Compound ID | Pharmacological Profile | Compound name | Binding data | Activity data | Bibliographic ref | Cross-Reactivity | ||||||||||||
CHEMBL10778 | antagonist | Compound 10 | CAT activity = 5% | Bioorg. Med. Chem. Lett.1997,7,11,1483 | ||||||||||||||
ZINC03814360 | agonist | DHT | Kd = 0.2 – 0.5 nM | T.A. = 0.001 nM | PMID: 10077001 | |||||||||||||
ZINC03814420 | agonist | R1881 | Kd = 0.6 nM | T.A. = 0.001 nM | PMID: 10077001 | PR | ||||||||||||
ZINC00007581 | agonist | Compound 24 | Ki = 16 +/- 2 nM | EC50 = 3 +/- 0 nM (Eff=114+/-18%) | PMID: 10230629 | |||||||||||||
ZINC00023574 | agonist | Compound 22 | Ki = 11 +/- 3 nM | EC50 = 9 +/- 1 nM (Eff=89+/-9%) | PMID: 10230629 | |||||||||||||
ZINC13581066 | agonist | Compound 14 | Ki = 9 +/- 1 nM | EC50 = 32 +/- 8 nM (Eff=47+/-9%) | PMID: 10230629 | |||||||||||||
ZINC03814396 | antagonist | Compound 16 | Ki = 22 +/- 6 nM | IC50 = 33 +/- 15 nM (Eff=66+/-4%) | PMID: 10230629 | |||||||||||||
ZINC03814404 | agonist | Compound 13 | Ki = 23 nM | EC50 = 66 +/- 35 nM (Eff=30+/-8%) | PMID: 10230629 | |||||||||||||
ZINC95619129 | antagonist | 2-hydroxyflutamide | Ki = 27 +/- 8 nM | IC50 = 15 +/- 2 nM | PMID: 10230629 | PR | ||||||||||||
ZINC13581061 | antagonist | Compound 9 | Ki = 8 +/- 2 nM | IC50 = 11 +/- 2 nM (55+/-5%) | PMID: 10230629 | |||||||||||||
ZINC13581079 | agonist | Compound 23 | Ki = 15 +/- 4 nM | EC50 = 10 +/- 2 nM (Eff=39+/-7%) | PMID: 10230629 | |||||||||||||
ZINC13581081 | agonist | Compound 25 | Ki = 29 +/- 4 nM | EC50 = 20 +/- 5 nM (Eff=64+/-7%) | PMID: 10230629 | |||||||||||||
ZINC13581085 | agonist | Compound 27 | Ki = 32 +/- 10 nM | EC50 = 16 +/- 5 nM (Eff=69+/-9%) | PMID: 10230629 | |||||||||||||
CHEMBL27297 | antagonist | Compound 4b | Ki = 9 +/- 1 nM | IC50 = 20 +/- 1 nM (Eff=45 +/- 11%) | PMID: 10340624 | |||||||||||||
ZINC28763003 | antagonist | Compound 6h | Ki = 58 nM | IC50 =73 +/- 6 nM (Eff=73+/-2%) | PMID: 10340624 | |||||||||||||
ZINC28763203 | agonist | Compound 16 | Ki = 8 nM | EC50 = 9 +/- 3 nM (Eff=56+/-3%) | PMID: 10340624 | |||||||||||||
ZINC28763532 | agonist | Compound 6j | Ki = 8 +/- 2 nM | EC50 = 22 +/- 3 nM (Eff=62+/-11%) | PMID: 10340624 | |||||||||||||
ZINC28763626 | agonist | Compound 6l | Ki = 27 nM | EC50 = 7 +/-3 nM | PMID: 10340624 | |||||||||||||
ZINC28763706 | agonist | Compound 17 | Ki = 2 nM | EC50 = 3 +/- 1 nM (Eff=107+/-6%) | PMID: 10340624 | |||||||||||||
ZINC28763747 | agonist | Compound 6c | Ki = 29 +/- 9 nM | EC50 = 19 +/- 4 nM(Eff=63+/-7%) | PMID: 10340624 | |||||||||||||
