta
ZINC12358211 agonist Compound 9 EC50 = 3.2 µM PMID: 12482434
PPAR_beta
ZINC12358212 agonist Compound 10 EC50 = 0.9 µM PMID: 12482434
PPAR_beta
ZINC12358213 agonist Compound 11 EC50 = 0.7 µM PMID: 12482434
PPAR_beta
ZINC12358214 agonist Compound 12 EC50 = 1.1 µM PMID: 12482434
PPAR_beta
ZINC12358215 agonist Compound 13 EC50 = 2.2 µM PMID: 12482434
PPAR_beta
ZINC12358216 agonist Compound 14 EC50 = 0.3 µM PMID: 12482434
PPAR_beta
ZINC12358217 agonist Compound 15 EC50 = 0.4 µM PMID: 12482434
PPAR_beta
ZINC12358218 agonist Compound 16 EC50 = 0.7 µM PMID: 12482434
PPAR_beta
ZINC12358219 agonist Compound 17 EC50 = 2.2 µM PMID: 12482434
PPAR_beta
ZINC12358236 agonist Compound 2 Ki = 14.0 nM EC50 = 3 nM PMID: 12617924
PPAR_beta
ZINC12358237 agonist Compound 4 Ki = 5.2 nM EC50 = 8 nM PMID: 12617924
PPAR_beta
ZINC12358238 agonist Compound 5 Ki = 3 nM EC50 = 3 nM PMID: 12617924
PPAR_beta
ZINC12358239 agonist Compound 7 Ki = 23 nM EC50 = 2 nM PMID: 12617924
PPAR_beta
ZINC12358240 agonist Compound 10 Ki = 46 nM EC50 = 50 nM PMID: 12617924
PPAR_beta
ZINC12358241 agonist Compound 14 Ki = 7.3 nM Transcript. max = 42 % PMID: 12617924
PPAR_beta
ZINC12358242 agonist Compound 15 Ki = 7.6 nM EC50 = 429 nM PMID: 12617924
PPAR_beta
ZINC12358243 agonist Compound 16 Ki = 213 nM EC50 = 53 nM PMID: 12617924
PPAR_beta
ZINC12358244 agonist Compound 17 Ki = 13 nM EC50 = 4 nM PMID: 12617924
PPAR_beta
ZINC12358245 agonist Compound 27 Ki = 50 nM Transcript. max = 56 % PMID: 12617924
PPAR_beta
ZINC12358246 agonist Compound 28 Ki = 18 nM EC50 = 13 nM PMID: 12617924
PPAR_beta
ZINC12358247 agonist Compound 18 Ki = 8.1 nM EC50 = 4 nM PMID: 12617924
PPAR_beta
ZINC12358248 agonist Compound 19 Ki = 9.3 nM EC50 = 2 nM PMID: 12617924
PPAR_beta
ZINC12358250 agonist Compound 20 Ki = 47 nM EC50 = 10 nM PMID: 12617924
PPAR_beta
ZINC12358252 agonist Compound 21 Ki = 17 nM EC50 = 2 nM PMID: 12617924
PPAR_beta
ZINC12358253 agonist Compound 24 Ki = 133 nM EC50 = 248 nM PMID: 12617924
PPAR_beta
ZINC12358254 agonist Compound 25 Ki = 255 nM EC50 = 92 nM PMID: 12617924
PPAR_beta
ZINC12358255 agonist Compound 29 Ki = 305 nM EC50 = 33 nM PMID: 12617924
PPAR_beta
ZINC12358256 agonist Compound 30 Ki = 121 nM EC50 = 3 nM PMID: 12617924
PPAR_beta
ZINC12358257 agonist Compound 1 IC50 = 7400 nM EC50 = 1600 nM PMID: 12657263
PPAR_beta
ZINC12358258 agonist Compound 2 IC50 = 600 nM EC50 = 260 nM PMID: 12657263
PPAR_beta
ZINC12358259 agonist Compound 3 IC50 = 100 nM EC50 = 74 nM PMID: 12657263
PPAR_beta
ZINC12358260 agonist Compound 4 IC50 = 570 nM EC50 = 247 nM PMID: 12657263
PPAR_beta
ZINC12358261 agonist Compound 6 IC50 = 1730 nM EC50 = 1300 nM PMID: 12657263
PPAR_beta
ZINC12358319 agonist Compound 9 EC50 = 2.72 µM PMID: 12951082
ZINC12358347 agonist Compound 14 IC50 = 19 +/- 2 nM EC50 = 31 +/- 6 nM PMID: 14613314
ZINC12358348 agonist Compound 15 IC50 = 16 +/- 2 nM EC50 = 6 +/- 1 nM PMID: 14613314
PPAR_beta
ZINC12358349 agonist Compound 16 IC50 = 220 +/- 19 nM EC50 = 220 +/- 15 nM PMID: 14613314
ZINC12358350 agonist Compound 17 IC50 = 250 +/- 52 nM EC50 = 56 +/- 7 nM PMID: 14613314
PPAR_beta
ZINC12358351 agonist Compound 18 IC50 = 15 +/- 1 nM EC50 = 2 +/- 0 nM PMID: 14613314
PPAR_beta
ZINC12358352 agonist Compound 19 IC50 = 12 +/- 1 nM EC50 = 4 +/- 1 nM PMID: 14613314
PPAR_beta
ZINC12358353 agonist Compound 20 IC50 = 27 +/- 2 nM EC50 = 88 +/- 26 nM PMID: 14613314
ZINC12358354 agonist Compound 21 IC50 = 960 +/- 48 nM EC50 = 2700 +/- 36 nM PMID: 14613314
ZINC12358496 agonist Compound 24 IC50 = 0.068 µM EC50 = 0.082 µM PMID: 12873517
ZINC12358498 agonist Compound 25 IC50 = 0.162 µM EC50 = 0.156 µM PMID: 12873517
ZINC12358499 agonist Compound 26 IC50 = 0.112 µM EC50 = 0.085 µM PMID: 12873517
ZINC12358523 agonist Compound 4 IC50 = 503 +/- 41 nM EC50 = 69 +/- 6 nM PMID: 15546740
ZINC12358524 agonist Compound 3 IC50 = 1546 +/- 36 nM EC50 = 390 +/- 23 nM PMID: 15546740 PPAR_gamma
ZINC12358525 agonist Compound 2 IC50 = 21 +/- 4 nM EC50 = 5 +/- 1 nM PMID: 15546740 PPAR_gamma
ZINC12358526 agonist ly-510929 ED50 = 0.004 mg/kg EC50 = 0.009 µM PMID: 15293980 PPAR_gamma
ZINC12358530 agonist Compound 5 IC50 = 167 +/- 25 nM EC50 = 7 +/- 1 nM PMID: 15546740
ZINC12358565 agonist Compound 2a IC50 = 1.4 µM EC50 = 4.02 µM PMID: 17292606 PPAR_gamma
ZINC12358567 agonist Compound 6 IC50 = 1.51 µM EC50 = 0.06 UM PMID: 15801817 PPAR_gamma
ZINC12358568 agonist Compound 7 IC50 = 1.03 µM EC50 = 0.62 µM PMID: 15801817
ZINC12358570 agonist Compound 8 IC50 = 0.10 µM EC50 = 0.75 µM PMID: 15801817
ZINC12358572 agonist Compound 9 IC50 = 0.48 µM EC50 = 0.01 µM PMID: 15801817 PPAR_gamma
ZINC12358582 agonist Compound 37 IC50 = 0.26 µM EC50 = 0.26 µM PMID: 15974597 PPAR_gamma
ZINC12358583 agonist Compound 38 IC50 = 0.064 µM EC50 = 0.076 µM PMID: 15974597 PPAR_gamma
ZINC12358584 agonist Compound 39 IC50 = 0.058 µM EC50 = 0.039 µM PMID: 15974597 PPAR_gamma
ZINC12358585 agonist Compound 40 IC50 = 0.023 µM EC50 = 0.056 µM PMID: 15974597 PPAR_gamma
ZINC12358586 agonist Compound 42 IC50 = 0.043 µM EC50 = 0.11 µM PMID: 15974597 PPAR_gamma
ZINC12358587 agonist Compound 43 IC50 = 0.089 µM EC50 = 0.25 µM PMID: 15974597 PPAR_gamma
ZINC12504466 agonist Compound 2 EC50 = 0.008 µM PMID: 17034149
PPAR_beta
ZINC13539257 agonist Compound 1 Ki = 63 nM PMID: 12951090 PPAR_gamma
ZINC13539263 agonist Compound 2 Ki = 28 nM PMID: 12951090 PPAR_gamma
ZINC13539269 agonist Compound 3 Ki = 57 nM PMID: 12951090 PPAR_gamma
ZINC13539277 agonist Compound 4 Ki = 225 nM PMID: 12951090
ZINC13539280 agonist Compound 5 Ki = 81 nM PMID: 12951090
ZINC13539289 agonist Compound 7 Ki = 293 nM PMID: 12951090 PPAR_gamma
ZINC13539294 agonist Compound 8 Ki = 61 nM PMID: 12951090 PPAR_gamma
ZINC13539300 agonist Compound 9 Ki = 38 nM PMID: 12951090
ZINC13539307 agonist Compound 10 (S) Ki = 12 nM PMID: 12951090 PPAR_gamma
ZINC13539310 agonist Compound 11 Ki = 98 nM PMID: 12951090
ZINC13539316 agonist Compound 14 Ki = 105 nM PMID: 12951090 PPAR_gamma
ZINC13539321 agonist Compound 15 Ki = 36 nM PMID: 12951090 PPAR_gamma
ZINC13539327 agonist Compound 16 Ki = 18 nM PMID: 12951090 PPAR_gamma
ZINC13539332 agonist Compound 18 Ki = 65 nM PMID: 12951090 PPAR_gamma
ZINC13671681 agonist Compound R-6 EC50 = 4.0 +/- 0.12 µM PMID: 16107150 PPAR_gamma
ZINC13671683 agonist Compound S-6 EC50 = 3.9 +/- 0.69 µM PMID: 16107150 PPAR_gamma
ZINC13671685 agonist Compound R-7 EC50 = 10.9 +/- 1.85 µM PMID: 16107150 PPAR_gamma
ZINC13671689 agonist Compound 8 EC50 = 0.5 +/- 0.12 µM PMID: 16107150 PPAR_gamma
ZINC13671691 agonist Compound 9 EC50 = 2.5 +/- 0.08 µM PMID: 16107150 PPAR_gamma
ZINC13671693 agonist Compound 10 EC50 = 13.5 +/- 2.19 µM PMID: 16107150 PPAR_gamma
ZINC13671695 agonist Compound 11 EC50 = 0.5 +/- 0.04 µM PMID: 16107150 PPAR_gamma
ZINC13671697 agonist Compound 12 EC50 = 0.7 +/- 0.06 µM PMID: 16107150 PPAR_gamma
ZINC13671698 agonist Compound 13 EC50 = 28.7 +/- 2.91 µM PMID: 16107150 PPAR_gamma
ZINC13671700 agonist Compound 14 EC50 = 0.9 +/- 0.14 µM PMID: 16107150 PPAR_gamma
ZINC13671702 agonist Compound 15 EC50 = 1.4 +/- 0.05 µM PMID: 16107150 PPAR_gamma
ZINC13671825 agonist Compound 27 IC50 = 0.006 µM EC50 = 0.002 µM PMID: 16107159
ZINC13671830 agonist Compound 29 IC50 = 0.003 µM EC50 = 0.002 µM PMID: 16107159
ZINC13671855 agonist Compound 37 IC50 = 0.004 µM EC50 = 0.002 µM PMID: 16107159
ZINC13671857 agonist Compound 39 IC50 = 0.162 µM EC50 = 0.041 µM PMID: 16107159
ZINC13671864 agonist Compound 41 IC50 = 0.264 µM EC50 = 0.057 µM PMID: 16107159
ZINC13973809 agonist Compound (S)-2Ba IC50 = 0.053 µM EC50 = 0.027 µM PMID: 19349176 PPAR_gamma
ZINC13973811 agonist Compound (R)-2Aa IC50 = 4.610 µM EC50 = 0.358 µM PMID: 19349176 PPAR_gamma
ZINC13973813 agonist Compound (R)-3Aa IC50 = 0.918 µM EC50 = 0.65 µM PMID: 19349176 PPAR_gamma
ZINC13974182 agonist Compound 17j IC50 = 0.034 µM EC50 = 0.061 µM PMID: 19783444 PPAR_gamma
