Compound ID Pharmacological profile Compound name Binding data Activity data Bibliographic ref. Cross-reactivity
CHEMBL1084360 antagonist Compound 20b pIC50 = 8.0 nM pIC50 = 5.8 PMID: 20469868
CHEMBL1254079 agonist Compound 33 IC50 = 10 nM IC50 = 38 nM PMID: 20735001
CHEMBL1254080 agonist Compound 35 IC50 = 12 nM IC50 = 40 nM PMID: 20735001
CHEMBL1254265 agonist Compound 38 IC50 = 11 nM IC50 = 15 nM PMID: 20735001
CHEMBL1254345 agonist Compound 41 IC50 = 19 nM IC50 = 21 nM PMID: 20735001
CHEMBL1254651 agonist Compound 1 IC50 = 6.6 nM PMID: 20735001
CHEMBL1254907 agonist Compound 12 IC50 = 7.1 nM IC50 = 35 nM PMID: 20735001
CHEMBL1254994 agonist Compound 13 IC50 = 2.0 nM IC50 = 2.8 nM PMID: 20735001
CHEMBL1257221 agonist Compound 4 pIC50 = 8.0 PMID: 20727743
CHEMBL1257342 agonist Compound 6 pIC50 = 7.8 PMID: 20727743
CHEMBL1257343 agonist Compound 7 pIC50 = 7.7 PMID: 20727743
CHEMBL1257453 agonist Compound 8 pIC50 = 9.0 PMID: 20727743
CHEMBL1257454 agonist Compound 9 pIC50 = 9.2 PMID: 20727743
CHEMBL1257572 agonist Compound 10 pIC50 = 8.2 PMID: 20727743
CHEMBL134260 antagonist Compound 3 Ki = 8.4 nM IC50 = 73 +/- 14 nM PMID: 18513967 MR
CHEMBL137890 agonist Compound 19 Ki = 9.0 +/- 1.9 nM EC50 = 400 +/- 21 nM PMID: 11728194
CHEMBL137982 agonist Compound 29 Ki = 9.5 +/- 4.2 nM EC50 = 223 +/- 38 nM PMID: 11728194
CHEMBL138003 agonist Compound 16 Ki = 25 +/- 14 nM EC50 = 320 +/- 170 nM PMID: 11728194
CHEMBL138098 agonist Compound 35 Ki = 2.7 +/- 0.58 nM EC50 = 34 +/- 18 nM PMID: 11728194
CHEMBL138197 agonist Compound 15 Ki = 18 +/- 0.16 nM EC50 = 460 +/- 39 nM PMID: 11728194
CHEMBL140336 agonist Compound 30 Ki = 3.7 +/- 1.2 nM EC50 = 405 +/- 44 nM PMID: 11728194
CHEMBL141282 agonist Compound 27 Ki = 9.0 +/- 4.7 nM EC50 = 146 +/- 9.9 nM PMID: 11728194
CHEMBL141344 agonist Compound 26 Ki = 14 +/- 2.5 nM EC50 = 264 +/- 1.3 nM PMID: 11728194
CHEMBL141426 agonist Compound 24 Ki = 62 +/- 10 nM EC50 = 520 nM PMID: 11728194
CHEMBL141915 agonist Compound 34 Ki = 8.1 +/- 0.04 nM EC50 = 78 +/- 15 nM PMID: 11728194
CHEMBL149744 agonist Compound 3 RBA = 183 +/- 65 % RSA = 255 +/- 153 % PMID: 12431067
CHEMBL150080 agonist Compound 18b RBA = 93 +/- 31 % RSA = 121 +/- 51 % PMID: 12431067
CHEMBL150367 agonist Compound 18a RBA = 304 +/- 167 % RSA = 436 +/- 160 % PMID: 12431067
CHEMBL1644754 agonist Compound 7 Ki = 5.8 +/- 0.7 nM EC50 = 235 +/- 25 nM PMID: 21115247
CHEMBL1644755 agonist Compound 8 Ki = 4.5 +/- 2.2 nM EC50 = 95 +/- 13 nM PMID: 21115247
CHEMBL1644756 agonist Compound 9 Ki = 3.5 +/- 0.7 nM EC50 = 7.4 +/- 0.5 nM PMID: 21115247
CHEMBL1644757 agonist Compound 10 Ki = 6.0 +/- 1.4 nM EC50 = 215 +/- 40 nM PMID: 21115247
CHEMBL1644759 agonist Compound 12 Ki = 1.7 +/- 0.4 nM EC50 = 7.4 +/- 4.5 nM PMID: 21115247
CHEMBL1644761 agonist Compound 13 Ki = 16 +/- 4 nM EC50 = 105 +/- 14 nM PMID: 21115247
CHEMBL1644765 agonist Compound 22 Ki = 10 +/- 3 nM EC50 = 370 +/- 35 nM PMID: 21115247
CHEMBL1760023 agonist Compound 26 Ki = 3.8 nM  EC50 = 3.9 +/- 0.9 nM PMID: 21324689
CHEMBL1762210 agonist Compound 27 Ki = 0.6 nM  EC50 = 1.5 +/- 0.2 nM PMID: 21324689
CHEMBL1801009 agonist Compound 16 Ki = 0.6 nM PMID: 21073190
CHEMBL1801013 agonist Compound 12 Ki = 2.5 nM PMID: 21073190
CHEMBL184508 antagonist Compound 13 IC50 = 71 nM IC50 = 290 nM PMID: 15261264
CHEMBL1911544 agonist Compound 10 IC50 = 15 nM IC50 = 36 nM PMID: 21963986
CHEMBL1911548 agonist Compound 14 IC50 = 30 nM IC50 = 6 nM PMID: 21963986
CHEMBL1911549 agonist Compound 15 IC50 = 160 nM IC50 = 290 nM PMID: 21963986
CHEMBL1911644 agonist Compound 16 IC50 = 5 nM IC50 = 8 nM PMID: 21963986
CHEMBL1911645 agonist Compound 17 IC50 = 28 nM IC50 = 88 nM PMID: 21963986
CHEMBL1911646 agonist Compound 18 IC50 = 24 nM IC50 = 78 nM PMID: 21963986
CHEMBL1911647 agonist Compound 19 IC50 = 66 nM IC50 = 113 nM PMID: 21963986
CHEMBL1911648 agonist Compound 20 IC50 = 290 nM IC50 = 191 nM PMID: 21963986
CHEMBL1911651 agonist Compound 22 IC50 = 30 nM IC50 = 29 nM PMID: 21963986
CHEMBL1911654 agonist Compound 25 IC50 = 14 nM IC50 = 14 nM PMID: 21963986
CHEMBL1911655 agonist Compound 26 IC50 = 19 nM IC50 = 10 nM PMID: 21963986
CHEMBL1911656 agonist Compound 27 IC50 = 8 nM IC50 = 21 nM PMID: 21963986
CHEMBL1911657 agonist Compound 28 IC50 = 10 nM IC50 = 7 nM PMID: 21963986
CHEMBL1911659 agonist Compound 30 IC50 = 15 nM IC50 = 104 nM PMID: 21963986
CHEMBL1911660 agonist Compound 31 IC50 = 6 nM IC50 = 100 nM PMID: 21963986
CHEMBL1911661 agonist Compound 32 IC50 = 5 nM IC50 = 49 nM PMID: 21963986
CHEMBL194802 antagonist Compound 25 IC50 = 20 +/- 8 nM % inhibition = 100 % PMID: 16112571
CHEMBL195021 antagonist Compound 4 IC50 = 370 +/- 10 nM % inhibition = 70 % PMID: 16112571
CHEMBL1950696 antagonist Compound 6b IC50 = 142 nM PMID: 22260770 PR
CHEMBL1950697 antagonist Compound 5d IC50 = 61 nM PMID: 22260770 PR
CHEMBL1950698 antagonist Compound 6a IC50 = 60 nM PMID: 22260770 PR
CHEMBL195962 antagonist Compound 27 IC50 = 8 +/- 2 nM % inhibition = 100 % PMID: 16112571
CHEMBL196051 antagonist Compound 19 IC50 = 60 +/- 1 nM % inhibition = 100 % PMID: 16112571
CHEMBL196067 antagonist Compound 2 IC50 = 79 +/- 8 nM  % inhibition = 100 % PMID: 16112571
CHEMBL196237 antagonist Compound 12 IC50 = 72 +/- 15 nM % inhibition = 90 % PMID: 16112571
CHEMBL196373 antagonist Compound 5 IC50 = 200 +/- 47 nM  % inhibition = 95 % PMID: 16112571
CHEMBL196374 agonist Compound 3 pIC50 = 8.5 PMID: 20727743
CHEMBL197100 antagonist Compound 31 IC50 = 81 +/- 6 nM % inhibition = 100 % PMID: 16112571
CHEMBL197161 antagonist Compound 10 IC50 = 13 +/- 1 nM  % inhibition = 100 % PMID: 16112571
CHEMBL2087285 antagonist Compound 8e IC50 = 722 nM IC50 = 1050 nM PMID: 22917520
CHEMBL2087288 antagonist Compound 8f IC50 = 145 nM IC50 = 46 nM PMID: 22917520
CHEMBL2087289 antagonist Compound 8g IC50 = 4.5 nM IC50 = 211 nM PMID: 22917520
CHEMBL2087290 antagonist Compound 8h IC50 = 235 nM IC50 = 512 nM PMID: 22917520
CHEMBL2087291 antagonist Compound 8i IC50 = 96 nM IC50 = 391 nM PMID: 22917520
CHEMBL2087292 antagonist Compound 8j IC50 = 801 nM IC50 = 1171 nM PMID: 22917520
CHEMBL2087293 antagonist Compound 8k IC50 = 879 nM IC50 = 1423 nM PMID: 22917520
CHEMBL2087298 antagonist Compound 8p IC50 = 298 nM IC50 = 598 nM PMID: 22917520
CHEMBL2087299 antagonist Compound 8q IC50 = 111 nM IC50 = 421 nM PMID: 22917520
CHEMBL208811 agonist Compound Ia RBA = 250 +/- 30 % RSA = 237 +/- 68 % PMID: 16644222
CHEMBL2096708 antagonist Compound 16hβ Ki = 0.17 nM (0.11 – 0.27) PMID: 15293993