ZINC28764963 | agonist | Compound 21 | Ki = 15 nM | EC50 = 2 +/- 0 nM (Eff=86+/-7%) | PMID: 10340624 | |||||||||||||
ZINC03814415 | agonist | norethindrone | PMID: 10350363 | |||||||||||||||
ZINC27331582 | antagonist | Compound 8b | Ki = 5 nM | IC50 = 212 nM (Eff=95%) | PMID: 10743937 | |||||||||||||
ZINC27332000 | antagonist | Compound 7b | Ki = 159 nM | IC50 =72 nM (Eff=83%) | PMID: 10743937 | |||||||||||||
ZINC27408682 | antagonist | Compound 5c | Ki = 84 +/- 22 nM | IC50 = 30 +/- 12 nM (Eff=75+/-3%) | PMID: 10743937 | |||||||||||||
ZINC27414065 | antagonist | Compound 6c | Ki = 11 nM | IC50 = 22 +/- 10 nM (Eff=66/-1%) | PMID: 10743937 | |||||||||||||
ZINC27414229 | antagonist | Compound 22f | Ki = 86 +/- 30 nM | IC50 = 45 +/- 8 nM (Eff=94+/-3%) | PMID: 10743937 | |||||||||||||
ZINC27415171 | antagonist | Compound 12a | Ki = 20 nM | IC50 = 63 +/- 23 nM (Eff=98+/-2%) | PMID: 10743937 | |||||||||||||
ZINC27415551 | antagonist | Compound 9 | Ki = 22 nM | IC50 = 9 +/- 2 nM (Eff=83+/-3%) | PMID: 10743937 | |||||||||||||
ZINC02007483 | agonist | DTIB | Ki = 0.71 +/- 0.22 nM | PMID: 10966753 | ||||||||||||||
ZINC03814409 | agonist | testosterone | Ki = 1.4 +/- 0.4 nM | pEC50 = 8.7 +/- 0.2 | PMID: 10966753 PMID: 19856921 | |||||||||||||
ZINC03814364 | agonist | estradiol | PMID: 11861974 | |||||||||||||||
ZINC04097304 | agonist | 9-alpha-fluorocortisol | PMID: 11906285 | |||||||||||||||
ZINC538564 | antagonist | bicalutamide | PMID: 12015321 | |||||||||||||||
ZINC03814362 | agonist | Compound 33 | Ki = 0.3 +/- 0.1 nM | PMID: 12488554 | ||||||||||||||
ZINC13554387 | agonist | Compound (R)-19 | Ki = 2.9 +/- 0.2 nM | PMID: 12488554 | ||||||||||||||
ZINC03814372 | agonist | Compound (S)-19 | Ki = 123 +/- 27 nM | PMID: 12488554 | ||||||||||||||
ZINC03814375 | agonist | Compound 30 | Ki = 5.0 +/- 0.6 nM | PMID: 12488554 | ||||||||||||||
CHEMBL134277 | antagonist | Compound 18b | Ki = 669 +/- 206 nM | IC50 = 215 +/- 45 nM (Eff=52+/-2%) | PMID: 12954062 | MR | ||||||||||||
CHEMBL336353 | antagonist | Compound 15 | Ki = 819 +/- 423 | IC50 = 1500 nM (Eff=60%) | PMID: 12954062 | |||||||||||||
CHEMBL413309 | antagonist | Compound 9a | Ki = 1456 +/- 289 nM | IC50 = 900 nM (Eff=60%) | PMID: 12954062 | |||||||||||||
ZINC03814359 | agonist | PMID: 14565775 | ||||||||||||||||
ZINC03814361 | agonist | PMID: 14565775 | ||||||||||||||||
ZINC03814418 | agonist | 5-β-dihydrotestosterone | RBA = 137.9008 | PMID: 14565775 | ||||||||||||||