ZINC13976592 agonist Compound 10 IC50 = 756 nM EC50 = 0.19 µM PMID: 16737814 PPAR_gamma
ZINC13981013 agonist Compound 43 IC50 = 0.11 µM EC50 = 0.04 µM PMID: 15950464 PPAR_gamma
ZINC13982030 agonist Compound 13 %inhibition = 44.5 PMID: 18083521
PPAR_beta
ZINC13983069 agonist Compound 7 EC50 = 0.01 µM PMID: 18947994 PPAR_gamma
ZINC13983071 agonist Compound 11 EC50 = 0.002 µM PMID: 18947994
PPAR_beta
ZINC13983073 agonist Compound 13 EC50 = 0.010 µM PMID: 18947994 PPAR_gamma
ZINC13983075 agonist Compound 9 EC50 = 0.004 µM PMID: 18947994
PPAR_beta
ZINC13983079 agonist Compound 27 EC50 = 0.004 µM PMID: 18947994
PPAR_beta
ZINC13983851 agonist Compound 3d SS EC50 = 62 nM PMID: 16275080 PPAR_gamma
ZINC14096589 agonist Compound 5 EC50 = 0.41 µM PMID: 10508427
PPAR_beta
ZINC14115100 agonist gw9578 IC50 = 120 +/- 11 nM EC50 = 340 +/- 130 nM PMID: 14613314
PPAR_beta
ZINC14209392 agonist Compound 9 (R) IC50 = 4257 +/- 235 nM EC50 = 877 +/- 174 nM PMID: 16970391
PPAR_beta
ZINC14209394 agonist Compound 14 IC50 = 3758 +/- 0 nM EC50 = 1524 +/- 346 nM PMID: 16970391
PPAR_beta
ZINC14262259 agonist Compound 7 EC50 = 0.79 µM PMID: 10508427 PPAR_gamma
ZINC14976995 agonist Compound 17b EC50 = 1980 nM PMID: 17274610 PPAR_beta
ZINC14976998 agonist Compound 17c EC50 = 1610 nM PMID: 17274610
ZINC14977001 agonist Compound 17d EC50 = 6800 nM PMID: 17274610 PPAR_beta
ZINC14977010 agonist Compound 17g EC50 = 5700 nM PMID: 17274610 PPAR_beta
ZINC14977022 agonist Compound 29f EC50 = 7280 nM PMID: 17274610 PPAR_beta
ZINC14977028 agonist Compound 17l EC50 = 9360 nM PMID: 17274610 PPAR_beta
ZINC14977034 agonist Compound 17n EC50 = 1140 nM PMID: 17274610 PPAR_beta
ZINC14977037 agonist Compound 17o EC50 = 3950 nM PMID: 17274610 PPAR_beta
ZINC14977051 agonist Compound 17r EC50 = 700 nM PMID: 17274610 PPAR_beta
ZINC14977054 agonist Compound 17s EC50 = 7500 nM PMID: 17274610 PPAR_beta
ZINC14977064 agonist Compound 17v EC50 = 9200 nM PMID: 17274610 PPAR_beta
ZINC14977067 agonist Compound 17w EC50 = 6850 nM PMID: 17274610 PPAR_beta
ZINC14977072 agonist Compound 17x EC50 = 520 nM PMID: 17274610 PPAR_beta
ZINC14977078 agonist Compound 29b EC50 = 3270 nM PMID: 17274610 PPAR_beta
ZINC14977081 agonist Compound 29c EC50 = 6600 nM PMID: 17274610 PPAR_beta
ZINC14977084 agonist Compound 29d EC50 = 1690 nM PMID: 17274610 PPAR_beta
ZINC14977098 agonist Compound 29h EC50 = 5260 nM PMID: 17274610 PPAR_beta
ZINC14977102 agonist Compound 29i EC50 = 2900 nM PMID: 17274610 PPAR_beta
ZINC14977105 agonist Compound 34a EC50 = 111 nM PMID: 17274610 PPAR_beta
ZINC14977108 agonist Compound 34b EC50 = 255 nM PMID: 17274610 PPAR_beta
ZINC14977111 agonist Compound 34c EC50 = 268 nM PMID: 17274610 PPAR_beta
ZINC14977118 agonist Compound 34e EC50 = 147 nM PMID: 17274610 PPAR_beta
ZINC14977121 agonist Compound 34f EC50 = 254 nM PMID: 17274610 PPAR_beta
ZINC14977124 agonist Compound 34g EC50 = 87 nM PMID: 17274610 PPAR_beta
ZINC14977127 agonist Compound 34h EC50 = 197 nM PMID: 17274610 PPAR_beta
ZINC14977130 agonist Compound 34i EC50 = 437 nM PMID: 17274610 PPAR_beta
ZINC14977135 agonist Compound 34j EC50 = 1250 nM PMID: 17274610 PPAR_beta
ZINC14977140 agonist Compound 34k EC50 = 83 nM PMID: 17274610 PPAR_beta
ZINC14977143 agonist Compound 34l EC50 = 112 nM PMID: 17274610 PPAR_beta
ZINC14977146 agonist Compound 34m EC50 = 328 nM PMID: 17274610 PPAR_beta
ZINC14977150 agonist Compound 34n EC50 = 53 nM PMID: 17274610 PPAR_beta
ZINC14977153 agonist Compound 34o EC50 = 391 nM PMID: 17274610 PPAR_beta
ZINC14977156 agonist Compound 34p EC50 = 43 nM PMID: 17274610 PPAR_beta
ZINC14977159 agonist Compound 34q EC50 = 44 nM PMID: 17274610 PPAR_beta
ZINC14977162 agonist Compound 34r EC50 = 101 nM PMID: 17274610 PPAR_beta
ZINC14977165 agonist Compound 34s EC50 = 328 nM PMID: 17274610 PPAR_beta
ZINC14977169 agonist Compound 34u EC50 = 2530 nM PMID: 17274610 PPAR_beta
ZINC14977174 agonist Compound 34w EC50 = 560 nM PMID: 17274610 PPAR_beta
ZINC14977178 agonist Compound 34x EC50 = 140 nM PMID: 17274610 PPAR_beta
ZINC14977181 agonist Compound 34y EC50 = 803 nM PMID: 17274610 PPAR_beta
ZINC14977184 agonist Compound 34aa EC50 = 1690 nM PMID: 17274610 PPAR_beta
ZINC14977190 agonist Compound 34ac EC50 = 6490 nM PMID: 17274610 PPAR_beta
ZINC14977193 agonist Compound 34ae EC50 = 5800 nM PMID: 17274610 PPAR_beta
ZINC14977197 agonist Compound 34af EC50 = 755 nM PMID: 17274610 PPAR_beta
ZINC14977200 agonist Compound 34ag EC50 = 100 nM PMID: 17274610 PPAR_beta
ZINC14977203 agonist Compound 34ah EC50 = 105 nM PMID: 17274610 PPAR_beta
ZINC14977206 agonist Compound 34ai EC50 = 1350 nM PMID: 17274610 PPAR_beta
ZINC14977209 agonist Compound 34aj EC50 = 47 nM PMID: 17274610 PPAR_beta
ZINC14977213 agonist Compound 34al EC50 = 61 nM PMID: 17274610 PPAR_beta
ZINC14977216 agonist Compound 34am EC50 = 150 nM PMID: 17274610 PPAR_beta
ZINC14977219 agonist Compound 34an EC50 = 520 nM PMID: 17274610 PPAR_beta
ZINC15634239 agonist gw409544 EC50 = 2.3 +/- 0.5 nM PMID: 11698662
ZINC16052147 agonist Compound 8 EC50 = 0.032 µM PMID: 17034149 PPAR_gamma
ZINC16052148 agonist Compound 10 EC50 = 0.282 µM PMID: 17034149
PPAR_beta
ZINC16052349 agonist gw735 EC50 = 0.004 +/- 0.002 µM PMID: 17243659 PPAR_beta
ZINC17654911 antagonist gw6471 IC50 = 0.24 µM PMID: 11845213
ZINC26743888 agonist Compound 19 EC50 = 710 nM PMID: 11677135
PPAR_beta
ZINC26744992 agonist Compound 20 EC50 = 620 nM PMID: 11677135
PPAR_beta
ZINC26747370 agonist Compound 21 EC50 = 230 nM PMID: 11677135
PPAR_beta
ZINC26747391 agonist Compound 18 EC50 = 230 nM PMID: 11677135
PPAR_beta
ZINC26749852 agonist Compound 22 EC50 = 59 nM PMID: 11677135
PPAR_beta
ZINC26949801 agonist Compound 17 Ki = 64 nM PMID: 12951090 PPAR_gamma
ZINC27101582 agonist Compound 14 EC50 = 0.07 µM PMID: 15177462
PPAR_beta
ZINC27102276 agonist Compound 18 EC50 = 0.17 µM PMID: 15177462
PPAR_beta
ZINC27103304 agonist Compound 10 EC50 = 0.03 µM PMID: 15177462
PPAR_beta
ZINC28109335 agonist Compound 28 IC50 = 0.09 µM EC50 = 0.036 µM PMID: 15950464 PPAR_gamma
ZINC28109342 agonist Compound 27 IC50 = 0.40 µM EC50 = 0.13 µM PMID: 15950464 PPAR_gamma
ZINC28111541 agonist Compound 48 IC50 = 0.23 µM EC50 = 0.08 µM PMID: 15950464
ZINC28116577 agonist Compound 35 IC50 = 0.61 µM EC50 = 0.3 µM PMID: 15950464 PPAR_gamma
ZINC28118861 agonist Compound 33 IC50 = 0.18 µM EC50 = 0.028 µM PMID: 15950464 PPAR_gamma
ZINC28120531 agonist Compound 51 IC50 = 0.028 µM EC50 = 0.002 µM PMID: 15950464 PPAR_gamma
ZINC28121066 agonist Compound 32 IC50 = 0.029 µM EC50 = 0.007 µM PMID: 15950464 PPAR_gamma
ZINC28122017 agonist Compound 45 IC50 = 0.39 µM EC50 = 0.14 µM PMID: 15950464 PPAR_gamma
ZINC28122027 agonist Compound 47 IC50 = 0.016 µM EC50 = 0.006 µM PMID: 15950464 PPAR_gamma
ZINC28122238 agonist Compound 40 IC50 = 0.057 µM EC50 = 0.02 µM PMID: 15950464
ZINC28123579 agonist Compound 8a EC50 = 0.71 +/- 0.32 µM PMID: 14584939
PPAR_beta
ZINC28123586 agonist Compound 3 EC50 = 3.7 µm PMID: 15713415 PPAR_beta
ZINC28124323 agonist Compound 41 IC50 = 1.38 µM EC50 = 0.22 µM PMID: 15950464
ZINC28124485 agonist Compound 42 IC50 = 0.24 µM EC50 = 0.04 µM PMID: 15950464
ZINC28124682 agonist Compound 36 IC50 = 1.7 µM EC50 = 0.7 µM PMID: 15950464 PPAR_gamma
ZINC28124966 agonist Compound 37 IC50 = 0.71 µM EC50 = 0.022 µM PMID: 15950464
ZINC28125812 agonist Compound 7 EC50 = 6.69 +/- 2.19 µM PMID: 14584939
PPAR_beta
ZINC28125854 agonist Compound 46 IC50 = 0.048 µM EC50 = 0.023 µM PMID: 15950464 PPAR_gamma
ZINC28126012 agonist Compound 52 IC50 = 1.6 µM EC50 = 0.42 µM PMID: 15950464 PPAR_gamma
ZINC28126020 agonist Compound 49 IC50 = 0.007 µM EC50 = 0.004 µM PMID: 15950464
ZINC28126083 agonist Compound 44 IC50 = 0.6 µM EC50 = 0.24 µM PMID: 15950464
ZINC28126520 agonist Compound 30 IC50 = 0.066 µM EC50 = 0.004 µM PMID: 15950464 PPAR_gamma