CHEMBL2096804 antagonist Compound 16hα Ki = 0.21 nM (0.20 – 0.23) PMID: 15293993
CHEMBL210657 agonist Compound Ib RBA = 93 +/- 31 % RSA = 121 +/- 51 % PMID: 16644222
CHEMBL216173 agonist Compound 33 IC50 = 10 nM IC50 = 34 nM PMID: 17181172
CHEMBL216272 agonist Compound 1 pIC50 = 7.7 PMID: 20727743
CHEMBL216273 agonist Compound 14 IC50 = 10 nM IC50 = 75 nM PMID: 17181172
CHEMBL219015 agonist Compound 21 IC50 = 120 nM IC50 = 53 nM PMID: 17181172
CHEMBL219140 agonist Compound 28 IC50 = 77 nM IC50 = 56 nM PMID: 17181172
CHEMBL219207 agonist Compound 37 IC50 = 3 nM IC50 = 3 nM PMID: 17181172
CHEMBL219314 agonist Compound 24 IC50 = 4 nM IC50 = 110 nM PMID: 17181172
CHEMBL219561 agonist Compound 35 IC50 = 11 nM IC50 = 17 nM PMID: 17181172
CHEMBL219973 agonist Compound 12 IC50 = 5 nM IC50 = 6 nM PMID: 17181172
CHEMBL2204038 antagonist Compound 2 ki = 4 nM Reporter gene Ki = 44 nM PMID: 23131342
CHEMBL2204040 antagonist Compound 4 Ki = 3 nM Reporter gene Ki = 21 nM PMID: 23131342
CHEMBL2204041 antagonist Compound 5 Ki = 19 nM Reporter gene Ki = 78 nM PMID: 23131342
CHEMBL2204042 antagonist Compound 6 Ki = 7 nM Reporter gene Ki = 37 nM PMID: 23131342
CHEMBL2204043 antagonist Compound 7 Ki = 8 nM Reporter gene Ki = 24 nM PMID: 23131342
CHEMBL2204045 antagonist Compound 9 Ki = 9 nM Reporter gene Ki = 56 nM PMID: 23131342
CHEMBL2204046 antagonist Compound 10 Ki = 8 nM Reporter gene Ki = 23 nM PMID: 23131342
CHEMBL2204047 antagonist Compound 11 Ki = 5 nM Reporter gene Ki = 25 nM PMID: 23131342
CHEMBL2204048 antagonist Compound 12 Ki = 11 nM Reporter gene Ki = 44 nM PMID: 23131342
CHEMBL2204049 antagonist Compound 13 Ki = 11 nM Reporter gene Ki = 67 nM PMID: 23131342
CHEMBL2204050 antagonist Compound 14 Ki = 188 nM Reporter gene Ki = 337 nM PMID: 23131342
CHEMBL2204052 antagonist Compound 16 Ki = 49 nM Reporter gene Ki = 116 nM PMID: 23131342
CHEMBL2204055 antagonist Compound 19 Ki = 28 nM Reporter gene Ki = 119 nM PMID: 23131342
CHEMBL2204057 antagonist Compound 21 Ki = 22 nM Reporter gene Ki = 57 nM PMID: 23131342
CHEMBL2204058 antagonist Compound 22 Ki = 18 nM Reporter gene Ki = 47 nM PMID: 23131342
CHEMBL2204059 antagonist Compound 23 Ki = 21 nM Reporter gene Ki = 44 nM PMID: 23131342
CHEMBL231770 antagonist Compound 18 Ki = 7.2 +/- 1.5 nM IC50 = 2.3 +/- 1.3 nM PMID: 17553679
CHEMBL231771 antagonist Compound 20 Ki = 4.1 +/- 0.9 nM IC50 = 1.9 +/- 0.2 nM PMID: 17553679
CHEMBL231772 antagonist Compound 21 Ki = 4.6 nM IC50 = 1.9 nM (94%) PMID: 17553679
CHEMBL231974 antagonist Compound 22 Ki = 3.1 +/- 0.8 nM IC50 = 0.5 +/- 0.1 nM  PMID: 17553679
CHEMBL231975 antagonist Compound 23 Ki = 1.5 +/- 0.1 nM IC50 = 0.7 +/- 0.1 nM PMID: 17553679
CHEMBL232760 antagonist Compound 16 Ki = 2.5 +/- 0.5 nM IC50 = 0.2 +/- 0.1 nM PMID: 17553679
CHEMBL232761 antagonist Compound 17 Ki = 2.7 +/- 0.1 nM IC50 = 2.5 +/- 1.2 nM PMID: 17553679
CHEMBL235063 agonist Compound 36 IC50 = 17 nM IC50 = 20 nM PMID: 17692519
CHEMBL236755 agonist Compound 40 IC50 = 11 nM IC50 = 4 nM PMID: 17692519
CHEMBL242690 antagonist Compound 24 PMID: 17070047
CHEMBL243455 agonist Compound 6 EC50 = 0.3 +/- 0.1 nM PMID: 17705362
CHEMBL243656 antagonist Compound 15 Ki = 1.4 +/- 0.2 nM EC50 = 0.3 +/- 0.1 nM PMID: 17705362
CHEMBL243657 antagonist Compound 17 EC50 = 0.4 +/- 0.3 nM PMID: 17705362
CHEMBL244535 agonist Compound 18 EC50 = 0.6 +/- 0.3 nM PMID: 17705362
CHEMBL244537 antagonist Compound 20 Ki = 1.2 nM EC50 = 1.3 +/- 0.9 nM PMID: 17705362
CHEMBL244713 antagonist Compound 21 EC50 = 0.6 +/- 0.3 nM PMID: 17705362
CHEMBL244715 agonist Compound 27 EC50 = 1.4 +/- 0.3 nM PMID: 17705362
CHEMBL246834 antagonist Compound 57 Ki = 2 nM GR functional Ki = 180 nM PMID: 17822897
CHEMBL247006 antagonist Compound 59 Ki = 10 nM GR functional Ki = 400 nM PMID: 17822897
CHEMBL247632 antagonist Compound 49 Ki = 9 nM GR functional Ki = 200 nM PMID: 17822897
CHEMBL248027 antagonist Compound 56 Ki = 13 nM GR functional Ki = 323 nM PMID: 17822897
CHEMBL253745 agonist Compound 20 Ki = 1400 +/- 100 nM EC50 = 48 +/- 13 nM PMID: 18513967
CHEMBL255369 antagonist Compound 42 Ki = 0.5 nM GR functional Ki = 5.7 nM PMID: 18226897
CHEMBL255370 antagonist Compound 43 Ki = 1.4 nM GR functional Ki = 33 nM PMID: 18226897
CHEMBL255521 antagonist Compound 31 Ki = 9 nM GR functional Ki = 293 nM PMID: 18226897
CHEMBL255843 antagonist Compound 65 Ki = 2.6 nM GR functional Ki = 29 nM PMID: 18226897
CHEMBL255950 antagonist Compound 66 Ki = 1.2 nM GR functional Ki = 6.9 nM PMID: 18226897
CHEMBL256787 agonist Compound 13 Ki = 22 nM EC50 = 7.5 +/- 1.6 nM PMID: 18513967
CHEMBL256894 antagonist Compound 72 Ki = 1.5 nM GR functional Ki = 4.9 nM PMID: 18226897
CHEMBL257079 antagonist Compound 13 Ki = 4.5 nM GR functional Ki = 343 nM PMID: 18226897
CHEMBL257152 agonist Compound 17 Ki = 75 +/- 18 nM EC50 = 46 +/- 9 nM PMID: 18513967
CHEMBL257203 antagonist Compound 64 Ki = 1.1 nM GR functional Ki = 10 nM PMID: 18226897
CHEMBL257204 antagonist Compound 62 Ki = 2.1 nM GR functional Ki = 17 nM PMID: 18226897
CHEMBL257461 antagonist Compound 77 Ki = 0.6 nM GR functional Ki = 18 nM PMID: 18226897
CHEMBL257462 antagonist Compound 76 Ki = 1.6 nM GR functional Ki = 5.8 nM PMID: 18226897
CHEMBL258191 agonist Compound 9 Ki = 13 +/- 1 nM EC50 = 20 +/- 3 nM PMID: 18513967
CHEMBL263091 agonist Compound 2 pIC50 = 9.0 PMID: 20727743
CHEMBL263942 antagonist Compound 19aα Ki = 1.1 nM (1.1 – 1.2) PMID: 15293993
CHEMBL265125 antagonist Compound 16kβ Ki = 0.22 nM (0.20 – 0.25) PMID: 15293993
CHEMBL266282 agonist Compound 18 Ki = 2.5 +/- 0.46 nM EC50 = 33 +/- 8.0 nM PMID: 11728194
CHEMBL266656 antagonist Compound 20α Ki = 6.5 nM (4.8 – 8.2) PMID: 15293993
CHEMBL266673 antagonist Compound 16jβ Ki = 0.18 nM (0.17 – 0.20) PMID: 15293993
CHEMBL266935 antagonist Compound 16bα Ki = 0.39 nM (0.35-0.43) PMID: 15293993
CHEMBL270143 antagonist Compound 69 Ki = 1.0 nM GR functional Ki = 3.1 nM PMID: 18226897
CHEMBL270568 antagonist Compound 53 Ki = 0.8 nM GR functional Ki = 8.7 nM PMID: 18226897
CHEMBL270575 antagonist Compound 52 Ki = 0.7 nM GR functional Ki = 0.6 nM PMID: 18226897
CHEMBL270588 antagonist Compound 6 Ki = 1.3 nM GR functional Ki = 14 nM PMID: 18226897
CHEMBL270667 antagonist Compound 49 Ki = 0.5 nM GR functional Ki = 2.9 nM PMID: 18226897
CHEMBL270668 antagonist Compound 50 Ki = 0.3 nM GR functional Ki = 1.2 nM PMID: 18226897
CHEMBL270838 antagonist Compound 78 Ki = 0.9 nM GR functional Ki = 7.1 nM PMID: 18226897
CHEMBL270839 antagonist Compound 39 Ki = 1.6 nM GR functional Ki = 47 nM PMID: 18226897