ZINC03814426 | agonist | testosterone propionate | RBA = 0.1615 | PMID: 14565775 | ||||||||||||||
ZINC03814428 | agonist | DHT benzoate | RBA = 1.1801 | PMID: 14565775 | ||||||||||||||
CHEMBL187605 | antagonist | Compound 13 | Ki = 0.040 µM | IC50 = 0.774 µM | PMID: 15546739 | |||||||||||||
CHEMBL188129 | antagonist | Compound 15 | Ki = 0.062 µM | IC50 = 3.32 µM | PMID: 15546739 | |||||||||||||
CHEMBL188261 | antagonist | Compound 19 | Ki = 1.40 µM | IC50 = 0.78 µM | PMID: 15546739 | |||||||||||||
CHEMBL188545 | antagonist | Compound 16 | Ki = 1.03 µM | IC50 = 1.33 µM | PMID: 15546739 | |||||||||||||
ZINC38468066 | antagonist | Compound 17 | Ki = 0.248 µM | IC50 = 2.54 µM | PMID: 15546739 | |||||||||||||
CHEMBL189600 | antagonist | Compound 29 | Ki = 0.124 µM | IC50 = 0.300 µM | PMID: 15546739 | |||||||||||||
CHEMBL362566 | antagonist | Compound 26 | Ki = 0.018 µM | IC50 = 0.200 µM | PMID: 15546739 | |||||||||||||
ZINC28463952 | antagonist | Compound 22 | Ki = 0.237 µM | IC50 = 0.252 µM | PMID: 15546739 | |||||||||||||
ZINC34313811 | antagonist | Compound 32 | Ki = 0.073 µM | IC50 = 0.060 µM | PMID: 15546739 | |||||||||||||
CHEMBL365921 | antagonist | Compound 28 | Ki = 0.041 µM | IC50 = 0.588 µM | PMID: 15546739 | |||||||||||||
CHEMBL447184 | antagonist | Compound 31 | Ki = 0.693 µM | IC50 = 17.9 µM | PMID: 15546739 | |||||||||||||
CHEMBL178886 | antagonist | Compound 3 | Ki = 158 nM | IC50 = 307 nM | PMID: 15603938 | |||||||||||||
CHEMBL184981 | antagonist | Compound 13 | Ki = 83 nM | IC50 = 150 nM | PMID: 15603938 | |||||||||||||
CHEMBL182412 | antagonist | Compound 6 | Ki = 100 nM | IC50 = 196 nM | PMID: 15603938 | |||||||||||||
CHEMBL183882 | antagonist | Compound 8 | Ki = 2810 nM | IC50 = 658 nM | PMID: 15603938 | |||||||||||||
CHEMBL180681 | antagonist | Compound 11 | Ki = 171 nM | IC50 = 68 nM | PMID: 15603938 | |||||||||||||
CHEMBL188297 | antagonist | Compound 4 | Ki = 5 nM | IC50 = 12 nM | PMID: 15603938 | |||||||||||||
CHEMBL361445 | agonist | Compound 5 | Ki = 19 nM | IC50 = 224 nM | PMID: 15603938 | |||||||||||||
CHEMBL369542 | agonist | Compound 7 | Ki = 9 nM | IC50 = 49 nM | PMID: 15603938 | |||||||||||||
CHEMBL178333 | antagonist | Compound 16 | Ki = 117 nM | IC50 = 114 nM | PMID: 15603960 | |||||||||||||
CHEMBL178469 | antagonist | Compound 11 | Ki = 632 nM | IC50 = 744 nM | PMID: 15603960 | |||||||||||||
CHEMBL178957 | antagonist | Compound 22 | Ki = 401 nM | IC50 = 1746 nM | PMID: 15603960 | |||||||||||||