ZINC28127637 agonist Compound 1 EC50 = 1.6 µM PMID: 17379517
PPAR_beta
ZINC28130594 agonist Compound 9 EC50 = 1.1 µM PMID: 15713415 PPAR_beta
ZINC28131151 agonist Compound 6 EC50 = 1.2 µM PMID: 15713415 PPAR_beta
ZINC28131157 agonist Compound 7 EC50 = 1.8 µM PMID: 15713415 PPAR_beta
ZINC28133768 agonist Compound 53 IC50 = 1.7 µM EC50 = 1 µM PMID: 15950464 PPAR_gamma
ZINC28134719 agonist Compound 11 EC50 = 15 µM PMID: 15713415
ZINC28137414 agonist Compound 54 IC50 = 0.14 µM EC50 = 0.061 µM PMID: 15950464 PPAR_gamma
ZINC28227882 agonist Compound 36 EC50 = 9.3 +/- 0.9 µM PMID: 21889235
ZINC28232464 agonist Compound 6k EC50 = 0.009 µM PMID: 11354382
ZINC28232511 agonist Compound 6b EC50 = 0.017 µM PMID: 11354382 PPAR_beta
ZINC28233930 agonist Compound 6e EC50 = 0.10 µM PMID: 11354382
ZINC28235468 agonist Compound 6a EC50 = 0.005 µM PMID: 11354382 PPAR_beta
ZINC28235832 agonist Compound 6c EC50 = 0.008 µM PMID: 11354382 PPAR_beta
ZINC28235931 agonist Compound 6j EC50 = 0.02 µM PMID: 11354382
ZINC28236053 agonist Compound 6h EC50 = 0.006 µM PMID: 11354382 PPAR_beta
ZINC28236058 agonist Compound 6g EC50 = 0.05 µM PMID: 11354382
ZINC28237151 agonist Compound 6d EC50 = 0.009 µM PMID: 11354382
ZINC28238554 agonist Compound 6i EC50 = 0.001 µM PMID: 11354382
ZINC28330592 agonist Compound 4 EC50 = 9.6 µM PMID: 15713415
ZINC28339538 agonist Compound 1e IC50 = 1349 +/- 357 nM EC50 = 2152 +/- 87 nM PMID: 15582409 PPAR_gamma
ZINC28345549 agonist Compound 1d IC50 = 1686 +/- 168 nM EC50 = 2754 +/- 76 nM PMID: 15582409 PPAR_gamma
ZINC28358143 agonist Compound 1h IC50 = 770 +/- 156 nM EC50 = 2622 +/- 94 nM PMID: 15582409 PPAR_gamma
ZINC28362956 agonist Compound 1f IC50 = 309 +/- 38 nM EC50 = 2713 +/- 30 nM PMID: 15582409 PPAR_gamma
ZINC28366730 agonist Compound 1g IC50 = 1154 +/- 182 nM EC50 = 1880 +/- 86 nM PMID: 15582409 PPAR_gamma
ZINC28369948 agonist Compound 1c IC50 = 470 +/- 20 nM EC50 = 2870 +/- 32 nM PMID: 15582409 PPAR_gamma
ZINC28455668 agonist Compound 9 IC50 = 149 +/- 28 nM EC50 = 11 +/- 2 nM PMID: 15546740
ZINC28455675 agonist Compound 10 IC50 = 196 +/- 21 nM EC50 = 260 +/- 28 nM PMID: 15546740
ZINC28456444 agonist Compound 11 IC50 = 133 +/- 12 nM EC50 = 49 +/- 5 nM PMID: 15546740
ZINC28456862 agonist Compound 6 IC50 = 64 +/- 8 nM EC50 = 7 +/- 1 nM PMID: 15546740
ZINC28458016 agonist Compound 7 IC50 = 375 +/- 26 nM EC50 = 39 +/- 3 nM PMID: 15546740
ZINC28458271 agonist Compound 8 IC50 = 306 +/- 52 nM EC50 = 23 +/- 5 nM PMID: 15546740
ZINC28563114 agonist Compound 4 EC50 = 670 nM PMID: 17601734
ZINC28563304 agonist Compound 45a SR EC50 = 48 nM PMID: 16275080 PPAR_gamma
ZINC28563388 agonist Compound 2 EC50 = 220 nM PMID: 17601734
ZINC28563441 agonist Compound 45d SS EC50 = 78 nM PMID: 16275080 PPAR_gamma
ZINC28563449 agonist Compound 54c RR EC50 = 868 nM PMID: 16275080
ZINC28563467 agonist Compound 54c SS EC50 = 94 nM PMID: 16275080 PPAR_gamma
ZINC28563544 agonist Compound 3 EC50 = 130 nM PMID: 17601734 PPAR_gamma
ZINC28563558 agonist Compound 45b RS EC50 = 1520 nM PMID: 16275080
ZINC28563574 agonist Compound 66d SS EC50 = 57 nM PMID: 16275080 PPAR_gamma
ZINC28563719 agonist Compound 66c RR EC50 = 63 nM PMID: 16275080 PPAR_gamma
ZINC28563761 agonist Compound 3b RS EC50 = 350 nM PMID: 16275080 PPAR_gamma
ZINC28564009 agonist Compound 3a SR EC50 = 26 nM PMID: 16275080 PPAR_gamma
ZINC28569243 agonist Compound 16a EC50 = 10 nM PMID: 16275077
PPAR_beta
ZINC28569401 agonist Compound 16b EC50 = 12 nM PMID: 16275077
PPAR_beta
ZINC28569402 agonist Compound 19 EC50 = 180 nM PMID: 16275077 PPAR_beta
ZINC28570405 agonist Compound 1a IC50 = 568 +/- 50 nM EC50 = 1100 +/- 147 nM PMID: 15582409 PPAR_gamma
ZINC28571180 agonist Compound 11 IC50 = 30 nM EC50 = 20 nM PMID: 16384704
ZINC28571310 agonist Compound 35 IC50 = 28 nM EC50 = 44 nM PMID: 16384704
ZINC28571328 agonist Compound 33 IC50 = 22 nM EC50 = 27.5 nM PMID: 16384704
ZINC28571381 agonist Compound 39 IC50 = 20 nM EC50 = 7.3 nM PMID: 16384704
ZINC28571390 agonist Compound 22 IC50 = 22 nM EC50 = 2.7 nM PMID: 16384704
ZINC28571656 agonist Compound 37 IC50 = 49 nM EC50 = 10 nM PMID: 16384704
ZINC28571728 agonist Compound 24 IC50 = 6 nM EC50 = 3 nM PMID: 16384704
ZINC28571729 agonist Compound 25 IC50 = 101 nM EC50 = 20 nM PMID: 16384704
ZINC28571738 agonist Compound 26 IC50 = 42 nM EC50 = 54.1 nM PMID: 16384704
ZINC28571971 agonist Compound 27 IC50 = 3 nM EC50 = 2.1 nM PMID: 16384704
ZINC28572206 agonist Compound 29 IC50 = 30 nM EC50 = 11.4 nM PMID: 16384704
ZINC28572207 agonist Compound 30 IC50 = 3 nM EC50 = 2.9 nM PMID: 16384704
ZINC28604428 agonist Compound 23 EC50 = 0.07 +/- 0.01 µM PMID: 17243659 PPAR_beta
ZINC28604539 agonist Compound 9 Ki = 2.0 µM EC50 = 1.23 µM PMID: 16979341
ZINC28652283 agonist Compound (R)-5 EC50 = 620 +/- 60.0 nM PMID: 21128600 PPAR_beta
ZINC28652287 agonist Compound (S)-5 EC50 = 250 +/- 60.0 nM PMID: 21128600 PPAR_beta
ZINC28710190 agonist Compound 21 EC50 = 468 nM PMID: 18155554 PPAR_beta
ZINC28710191 agonist Compound 22 EC50 = 79 nM PMID: 18155554
PPAR_beta
ZINC28710192 agonist Compound 23 EC50 = 33 nM PMID: 18155554 PPAR_beta
ZINC28710193 agonist Compound 24 EC50 = 186 nM PMID: 18155554 PPAR_beta
ZINC28710197 agonist Compound 76 EC50 = 94 nM PMID: 18155554 PPAR_beta
ZINC28710198 agonist Compound 77 EC50 = 94 nM PMID: 18155554 PPAR_beta
ZINC28710199 agonist Compound 87 EC50 = 736 nM PMID: 18155554
ZINC28821850 agonist Compound 56 EC50 = 425 nM PMID: 18155554 PPAR_beta
ZINC28821851 agonist Compound 57 EC50 = 656 nM PMID: 18155554 PPAR_beta
ZINC28825459 agonist Compound 5 IC50 = 3487 nM EC50 = 1253 nM PMID: 18029178
PPAR_beta
ZINC28825460 agonist Compound 6 IC50 = 1763 nM EC50 = 921 nM PMID: 18029178
PPAR_beta
ZINC28825461 agonist Compound 7 IC50 = 1127 nM EC50 = 828 nM PMID: 18029178
PPAR_beta
ZINC28825462 agonist Compound 8 IC50 = 1230 nM EC50 = 836 nM PMID: 18029178
PPAR_beta
ZINC28825463 agonist Compound 9 IC50 = 640 nM EC50 = 466 nM PMID: 18029178
PPAR_beta
ZINC28825464 agonist Compound 10 IC50 = 1594 nM EC50 = 590 nM PMID: 18029178
PPAR_beta
ZINC28825466 agonist Compound 12 IC50 = 1483 nM EC50 = 706 nM PMID: 18029178
PPAR_beta
ZINC28825467 agonist Compound 13 IC50 = 163 nM EC50 = 329 nM PMID: 18029178
PPAR_beta
ZINC28825468 agonist Compound 14 IC50 = 1749 nM EC50 = 1042 nM PMID: 18029178
PPAR_beta
ZINC28825469 agonist Compound 15 IC50 = 7154 nM EC50 = 2205 nM PMID: 18029178
PPAR_beta
ZINC28825470 agonist Compound 16 IC50 = 4850 nM EC50 = 420 nM PMID: 18029178
PPAR_beta
ZINC28825471 agonist Compound 17 IC50 = 4200 nM EC50 = 1504 nM PMID: 18029178
PPAR_beta
ZINC28825473 agonist Compound 19 IC50 = 188 nM EC50 = 792 nM PMID: 18029178
PPAR_beta
ZINC28825474 agonist Compound 20 IC50 = 313 nM EC50 = 544 nM PMID: 18029178
PPAR_beta
ZINC28825475 agonist Compound 21 IC50 = 331 nM EC50 = 877 nM PMID: 18029178
PPAR_beta
ZINC28825476 agonist Compound 22 IC50 = 728 nM EC50 = 754 nM PMID: 18029178
PPAR_beta
ZINC28825477 agonist Compound 23 IC50 = 384 nM EC50 = 1053 nM PMID: 18029178
PPAR_beta
ZINC28890871 agonist Compound 9 IC50 = 9110 nM EC50 = 2690 nM PMID: 17129725
PPAR_beta
ZINC28890877 agonist Compound 10 IC50 = 4500 nM EC50 = 2800 nM PMID: 17129725
PPAR_beta
ZINC28890881 agonist Compound 11 IC50 = 8290 nM EC50 = 1870 nM PMID: 17129725
PPAR_beta
ZINC28890901 agonist Compound 14 IC50 = 4100 nM EC50 = 2680 nM PMID: 17129725
PPAR_beta
ZINC28890927 agonist Compound 16 IC50 = 4990 nM EC50 = 2810 nM PMID: 17129725
PPAR_beta
ZINC28890943 agonist Compound 19 IC50 = 5880 nM EC50 = 2340 nM PMID: 17129725
PPAR_beta
ZINC28890948 agonist Compound 20 IC50 = 7350 nM EC50 = 2850 nM PMID: 17129725
PPAR_beta
ZINC28890954 agonist Compound 21 IC50 = 6090 nM EC50 = 2630 nM PMID: 17129725
PPAR_beta
ZINC28900597 agonist Compound 18 EC50 = 0.63 µM PMID: 17553678 PPAR_gamma
ZINC28900602 agonist Compound 19 EC50 = 0.03 µM PMID: 17553678 PPAR_gamma