CHEMBL270879 antagonist Compound 48 Ki = 0.9 nM GR functional Ki = 9.0 nM PMID: 18226897
CHEMBL271019 antagonist Compound 7 Ki = 2.2 nM GR functional Ki = 36 nM PMID: 18226897
CHEMBL271054 antagonist Compound 40 Ki = 8.6 nM GR functional Ki = 184 nM PMID: 18226897
CHEMBL271220 antagonist Compound 47 Ki = 0.9 nM GR functional Ki = 6.8 nM PMID: 18226897
CHEMBL271221 antagonist Compound 46 Ki = 0.8 nM GR functional Ki = 1.9 nM PMID: 18226897
CHEMBL271263 antagonist Compound 17 Ki = 2.5 nM GR functional Ki = 245 nM PMID: 18226897
CHEMBL271428 antagonist Compound 45 Ki = 0.8 nM GR functional Ki = 28 nM PMID: 18226897
CHEMBL272788 antagonist Compound 9 Ki = 1.4 nM GR functional Ki = 26 nM PMID: 18226897
CHEMBL272789 antagonist Compound 29 Ki = 1.2 nM GR functional Ki = 53 nM PMID: 18226897
CHEMBL272923 antagonist Compound 68 Ki = 2.8 nM GR functional Ki = 28 nM PMID: 18226897
CHEMBL273141 antagonist Compound 28 Ki = 2.3 nM GR functional Ki = 96 nM PMID: 18226897
CHEMBL273143 antagonist Compound 56 Ki = 12 nM GR functional Ki = 201 nM PMID: 18226897
CHEMBL292721 antagonist Compound 16 IC50 = 1937 nM (1273-2947) IC50 = 2017 nM PMID: 15080982
CHEMBL293388 antagonist Compound 19l IC50 = 7 nM (6-8) IC50 = 66 nM PMID: 15080982
CHEMBL293452 antagonist Compound 19e IC50 = 2 nM IC50 = 78 nM PMID: 15080982
CHEMBL294800 antagonist Compound 19c IC50 = 1 nM IC50 = 21 nM PMID: 15080982
CHEMBL302147 antagonist Compound 17h IC50 = 404 nM (294-554) IC50 = 289 nM PMID: 15080982
CHEMBL302442 antagonist Compound 19p IC50 = 31 nM (28-34) IC50 = 296 nM PMID: 15080982
CHEMBL303071 antagonist Compound 19v IC50 = 47 nM (43-50) IC50 = 630 nM PMID: 15080982
CHEMBL303813 antagonist Compound 10 IC50 = 892 nM (559-1423) IC50 = 1805 nM PMID: 15080982
CHEMBL304019 antagonist Compound 19i IC50 = 10 nM (9-12) IC50 = 129 nM PMID: 15080982
CHEMBL304258 antagonist Compound 17g IC50 = 160 nM (159-161) IC50 = 124 nM PMID: 15080982
CHEMBL304482 antagonist Compound 19b IC50 = 6 nM (5-6) IC50 = 122 nM PMID: 15080982
CHEMBL304877 antagonist Compound 19j IC50 = 3 nM (3-4) IC50 = 378 nM PMID: 15080982
CHEMBL305393 antagonist Compound 17j IC50 = 910 nM (838-988) IC50 = 402 nM PMID: 15080982
CHEMBL336041 agonist Compound 28 Ki = 5.0 +/- 2.2 nM EC50 = 75 +/- 0.40 nM PMID: 11728194
CHEMBL337112 agonist Compound 32 Ki = 2.1 +/- 0.01 nM EC50 = 38 +/-10 nM PMID: 11728194
CHEMBL363137 antagonist Compound 6 IC50 = 9 +/- 3 nM  % inhibition = 100 % PMID: 16112571
CHEMBL364368 antagonist Compound 3 Ki = 0.4 nM (0.24 – 0.66) PMID: 15293993
CHEMBL372102 antagonist Compound 29 IC50 = 7 +/- 1 nM % inhibition = 100 % PMID: 16112571
CHEMBL373497 agonist Compound 38 IC50 = 4 nM IC50 = 11 nM PMID: 17181172
CHEMBL374507 antagonist Compound 4a IC50 = 3.1 nM IC50 = 30.7 nM PMID: 16987661
CHEMBL374732 antagonist Compound 4b IC50 = 4.9 nM IC50 = 200 nM PMID: 16987661
CHEMBL375348 agonist Compound 20 IC50 = 38 nM IC50 = 270 nM PMID: 17181172
CHEMBL375838 agonist Compound 31 IC50 = 6 nM IC50 = 6 nM PMID: 17181172
CHEMBL384081 agonist Compound 34 IC50 = 8 nM IC50 = 5.6 nM PMID: 17181172
CHEMBL384444 antagonist Compound 4c IC50 = 2.5 nM IC50 = 23.5 nM PMID: 16987661
CHEMBL384975 antagonist Compound 16eα Ki = 0.27 nM (0.16 – 0.46) PMID: 15293993
CHEMBL386465 agonist Compound 11 IC50 = 10 nM IC50 = 21 nM PMID: 17181172
CHEMBL386916 agonist Compound 29 IC50 = 34 nM IC50 = 35 nM PMID: 17181172
CHEMBL388018 antagonist Compound 12 Ki = 0.9 nM Ki (hGRAF) = 33 nM PMID: 17070047
CHEMBL391458 agonist Compound 24 Ki = 1.7 nM EC50 = 43 +/- 8.5 nM PMID: 17553679
CHEMBL392499 agonist Compound 33 IC50 = 46 nM IC50 = 125 nM PMID: 17692519
CHEMBL392500 agonist Compound 38 IC50 = 21 nM IC50 = 70 nM PMID: 17692519
CHEMBL392501 agonist Compound 41 IC50 = 8 nM IC50 = 40 nM PMID: 17692519
CHEMBL401013 antagonist Compound 47 Ki = 6 nM GR functional Ki = 230 nM PMID: 17822897
CHEMBL401864 antagonist Compound 63 Ki = 0.9 nM GR functional Ki = 11 nM PMID: 18226897
CHEMBL402351 antagonist Compound 10 Ki = 1.3 nM GR functional Ki = 11 nM PMID: 18226897
CHEMBL402893 antagonist Compound 44 Ki = 0.8 nM GR functional Ki = 7.7 nM PMID: 18226897
CHEMBL403172 antagonist Compound 41 Ki = 1.0 nM GR functional Ki = 20 nM PMID: 18226897
CHEMBL403173 antagonist Compound 18 Ki = 18 nM GR functional Ki = 390 nM PMID: 18226897
CHEMBL403178 antagonist Compound 15 Ki = 3 nM GR functional Ki = 68 nM PMID: 18226897
CHEMBL403179 antagonist Compound 71 Ki = 1.4 nM GR functional Ki = 11 nM PMID: 18226897
CHEMBL403274 agonist Compound 18 Ki = 15 nM EC50 = 9.2 +/- 3.4 nM PMID: 18513967
CHEMBL403334 antagonist Compound 79 Ki = 6.7 nM GR functional Ki = 85 nM PMID: 18226897
CHEMBL403761 antagonist Compound 67 Ki = 1.7 nM GR functional Ki = 14 nM PMID: 18226897
CHEMBL403921 antagonist Compound 8 Ki = 1.5 nM GR functional Ki = 17 nM PMID: 18226897
CHEMBL403966 antagonist Compound 57 Ki = 8.6 nM GR functional Ki = 77 nM PMID: 18226897
CHEMBL404160 antagonist Compound 61 Ki = 2.4 nM GR functional Ki = 16 nM PMID: 18226897
CHEMBL404183 antagonist Compound 54 Ki = 0.8 nM GR functional Ki = 1.6 nM PMID: 18226897
CHEMBL404192 antagonist Compound 16 Ki = 15 nM GR functional Ki = 438 nM PMID: 18226897
CHEMBL404496 antagonist Compound 7 Ki = 450 nM IC50 = 10 +/- 2 nM PMID: 18513967
CHEMBL404640 antagonist Compound 14 Ki = 6600 nM IC50 = 67 +/- 20 nM PMID: 18513967
CHEMBL404879 antagonist Compound 15 Ki = 520 nM IC50 = 12 +/- 4 nM PMID: 18513967
CHEMBL406027 antagonist Compound 16fα Ki = 0.30 nM (0.27 – 0.33) PMID: 15293993
CHEMBL406064 antagonist Compound 16iβ Ki = 0.16 (0.14 – 0.19) PMID: 15293993
CHEMBL407672 antagonist Compound 21bβ Ki = 0.27 nM (0.17 – 0.38) PMID: 15293993
CHEMBL408376 antagonist Compound 16dα Ki = 0.27 nM (0.1 – 1.5) PMID: 15293993
CHEMBL409123 antagonist Compound 17β Ki = 0.11 nM (0.06 – 0.16) PMID: 15293993
CHEMBL409835 antagonist Compound 75 Ki = 0.8 nM GR functional Ki = 5.8 nM PMID: 18226897
CHEMBL410037 antagonist Compound 73 Ki = 1.6 nM GR functional Ki = 8.0 nM PMID: 18226897
CHEMBL410683 antagonist Z-guggulsterone Ki = 252 +/- 2 nM IC50 = 6060 +/- 310 nM PMID: 16250653
PR
CHEMBL411185 antagonist Compound 16aα Ki = 2.1 nM (1.8-2.8) PMID: 15293993
CHEMBL411457 antagonist Compound 33 Ki = 3.4 nM GR functional Ki = 78 nM PMID: 18226897
CHEMBL411852 antagonist Compound 55 Ki = 0.8 nM GR functional Ki = 5.1 nM PMID: 18226897
CHEMBL413806 antagonist Compound 5c IC50 = 59.8 nM PMID: 17258455
CHEMBL414041 antagonist Compound 19bα Ki = 1.2 nM (0.87 – 1.7 nM) PMID: 15293993