CHEMBL180859 | antagonist | Compound 19 | Ki = 177 nM | IC50 = 517 nM | PMID: 15603960 | |||||||||||||
CHEMBL181571 | antagonist | Compound 21 | Ki = 1 nM | IC50 > 5 nM | PMID: 15603960 | |||||||||||||
CHEMBL181674 | antagonist | Compound 25 | Ki = 11 nM | IC50 = 84 nM | PMID: 15603960 | |||||||||||||
CHEMBL181722 | antagonist | Compound 24 | Ki = 530 nM | IC50 = 1038 nM | PMID: 15603960 | |||||||||||||
CHEMBL182186 | antagonist | Compound 4 | Ki = 192 nM | IC50 = 664 nM | PMID: 15603960 | |||||||||||||
CHEMBL182236 | antagonist | Compound 18 | Ki = 125 nM | IC50 = 220 nM | PMID: 15603960 | |||||||||||||
CHEMBL359911 | antagonist | Compound 3 | Ki = 284 nM | IC50 = 1200 nM | PMID: 15603960 | |||||||||||||
CHEMBL361222 | agonist | Compound 17 | Ki = 46 nM | IC50 = 146 nM | PMID: 15603960 | |||||||||||||
CHEMBL366924 | antagonist | Compound 20 | Ki = 400 nM | IC50 = 2014 nM | PMID: 15603960 | |||||||||||||
CHEMBL367364 | antagonist | Compound 13 | Ki = 1615 nM | IC50 = 317 nM | PMID: 15603960 | |||||||||||||
CHEMBL368906 | antagonist | Compound 14 | Ki = 55 nM | IC50 = 119 nM | PMID: 15603960 | |||||||||||||
CHEMBL197548 | antagonist | Compound 6 | Ki = 2900 nM | IC50 = 820 nM | PMID: 16019211 | |||||||||||||
CHEMBL198037 | antagonist | Compound 5 | Ki = 3380 nM | IC50 = 6800 nM | PMID: 16019211 | |||||||||||||
CHEMBL199238 | antagonist | Compound 9 | Ki = 1170 nM | IC50 = 7.6 nM | PMID: 16019211 | VDR | ||||||||||||
CHEMBL370567 | antagonist | Compound 8 | Ki = 1508 nM | IC50 = 9 nM | PMID: 16019211 | VDR | ||||||||||||
ZINC03814421 | agonist | 11-keto-testosterone | Kd = 4.44 +/- 1.61 nM | PMID: 16107211 | ||||||||||||||
ZINC03991694 | agonist | Compound S-1 | Ki = 6.1 nM | PMID: 16129672 | ||||||||||||||
ZINC04655055 | antagonist | hydroxyflutamide | Ki = 25 nM | PMID: 16129672 | PR | |||||||||||||
ZINC13581050 | agonist | Compound R-3 | Ki = 0.3 nM | PMID: 16129672 | ||||||||||||||
CHEMBL372106 | agonist | Z-gugulsterone | Ki = 315 +/- 13 nM | EC50 = 660 +/- 240 nM | PMID: 16250653 | |||||||||||||
CHEMBL402063 | agonist | E-gugulsterone | Ki = 240 +/- 21 nM | PMID: 16250653 | ||||||||||||||
CHEMBL197595 | antagonist | Compound 33a | IC50 = 0.11 µM (Inh=64 +/- 4.3%) | PMID: 16420057 | ||||||||||||||
CHEMBL200973 | antagonist | Compound 32 | Ki = 4.6 nM | IC50 = 0.20 µM (Inh=53 +/- 3.2 %) | PMID: 16420057 | |||||||||||||
CHEMBL201069 | antagonist | Compound 27 | IC50 = 0.22 µM (Inh = 36 +/- 5.2 %) | PMID: 16420057 | ||||||||||||||