ZINC28900607 agonist Compound 20 EC50 = 0.1 µM PMID: 17553678
PPAR_beta
ZINC28900610 agonist Compound 21 EC50 = 0.19 µM PMID: 17553678
PPAR_beta
ZINC28900615 agonist Compound 22 EC50 = 1.2 µM PMID: 17553678
ZINC28900634 agonist Compound 24 R EC50 = 0.002 µM PMID: 17553678
PPAR_beta
ZINC28900640 agonist Compound 24 S EC50 = 0.13 µM PMID: 17553678
PPAR_beta
ZINC28900750 agonist Compound 35 R EC50 = 0.003 µM PMID: 17553678
PPAR_beta
ZINC28900755 agonist Compound 35 S EC50 = 0.02 µM PMID: 17553678
PPAR_beta
ZINC28900759 agonist Compound 36 R EC50 = 0.001 µM PMID: 17553678
PPAR_beta
ZINC28900764 agonist Compound 36 S EC50 = 0.01 µM PMID: 17553678
PPAR_beta
ZINC28948386 agonist Compound 2 EC50 = 0.3 µM PMID: 17379517
PPAR_beta
ZINC28948388 agonist Compound 3 EC50 = 0.02 µM PMID: 17379517
PPAR_beta
ZINC28948390 agonist Compound 4 EC50 = 0.06 µM PMID: 17379517
PPAR_beta
ZINC28948392 agonist Compound 5 EC50 = 0.02 µM PMID: 17379517
PPAR_beta
ZINC28948394 agonist Compound 6 EC50 = 0.002 µM PMID: 17379517
PPAR_beta
ZINC28948396 agonist Compound 7 EC50 = 0.004 µM PMID: 17379517
PPAR_beta
ZINC28948398 agonist Compound 8 EC50 = 0.02 µM PMID: 17379517
PPAR_beta
ZINC28948417 agonist Compound 11 EC50 = 0.5 µM PMID: 17379517 PPAR_gamma
ZINC28948423 agonist Compound 12 EC50 = 0.09 µM PMID: 17379517 PPAR_gamma
ZINC28948425 agonist Compound 13 EC50 = 0.03 µM PMID: 17379517 PPAR_gamma
ZINC28948431 agonist Compound 14 EC50 = 14 µM PMID: 17379517 PPAR_gamma
ZINC28948819 agonist Compound 9 EC50 = 0.02 µM PMID: 17379517
PPAR_beta
ZINC28949095 agonist Compound 1a IC50 = 0.090 µM EC50 = 0.022 +/- 0.0063 µM PMID: 17292606 PPAR_gamma
ZINC28949099 agonist Compound 1b IC50 = 0.075 µM EC50 = 0.044 +/- 0.0346 µM PMID: 17292606 PPAR_gamma
ZINC28949101 agonist Compound 1c IC50 = 0.051 µM EC50 = 0.047 +/- 0.0080 µM PMID: 17292606 PPAR_gamma
ZINC28949106 agonist Compound 1d IC50 = 0.11 µM EC50 = 0.030 +/- 0.0184 µM PMID: 17292606 PPAR_gamma
ZINC28949110 agonist Compound 1e IC50 = 0.083 µM EC50 = 0.062 +/- 0.0641 µM PMID: 17292606 PPAR_gamma
ZINC28949115 agonist Compound 1f IC50 = 0.387 µM EC50 = 0.324 +/- 0.1679 µM PMID: 17292606 PPAR_gamma
ZINC28949118 agonist Compound 1g IC50 = 0.034 µM EC50 = 0.005 µM PMID: 17292606 PPAR_gamma
ZINC28949121 agonist Compound 1h IC50 = 0.149 µM EC50 = 0.313 +/- 1.080 µM PMID: 17292606 PPAR_gamma
ZINC28949141 agonist Compound 2e IC50 = 1.8 µM EC50 = 0.128 +/- 0.0760 µM PMID: 17292606 PPAR_gamma
ZINC28949144 agonist Compound 2f IC50 = 0.088 µM EC50 = 0.004 +/- 0.0003 µM PMID: 17292606 PPAR_gamma
ZINC28949149 agonist Compound 2g IC50 = 0.97 µM EC50 = 0.035 +/- 0.0088 µM PMID: 17292606 PPAR_gamma
ZINC28949150 agonist Compound 2h IC50 = 1.05 µM EC50 = 0.189 +/- 0.1535 µM PMID: 17292606 PPAR_gamma
ZINC28949152 agonist Compound 2i IC50 = 0.14 µM EC50 = 0.021 +/- 0.0111 µM PMID: 17292606 PPAR_gamma
ZINC28949154 agonist Compound 2j IC50 = 0.68 µM EC50 = 0.618 +/- 0.1654 µM PMID: 17292606 PPAR_gamma
ZINC28949160 agonist Compound 2l IC50 = 1.8 µM EC50 = 0.871 +/- 0.4624 µM PMID: 17292606 PPAR_gamma
ZINC28951915 agonist Compound 9 EC50 = 2464 nM PMID: 17601734
ZINC28951917 agonist Compound 1 EC50 = 890 nM PMID: 17601734
ZINC28951919 agonist Compound 5 EC50 = 2190 nM PMID: 17601734
ZINC28951924 agonist Compound 7 EC50 = 7470 nM PMID: 17601734
ZINC28951937 agonist Compound 10 EC50 = 798 nM PMID: 17601734
ZINC28951939 agonist Compound 11 EC50 = 1890 nM PMID: 17601734
ZINC28951941 agonist Compound 12 EC50 = 78 nM PMID: 17601734
ZINC28951943 agonist Compound 13 EC50 = 546 nM PMID: 17601734
ZINC28951945 agonist Compound 14 EC50 = 300 nM PMID: 17601734
ZINC28951947 agonist Compound 15 EC50 = 1690 nM PMID: 17601734
ZINC28951949 agonist Compound 16 EC50 = 504 nM PMID: 17601734
ZINC28951951 agonist Compound 17 EC50 = 2718 nM PMID: 17601734
ZINC28951954 agonist Compound 18 EC50 = 444 nM PMID: 17601734
ZINC28951956 agonist Compound 19 EC50 = 1152 nM PMID: 17601734
ZINC28951958 agonist Compound 20 EC50 = 9975 nM PMID: 17601734
ZINC28951962 agonist Compound 22 EC50 = 1573 nM PMID: 17601734
ZINC28951964 agonist Compound 23 EC50 = 1188 nM PMID: 17601734
ZINC28971898 agonist Compound (R)-(-)-33 EC50 = 0.146 µM PMID: 18029176
ZINC28971902 agonist Compound (S)-(+)-33 EC50 = 1.11 µM PMID: 18029176
ZINC28971916 agonist Compound (R)-(-)-35 EC50 = 0.002 µM PMID: 18029176
ZINC28978764 agonist Compound 6 EC50 = 0.45 µM PMID: 18060776
ZINC28978814 agonist Compound 10 EC50 = 0.06 µM PMID: 18060776
ZINC28978818 agonist Compound 12 EC50 = 0.05 µM PMID: 18060776
ZINC28978826 agonist Compound 11 EC50 = 1 µM PMID: 18060776
ZINC28978845 agonist Compound 13 EC50 = 0.32 µM PMID: 18060776 PPAR_gamma
ZINC28978854 agonist Compound 14 EC50 = 0.0003 µM PMID: 18060776
PPAR_beta
ZINC28978856 agonist Compound 15 EC50 = 0.003 µM PMID: 18060776 PPAR_gamma
ZINC28978865 agonist Compound 16 EC50 = 0.08 µM PMID: 18060776
ZINC28978874 agonist Compound 19 EC50 = 0.06 µM PMID: 18060776
ZINC28978887 agonist Compound 25 EC50 = 5 µM PMID: 18060776
ZINC28978929 agonist Compound 20 EC50 = 0.005 µM PMID: 18060776 PPAR_gamma
ZINC28978935 agonist Compound 26 EC50 = 0.07 µM PMID: 18060776
ZINC28978939 agonist Compound 21 EC50 = 0.02 µM PMID: 18060776
ZINC28978946 agonist Compound 27 EC50 = 1 µM PMID: 18060776
ZINC28978953 agonist Compound 22 EC50 = 0.36 µM PMID: 18060776
ZINC28978962 agonist Compound 28 EC50 = 3 µM PMID: 18060776
ZINC28979022 agonist Compound 23 EC50 = 0.08 µM PMID: 18060776
ZINC28979026 agonist Compound 29 EC50 = 2.8 µM PMID: 18060776
ZINC28979031 agonist Compound 24 EC50 = 0.08 µM PMID: 18060776
ZINC28979036 agonist Compound 30 EC50 = 6 µM PMID: 18060776
ZINC29043827 agonist Compound 17a IC50 = 1.17 µM EC50 = 0.028 µM PMID: 18511276 PPAR_gamma
ZINC29045250 agonist Compound 13d IC50 = 0.97 µM EC50 = 0.04 µM PMID: 18511276 PPAR_gamma
ZINC29045403 agonist Compound 13b IC50 = 1.328 µM EC50 = 0.089 µM PMID: 18511276 PPAR_gamma
ZINC29045554 agonist Compound 31b IC50 = 0.016 µM EC50 = 0.004 µM PMID: 18511276 PPAR_gamma
ZINC29045666 agonist Compound 31a IC50 = 0.13 µM EC50 = 0.006 µM PMID: 18511276 PPAR_gamma
ZINC29046011 agonist Compound 13a IC50 = 2.56 µM EC50 = 0.235 µM PMID: 18511276 PPAR_gamma
ZINC29046131 agonist Compound 14a IC50 = 0.255 µm EC50 = 0.056 µM PMID: 18511276 PPAR_gamma
ZINC29057355 agonist Compound 79 EC50 = 86 nM PMID: 18155554 PPAR_beta
ZINC29057646 agonist Compound 75 EC50 = 123 nM PMID: 18155554
PPAR_beta
ZINC29057808 agonist Compound 70 EC50 = 37 nM PMID: 18155554
PPAR_beta
ZINC29058101 agonist Compound 55 EC50 = 70 nM PMID: 18155554
PPAR_beta
ZINC29058105 agonist Compound 50 EC50 = 115 nM PMID: 18155554 PPAR_beta
ZINC29058241 agonist Compound 45 EC50 = 476 nM PMID: 18155554 PPAR_beta
ZINC29058249 agonist Compound 40 EC50 = 100 nM PMID: 18155554 PPAR_beta
ZINC29058367 agonist Compound 30 EC50 = 34 nM PMID: 18155554
PPAR_beta
ZINC29058372 agonist Compound 35 EC50 = 28 nM PMID: 18155554 PPAR_beta
ZINC29058615 agonist Compound 20 EC50 = 2208 nM PMID: 18155554 PPAR_beta
ZINC29058747 agonist Compound 10 EC50 = 1290 nM PMID: 18155554 PPAR_beta
ZINC29059179 agonist Compound 86 EC50 = 155 nM PMID: 18155554 PPAR_beta
ZINC29059200 agonist Compound 82 EC50 = 643 nM PMID: 18155554 PPAR_beta
ZINC29059206 agonist Compound 83 EC50 = 297 nM PMID: 18155554 PPAR_beta
ZINC29059402 agonist Compound 80 EC50 = 97 nM PMID: 18155554 PPAR_beta
ZINC29059409 agonist Compound 81 EC50 = 504 nM PMID: 18155554 PPAR_beta
ZINC29126096 agonist Compound 3 EC50 = 0.3 µM PMID: 17964792 PPAR_gamma
ZINC29126100 agonist Compound 3 EC50 = 0.3 µM PMID: 18280733 PPAR_gamma
ZINC29126733 agonist Compound 4c EC50 = 0.1 µM PMID: 18280733 PPAR_gamma
ZINC29127122 agonist Compound 13 EC50 = 500 nM PMID: 18162399
PPAR_beta
ZINC29127161 agonist TIPP703 EC50 = 61 nM PMID: 18162399
PPAR_beta