CHEMBL414318 antagonist Compound 21aβ Ki = 0.42 nM (0.42 – 0.43) PMID: 15293993
CHEMBL415099 antagonist Compound 32 Ki = 3.7 nM GR functional Ki = 178 nM PMID: 18226897
CHEMBL415621 antagonist Compound 16gβ Ki = 0.42 nM (0.32 – 0.61) PMID: 15293993
CHEMBL416869 antagonist Compound 17f IC50 = 117 nM (106-131) IC50 = 69 nM PMID: 15080982
CHEMBL417202 antagonist Compound 19u IC50 = 23 nM IC50 = 180 nM PMID: 15080982
CHEMBL422857 agonist Compound 4 RBA = 86 +/- 50 % RSA = 135 +/- 87 % PMID: 12431067
CHEMBL425970 agonist Compound 32 IC50 = 22 nM IC50 = 61 nM PMID: 17181172
CHEMBL427568 antagonist Compound 16cα Ki = 0.67 nM (0.3 – 1.4) PMID: 15293993
CHEMBL427899 agonist Compound 11 Ki = 650 nM EC50 = 191 +/- 70 nM PMID: 18513967
CHEMBL429842 agonist Compound 19 Ki = 151 +/- 30 nM EC50 = 76 +/- 11 nM PMID: 18513967
CHEMBL429913 antagonist Compound 74 Ki = 1.1 nM GR functional Ki = 3.4 nM PMID: 18226897
CHEMBL435433 agonist Compound 16b RBA = 166 +/- 47 % RSA = 97 +/- 59 % PMID: 12431067
CHEMBL436859 antagonist Compound 15 Ki = 3.0 nM (1.0 – 6.3) PMID: 15293993
CHEMBL437556 agonist Compound 28 Ki = 4.4 nM EC50 = 33 nM PMID: 17553679
CHEMBL438386 antagonist Compound 70 Ki = 3.8 nM GR functional Ki = 60 nM PMID: 18226897
CHEMBL438885 antagonist Compound 16 Ki = 650 nM IC50 = 53 +/- 12 nM PMID: 18513967
CHEMBL440251 antagonist Compound 18β Ki = 0.80 nM (0.7-0.9) PMID: 15293993
CHEMBL442803 antagonist Compound 51 Ki = 0.6 nM GR functional Ki = 5.2 nM PMID: 18226897
CHEMBL464245 agonist Compound 16d pIC50 = 7.7 pEC50 = 7.3 PMID: 19019676
CHEMBL464907 agonist Compound 16b pIC50 = 7.1 pEC50 = 6.6 PMID: 19019676
CHEMBL465927 agonist Compound 16c pIC50 = 7.8 pEC50 = 7.6 PMID: 19019676
CHEMBL481185 agonist Compound 13a pIC50 = 7.3 pEC50 = 7.3 PMID: 19019676
CHEMBL481784 agonist Compound 14a pIC50 = 7.4 pEC50 = 6.1 PMID: 19019676
CHEMBL489788 antagonist Compound 13 IC50 = 120 nM PMID: 18722119 PR
CHEMBL516033 agonist Compound 13j pIC50 = 7.3 pEC50 = 7.6 PMID: 19019676
CHEMBL518451 agonist Compound 13o pIC50 = 8.2 pEC50 = 7.3 PMID: 19019676
CHEMBL519947 agonist Compound 13k pIC50 = 7.8 pEC50 = 6.6 PMID: 19019676
CHEMBL520750 agonist Compound 13l pIC50 = 8.1 pEC50 = 7.3 PMID: 19019676
CHEMBL522432 antagonist Compound 12 IC50 = 127 nM PMID: 18722119 PR
CHEMBL550258 agonist Compound 36 pIC50 = 9.3 +/- 0.4 PMID: 19592247
CHEMBL550730 agonist Compound 32 pIC50 = 9.7 +/- 0.2 PMID: 19592247
CHEMBL550933 agonist Compound 34 pIC50 = 9.5 +/- 0.2 PMID: 19592247
CHEMBL551816 agonist Compound 38 pIC50 = 9.9 +/- 0.2 PMID: 19592247
CHEMBL556231 agonist Compound 37 pIC50 = 9.5 +/- 0.3 PMID: 19592247
CHEMBL558716 agonist Compound 26 pIC50 = 8.5 +/- 0.1 PMID: 19592247
CHEMBL559115 agonist Compound 30 pIC50 = 9.5 +/- 0.2 PMID: 19592247
CHEMBL559546 agonist Compound 23 pIC50 = 8.1 +/ -0.1 PMID: 19592247
CHEMBL559547 agonist Compound 6 pIC50 = 8.6 +/- 0.4 PMID: 19592247
CHEMBL559742 agonist Compound 25 pIC50 = 8.3 +/- 0.2 PMID: 19592247
CHEMBL559942 agonist Compound 27 pIC50 = 9.4 +/- 0.2 PMID: 19592247
CHEMBL560797 agonist Compound 31 pIC50 = 9.6 +/- 0.3 PMID: 19592247
CHEMBL561276 agonist Compound 28 pIC50 = 9.1 +/- 0.2 PMID: 19592247
CHEMBL561475 agonist Compound 29 pIC50 = 9.4 +/- 0.3 PMID: 19592247
CHEMBL562337 agonist Compound 13 pIC50 = 7.6 +/- 0.1 PMID: 19592247
CHEMBL563595 agonist Compound 24 pIC50 = 9.1 +/- 0.3 PMID: 19592247
CHEMBL563812 agonist Compound 35 pIC50 = 9.6 +/- 0.3 PMID: 19592247
CHEMBL564160 agonist Compound 33 pIC50 = 9.7 +/- 0.4 PMID: 19592247
CHEMBL564332 agonist Compound 7 pIC50 = 7.5 +/- 0.1 PMID: 19592247
CHEMBL62118 antagonist Compound 17c IC50 = 41 nM (26-67) IC50 = 121 nM PMID: 15080982
CHEMBL62981 antagonist Compound 15 IC50 = 324 nM PMID: 12781197 PR
CHEMBL63422 antagonist Compound 20 IC50 = 10000 nM IC50 = 1914 nM PMID: 15080982
CHEMBL63431 antagonist Compound 19a IC50 = 812 nM (681-974) IC50 = 665 nM PMID: 15080982
CHEMBL63932 antagonist Compound 19q IC50 = 61 nM (39-94) IC50 = 388 nM PMID: 15080982
CHEMBL64095 antagonist Compound 19o IC50 = 63 nM IC50 = 847 nM PMID: 15080982
CHEMBL65021 antagonist Compound 11a IC50 = 19 nM (17-21) IC50 = 87 nM PMID: 15080982
CHEMBL65074 antagonist Compound 17a IC50 = 1053 nM (949-1169) IC50 = 210 nM PMID: 15080982
CHEMBL65221 antagonist Compound 11c IC50 = 2 nM (2-2) IC50 = 57 nM PMID: 15080982
CHEMBL65354 antagonist Compound 19f IC50 = 3 nM (3-4) IC50 = 76 nM PMID: 15080982
CHEMBL65381 antagonist Compound 17i IC50 = 564 nM (379-840) IC50 = 382 nM PMID: 15080982
CHEMBL65444 antagonist Compound 17b IC50 = 62 nM (61-63) IC50 = 251 nM PMID: 15080982
CHEMBL65469 antagonist Compound 17e IC50 = 146 nM (133-161) IC50 = 137 nM PMID: 15080982
CHEMBL65498 antagonist Compound 19m IC50 = 11 nM (10-12) IC50 = 43 nM PMID: 15080982
CHEMBL65570 antagonist Compound 17d IC50 = 18 nM (13-26) IC50 = 93 nM PMID: 15080982
CHEMBL65690 antagonist Compound 10 IC50 = 177 +/- 68 nM PMID: 12781197 PR
CHEMBL65695 antagonist Compound 19h IC50 = 3 nM (3-3) IC50 = 147 nM PMID: 15080982
CHEMBL65929 antagonist Compound 18 IC50 = 146 +/- 77 nM PMID: 12781197
MR
CHEMBL66582 antagonist Compound 19n IC50 = 48 nM (44-53) IC50 = 434 nM PMID: 15080982
CHEMBL66598 antagonist Compound 11b IC50 = 81 nM (70-92) IC50 = 308 nM PMID: 15080982
CHEMBL72866 antagonist Compound 10b RBA = 84 % Bioorg. Med. Chem. Lett., 1997, 7, 17, 2229
CHEMBL78124 antagonist Compound 14 IC50 = 16.7 nM IC50 = 2.8 µM PMID: 12824023
CHEMBL97206 agonist Compound 5 Ki = 4.0 +/- 0.84 nM EC50 = 9.0 +/- 0.97 nM PMID: 11728194
ZINC00005954 agonist Compound 8 EC150 = 5.5 µM PMID: 19592245
ZINC00018056 agonist Compound 14 EC150 = 21.9 µM PMID: 19592245
ZINC00057674 agonist Compound 5 EC150 = 26.1 µM PMID: 19592245
ZINC00057676 agonist Compound 7 EC150 = 6.0 µM PMID: 19592245
ZINC00057677 agonist Compound 9 EC150 = 7.1 µM PMID: 19592245
ZINC00057681 agonist Compound 16 EC150 = 10.3 µM PMID: 19592245
ZINC00057751 agonist Compound 11 EC150 = 0.7 µM PMID: 19592245
ZINC00058093 agonist Compound 12 EC150 = 12.6 µM PMID: 19592245
ZINC00058123 agonist Compound 10 EC150 = 3.6 µM PMID: 19592245
ZINC01546562 agonist Compound 15 Ki = 533 +/- 304 nM PMID: 9873735
ZINC02003450 antagonist Compound 3 Ki = 210 nM PMID: 9667968
ZINC02007389 agonist Compound 10 Ki = 4.7 +/- 0.7 nM IC50 = 123 +/- 40 nM PMID: 11520196
ZINC02558152 agonist Compound 1 RLA = 1.45 +/- 0.093 PMID: 17067160
ZINC03814363 antagonist cyproterone acetate Kd = 45 nM PMID: 12695529 PR
ZINC03814382 antagonist mifepristone PMID: 2864478
AR