CHEMBL201242 | antagonist | Compound 22 | IC50 = 0.13 µM (Inh = 58 +/- 3.5 %) | PMID: 16420057 | ||||||||||||||
CHEMBL201327 | antagonist | Compound 30 | IC50 = 0.47 µM | PMID: 16420057 | ||||||||||||||
CHEMBL202710 | antagonist | Compound 29 | IC50 = 0.73 µM (Inh = 52 +/- 3.1 %) | PMID: 16420057 | ||||||||||||||
CHEMBL202990 | antagonist | YM-175735 | IC50 = 0.20 µM | PMID: 16420057 | ||||||||||||||
CHEMBL203423 | antagonist | Compound 18 | IC50 = 1.0 µM | PMID: 16420057 | ||||||||||||||
CHEMBL379465 | antagonist | Compound 37 | IC50 = 0.37 µM (Inh =39 +/- 6.9 %) | PMID: 16420057 | ||||||||||||||
CHEMBL381253 | antagonist | Compound 26 | IC50 = 0.17 µM (Inh = 52 +/- 4.2 %) | PMID: 16420057 | ||||||||||||||
CHEMBL439685 | antagonist | Compound 14 | IC50 = 0.12 µM (Inh = 42 +/- 2.2 %) | PMID: 16420057 | ||||||||||||||
ZINC34886714 | antagonist | Compound 1b | RBA = 6.4 | RLA = 0.61 | PMID: 16784849 | |||||||||||||
ZINC34886716 | antagonist | Compound 1h | RBA= 12.6 | RLA = 0.62 | PMID: 16784849 | |||||||||||||
CHEMBL210880 | antagonist | Compound 44 | IC50 (LNCaP) = 0.2 µM | PMID: 16789753 | ||||||||||||||
CHEMBL212610 | antagonist | Compound 40 | IC50 (LNCaP)= 2.6 µM | PMID: 16789753 | ||||||||||||||
CHEMBL212693 | antagonist | Compound 4 | IC50 (LNCaP)= 0.2 µM | PMID: 16789753 | ||||||||||||||
ZINC03874498 | antagonist | nilutamide | IC50 = 4.05 µM | PMID: 16857237 | ||||||||||||||
CHEMBL217168 | antagonist | Compound 4c | Ki = 153 nM | IC50 = 34 +/- 11 nM (Eff=72 +/- 4 %) | PMID: 17034117 | |||||||||||||
CHEMBL217324 | agonist | Compound 4h | Ki = 6.3 nM | EC50 = 1.9 +/- 0.7 nM (Eff=81 +/- 8 %) | PMID: 17034117 | |||||||||||||
CHEMBL217402 | agonist | Compound 4g | Ki = 7.4 nM | EC50 = 2.2 +/- 0.4 nM (Eff=77 +/- 13%) | PMID: 17034117 | |||||||||||||
CHEMBL217769 | agonist | Compound 4k | Ki = 7.1 nM | EC50 = 0.4 +/- 0.1 nM (Eff=107 +/- 5%) | PMID: 17034117 | |||||||||||||
CHEMBL267260 | agonist | Compound 4l | Ki = 7.1 nM | EC50 = 2.8 +/- 1.6 nM (Eff=99 +/- 13%) | PMID: 17034117 | |||||||||||||
CHEMBL277378 | agonist | Compound 4d | Ki = 4.4 nM | EC50 = 2.1 +/- 0.3 nM (Eff=94 +/- 19%) | PMID: 17034117 | |||||||||||||
CHEMBL442240 | agonist | Compound 4e | Ki = 64 nM | EC50 = 1.5 +/- 0.2 nM (Eff=72 +/- 5%) | PMID: 17034117 | |||||||||||||
ZINC08585918 | agonist | BCH | IC50 = 163 nM | PMID: 17149866 | ||||||||||||||
CHEMBL218809 | antagonist | Compound 4b | Ki = 24 nM | IC50 = 260 nM | PMID: 17181141 | |||||||||||||