ZINC29132176 agonist Compound 20 %inhibition = 25.4 PMID: 18083521
PPAR_beta
ZINC29132182 agonist Compound 18 %inhibition = 8.5 PMID: 18083521
PPAR_beta
ZINC29132184 agonist Compound 19 %inhibition = 33.5 PMID: 18083521
PPAR_beta
ZINC29132261 agonist Compound 16 %inhibition = 20.3 PMID: 18083521
PPAR_beta
ZINC29132263 agonist Compound 17 %inhibition = 10.9 PMID: 18083521
PPAR_beta
ZINC29132264 agonist Compound 14 %inhibition = 18.3 PMID: 18083521
PPAR_beta
ZINC29132266 agonist Compound 15 %inhibition = 22.5 PMID: 18083521
PPAR_beta
ZINC29132316 agonist Compound 24 EC50 = 0.3 µM PMID: 17964792
ZINC29132399 agonist Compound 16 EC50 = 0.03 µM PMID: 17964792
ZINC29132401 agonist Compound 22 EC50 = 0.3 µM PMID: 17964792
ZINC29132404 agonist Compound 14j EC50 = 0.03 µM PMID: 17964792
ZINC29132489 agonist Compound 14h EC50 = 0.3 µM PMID: 17964792
ZINC29132589 agonist Compound 14f EC50 = 0.01 µM PMID: 17964792
ZINC29132595 agonist Compound 14e EC50 = 0.01 µM PMID: 17964792 PPAR_gamma
ZINC29132642 agonist Compound 6 %inhibition = 36.2 PMID: 18083521
PPAR_beta
ZINC29132644 agonist Compound 7 %inhibition = 28.4 PMID: 18083521
PPAR_beta
ZINC29132646 agonist Compound 8 %inhibition = 21.3 PMID: 18083521
PPAR_beta
ZINC29132671 agonist Compound 14c EC50 = 0.03 µM PMID: 17964792
ZINC29132726 agonist Compound 14a EC50 = 0.03 µM PMID: 17964792
ZINC29132728 agonist Compound 14b EC50 = 0.03 µM PMID: 17964792
ZINC32207668 agonist Compound 12 %inhibition = 22.2 PMID: 18083521
PPAR_beta
ZINC34001583 agonist Compound 4 EC50 = 8.6 µM PMID: 21515063
PPAR_beta
ZINC34044490 agonist Compound 5 EC50 = 0.3 µM PMID: 15713415 PPAR_beta
ZINC34049113 agonist imiglitazar EC50 = 0.008 µM PMID: 18976908 PPAR_gamma
ZINC34058612 agonist pristanic acid EC50 = 3 µM PMID: 11060349
ZINC34097435 agonist Compound 26 IC50 = 363 nM EC50 = 0.35 µM PMID: 16737814 PPAR_gamma
ZINC34210397 agonist Compound 28 IC50 = 61 nM EC50 = 0.02 µM PMID: 16737814
PPAR_beta
ZINC34298670 agonist Compound 25f EC50 = 0.01 +/- 0.01 µM PMID: 17243659
ZINC34313371 agonist Compound 27 EC50 = 0.24 µM PMID: 17243659
ZINC34313754 agonist Compound (S)-2Ae IC50 = 0.048 µM EC50 = 0.061 µM PMID: 19349176 PPAR_gamma
ZINC34351362 agonist Compound 25g EC50 = 0.04 µM PMID: 17243659
ZINC34357149 agonist Compound (S)-2Ca IC50 = 0.393 µM EC50 = 0.013 µM PMID: 19349176 PPAR_gamma
ZINC34357232 agonist Compound 25b EC50 = 0.005 +/- 0.000 µM PMID: 17243659 PPAR_gamma
ZINC34359096 agonist Compound 37 EC50 = 0.11 +/- 0.05 µM PMID: 17243659
ZINC34359717 agonist Compound 57 IC50 = 0.529 µM EC50 = 1.6 µM PMID: 18394907
ZINC34390133 agonist Compound 25h EC50 = 0.12 +/- 0.02 µM PMID: 17243659
ZINC34393524 agonist Compound 14a EC50 = 5.0 +/- 1.3 nM PMID: 21530275 PPAR_beta
ZINC34443936 agonist Compound 28 EC50 = 0.730 µM PMID: 18947994 PPAR_gamma
ZINC34471017 agonist Compound 13 IC50 = 4684 nM EC50 = 561 nM PMID: 17005393 PPAR_gamma
ZINC34575834 agonist Compound 12 Ki = 4.8 µM EC50 = 0.0882 µM PMID: 16979341
ZINC34598049 agonist Compound (R)-4f EC50 = 1.2 µM PMID: 22133631
ZINC34598050 agonist Compound (S)-4f EC50 = 0.008 µM PMID: 22133631 PPAR_beta
ZINC34638474 agonist Compound 1 EC50 = 114 nM PMID: 19376700 PPAR_gamma
ZINC34639588 agonist Compound 12b EC50 = 35.9 +/- 2.7 µM PMID: 19791744
ZINC34717656 agonist gw2331 IC50 = 0.538 +/- 0.165 µM EC50 < 0.02 µM PMID: 15771468
ZINC34717672 agonist Compound 27 IC50 = 40 nM EC50 = 0.51 µM PMID: 16737814
PPAR_beta
ZINC34717674 agonist Compound 22 IC50 = 181 nM EC50 = 0.02 µM PMID: 16737814 PPAR_gamma
ZINC34717676 agonist Compound 12 IC50 = 125 nM EC50 = 0.83 µM PMID: 16737814 PPAR_gamma
ZINC34717680 agonist Compound 17 IC50 = 121 nM EC50 = 0.63 µM PMID: 16737814 PPAR_gamma
ZINC34717682 agonist Compound 7 IC50 = 368 nM EC50 = 0.84 µM PMID: 16737814 PPAR_gamma
ZINC34717685 agonist Compound 20 IC50 = 117 nM EC50 = 0.41 µM PMID: 16737814 PPAR_gamma
ZINC34717687 agonist Compound 21 IC50 = 173 nM EC50 = 0.73 M PMID: 16737814 PPAR_gamma
ZINC34717689 agonist Compound 16 IC50 = 396 nM EC50 = 0.13 µM PMID: 16737814 PPAR_gamma
ZINC34717691 agonist Compound 23 IC50 = 419 nM EC50 = 0.03 µM PMID: 16737814 PPAR_gamma
ZINC34717695 agonist Compound 29 IC50 = 218 nM EC50 = 0.17 µM PMID: 16737814 PPAR_gamma
ZINC34717697 agonist Compound 19 IC50 = 166 nM EC50 = 0.07 µM PMID: 16737814 PPAR_gamma
ZINC34717698 agonist Compound 11 IC50 = 735 nM EC50 = 1µM PMID: 16737814 PPAR_gamma
ZINC34717700 agonist Compound 18 IC50 = 4386 +/- 0 nM EC50 = 2067 +/- 424 nM PMID: 16970391
PPAR_beta
ZINC34717701 agonist Compound 6 IC50 = 1398 +/- 0 nM EC50 = 710 +/- 278 nM PMID: 16970391
PPAR_beta
ZINC34717702 agonist Compound 17 IC50 = 1037 +/- 61 nM EC50 = 488 +/- 0 nM PMID: 16970391
PPAR_beta
ZINC34717703 agonist Compound 19 IC50 = 2681 +/- 145 nM EC50 = 2224 +/- 0 nM PMID: 16970391
PPAR_beta
ZINC34717704 agonist Compound 20 IC50 = 6932 +/- 677 nM EC50 = 2800 +/- 33 nM PMID: 16970391
PPAR_beta
ZINC34717709 agonist Compound 13 IC50 = 10897 +/- 0 nM EC50 = 2813 +/- 136 nM PMID: 16970391
PPAR_beta
ZINC34717711 agonist Compound 15 IC50 = 5303 +/- 466 nM EC50 = 2204 +/- 183 nM PMID: 16970391
PPAR_beta
ZINC34717712 agonist Compound 16 IC50 = 897 +/- 117 nM EC50 = 642 +/- 154 nM PMID: 16970391
PPAR_beta
ZINC34717743 agonist Compound 11 Ki = 6.8 µM EC50 = 0.534 µM PMID: 16973358 PPAR_gamma
ZINC34717744 agonist Compound 12 Ki = 0.18 µM EC50 = 0.083 µM PMID: 16973358 PPAR_gamma
ZINC34717746 agonist Compound 13 Ki = 0.043 µM EC50 = 0.033 µM PMID: 16973358 PPAR_gamma
ZINC34717748 agonist Compound 14 S Ki = 0.57 µM EC50 = 0.111 µM PMID: 16973358 PPAR_gamma
ZINC34717750 agonist Compound 13 S Ki = 1.6 µM EC50 = 0.226 µM PMID: 16979341 PPAR_gamma
ZINC34717751 agonist Compound 36 Ki = 0.013 µM EC50 = 0.133 µM PMID: 16973358 PPAR_gamma
ZINC34717753 agonist Compound 8 Ki = 3.7 µM EC50 = 3.14 µM PMID: 16979341
ZINC34717756 agonist Compound 15 IC50 = 441 +/- 124 nM EC50 = 515 +/- 86 nM PMID: 17005394 PPAR_gamma
ZINC34717757 agonist Compound 16 44 % at 100 µM EC50 = 6.15 µM PMID: 16973358 PPAR_gamma
ZINC34717760 agonist Compound 17 Ki = 0.633 µM EC50 = 0.238 µM PMID: 16973358 PPAR_gamma
ZINC34717761 agonist Compound 17 IC50 = 4962 +/- 842 nM EC50 = 2801 +/- 127 nM PMID: 17005394 PPAR_gamma
ZINC34717762 agonist Compound 15 IC50 = 8399 +/- 354 nM EC50 = 2780 +/- 89 PMID: 17005393 PPAR_gamma
ZINC34717763 agonist Compound 16 IC50 = 3415 +/- 339 nM EC50 = 1715 +/- 290 nM PMID: 17005393 PPAR_gamma
ZINC34717765 agonist Compound 18 IC50 = 3390 +/- 1064 nM EC50 = 2940 +/- 46 nM PMID: 17005394 PPAR_gamma
ZINC34717766 agonist Compound 19 IC50 = 146 +/- 33 nM EC50 = 70 +/- 13 nM PMID: 17005394 PPAR_gamma
ZINC34717767 agonist Compound 37 IC50 = 449 +/- 195 nM EC50 = 198 +/- 53 nM PMID: 17005394 PPAR_gamma
ZINC34717768 agonist Compound 19 S Ki = 0.032 µM EC50 = 0.165 µM PMID: 16973358 PPAR_gamma
ZINC34717770 agonist Compound 6 IC50 = 3489 +/- 917 nM EC50 = 845 +/- 66 nM PMID: 17005393 PPAR_gamma
ZINC34717771 agonist Compound 21 Ki = 0.078 µM EC50 = 0.228 µM PMID: 16973358 PPAR_gamma
ZINC34717773 agonist Compound 34 IC50 = 516 +/- 161 nM EC50 = 78 +/- 11 nM PMID: 17005394 PPAR_gamma
ZINC34717777 agonist Compound 15 Ki = 0.84 µM EC50 = 0.886 µM PMID: 16979341
ZINC34717779 agonist Compound 35 IC50 = 9940 +/- 60 nM EC50 = 900 +/- 143 nM PMID: 17005394 PPAR_gamma
ZINC34717782 agonist Compound 27 Ki = 0.031 µM EC50 = 0.023 µM PMID: 16973358 PPAR_gamma
ZINC34717784 agonist Compound 28 Ki = 0.277 µM EC50 = 0.134 µM PMID: 16973358 PPAR_gamma
ZINC34717786 agonist Compound 36 IC50 = 53 +/- 17 nM EC50 = 35 +/- 4 nM PMID: 17005394 PPAR_gamma
ZINC34717787 agonist Compound 38 IC50 = 1495 +/- 342 nM EC50 = 986 +/- 118 nM PMID: 17005394 PPAR_gamma
ZINC34717788 agonist Compound 29 Ki = 0.014 µM EC50 = 0.010 µM PMID: 16973358 PPAR_gamma
ZINC34717790 agonist Compound 30 Ki = 0.099 µM EC50 = 0.046 µM PMID: 16973358 PPAR_gamma