ZINC03831128 antagonist RU-486 Ki = 0.24 +/- 0.02 nM Kif = 2.0 +/- 0.7 nM PMID: 12036351
MR
ZINC03831936 agonist Compound 22 EC50 = 350-500 nM PMID: 9464361
ZINC03831945 antagonist Compound 19 Ki = 34 +/- 4 nM IC50 = 266 +/- 103 nM PMID: 9464360 
ZINC03831946 antagonist Compound 26 Ki = 39 +/- 8 nM IC50 = 171 +/- 39 nM PMID: 9464360 
ZINC03831947 antagonist onapristone Ki = 41.8 +/- 4.6 nM IC50 = 27 +/- 4 nM PMID: 8627601 PR
ZINC03831948 antagonist Compound 32 Ki = 42 +/- 7 nM IC50 = 166 nM PMID: 9464360 
ZINC03831950 antagonist Compound 24 Ki = 44 +/- 12 nM IC50 = 505 +/- 320 nM PMID: 9464360 
ZINC03831954 antagonist Compound 18 Ki = 58 +/- 21 nM IC50 = 136 +/- 52 nM PMID: 9464360 
ZINC03831956 antagonist Compound 25 Ki = 59 +/- 22 nM IC50 = 80 +/- 45 nM PMID: 9464360  AR
ZINC03831957 antagonist Compound 29 Ki = 60 +/- 22 nM IC50 = 185 +/- 74 nM PMID: 9464360 
ZINC03831958 antagonist Compound 16 Ki = 67 +/- 3 nM IC50 = 115 +/- 27 nM PMID: 9464360 
ZINC03831960 antagonist Compound 22 Ki = 80 +/- 36 nM IC50 = 294 +/- 161 nM PMID: 9464360 
ZINC03831961 antagonist Compound 30 Ki = 100 +/- 16 nM IC50 = 225 +/- 84 nM PMID: 9464360 
ZINC03831964 antagonist Compound 27 Ki = 147 +/- 52 nM IC50 = 275 +/- 63 nM PMID: 9464360 
ZINC03831965 antagonist Compound 15 Ki = 152 +/- 16 nM IC50 = 339 +/- 154 nM PMID: 9464360 
ZINC03831966 antagonist Compound 13 Ki = 154 +/- 16 nM IC50 = 226 +/- 55 nM PMID: 9464360 
ZINC03831985 antagonist Compound 20 Ki = 249 +/- 157 nM PMID: 10212133
ZINC03832312 antagonist Compound 5c IC50 = 2600 +/- 200 nM PMID: 10743938 MR
ZINC03832316 antagonist Compound 6k IC50 = 780 +/- 230 nM PMID: 10743938
MR
ZINC03832322 antagonist Compound 6h IC50 = 3200 nM PMID: 10743938
ZINC03833820 agonist dexamethasone Kd = 3.7 +/- 0.6 nM EC50 = 1 nM PMID: 10611474
ZINC03833821 agonist prednisolone IC50 = 7 +/- 4 nM EC50 = 55 nM PMID: 20427184 MR
ZINC03833823 agonist deoxycorticosterone PMID: 8282004 MR
ZINC03833824 agonist aldosterone Kd = 14.4 +/- 2.1 PMID: 8282004 MR
ZINC03833825 antagonist spironolactone IC50 = 6920 nM PMID: 20672822 MR
ZINC03869768 agonist Compound 22 EC150 = 55.7 µM PMID: 19592245
ZINC03871358 agonist Compound 21 EC150 = 2.1 µM PMID: 19592245
ZINC03871576 agonist Compound 20 EC150 = 5.2 µM PMID: 19592245
ZINC03871633 agonist Compound 19 EC150 = 18.9 µM PMID: 19592245
ZINC03872070 agonist Compound 17 EC150 = 1.5 µM PMID: 19592245
ZINC03882036 agonist triamcinolone IC50 = 21.4 +/- 3.9 nM PMID: 10747884
ZINC03920027 agonist fluticasone propionate EC50 = 1.09 nM PMID: 21880489
ZINC03931014 agonist budesonide EC50 = 12.40 nM PMID: 21880489
ZINC03937474 agonist Compound 30 IC50 = 35 nM PMID: 19239259
ZINC03937475 agonist Compound 31 IC50 = 3.3 nM PMID: 19239259
ZINC03952841 agonist Compound 14a IC50 = 1.4 nM PMID: 11170650
ZINC03972269 antagonist CP-394531 Ki = 0.10 +/- 0.02 nM Kif = 4.1 +/- 0.8 nM PMID: 12036351
ZINC03972270 antagonist CP-409069 Ki = 0.17 +/- 0.02 nM Kif = 10 +/- 0.7 nM PMID: 12036351
ZINC03992105 agonist fluticasone furoate EC50 = 0.49 nM PMID: 21880489
ZINC04026402 antagonist Compound 6 IC50 = 133 nM PMID: 15456242
ZINC04083557 agonist cortisone PMID: 8136304
ZINC04340309 agonist Cortisol Kd = 11.7 +/- 0.8 nM EC50 = 32 nM PMID: 10611474
ZINC04428529 agonist progesterone PMID: 17509631
AR
ZINC05029557 agonist MPA PMID: 16189295 AR
ZINC05663749 agonist deacylcortivazol Activation potency = 0.1 nM PMID: 18160712
ZINC05934541 agonist Compound 13 EC150 = 3.1 µM PMID: 19592245
ZINC06161074 antagonist Compound 4 Ki = 24 nM GR Funct Ki = 100 nM PMID: 17587578
ZINC12349485 antagonist Compound 4 Ki = 5.96 +/- 0.49 nM Inhibition = 35 % at 1µM PMID: 12036351
ZINC12349532 antagonist Compound 4 IC50 = 28 nM IC50 = 250 nM PMID: 15081010
ZINC13473931 antagonist RU-43044 Ki  = 0.10 +/- 0.01 nM Kif = 12 +/- 0.8 nM PMID: 12036351
ZINC13482008 agonist Compound 4 RLA = 1.66 +/- 0.236 PMID: 17067160
ZINC13490440 agonist Compound 11d IC50 = 1929 nM PMID: 12781198
ZINC13490446 agonist Compound 11j IC50 = 689 nM PMID: 12781198 MR
ZINC13490451 agonist Compound 11o IC50 = 753 nM PMID: 12781198
ZINC13490452 agonist Compound 11p IC50 = 2170 nM PMID: 12781198 PR
ZINC13490453 agonist Compound 11q IC50 = 194 nM PMID: 12781198
ZINC13560787 agonist Compound 21 IC50 = 2.5 nM EC50 = 57.2 nM PMID: 15115388
ZINC13560788 agonist Compound 25 IC50 = 0.8 nM EC50 = 35.6 nM PMID: 15115388
ZINC13560793 agonist Compound 31 IC50 = 1.1 nM EC50 = 255.7 nM PMID: 15115388
ZINC13583443 antagonist Compound 7 IC50 = 1294 nM PMID: 15456242
ZINC13583446 antagonist Compound 8 IC50 = 125 nM PMID: 15456242
ZINC13780964 antagonist Compound 2 IC50 = 27 +/- 4 nM PMID: 10743938
ZINC14209763 antagonist Compound 12 IC50 = 4.8 nM IC50 = 440 nM PMID: 16078847
ZINC14209765 antagonist Compound 14 IC50 = 5.4 nM IC50 = 255 nM PMID: 16078847
ZINC14300324 agonist Compound 27 PMID: 11170650
ZINC14300326 agonist Compound 23b IC50 = 6.4 nM PMID: 11170650
ZINC14968704 antagonist Compound 44 IC50 = 84 nM IC50 = 45 nM PMID: 16386422
ZINC14968708 antagonist Compound 45 IC50 = 220 nM IC50 = 260 nM PMID: 16386422
ZINC14970221 antagonist Compound 15 IC50 = 2.6 nM IC50 = 500 nM PMID: 16078847
ZINC18185774 agonist Compound 23 EC150 = 18.0 µM PMID: 19592245
ZINC18825330 agonist genistein EC150 = 4.4 µM
PMID: 19592245
ER_alpha
ZINC18847034 agonist daidzein EC150 = 10.1 µM PMID: 19592245
ER_alpha
ZINC18847037 agonist biochanin A EC150 = 4.2 µM PMID: 19592245 ERR_alpha
ZINC18847044 agonist puruetun EC150 = 3.2 µM PMID: 19592245
ZINC19132424 antagonist E-guggulsterone Ki = 224 +/- 26 nM IC50 = 1740 +/- 150 nM PMID: 16250653
        MR
ZINC26277143 antagonist Compound 61 IC50 = 15 nM IC50 = 100 nM PMID: 15081010
ZINC26279932 antagonist Compound 52 IC50 = 47 nM IC50 = 240 nM PMID: 15081010
ZINC26280471 antagonist Compound 26 IC50 = 138 nM IC50 = 400 nM PMID: 15081010
ZINC26280948 antagonist Compound 60 IC50 = 13 nM IC50 = 340 nM PMID: 15081010
ZINC26285061 antagonist Compound 37 IC50 = 96 nM IC50 = 580 nM PMID: 15081010
ZINC26285914 antagonist Compound 34 IC50 = 12 nM IC50 = 270 nM PMID: 15081010
ZINC26286533 antagonist Compound 14 IC50 = 56 nM IC50 = 840 nM PMID: 15261264
ZINC26289366 antagonist Compound 53 IC50 = 17 nM IC50 = 300 nM PMID: 15081010
ZINC26289683 antagonist Compound 47 IC50 = 110 nM IC50 = 700 nM PMID: 15081010
ZINC26289726 antagonist Compound 35 IC50 = 14 nM IC50 = 150 nM PMID: 15081010
ZINC26290044 antagonist Compound 19 IC50 = 5.7 nM IC50 = 210 nM PMID: 15081010
ZINC26291848 antagonist Compound 55 IC50 = 100 nM IC50 = 160 nM PMID: 15081010