CHEMBL218914 | agonist | Compound (+/-)10b | Ki = 5.5 nM | EC50 = 6.3 nM (Eff=101%) | PMID: 17181141 | |||||||||||||
CHEMBL219198 | agonist | Compound 7b | Ki = 1.5 nM | EC50 = 320 nM (Eff=65%) | PMID: 17181141 | |||||||||||||
CHEMBL220359 | agonist | Compound (+)10a | Ki = 1.5 nM | EC50 = 281 nM (Eff=63%) | PMID: 17181141 | |||||||||||||
CHEMBL374121 | agonist | Compound 7a | Ki = 1.7 nM | EC50 = 270 nM (Eff=63%) | PMID: 17181141 | |||||||||||||
CHEMBL374781 | agonist | Compound (+/-)10a | Ki = 3.5 nM | EC50 = 4.4 nM (Eff=96%) | PMID: 17181141 | |||||||||||||
CHEMBL384533 | agonist | Compound 4a | Ki = 1.0 nM | EC50 = 385 nM (Eff=85%) | PMID: 17181141 | |||||||||||||
ZINC13540519 | agonist | cortisol | IC50 = 116 +/- 9.8 µM | EC50 = 39.3 +/- 9.7 µM | PMID: 17223690 | GR | ||||||||||||
CHEMBL243137 | antagonist | Compound 9m | Ki = 36 +/- 14 nM | IC50 = 58 +/- 9 nM (Eff=76 +/- 2%) | PMID: 17257838 | |||||||||||||
CHEMBL243351 | antagonist | Compound 10c | Ki = 30 nM | IC50 = 42 nM (Eff=79%) | PMID: 17257838 | |||||||||||||
CHEMBL244827 | antagonist | Compound 9a | Ki = 83 +/- 7 nM | IC50 = 30 +/- 7 nM (Eff=79 +/- 5%) | PMID: 17257838 | |||||||||||||
CHEMBL244828 | antagonist | Compound 9b | Ki =29 +/- 9 nM | IC50 = 35 +/- 10 nM (Eff=77 +/- 2%) | PMID: 17257838 | |||||||||||||
CHEMBL389366 | antagonist | Compound 9d | Ki = 79 +/- 27 nM | IC50 = 56 +/- 10nM (Eff=87 +/- 1%) | PMID: 17257838 | |||||||||||||
CHEMBL396209 | antagonist | Compound 13g | Ki = 56 nM | IC50 = 27 nM (Eff=72%) | PMID: 17257838 | |||||||||||||
CHEMBL396732 | antagonist | Compound 11a | Ki = 30 nM | IC50 = 76 +/- 7 nM (Eff=75 +/- 1%) | PMID: 17257838 | |||||||||||||
CHEMBL441152 | antagonist | Compound 13e | Ki = 74 nM | IC50 = 42 +/- 8 nM (Eff=82 +/- 2%) | PMID: 17257838 | |||||||||||||
ZINC14968401 | agonist | Compound 6c | Ki = 0.5 nM | EC50 = 0.4 +/- 0.1 nM (Eff=74 +/- 7%) | PMID: 17267219 | |||||||||||||
ZINC14968405 | agonist | Compound 6d | Ki = 2.3 nM | EC50 = 0.4 +/- 0 nM (Eff=110 +/- 7 %) | PMID: 17267219 | |||||||||||||
ZINC14968411 | agonist | Compound 6g | Ki = 12 nM | EC50 = 1.3 +/- 0.4 nM (Eff=88 +/- 4 %) | PMID: 17267219 | |||||||||||||
ZINC14968419 | agonist | Compound 6i | Ki = 2.9 nM | EC50 = 0.9 +/- 0.3 nM (Eff=107 +/- 17%) | PMID: 17267219 | |||||||||||||
ZINC14968422 | agonist | Compound 6j | Ki = 12 nM | EC50 = 1.8 +/- 0.5 nM (Eff=81 +/- 10 %) | PMID: 17267219 | |||||||||||||
ZINC14968437 | agonist | Compound 6m | Ki = 1.7 nM | EC50 = 0.2 +/- 0.1 nM (Eff=84 +/- 7%) | PMID: 17267219 | |||||||||||||