ZINC34717792 agonist Compound 16 Ki = 0.84 µM EC50 = 0.437 µM PMID: 16979341
ZINC34717794 agonist Compound 31 Ki = 0.021 µM EC50 = 0.011 µM PMID: 16973358 PPAR_gamma
ZINC34717796 agonist Compound 17 Ki = 0.15 µM EC50 = 0.048 µM PMID: 16979341
ZINC34717798 agonist Compound 5 Ki = 3.0 µM EC50 = 0.287 µM PMID: 16973358 PPAR_gamma
ZINC34717800 agonist Compound 18 Ki = 1.2 µM EC50 = 1.57 µM PMID: 16979341
ZINC34717802 agonist Compound 33 Ki = 0.065 µM EC50 = 0.486 µM PMID: 16973358 PPAR_gamma
ZINC34717804 agonist Compound 6 Ki = 1.3 µM EC50 = 0.15 µM PMID: 16973358 PPAR_gamma
ZINC34717806 agonist Compound 7 Ki = 0.88 µM EC50 = 0.77µM PMID: 16973358 PPAR_gamma
ZINC34717808 agonist Compound 32 Ki = 0.100 µM EC50 = 0.008 µM PMID: 16973358
ZINC34717810 agonist Compound 8 Ki = 4.1 EC50 = 0.426 µM PMID: 16973358 PPAR_gamma
ZINC34717812 agonist Compound 34 Ki = 0.215 µM EC50 = 0.090 µM PMID: 16973358 PPAR_gamma
ZINC34717814 agonist Compound 19 Ki = 1.1 µM EC50 = 0.867 µM PMID: 16979341
ZINC34717816 agonist Compound 20 Ki = 3.49 µM EC50 = 1.89 µM PMID: 16979341
ZINC34717818 agonist Compound 9 Ki = 0.43 µM EC50 = 1.72 µM PMID: 16973358 PPAR_gamma
ZINC34717820 agonist Compound 35 Ki = 0.314 µM EC50 = 0.031 µM PMID: 16973358 PPAR_gamma
ZINC34717824 agonist Compound 2b IC50 = 1.05 µM EC50 = 0.180 +/- 0.0936 µM PMID: 17292606 PPAR_gamma
ZINC34867419 agonist Compound 28 EC50 = 1330 nM PMID: 16797985
PPAR_beta
ZINC34875784 agonist Compound 18 EC50 = 7.22 µM PMID: 18826205 PPAR_gamma
ZINC35065299 agonist Compound 9 EC50 = 2.078 µM PMID: 17034149
PPAR_beta
ZINC35246678 agonist Compound 14 EC50 = 0.21 +/- 0.08 µM PMID: 17243659
PPAR_beta
ZINC35246685 agonist Compound 19 EC50 = 9.5 +/- 0.5 µM PMID: 17243659
ZINC35246694 agonist Compound 25i EC50 = 0.004 µM PMID: 17243659
ZINC35246701 agonist Compound 34 EC50 = 1.32 µM PMID: 17243659 PPAR_beta
ZINC35246717 agonist Compound 25j EC50 = 0.465 µM PMID: 17243659 PPAR_beta
ZINC35962940 agonist Compound 9b EC50 = 1.8 +/- 0.1 µM PMID: 19791744
ZINC35999854 agonist Compound 10 IC50 = 0.912 µM EC50 = 0.623 µM PMID: 19783444 PPAR_gamma
ZINC36757774 agonist Compound 23 Ki = 420 nM EC50 = 620 nM PMID: 11677135
PPAR_beta
ZINC36757833 agonist Compound 4 EC50 = 0.73 µM PMID: 16546385 PPAR_beta
ZINC36757863 agonist Compound 21a EC50 = 0.34 µM PMID: 16750626 PPAR_beta
ZINC36757864 agonist Compound 24d EC50 = 1.67 µM PMID: 16750626 PPAR_beta
ZINC36757865 agonist Compound 23 EC50 = 103 nM PMID: 16797985
PPAR_beta
ZINC36757866 agonist Compound 22 EC50 = 1010 nM PMID: 16797985
PPAR_beta
ZINC36757867 agonist Compound 21 EC50 = 1401 nM PMID: 16797985
PPAR_beta
ZINC36757868 agonist Compound 16 EC50 = 8391 nM PMID: 16797985
PPAR_beta
ZINC36757869 agonist Compound 5 EC50 = 1068 nM PMID: 16797985
PPAR_beta
ZINC36757870 agonist Compound 7 EC50 = 0.206 µM PMID: 17034149 PPAR_gamma
ZINC36757871 agonist Compound 12 EC50 = 1.099 µM PMID: 17034149
PPAR_beta
ZINC36757872 agonist Compound 11 EC50 = 0.123 µM PMID: 17034149 PPAR_gamma
ZINC36757873 agonist Compound 15 Ki = 15.1 µM EC50 = 4.67 µM PMID: 16973358 PPAR_gamma
ZINC36757876 agonist Compound 45 EC50 = 0.004 +/- 0.002 µM PMID: 17243659
PPAR_beta
ZINC37866917 agonist Compound 6 EC50 = 3.33 µM PMID: 16546385 PPAR_beta
ZINC37866919 agonist Compound 3 EC50 = 1.64 µM PMID: 16546385 PPAR_beta
ZINC37866926 agonist Compound 15 EC50 = 0.22 µM PMID: 16750626 PPAR_beta
ZINC37866930 agonist Compound 24b EC50 = 7.11 µM PMID: 16750626 PPAR_beta
ZINC37866952 agonist Compound 41 EC50 = 1.89 µM PMID: 17243659 PPAR_beta
ZINC37866953 agonist Compound 25d EC50 = 0.01 +/- 0.003 µM PMID: 17243659 PPAR_beta
ZINC37866954 agonist Compound 25c EC50 = 0.004 +/- 0.000 µM PMID: 17243659 PPAR_beta
ZINC38139028 agonist Compound 10 Ki = 0.21 µM EC50 = 6.1 µM PMID: 19464171
PPAR_beta
ZINC38151294 agonist Compound 25k EC50 = 5.64 +/- 0.29 µM PMID: 17243659
ZINC38151296 agonist Compound 25e EC50 = 0.03 +/- 0.01 µM PMID: 17243659
ZINC38155988 agonist Compound 28 IC50 = 10 nM EC50 = 7.8 nM PMID: 16384704
ZINC38158119 agonist Compound 8b EC50 = 0.30 +/- 0.044 µM PMID: 14584939
PPAR_beta
ZINC38310496 agonist Compound 30 EC50 = 0.008 µM PMID: 18947994
PPAR_beta
ZINC38320570 agonist Compound 8 EC50 = 0.020 µM PMID: 18947994
PPAR_beta
ZINC38323523 agonist Compound 25 EC50 = 0.020 µM PMID: 18947994
PPAR_beta
ZINC38323742 agonist Compound 15 EC50 = 0.032 µM PMID: 18947994 PPAR_gamma
ZINC38336531 agonist Compound 26 EC50 = 0.090 µM PMID: 18947994 PPAR_gamma
ZINC38362582 agonist Compound 15 EC50 = 0.13 µM PMID: 19301897 PPAR_gamma
ZINC38396199 agonist Compound 17e EC50 = 0.899 µM EC50 = 0.74 µM PMID: 19783444 PPAR_gamma
ZINC38448923 agonist Compound 66 IC50 = 1.9 µM EC50 = 2.3 µM PMID: 18394907 PPAR_gamma
ZINC38471554 agonist Compound 14c EC50 = 0.30 µM PMID: 22197396 PPAR_gamma
ZINC40331238 agonist Compound 54 IC50 = 1.43 µM EC50 = 5µM PMID: 18394907 PPAR_gamma
ZINC40379961 agonist Compound 12 EC50 = 0.050 µM PMID: 18947994
PPAR_beta
ZINC40380487 agonist Compound 10 EC50 = 0.045 µM PMID: 18947994
PPAR_beta
ZINC40391278 agonist Compound 16 EC50 = 0.066 µM PMID: 18947994
PPAR_beta
ZINC40392616 agonist Compound 14 EC50 = 0.045 µM PMID: 18947994
PPAR_beta
ZINC40393734 agonist Compound 6 EC50 = 0.050 µM PMID: 18947994
PPAR_beta
ZINC40395284 agonist Compound 13i EC50 = 4.2 µM PMID: 18625559 PPAR_gamma
ZINC40395377 agonist Compound 13a EC50 = 1.09 µM PMID: 18625559 PPAR_gamma
ZINC40395577 agonist Compound 13f EC50 = 0.6 µM PMID: 18625559 PPAR_gamma
ZINC40395608 agonist Compound 13d EC50 = 0.089 µM PMID: 18625559 PPAR_gamma
ZINC40403829 agonist Compound 23 EC50 = 0.094 µM PMID: 18947994 PPAR_gamma
ZINC40404981 agonist Compound (S)-5b EC50 = 1.73 µM PMID: 18771917 PPAR_gamma
ZINC40405720 agonist Compound (S)-28 EC50 = 1.12 +/- 0.08 µM PMID: 18835719 PPAR_gamma
ZINC40406108 agonist Compound (R)-27 EC50 = 11.30 +/- 5.23 µM PMID: 18835719 PPAR_gamma
ZINC40409323 agonist Compound 28 IC50 = 0.330 µM EC50 = 1 µM PMID: 18394907 PPAR_gamma
ZINC40410758 agonist Compound (S)-3Bb IC50 = 0.905 µM EC50 = 0.011 µM PMID: 19349176 PPAR_gamma
ZINC40412686 agonist Compound (S)-2Ga IC50 = 0.021 µM EC50 = 0.027 µM PMID: 19349176 PPAR_gamma
ZINC40413241 agonist Compound (S)-4Ba IC50 = 0.333 µM EC50 = 0.058 µM PMID: 19349176 PPAR_gamma
ZINC40413451 agonist Compound (S)-2Bb IC50 = 0.063 µM EC50 = 0.089 µM PMID: 19349176 PPAR_gamma
ZINC40420188 agonist Compound 20 EC50 = 0.072 µM PMID: 18976908 PPAR_gamma
ZINC40420651 agonist Compound (S)-2Ab IC50 = 0.053 µM EC50 = 0.002 µM PMID: 19349176 PPAR_gamma
ZINC40421027 agonist Compound 9b EC50 = 0.044 µM PMID: 18976908 PPAR_gamma
ZINC40422975 agonist Compound (S)-5r EC50 = 0.615 µM PMID: 18771917 PPAR_gamma
ZINC40423420 agonist Compound 17 EC50 = 5.90 µM PMID: 18826205 PPAR_gamma
ZINC40423527 agonist Compound S-4 EC50 = 0.15 +/- 0.04 µM PMID: 19775169 PPAR_gamma
ZINC40429388 agonist Compound 14 EC50 = 0.03 µM PMID: 19301897
ZINC40847207 agonist Compound 4 EC50 = 0.16 µM PMID: 18947994
PPAR_beta
ZINC40865720 agonist Compound 2 EC50 = 1.0 +/- 0.2 µM PMID: 20307981
ZINC40866358 agonist Compound 17 EC50 = 0.042 µM PMID: 18947994 PPAR_gamma
ZINC40872869 agonist Compound 5 EC50 = 0.383 µM PMID: 18947994 PPAR_gamma
ZINC40876346 agonist Compound 13g EC50 = 0.03 µM PMID: 18625559 PPAR_gamma
ZINC40879926 agonist Compound 13c EC50 = 0.272 µM PMID: 18625559 PPAR_gamma
ZINC40891654 agonist Compound 29 EC50 = 0.085 µM PMID: 18947994
PPAR_beta
ZINC40892620 agonist Compound (S)-30 EC50 = 3.65 +/- 1.23 µM PMID: 18835719 PPAR_gamma
ZINC40913431 agonist Compound (S)-29 EC50 = 0.59 +/- 0.02 µM PMID: 18835719 PPAR_gamma
ZINC40914961 agonist Compound (S)-27 EC50 = 0.87 +/- 0.19 µM PMID: 18835719 PPAR_gamma
ZINC40934024 agonist Compound 13a EC50 = 0.0000038 µM PMID: 18976908 PPAR_gamma