ZINC26291882 antagonist Compound 39 IC50 = 48 nM IC50 = 810 nM PMID: 15081010
ZINC26292318 antagonist Compound 42 IC50 = 42 nM IC50 = 260 nM PMID: 15081010
ZINC26293239 antagonist Compound 54 IC50 = 58 nM IC50 = 1100 nM PMID: 15081010
ZINC26376349 antagonist Compound 45 IC50 = 250 nM IC50 = 450 nM PMID: 15081010
ZINC28349431 antagonist Compound 3 IC50 = 13 nM IC50 = 340 nM PMID: 15261264
ZINC28349438 antagonist Compound 24 IC50 = 9.2 nM IC50 = 2900 nM PMID: 15261265
ZINC28357634 antagonist Compound 18 IC50 = 2.4 nM IC50 = 73 nM PMID: 15261264
ZINC28359384 antagonist Compound 4 IC50 = 2.7 nM IC50 = 240 nM PMID: 15261264
ZINC28362538 antagonist Compound 30 IC50 = 11 nM IC50 = 660 nM PMID: 15261264
ZINC28366102 antagonist Compound 21 IC50 = 37 nM IC50 = 76 nM PMID: 15261265
ZINC28366106 antagonist Compound 22 IC50 = 6.8 nM IC50 = 18 nM PMID: 15261265
ZINC28366209 antagonist Compound 23 IC50 = 2.3 nM IC50 = 23 nM PMID: 15261265
ZINC28367184 antagonist Compound 16 IC50 = 19 nM IC50 = 330 nM PMID: 15261264
ZINC28367190 antagonist Compound 17 IC50 = 5.4 nM IC50 = 280 nM PMID: 15261264
ZINC28369386 antagonist Compound 31 IC50 = 11 nM IC50 = 130 nM PMID: 15261264
ZINC28369393 antagonist Compound 32 IC50 = 3.9 nM IC50 = 640 nM PMID: 15261264
ZINC28369400 antagonist Compound 4 IC50 = 0.6 nM IC50 = 86 nM PMID: 16078847
ZINC28372960 antagonist Compound 20 IC50 = 2.2 nM IC50 = 180 nM PMID: 15261264
ZINC28468499 antagonist Compound 13 IC50 = 1.8 nM IC50 = 330 nM PMID: 16078847
ZINC28703533 antagonist Compound 6a IC50 = 86.5 nM PMID: 17169557 PR
ZINC28703558 antagonist Compound 6b IC50 = 204.3 nM PMID: 17169557 PR
ZINC28703592 antagonist Compound 6c IC50 = 33.4 nM PMID: 17169557 PR
ZINC28703594 antagonist Compound 6d IC50 = 55.5 nM PMID: 17169557 PR
ZINC28703596 antagonist Compound 6e IC50 = 166.9 nM PMID: 17169557 PR
ZINC28703598 antagonist Compound 6f IC50 = 558.0 nM PMID: 17169557
ZINC28703600 antagonist Compound 6g IC50 = 315 nM PMID: 17169557 PR
ZINC28703603 antagonist Compound 6i IC50 = 304 nM PMID: 17169557 PR
ZINC28707960 antagonist Compound 5 Ki = 20 nM GR Funct Ki = 190 nM PMID: 17587578
ZINC28707983 antagonist Compound 11 Ki = 19 nM GR Funct Ki = 150 nM PMID: 17587578
ZINC28707987 antagonist Compound 12 Ki = 8.1 nM GR Funct Ki = 93 nM PMID: 17587578
ZINC28708007 antagonist Compound 17 Ki = 8.7 nM GR Funct Ki = 50 nM PMID: 17587578
ZINC28708009 antagonist Compound 18 Ki = 9.1 nM GR Funct Ki = 96 nM PMID: 17587578
ZINC28708010 antagonist Compound 19 Ki = 31 nM GR Funct Ki = 260 nM PMID: 17587578
ZINC28708011 antagonist Compound 20 Ki = 14 nM GR Funct Ki = 65 nM PMID: 17587578
ZINC28708023 antagonist Compound 25 Ki = 7.1 nM GR Funct Ki = 88 nM PMID: 17587578
ZINC28708035 antagonist Compound 30 Ki = 4.9 nM GR Funct Ki = 97 nM PMID: 17587578
ZINC28708044 antagonist Compound 32 Ki = 9.2 nM GR Funct Ki = 158 nM PMID: 17587578
ZINC28709051 antagonist Compound 11 Ki = 1.8 nM Ki (hGRAF) = 12 nM PMID: 17070047
ZINC28709055 antagonist Compound 13 Ki = 0.6 nM Ki (hGRAF) = 90 nM PMID: 17070047
ZINC28709057 antagonist Compound 14 Ki = 1.8 nM Ki (hGRAF) = 4.4 nM PMID: 17070047
ZINC28709059 antagonist Compound 15 Ki = 4.8 nM Ki (hGRAF) = 15 nM PMID: 17070047
ZINC28709060 antagonist Compound 16 Ki = 2.7 nM Ki (hGRAF) = 91.8 nM PMID: 17070047
ZINC28709062 antagonist Compound 17 Ki = 3.0 nM Ki (hGRAF) = 30 nM PMID: 17070047
ZINC28709064 antagonist Compound 18 Ki = 35 nM Ki (hGRAF) = 765 nM PMID: 17070047
ZINC28709067 antagonist Compound 19 Ki = 0.5 nM Ki (hGRAF) = 21 nM PMID: 17070047
ZINC28709069 antagonist Compound 20 Ki = 1.1 nM Ki (hGRAF) = 39 nM PMID: 17070047
ZINC28709072 antagonist Compound 21 PMID: 17070047
ZINC28709075 antagonist Compound 22 PMID: 17070047
ZINC28709077 antagonist Compound 23 PMID: 17070047
ZINC28817997 antagonist Compound 4c IC50 = 65.1 nM PMID: 17317167 PR
ZINC28818001 antagonist Compound 4d IC50 = 64.8 nM PMID: 17317167 PR
ZINC28818019 antagonist Compound 4e IC50 = 62.7 nM PMID: 17317167 PR
ZINC28818021 antagonist Compound 4f IC50 = 113.2 nM PMID: 17317167 PR
ZINC28818022 antagonist Compound 4g IC50 = 51.0 nM PMID: 17317167 PR
ZINC28818123 antagonist Compound 4h IC50 = 56.6 nM PMID: 17317167 PR
ZINC28818139 antagonist Compound 4i IC50 = 48.9 nM PMID: 17317167 PR
ZINC28818168 antagonist Compound 4j IC50 = 36.3 nM PMID: 17317167 PR
ZINC28818191 antagonist Compound 4k IC50 = 45.4 nM PMID: 17317167 PR
ZINC28818193 antagonist Compound 4l IC50 = 37.6 nM PMID: 17317167 PR
ZINC28818194 antagonist Compound 4m IC50 = 43.5 nM PMID: 17317167 PR
ZINC28818200 antagonist Compound 4n IC50 = 31.3 nM PMID: 17317167 PR
ZINC28818202 antagonist Compound 4o IC50 = 22.1 nM PMID: 17317167 PR
ZINC28818204 antagonist Compound 4p IC50 = 111.0 nM PMID: 17317167 PR
ZINC28818206 antagonist Compound 4q IC50 = 80.3 nM PMID: 17317167 PR
ZINC28818208 antagonist Compound 4r IC50 = 41.3 nM PMID: 17317167 PR
ZINC28818209 antagonist Compound 4s IC50 = 65.8 nM PMID: 17317167 PR
ZINC28818211 antagonist Compound 4t IC50 = 34.4 nM PMID: 17317167 PR
ZINC28818213 antagonist Compound 4u IC50 = 175.3 nM PMID: 17317167 PR
ZINC28818230 antagonist Compound 4v IC50 = 341.6 nM PMID: 17317167 PR
ZINC28818248 antagonist Compound 4w IC50 = 246.5 nM PMID: 17317167 PR
ZINC28818261 antagonist Compound 4x IC50 = 56.0 nM PMID: 17317167 PR
ZINC28950463 antagonist Compound 4b IC50 = 10.0 nM PMID: 17258455 PR
ZINC28950465 antagonist Compound 4d IC50 = 9.0 nM PMID: 17258455 PR
ZINC28950467 antagonist Compound 4e IC50 = 10.0 nM PMID: 17258455 PR
ZINC28950469 antagonist Compound 5a IC50 = 56.3 nM PMID: 17258455 PR
ZINC28953686 antagonist Compound (R)-37 Ki = 4 nM GR functional Ki = 200 nM PMID: 17822897
ZINC28953754 antagonist Compound (R)-47 Ki = 4 nM GR functional Ki = 200 nM PMID: 17822897
ZINC28954897 antagonist Compound 2b IC50 = 210 nM PMID: 17855092 PR
ZINC28954900 antagonist Compound 2c IC50 = 460 nM PMID: 17855092 PR
ZINC28954906 antagonist Compound 2e IC50 = 23 nM PMID: 17855092 PR
ZINC28954908 antagonist Compound 2f IC50 = 82 nM PMID: 17855092 PR
ZINC28954911 antagonist Compound 2g IC50 = 540 nM PMID: 17855092 PR
ZINC28954915 antagonist Compound 2i IC50 = 660 nM PMID: 17855092 PR
ZINC29041831 agonist Compound 18 RLA = 1.60 +/- 0.40 PMID: 18177009
ZINC29041872 agonist Compound 16 RLA = 2.07 +/- 1.13 PMID: 18177009
ZINC29041874 agonist Compound 12 RLA = 1.34 +/- 0.140 PMID: 17067160
ZINC29042282 agonist Compound 13 RLA = 1.69 +/- 0.58 PMID: 18177009
ZINC29135990 antagonist 21OH-6,19-OP PMID: 18284186
