Compound ID	Pharmacological profile	Compound name	Binding data	Activity data	Bibliographic ref.	Cross-reactivity
CHEMBL511173	agonist	Compound 16		CAR activation = 1.45 +/- 0.16	PMID: 18983136
ZINC00378510	agonist	Compound 18		CAR activation = 5.22 +/- 0.01	PMID: 18983136
ZINC00395304	agonist	Compound 4		CAR activation = 4.17 +/- 0.14	PMID: 18983136
ZINC01583667	agonist	TMPP		CAR activation = 2.45 +/- 0.19	PMID: 18983136
ZINC01688738	agonist	TPP		CAR activation = 3.96 +/- 0.15	PMID: 18983136
ZINC01751810	agonist	TCPOBOP		EC50 = 20 nM	PMID: 10757780	PXR
ZINC02968826	agonist	Compound 15		CAR activation = 1.63 +/- 0.18	PMID: 18983136
ZINC03807804	antagonist	clotrimazole		IC50 = 58 nM	PMID: 12611900	PXR
ZINC03833953	agonist	5β-pregnane-3,20-dione		EC50 = 0.67 µM	PMID: 10748001
ZINC03860432	agonist	di(2-ethylhexyl)phtalate		EC50 = 211 nM	PMID: 19211671
ZINC04660766	agonist	Compound 2		CAR activation = 5.50 +/- 0.35	PMID: 18983136
ZINC05681090	agonist	Compound 13		CAR activation = 2.03 +/- 0.15	PMID: 18983136
ZINC05985275	agonist	Compound 14		CAR activation = 1.86 +/- 0.23	PMID: 18983136
ZINC06352482	agonist	Compound 27		CAR activation = 1.32 +/- 0.01	PMID: 18983136
ZINC06928659	agonist	Compound 22		CAR activation = 2.97 +/- 0.13	PMID: 18983136
ZINC07310221	agonist	Compound 7		CAR activation = 3.28 +/- 0.16	PMID: 18983136
ZINC08105497	agonist	Compound 17		CAR activation = 7.92 +/- 0.05	PMID: 18983136
ZINC08781897	agonist	CITCO		EC50 = 25 nM	PMID: 12611900
ZINC20627259	agonist	Compound 21		CAR activation = 3.68 +/- 0.46	PMID: 18983136
ZINC28330720	antagonist	PK11195			PMID: 18492798
ZINC33670430	agonist	Compound 10		CAR activation = 2.51 +/- 0.19	PMID: 18983136
ZINC33751070	agonist	Compound 8		CAR activation = 2.95 +/- 0.15	PMID: 18983136
ZINC33916362	agonist	Compound 6		CAR activation = 3.80 +/- 0.37	PMID: 18983136
ZINC33918397	agonist	Compound 26		CAR activation = 1.37 +/- 0.10	PMID: 18983136
ZINC35363255	agonist	Compound 12		CAR activation = 2.23 +/- 0.25	PMID: 18983136
ZINC40391083	agonist	Compound 19		CAR activation = 4.47 +/- 0.15	PMID: 18983136
ZINC40391137	agonist	Compound 25		CAR activation = 1.40 +/- 0.01	PMID: 18983136
ZINC40391886	agonist	Compound 5		CAR activation = 3.87 +/- 0.07	PMID: 18983136
ZINC40848033	agonist	Compound 1		CAR activation = 6.35 +/- 0.69	PMID: 18983136
ZINC40859785	agonist	Compound 11		CAR activation = 2.39 +/- 0.11	PMID: 18983136
ZINC40862267	agonist	Compound 23		CAR activation = 2.60 +/- 0.13	PMID: 18983136
ZINC40862269	agonist	Compound 24		CAR activation = 1.76 +/- 0.17	PMID: 18983136
ZINC40874006	agonist	Compound 20		CAR activation = 4.09 +/- 0.36	PMID: 18983136
ZINC40980046	agonist	Compound 3		CAR activation = 4.88 +/- 0.25	PMID: 18983136
ZINC53275892	agonist	Compound 9		CAR activation = 2.70 +/- 0.32	PMID: 18983136