ZINC40934025 agonist Compound 13b EC50 = 0.002 µM PMID: 18976908 PPAR_gamma
ZINC40934174 agonist Compound 13c EC50 = 0.0001 µM PMID: 18976908 PPAR_gamma
ZINC40936783 agonist Compound 9c EC50 = 0.034 µM PMID: 18976908 PPAR_gamma
ZINC40937335 agonist Compound (S)-4Aa IC50 = 0.028 µM EC50 = 0.157 µM PMID: 19349176 PPAR_gamma
ZINC40937683 agonist Compound (S)-2Gd IC50 = 0.037 µM EC50 = 0.016 µM PMID: 19349176 PPAR_gamma
ZINC40938791 agonist Compound (S)-2Bf IC50 = 0.194 µM EC50 = 0.167 µM PMID: 19349176 PPAR_gamma
ZINC40939033 agonist Compound (S)-2Fa IC50 = 0.060 µM EC50 = 0.555 µM PMID: 19349176 PPAR_gamma
ZINC40939173 agonist Compound 24 EC50 = 4.06 µM PMID: 18826205 PPAR_gamma
ZINC40939498 agonist Compound 23 EC50 = 13.1 µM PMID: 18826205 PPAR_gamma
ZINC40939500 agonist Compound 25 EC50 = 12.1 µM PMID: 18826205 PPAR_gamma
ZINC40940331 agonist Compound (S)-3Ba IC50 = 0.198 µM EC50 = 0.011 µM PMID: 19349176 PPAR_gamma
ZINC40940615 agonist Compound (S)-2Ad IC50 = 0.045 µM EC50 = 0.020 µM PMID: 19349176 PPAR_gamma
ZINC40950621 agonist Compound 16 EC50 = 2.91 µM PMID: 18826205 PPAR_gamma
ZINC40950935 agonist Compound 84 EC50 = 5.60 µM PMID: 18826205 PPAR_gamma
ZINC40951015 agonist Compound 19 EC50 = 2.70 µM PMID: 18826205 PPAR_gamma
ZINC40951018 agonist Compound 21 EC50 = 2.95 µM PMID: 18826205 PPAR_gamma
ZINC40952198 agonist Compound 85 EC50 = 30.4 µM PMID: 18826205 PPAR_gamma
ZINC40979174 agonist Compound 20 EC50 = 0.674 µM PMID: 18826205 PPAR_gamma
ZINC41567617 agonist Compound 37 EC50 = 9.1 +/- 0.9 µM PMID: 21889235
ZINC42804043 agonist Compound 11 EC50 = 1.92 µM PMID: 19301897 PPAR_gamma
ZINC42808475 agonist Compound 9 EC50 = 467 +/- 79 nM PMID: 18952442
ZINC42833889 agonist Compound 8 EC50 = 0.13 µM PMID: 19301897 PPAR_gamma
ZINC42833932 agonist Compound (S)-3Ff IC50 = 0.429 µM EC50 = 0.987 µM PMID: 19349176 PPAR_gamma
ZINC42834179 agonist Compound 19 EC50 = 3.99 µM PMID: 19301897 PPAR_gamma
ZINC42852631 agonist Compound 8 EC50 = 223 +/- 52 nM PMID: 18952442
ZINC42875255 agonist Compound (S)-4l EC50 = 12 +/- 1 nM PMID: 18662876
PPAR_beta
ZINC42875604 agonist Compound 19 EC50 = 0.20 µM PMID: 18947994 PPAR_gamma
ZINC42890958 agonist Compound 6 EC50 = 0.13 µM PMID: 19301897 PPAR_gamma
ZINC42921106 agonist Compound 25 EC50 = 13.8 +/- 3.4 µM PMID: 19556125
PPAR_beta
ZINC42965122 agonist Compound 3c EC50 = 9 nM PMID: 19376700 PPAR_gamma
ZINC43009893 agonist Compound 12g IC50 = 2981 nM EC50 = 370 nM PMID: 19530681 PPAR_gamma
ZINC43009896 agonist Compound 12h IC50 = 491 nM EC50 = 2 nM PMID: 19530681 PPAR_gamma
ZINC43009979 agonist Compound 12d IC50 = 2624 nM EC50 = 230 nM PMID: 19530681 PPAR_gamma
ZINC43022184 agonist Compound 21 EC50 = 0.60 +/- 0.12 µM PMID: 19556125
PPAR_beta
ZINC43060453 agonist Compound (S)-11 EC50 = 1.7 +/- 0.18 µM PMID: 19556125 PPAR_gamma
ZINC43060456 agonist Compound (R)-11 EC50 = 0.011 +/- 0.004 µM PMID: 19556125 PPAR_gamma
ZINC43065700 agonist Compound 3b EC50 = 34 nM PMID: 19376700 PPAR_gamma
ZINC43068539 agonist Compound 27 EC50 = 1.5 +/- 0.25 µM PMID: 19556125 PPAR_gamma
ZINC43078296 agonist Compound 12k IC50 = 1081 nM EC50 = 185 nM PMID: 19530681 PPAR_gamma
ZINC43078627 agonist Compound 3a EC50 = 73 nM PMID: 19376700 PPAR_gamma
ZINC43200300 agonist Compound 2a EC50 = 64 nM PMID: 20356736 PPAR_gamma
ZINC43200301 agonist Compound 2l EC50 = 46.6 nM PMID: 20356736 PPAR_gamma
ZINC43200302 agonist Compound 2s EC50 = 13 nM PMID: 20356736 PPAR_gamma
ZINC43606240 agonist Compound (R)-(-)-32 EC50 = 0.169 µM PMID: 18029176
ZINC43640915 agonist Compound 5 %inhibition = 11.4 PMID: 18083521
PPAR_beta
ZINC44280935 agonist Compound 20 EC50 = 1000 nM PMID: 19275963
PPAR_beta
ZINC44281357 agonist Compound 12 EC50 = 4.07 µM PMID: 19301897 PPAR_gamma
ZINC44305553 agonist Compound 10 EC50 = 0.03 µM PMID: 19301897 PPAR_gamma
ZINC44350697 agonist Compound 9 EC50 = 0.03 µM PMID: 19301897 PPAR_gamma
ZINC44351663 agonist Compound 17 EC50 = 0.12 µM PMID: 19301897 PPAR_gamma
ZINC44351925 agonist Compound 18 EC50 = 0.24 µM PMID: 19301897 PPAR_gamma
ZINC44352339 agonist Compound 2 EC50 = 0.2 µM PMID: 19301897 PPAR_gamma
ZINC44352615 agonist Compound 4 EC50 = 183 +/- 43 nM PMID: 18952442
ZINC44358478 agonist Compound 18 EC50 = 0.57 µM PMID: 18947994
ZINC44359368 agonist Compound (R)-4l EC50 = 200 +/- 30 nM PMID: 18662876
PPAR_beta
ZINC44386320 agonist Compound 5 EC50 = 524 +/- 69 nM PMID: 18952442
ZINC44418541 agonist Compound 29 EC50 = 1000 nM PMID: 19275963 PPAR_gamma
ZINC44460340 agonist Compound 12 IC50 = 347.0 nM EC50 = 8.8 nM PMID: 20218621 PPAR_gamma
ZINC44460341 agonist BMS687453 EC50 = 9.6 nM PMID: 20356736 PPAR_gamma
ZINC45244963 agonist (S)-12l EC50 = 55.9 +/- 5.2 µM PMID: 19791744
ZINC45244964 agonist (R)-12l EC50 = 73.5 +/- 6.8 µM PMID: 19791744
ZINC45253822 agonist (S)-12o EC50 = 1.9 +/- 0.1 µM PMID: 19791744
ZINC45284038 agonist Compound S-2 EC50 = 0.0115 +/- 0.0021 µM PMID: 19775169
ZINC45284041 agonist Compound R-2 EC50 = 2.4 +/- 0.8 µM PMID: 19775169 PPAR_gamma
ZINC45284361 agonist Compound 12h EC50 = 45.8 +/- 4.0 µM PMID: 19791744
ZINC45285481 agonist Compound 12j EC50 = 36.1 +/- 2.9 µM PMID: 19791744
ZINC45286962 agonist (R)-12o EC50 = 57.3 +/- 4.7 µM PMID: 19791744
ZINC45288974 agonist Compound 12g EC50 =38.9 +/- 2.5 µM PMID: 19791744
ZINC45299607 agonist Compound 12d EC50 = 46.3 +/- 3.6 µM PMID: 19791744
ZINC45300230 agonist Compound 12f EC50 = 45.8 +/- 3.9 µM PMID: 19791744
ZINC45315131 agonist Compound 12k EC50 = 69.3 +/- 5.4 µM PMID: 19791744
ZINC45319006 agonist Compound 12c EC50 = 2.5 +/- 0.1 µM PMID: 19791744
ZINC45335524 agonist Compound 9d EC50 = 0.01 µM PMID: 20022492 PPAR_gamma
ZINC45335620 agonist Compound 9i EC50 = 0.03 µM PMID: 20022492 PPAR_gamma
ZINC45335809 agonist Compound 9e EC50 = 0.4 µM PMID: 20022492 PPAR_gamma
ZINC45335818 agonist Compound 9f EC50 = 2.4 µM PMID: 20022492 PPAR_gamma
ZINC45336592 agonist Compound 9n EC50 = 0.4 µM PMID: 20022492 PPAR_gamma
ZINC45338002 agonist Compound 9b EC50 = 0.05 µM PMID: 20022492 PPAR_gamma
ZINC45338533 agonist Compound 9g EC50 = 0.5 µM PMID: 20022492 PPAR_gamma
ZINC45338535 agonist Compound 9h EC50 = 0.02 µM PMID: 20022492 PPAR_gamma
ZINC45338737 agonist Compound 9a EC50 = 2.3 µM PMID: 20022492
ZINC45339287 agonist Compound 9j EC50 = 0.003 µM PMID: 20022492 PPAR_gamma
ZINC45339289 agonist Compound 9k EC50 = 0.1 µM PMID: 20022492 PPAR_gamma
ZINC45339291 agonist Compound 9l EC50 = 0.002 µM PMID: 20022492 PPAR_gamma
ZINC45347216 agonist Compound 17a IC50 = 0.676 µM EC50 = 0.685 µM PMID: 19783444
ZINC45375227 agonist Compound 9m EC50 = 0.005 µM PMID: 20022492 PPAR_gamma
ZINC45386701 agonist Compound 9c EC50 = 0.05 µM PMID: 20022492 PPAR_gamma
ZINC45497234 agonist Compound 22 EC50 = 58.8 µM PMID: 18826205 PPAR_gamma
ZINC45505696 agonist Compound 13 EC50 = 0.04 µM PMID: 19301897
PPAR_beta
ZINC45506275 agonist Compound 16 EC50 = 0.05 µM PMID: 19301897
PPAR_beta
ZINC49021465 agonist Compound 25d EC50 = 4.08 µM PMID: 19928766 PPAR_beta
ZINC49021468 agonist Compound 25f EC50 = 0.48 µM PMID: 19928766 PPAR_beta
ZINC49033983 agonist Compound 22 EC50 = 790 nM PMID: 21344906 PPAR_beta
ZINC49036503 agonist Compound 9 EC50 = 2000 nM PMID: 20452212
ZINC49036834 agonist Compound 11 EC50 = 300 nM PMID: 20452212
ZINC49036836 agonist Compound 12 EC50 = 3000 nM PMID: 20452212
ZINC49037044 agonist Compound 5 EC50 = 900 nM PMID: 20452212
ZINC49045684 agonist Compound 13 EC50 = 1500 nM PMID: 20452212
ZINC49046896 agonist Compound 4 EC50 = 700 nM PMID: 20452212
ZINC49047926 agonist Compound 16 EC50 = 7000 nM PMID: 20452212
ZINC49048523 agonist Compound 2e EC50 = 1225 nM PMID: 20356736
ZINC49048575 agonist Compound 2o EC50 = 1453 nM PMID: 20356736 PPAR_gamma
ZINC49049034 agonist Compound 2f EC50 = 451 nM PMID: 20356736
ZINC49049505 agonist Compound 2j EC50 = 87 nM PMID: 20356736 PPAR_gamma