ZINC29473104 antagonist Compound 4 relative affinity = 0.0087 IC50 = 77 µM PMID: 2061919
ZINC34270767 agonist Compound (R)-2 IC50 = 10 nM IC50 = 6 nM PMID: 21963986
ZINC34272241 agonist Compound (R)-29 IC50 = 12 nM IC50 = 7 nM PMID: 21963986
ZINC34598637 agonist Compound 2 RLA = 1.69 +/- 0.257 PMID: 17067160
ZINC34633704 antagonist Compound 4a IC50 = 10.0 nM PMID: 17258455 PR
ZINC34633705 antagonist Compound 4c IC50 = 3.0 nM PMID: 17258455 PR
ZINC34633706 antagonist Compound4f IC50 = 20.0 nM PMID: 17258455 PR
ZINC34640800 agonist Compound 21 Ki = 1.8 nM EC50 = 36 +/- 17 nM PMID: 21316964
ZINC347802080 antagonist Compound 6d IC50 = 1.5 nM IC50 = 20.9 nM PMID: 16987661
ZINC34799884 antagonist Compound 10 IC50 = 1812 nM PMID: 15456242
ZINC34799888 antagonist Compound 9 IC50 = 979 nM PMID: 15456242
ZINC34799892 antagonist Compound 11 IC50 = 870 nM PMID: 15456242
ZINC34802066 antagonist Compound 6e IC50 = 0.7 nM IC50 = 4.2 nM PMID: 16987661
ZINC34802068 antagonist Compound 6j IC50 = 6.1 nM IC50 = 43.0 nM PMID: 16987661
ZINC34802069 antagonist Compound 6k IC50 = 0.7 nM IC50 = 10.1 nM PMID: 16987661
ZINC34802070 antagonist Compound 6l IC50 = 9.0 nM IC50 = 32.0 nM PMID: 16987661
ZINC34802071 antagonist Compound 6f IC50 = 1.5 nM IC50 = 18.8 nM PMID: 16987661
ZINC34802072 antagonist Compound 6m IC50 = 0.4 nM IC50 = 2.8 nM PMID: 16987661
ZINC34802073 antagonist Compound 6n IC50 = 3.2 nM IC50 = 15.0 nM PMID: 16987661
ZINC34802074 antagonist Compound 6g IC50 = 4.5 nM IC50 = 28.6 nM PMID: 16987661
ZINC34802075 antagonist Compound 6a IC50 = 0.9 nM IC50 = 7.6 nM PMID: 16987661 PR
ZINC34802077 antagonist Compound 6b IC50 = 0.6 nM IC50 = 1.8 nM PMID: 16987661
ZINC34802078 antagonist Compound 6h IC50 = 0.1 nM IC50 = 1.1 nM PMID: 16987661
ZINC34802079 antagonist Compound 6c IC50 = 0.4 nM IC50 = 4.7 nM PMID: 16987661
ZINC35066338 agonist Compound 3 RLA = 1.34 +/- 0.149 PMID: 17067160
ZINC35066353 agonist Compound 10 RLA = 1.49 +/- 0.209 PMID: 17067160
ZINC35066360 agonist Compound 14 RLA = 1.37 +/- 0.257 PMID: 17067160
ZINC35966237 agonist Compound 3 Ki = 1.7 +/- 0.4 nM EC50 = 7.1 +/- 4.8 nM PMID: 21316964
ZINC35968074 agonist Compound (R)-17 IC50 = 4.7 nM IC50 = 3.0 nM PMID: 20735001
ZINC35983912 agonist Compound (R)-6 IC50 = 1.4 nM IC50 = 6.0 nM PMID: 20735001
ZINC35983913 agonist Compound (S)-6 IC50 = 1700 nM IC50 = 430 nM PMID: 20735001
ZINC40368887 agonist Compound 18 IC50 = 5.6 nM PMID: 19239259
ZINC40379709 agonist Compound 36 IC50 = 360 nM PMID: 19239259
ZINC40847894 agonist Compound 23 IC50 = 3 nM PMID: 19239259
ZINC40847896 agonist Compound 24 IC50 = 2.3 nM PMID: 19239259
ZINC40892595 agonist Compound 2 IC50 = 6.2 nM PMID: 19239259
ZINC40892959 agonist Compound 33 IC50 = 1.5 nM PMID: 19239259
ZINC43010258 antagonist Compound 1c IC50 = 17 nM PMID: 19217285
ZINC43077888 antagonist Compound 1k IC50 = 41 nM PMID: 19217285
ZINC43120258 antagonist Compound 1h IC50 = 58 nM PMID: 19217285
ZINC43120912 antagonist Compound 1a IC50 = 1400 nM PMID: 19217285 PR
ZINC43152620 agonist Compound (R)-16 IC50 = 2.1 nM IC50 = 2.8 nM PMID: 20735001
ZINC43205590 agonist Compound 4 EC50 = 0.78 nM PMID: 21880489
ZINC45259998 agonist Compound 46 Ki = 11 +/- 0.0 nM EC50 = 760 +/- 170 nM PMID: 20047280
ZINC49034416 antagonist Compound 20c pIC50 = 7.8 nM pIC50 = 5.7 PMID: 20469868
ZINC49034922 antagonist Compound 19b pIC50 = 7.6 nM pIC50 = 5.5 PMID: 20469868
ZINC49035502 antagonist Compound 19a pIC50 = 7.9 nM pIC50 = 5.9 PMID: 20469868
ZINC49035686 antagonist Compound 20a pIC50 = 8.0 nM pIC50 = 5.7 PMID: 20469868
ZINC49037241 antagonist Compound 19e pIC50 = 7.5 nM pIC50 = 5.5 PMID: 20469868
ZINC49037527 antagonist Compound 19f pIC50 = 7.4 nM pIC50 = 5.5 PMID: 20469868
ZINC49048200 antagonist Compound 19c pIC50 = 7.7 nM pIC50 = 5.7 PMID: 20469868
ZINC49053928 antagonist Compound 19d pIC50 = 7.8 nM pIC50 = 5.7 PMID: 20469868
ZINC49073159 antagonist GSK1564023A pIC50 = 7.0 PMID: 20202837 PR
ZINC49089100 antagonist Compound 20d pIC50 = 7.8 nM pIC50 = 5.8 PMID: 20469868
ZINC49109380 antagonist GSK325971A pIC50 = 6.7 PMID: 20202837 PR
ZINC49775625 agonist Compound 23d pIC50 = 7.8 pEC50 = 6.6 PMID: 20469868
ZINC49777278 agonist Compound 23c pIC50 = 7.4 pEC50 = 6.6 PMID: 20469868
ZINC49778018 agonist Compound 23a pIC50 = 8.0 pEC50 = 7.7 PMID: 20469868
ZINC49792400 agonist Compound 23e pIC50 = 7.3 pEC50 = 6.7 PMID: 20469868
ZINC53194977 antagonist Compound 11 IC50 = 900 +/- 170 nM PMID: 10743938
ZINC53195016 antagonist Compound 12 IC50 = 35 +/- 8 nM PMID: 10743938 MR
ZINC59241872 agonist Compound 32 IC50 = 2.5 nM PMID: 19239259
ZINC62178913 antagonist Compound 1j IC50 = 110 nM PMID: 19217285
ZINC62178922 antagonist Compound 1e IC50 = 20 nM PMID: 19217285 PR
ZINC62178927 antagonist Compound 1b IC50 = 68 nM PMID: 19217285 PR
ZINC62178929 antagonist Compound 2b IC50 = 132 nM PMID: 19217285 PR
ZINC62178931 antagonist Compound 2a IC50 = 62 nM PMID: 19217285 PR
ZINC62178934 antagonist Compound 1l IC50 = 21 nM PMID: 19217285 PR
ZINC64286987 agonist Compound (R)-7 IC50 = 1.4 nM IC50 = 2.0 nM PMID: 20735001
ZINC66065864 agonist Compound 12d pIC50 = 7.8 +/- 0.15 agonism pIC50 = 7.3 +/- 0.17 PMID: 21257309
ZINC66066171 agonist Compound 20 Ki = 10.4 nM EC50 = 112 +/- 40 nM PMID: 21316964
ZINC66066317 agonist Compound 20a pIC50 = 8.1 +/- 0.31 agonism pIC50 = 6.7 +/- 0.09 PMID: 21257309
ZINC66066318 agonist Compound 20c pIC50 = 7.5 +/- 0.19 agonism pIC50 = 6.9 +/- 0.24 PMID: 21257309
ZINC66066319 agonist Compound 20b pIC50 = 7.4 +/- 0.09 agonism pIC50 = 6.7 +/- 0.18 PMID: 21257309
ZINC66066666 agonist Compound 20d pIC50 = 7.5 +/- 0.12 agonism pIC50 = 7.3 +/- 0.24 PMID: 21257309
ZINC66066667 agonist Compound 20e pIC50 = 6.8 agonism pIC50 = 5.4 +/- 0.08 PMID: 21257309
ZINC66074239 agonist Compound 10 Ki = 1.2 +/- 0.2 nM EC50 = 0.9 +/- 0.6 nM PMID: 21316964
ZINC66074240 agonist Compound 11 Ki = 11.7 nM EC50 = 16 +/- 1.0 nM PMID: 21316964
ZINC66074241 agonist Compound 12 Ki = 319 nM EC50 = 105 +/- 45 nM PMID: 21316964
ZINC66074484 agonist Compound 10 Ki = 7.8 nM EC50 = 89 +/- 20 nM PMID: 21349714
ZINC66074485 agonist Compound 11 Ki = 4.3 +/- 2.7 nM EC50 = 70 +/- 53 nM PMID: 21349714
ZINC66074723 agonist Compound 14c pIC50 = 8.1 +/- 0.43 agonism pIC50 = 8.1 +/- 0.16 PMID: 21257309
ZINC66074725 agonist Compound 14d pIC50 = 7.8 +/- 0.23 agonism pIC50 = 7.2 +/- 0.05 PMID: 21257309
ZINC66075425 agonist Compound 14e pIC50 = 7.6 +/- 0.07 agonism pIC50 = 6.8 +/- 0.25 PMID: 21257309
ZINC66075682 agonist Compound 14i pIC50 = 7.9 +/- 0.01 agonism pIC50 = 8.6 +/- 0.13 PMID: 21257309
ZINC66075685 agonist Compound 14j pIC50 = 7.8 +/- 0.31 agonism pIC50 = 8.7 +/- 0.1 PMID: 21257309
ZINC66075688 agonist Compound 14k pIC50 = 8.3 agonism pIC50 = 8.8 +/- 0.06 PMID: 21257309
ZINC66076087 agonist Compound 8 Ki = 9.0 nM EC50 = 108 +/- 34 nM PMID: 21316964
ZINC66076089 agonist Compound 9 Ki = 2.3 +/- 0.3 nM EC50 = 56 +/- 33 nM PMID: 21316964
ZINC66076519 agonist Compound 13 Ki = 6.2 nM EC50 = 105 +/- 8 nM PMID: 21349714
ZINC66076521 agonist Compound 14 Ki = 7.6 +/- 0.2 nM EC80 = 7.6 +/- 2.7 nM PMID: 21349714
ZINC66076532 agonist Compound 17 Ki = 6.7 +/- 1.1 nM EC50 = 5.8 +/- 1.8 nM PMID: 21349714
ZINC66076534 agonist Compound 18 Ki = 12.2 nM EC50 = 18 +/- 6 nM PMID: 21349714
ZINC66076537 agonist Compound 13 Ki = 6.9 nM EC50 = 0.4 +/- 0.2 nM PMID: 21316964
ZINC66077309 agonist Compound 12a pIC50 = 7.8 +/- 0.09 agonism pIC50 = 8.4 +/- 0.04 PMID: 21257309
ZINC66077312 agonist Compound 12c pIC50 = 7.8 +/- 0.16 agonism pIC50 = 7.6 +/- 0.16 PMID: 21257309
ZINC66077575 agonist Compound 21 Ki = 70 nM EC50 = 178 +/- 40 nM PMID: 21349714
ZINC66077576 agonist Compound 22 Ki = 30 nM EC50 = 15 +/- 6 nM PMID: 21349714
ZINC66077743 agonist Compound 14 Ki = 1.5 nM EC50 = 0.2 +/- 0.1 nM PMID: 21316964
ZINC66077744 agonist Compound 16 Ki = 3.5 nM EC50 = 3.7 +/- 1.7 nM PMID: 21316964
ZINC66077747 agonist Compound 18 Ki = 16.6 nM EC50 = 5.7 +/- 0.9 nM PMID: 21316964
ZINC66077958 agonist Compound 16 Ki = 11.6 nM EC50 = 11 +/- 3 nM PMID: 21349714
ZINC66078257 agonist Compound 23 Ki = 5.1 nM EC50 = 3.5 +/- 22 nM PMID: 21349714
ZINC66078260 agonist Compound 24 Ki = 2.9 nM EC50 = 16 +/- 10 nM PMID: 21349714
ZINC66078262 agonist Compound 25 Ki = 13.7 nM EC50 = 24 +/- 5 nM PMID: 21349714
ZINC66078326 agonist Compound 17 Ki = 19.6 nM EC50 = 40 +/- 12 nM PMID: 21316964
ZINC66078498 agonist Compound 19 Ki = 1.3 nM EC50 = 9.6 +/- 3.1 nM PMID: 21316964
ZINC66078858 agonist Compound 9 Ki = 6.8 nM EC50 = 17 +/- 4 nM PMID: 21349714
ZINC66079518 agonist Compound 14h pIC50 = 8.1 +/- 0.11 agonism pIC50 = 8.9 +/- 0.22 PMID: 21257309
ZINC66079573 agonist Compound 7 Ki = 3.0 nM EC50 = 39 +/- 20 nM PMID: 21349714
ZINC66080332 agonist Compound 15 Ki = 6.0 nM EC50 = 34 nM PMID: 21316964
ZINC66097227 agonist Compound 22 Ki = 0.9 +/- 0.8 nM EC50 = 40 +/- 29 nM PMID: 21316964
ZINC66097473 agonist Compound 28 Ki = 5.0 nM EC50 = 16 +/- 10 nM PMID: 21316964
ZINC66097476 agonist Compound 29 Ki = 1.0 nM EC50 = 1.3 +/- 0.1 nM PMID: 21316964
ZINC66097478 agonist Compound 30 Ki = 157 nM EC50 = 480 +/- 0.4 nM PMID: 21316964
ZINC66097481 agonist Compound 31 Ki = 2.5 +/- 1.0 nM EC50 = 0.6 +/- 0.2 nM PMID: 21316964
ZINC66097593 agonist Compound 19 Ki = 16.1 nM EC50 = 21 +/- 5 nM PMID: 21349714
ZINC66097596 agonist Compound 20 Ki = 13.7 nM EC50 = 5.1 +/- 2.0 nM PMID: 21349714
ZINC66097730 agonist Compound 12e pIC50 = 7.8 +/- 0.24 agonism pIC50 = 8.3 +/- 0.07 PMID: 21257309
ZINC66097734 agonist Compound 12f pIC50 = 7.5 agonism pIC50 = 7.9 +/- 0.02 PMID: 21257309
ZINC66098023 agonist Compound 23 Ki = 38.3 nM EC50 = 205 +/- 92 nM PMID: 21316964
ZINC66098028 agonist Compound 25 Ki = 3.1 nM EC50 = 18 +/- 0.6 nM PMID: 21316964
ZINC66098030 agonist Compound 26 Ki = 8.0 nM EC50 = 89 +/- 17 nM PMID: 21316964
ZINC66098334 agonist Compound 27 Ki = 2.4 nM EC50 = 11 +/- 4.6 nM PMID: 21316964
ZINC66098629 agonist Compound 14a pIC50 = 7.7 +/- 0.3 agonism pIC50 = 6.6 +/- 0.52 PMID: 21257309
ZINC66098631 agonist Compound 14b pIC50 = 7.9 +/- 0.24 agonism pIC50 = 8.0 +/- 0.27 PMID: 21257309
ZINC66098739 agonist Compound 26 Ki = 9.4 nM EC50 = 29 +/- 9 nM PMID: 21349714
ZINC66098934 agonist Compound 8 Ki = 2.2 nM EC50 = 21 +/- 4 nM PMID: 21349714
ZINC66101397 agonist Compound 19b pIC50 = 7.9 +/- 0.04 agonism pIC50 = 7.1 +/- 0.27 PMID: 21257309
ZINC66101400 agonist Compound 19c pIC50 = 7.4 agonism pIC50 = 7.3 +/- 0.03 PMID: 21257309
ZINC66101461 agonist Compound 19d pIC50 = 7.8 +/- 0.09 agonism pIC50 = 7.9 +/- 0.21 PMID: 21257309
ZINC66156695 agonist Compound 14g pIC50 = 8.2 +/- 0.08 agonism pIC50 = 9.3 +/- 0.03 PMID: 21257309
ZINC66252243 antagonist Compound 21 pEC50 = 7.9 PEC50 = 7 PMID: 21129964
ZINC66259871 antagonist Compound 2 pEC50 = 8.4 pEC50 = 7.3 PMID: 21129964
ZINC68149724 agonist Compound 8 EC50 = 3.93 nM PMID: 21880489
ZINC68149728 agonist Compound 13 EC50 = 1.87 nM PMID: 21880489
ZINC68149732 agonist Compound 15 EC50 = 2.97 nM PMID: 21880489
ZINC70631578 antagonist Compound 1g IC50 = 7 nM PMID: 19217285 PR
ZINC70631579 antagonist Compound 1d IC50 = 102 nM PMID: 19217285 PR
ZINC70631580 antagonist Compound 1m IC50 = 26 nM PMID: 19217285 PR
ZINC71317430 agonist Compound 17 Ki = 2.7 nM  EC50 = 0.6 +/- 0.2 nM PMID: 21324689
ZINC71318143 agonist Compound 15 Ki = 2.2 nM  EC50 = 5.0 +/- 0.7 nM PMID: 21324689
ZINC71318994 agonist Compound 22 Ki = 0.8 nM  EC50 = 19 +/- 7.4 nM PMID: 21324689
ZINC71388864 agonist Compound 16 Ki = 2.0 nM  EC50 = 3.4 +/- 0.4 nM PMID: 21324689
ZINC72102693 antagonist Compound 1f IC50 = 150 nM PMID: 19217285 PR
ZINC72108062 agonist Compound (S)-13 Ki = 1.2 nM PMID: 21073190
ZINC72108874 agonist Compound (S)-22 Ki = 1.2 nM PMID: 21073190
ZINC72109246 agonist Compound (S)-20 Ki = 0.9 nM PMID: 21073190
ZINC72109958 agonist Compound (S)-17 Ki = 0.7 nM PMID: 21073190
ZINC72110039 agonist Compound (S)-19 Ki = 0.4 nM PMID: 21073190
ZINC72110089 agonist Compound 29 Ki = 0.3 nM PMID: 21073190
ZINC72110231 agonist Compound (S)-23 Ki = 0.7 nM PMID: 21073190
ZINC72110232 agonist Compound (S)-24 Ki = 0.4 nM PMID: 21073190
ZINC72110233 agonist Compound 25 Ki = 2.2 nM PMID: 21073190
ZINC72111146 agonist Compound 30 Ki = 0.8 nM PMID: 21073190
ZINC72124728 agonist Compound 5 EC50 = 0.43 nM PMID: 21880489
ZINC72125900 agonist Compound 14 EC50 = 2.82 nM PMID: 21880489
ZINC72126297 agonist Compound 9 EC50 = 0.38 nM PMID: 21880489
ZINC72126305 agonist Compound 11 EC50 = 7.35 nM PMID: 21880489
ZINC72126306 agonist Compound 12 EC50 = 1.75 nM PMID: 21880489
ZINC72126852 agonist Compound 10 EC50 = 21.10 nM PMID: 21880489
ZINC72126990 agonist Compound 6 EC50 = 8.78 nM PMID: 21880489
ZINC72126991 agonist Compound 7 EC50 = 0.71 nM PMID: 21880489
ZINC73129958 agonist Compound (R)-21 IC50 = 1 nM IC50 = 3 nM PMID: 21963986
ZINC73140635 agonist Compound (R)-33 IC50 = 2 nM IC50 = 28 nM PMID: 21963986
ZINC73200525 antagonist Compound 5a IC50 = 45 nM PMID: 22260770 PR
ZINC73200527 antagonist Compound 5b IC50 = 23 nM PMID: 22260770 PR
ZINC73200529 antagonist Compound 5c IC50 = 13 nM PMID: 22260770 PR