ZINC49049647 agonist Compound 2 EC50 = 20 nM PMID: 20452212
ZINC49049651 agonist Compound 3 EC50 = 1000 nM PMID: 20452212
ZINC49049976 agonist Compound 2m EC50 = 41.8 nM PMID: 20356736 PPAR_gamma
ZINC49050444 agonist Compound 2n EC50 = 304 nM PMID: 20356736
ZINC49051958 agonist Compound 2i EC50 = 73 nM PMID: 20356736
ZINC49054253 agonist Compound 2q EC50 = 145 nM PMID: 20356736 PPAR_gamma
ZINC49054256 agonist Compound 2r EC50 = 22 nM PMID: 20356736 PPAR_gamma
ZINC49066669 agonist Compound 19 IC50 = 362 nM EC50 = 48.6 nM PMID: 20218621
ZINC49067577 agonist Compound 23 IC50 = 473 nM EC50 = 37.0 nM PMID: 20218621 PPAR_gamma
ZINC49067579 agonist Compound 24 IC50 = 375 nM EC50 = 15.8 nM PMID: 20218621 PPAR_gamma
ZINC49068395 agonist Compound 13 IC50 = 485 nM EC50 = 122 nM PMID: 20218621 PPAR_gamma
ZINC49069136 agonist Compound 1b EC50 = 11.13 +/- 5.72 µM PMID: 20299214 PPAR_gamma
ZINC49070602 agonist Compound 25 IC50 = 372 nM EC50 = 9.1 nM PMID: 20218621 PPAR_gamma
ZINC49070766 agonist Compound 26 IC50 = 526 nM EC50 = 8.7 nM PMID: 20218621 PPAR_gamma
ZINC49070899 agonist Compound 17 IC50 = 422 nM EC50 = 134 nM PMID: 20218621 PPAR_gamma
ZINC49072701 agonist Compound 16 IC50 = 420 nM EC50 = 68.0 nM PMID: 20218621 PPAR_gamma
ZINC49088297 agonist Compound 2b EC50 = 68 nM PMID: 20356736 PPAR_gamma
ZINC49088298 agonist Compound 2c EC50 = 29.9 nM PMID: 20356736 PPAR_gamma
ZINC49109356 agonist Compound 2g EC50 = 1086 nM PMID: 20356736
ZINC49109509 agonist Compound 2d EC50 = 235 nM PMID: 20356736
ZINC49109574 agonist Compound 25 EC50 = 130 nM PMID: 21344906 PPAR_beta
ZINC49111118 agonist Compound 2h EC50 = 395 nM PMID: 20356736 PPAR_gamma
ZINC49111162 agonist Compound 2k EC50 = 90 nM PMID: 20356736 PPAR_gamma
ZINC49111814 agonist Compound 1a EC50 = 8.98 +/- 1.14 µM PMID: 20299214 PPAR_gamma
ZINC49112385 agonist Compound 6 EC50 = 1000 nM PMID: 20452212
ZINC49126161 agonist Compound 10 IC50 = 811.2 nM EC50 = 39.1 nM PMID: 20218621
ZINC49774679 agonist Compound 7c EC50 = 2.37 µM PMID: 19928766 PPAR_gamma
ZINC49775064 agonist Compound 8a EC50 = 1.06 µM PMID: 19928766 PPAR_gamma
ZINC49775275 agonist Compound 8c EC50 = 0.80 µM PMID: 19928766 PPAR_gamma
ZINC49775445 agonist Compound 7b EC50 = 5.25 µM PMID: 19928766 PPAR_gamma
ZINC49777805 agonist Compound 2u EC50 = 471 nM PMID: 20356736 PPAR_gamma
ZINC49780465 agonist Compound 2t EC50 = 66 nM PMID: 20356736 PPAR_gamma
ZINC49780746 agonist Compound 9 IC50 = 941.8 nM EC50 = 289.3 nM PMID: 20218621 PPAR_gamma
ZINC49780751 agonist Compound 2a EC50 = 1.45 +/- 0.28 µM PMID: 20299214 PPAR_gamma
ZINC49780806 agonist Compound 2c EC50 = 1.35 +/- 0.04 µM PMID: 20299214 PPAR_gamma
ZINC49780852 agonist Compound 22 IC50 = 1725 nM EC50 = 108 nM PMID: 20218621 PPAR_gamma
ZINC49780952 agonist Compound 15 IC50 = 582 nM EC50 = 90 nM PMID: 20218621 PPAR_gamma
ZINC49781026 agonist Compound 21 IC50 = 2885 nM EC50 = 340 nM PMID: 20218621 PPAR_gamma
ZINC49781032 agonist Compound 27 IC50 = 569 nM EC50 = 12.0 nM PMID: 20218621 PPAR_gamma
ZINC49781081 agonist Compound 2b EC50 = 0.012 +/- 0.002 µM PMID: 20299214 PPAR_gamma
ZINC49781316 agonist Compound 11 IC50 = 610.1 nM EC50 = 16.5 nM PMID: 20218621 PPAR_gamma
ZINC49785590 agonist Compound 7a EC50 = 5.35 µM PMID: 19928766 PPAR_gamma
ZINC49792756 agonist Compound 8b EC50 = 0.84 µM PMID: 19928766 PPAR_gamma
ZINC49792841 agonist Compound 10 EC50 = 600 nM PMID: 20452212
ZINC49793579 agonist Compound 2v EC50 = 51 nM PMID: 20356736 PPAR_gamma
ZINC49802655 agonist Compound 14 IC50 = 708 nM EC50 = 101 nM PMID: 20218621 PPAR_gamma
ZINC49803057 agonist Compound 20 IC50 = 1324 nM EC50 = 10.0 nM PMID: 20218621 PPAR_gamma
ZINC49888670 agonist Compound 19 Ki = 0.96 µM EC50 = 3.9 µM PMID: 19464171
PPAR_beta
ZINC59672404 agonist Compound 23 EC50 = 500 nM PMID: 19275963 PPAR_gamma
ZINC60325686 agonist Compound 25 EC50 = 500 nM PMID: 19275963
PPAR_beta
ZINC64251890 agonist Compound 27 EC50 = 4000 nM PMID: 21344906 PPAR_beta
ZINC64466848 agonist Compound 28 EC50 = 4200 nM PMID: 21344906 PPAR_beta
ZINC66099417 agonist Compound 12c EC50 = 0.12 +/- 0.01 µM PMID: 21215640
PPAR_beta
ZINC66100342 agonist Compound 6a fold induction = 10.79 PMID: 21195611
PPAR_beta
ZINC66100345 agonist Compound 6b fold induction = 10.81 PMID: 21195611
PPAR_beta
ZINC66100380 agonist Compound 6c fold induction = 15.04 PMID: 21195611 PPAR_gamma
ZINC66100383 agonist Compound 6d fold induction = 3.61 PMID: 21195611
PPAR_beta
ZINC66100386 agonist Compound 6e fold induction = 1.37 PMID: 21195611 PPAR_beta
ZINC66100388 agonist Compound 6f fold induction = 10.49 PMID: 21195611
PPAR_beta
ZINC66100753 agonist Compound (R)-19 EC50 = 1.25 µM PMID: 21094606 PPAR_beta
ZINC66100864 agonist Compound 6g fold induction = 5.79 PMID: 21195611
PPAR_beta
ZINC66101611 agonist Compound 12a EC50 = 0.008 +/- 0.002 µM PMID: 21215640
PPAR_beta
ZINC66112736 agonist Compound (S)-18 EC50 = 2.5 µM PMID: 21094606 PPAR_beta
ZINC66166629 agonist Compound 18a EC50 = 0.15 +/- 0.01 µM PMID: 21215640
PPAR_beta
ZINC66251343 agonist Compound 6h fold induction = 3.48 PMID: 21195611
PPAR_beta
ZINC66251537 agonist Compound 6i fold induction = 1.63 PMID: 21195611
PPAR_beta
ZINC66251538 agonist Compound 6j fold induction = 1.76 PMID: 21195611 PPAR_gamma
ZINC66251665 agonist Compound 10m EC50 = 3.7 µM PMID: 21130649 PPAR_gamma
ZINC66259488 agonist Compound 12f EC50 = 1.6 +/- 0.21 µM PMID: 21215640
PPAR_beta
ZINC66259489 agonist Compound 17a EC50 = 0.5 +/- 0.03 µM PMID: 21215640
PPAR_beta
ZINC66259818 agonist Compound 10s EC50 = 1.8 µM PMID: 21130649 PPAR_gamma
ZINC66260032 agonist Compound 10b EC50 = 21 µM PMID: 21130649 PPAR_gamma
ZINC66262036 agonist Compound 6k fold induction = 2.36 PMID: 21195611
PPAR_beta
ZINC71295268 agonist Compound 32 IC50 = 2 nM EC50 = 1 nM PMID: 16384704
ZINC71296475 agonist Compound 6b EC50 = 3.6 µM PMID: 21377875 PPAR_gamma
ZINC71296990 agonist Compound 9 EC50 = 2.4 µM PMID: 21377875 PPAR_gamma
ZINC71316395 agonist Compound 6a EC50 = 0.62 µM PMID: 21377875 PPAR_gamma
ZINC71318138 agonist Compound 6d EC50 = 3.6 µM PMID: 21377875 PPAR_gamma
ZINC71329589 agonist Compound 6c EC50 = 3.6 µM PMID: 21377875 PPAR_gamma
ZINC71331069 agonist Compound 5 EC50 = 0.20 µM PMID: 21515063
PPAR_beta
ZINC71331954 agonist Compound 14b EC50 = 15 +/- 3.0 nM PMID: 21530275 PPAR_beta
ZINC71332043 agonist Compound 12 EC50 = 2.3 µM PMID: 21515063
PPAR_beta
ZINC71334180 agonist Compound 16 EC50 = 3.3 µM PMID: 21515063
PPAR_beta
ZINC71340511 agonist Compound 13 EC50 = 10.4 µM PMID: 21515063
PPAR_beta
ZINC71340668 agonist Compound 10 EC50 = 34.1 µM PMID: 21515063
PPAR_beta
ZINC71340789 agonist Compound 14c EC50 = 29 +/- 2.3 nM PMID: 21530275 PPAR_beta
ZINC71340970 agonist Compound 18 EC50 = 0.83 µM PMID: 21515063
PPAR_beta
ZINC71341094 agonist Compound 15 EC50 = 2.9 µM PMID: 21515063
PPAR_beta
ZINC72118008 agonist Compound 20 EC50 = 109.3 +/- 3.0 µM PMID: 21889235
ZINC72118009 agonist Compound 35 EC50 = 61.5 +/- 2.2 µM PMID: 21889235
ZINC72118010 agonist Compound 21 EC50 = 27.1 +/- 0.3 µM PMID: 21889235
ZINC72118206 agonist Compound 19 EC50 = 18.8 +/- 1.2 µM PMID: 21889235
ZINC72118207 agonist Compound 34 EC50 = 1.0 +/- 0.02 µM PMID: 21889235
ZINC72118646 agonist Compound 38 EC50 = 43.7 +/- 0.4 µM PMID: 21889235
ZINC72119873 agonist Compound 17 EC50 = 11.3 +/- 1.1  µM PMID: 21889235
ZINC72119874 agonist Compound 32 EC50 = 3.6 +/- 0.6 µM PMID: 21889235
ZINC72119945 agonist Compound 23 EC50 = 9.3 +/- 0.9 µM PMID: 21889235
ZINC73221647 agonist Compound 16a EC50 = 0.10 µM PMID: 22197396
ZINC73294674 agonist Compound 3 EC50 = 24.8 +/- 4.5 µM PMID: 22341573 PPAR_gamma
ZINC73295120 agonist Compound 7 EC50 = 9.8 +/- 0.5 µM PMID: 22341573 PPAR_gamma
ZINC73295126 agonist Compound 9 EC50 = 2.2 +/- 0.6 µM PMID: 22341573 PPAR_gamma
ZINC73311164 agonist Compound S-10 EC50 = 1.0 +/- 0.2 µM PMID: 22341573 PPAR_gamma