ZINC14968441 | agonist | Compound 6n | Ki = 2.6 nM | EC50 = 0.5 +/- 0.1 nM (Eff=88 +/- 14%) | PMID: 17267219 | |||||||||||||
ZINC14968445 | agonist | Compound 6o | Ki = 6.0 +/- 1.1 nM | EC50 = 1.6 +/- 0.8 nM (Eff=67 +/- 7%) | PMID: 17267219 | |||||||||||||
ZINC14968492 | agonist | Compound 7b | Ki = 1.4 nM | EC50 = 0.8 +/- 0.3 nM (Eff=93 +/- 5%) | PMID: 17267219 | |||||||||||||
ZINC14968500 | antagonist | Compound 7d | Ki = 42 nM | IC50 = 36 +/- 15 (Eff=83 +/- 1%) | PMID: 17267219 | |||||||||||||
ZINC14968508 | agonist | Compound7f | Ki = 0.4 nM | EC50 = 0.5 +/- 0.1 nM (Eff=97 +/- 4%) | PMID: 17267219 | |||||||||||||
ZINC14968511 | agonist | Compound 7g | Ki = 0.5 nM | EC50 = 0.89 +/- 0.58 nM (Eff=115 +/- 13%) | PMID: 17267219 | |||||||||||||
ZINC14968515 | agonist | Compound 7h | Ki = 0.5 nM | EC50 = 1.0 +/- 0.0 nM (Eff=125 +/- 22 %) | PMID: 17267219 | |||||||||||||
ZINC14968531 | agonist | Compound 8a | Ki = 9.2 nM | EC50 = 2.3 +/- 0.7 nM (Eff=86 +/- 5%) | PMID: 17267219 | |||||||||||||
ZINC14968544 | agonist | Compound9 | Ki = 12 nM | EC50 = 3.2 +/- 1.3 nM (Eff=71 +/- 5%) | PMID: 17267219 | |||||||||||||
ZINC03938678 | agonist | Compound 20 | Ki = 2.1 nM | EC50 = 0.7 nM | PMID: 17292608 | |||||||||||||
ZINC14967191 | agonist | Compound 1 | Ki = 3.2 nM | EC50 = 2.3 nM | PMID: 17292608 | |||||||||||||
ZINC28704363 | agonist | Compound 7 | Ki = 21 nM | EC50 = 6.2 nM | PMID: 17292608 | |||||||||||||
ZINC28704370 | agonist | Compound 9 | Ki = 24 nM | EC50 = 98 nM | PMID: 17292608 | |||||||||||||
ZINC28704373 | agonist | Compound 11 | Ki = 1.5 nM | EC50 = 2.8 nM | PMID: 17292608 | |||||||||||||
ZINC28704375 | agonist | Compound 12 | Ki = 48 nM | EC50 = 345 nM | PMID: 17292608 | |||||||||||||
ZINC28704376 | agonist | Compound 13 | Ki = 8.5 nM | EC50 = 52 nM | PMID: 17292608 | |||||||||||||
ZINC28704378 | agonist | Compound 14 | Ki = 4.5 nM | EC50 = 1.7 nM | PMID: 17292608 | |||||||||||||
ZINC28704381 | agonist | Compound 16 | Ki = 2.9 nM | EC50 = 3.6 nM | PMID: 17292608 | |||||||||||||
ZINC28704384 | agonist | Compound 18 | Ki = 3.7 nM | EC50 = 487 nM | PMID: 17292608 | |||||||||||||
ZINC28704386 | agonist | Compound 19 | Ki = 1.3 nM | EC50 = 1.7 nM | PMID: 17292608 | |||||||||||||
ZINC28704387 | agonist | Compound 21 | Ki = 1.2 nM | EC50 = 0.6 nM | PMID: 17292608 | |||||||||||||
ZINC28704389 | agonist | Compound 22 | Ki = 8.0 nM | EC50 = 2.2 nM | PMID: 17292608 | |||||||||||||
ZINC28704391 | agonist | Compound 23 | Ki = 4.3 nM | EC50 = 47 nM | PMID: 17292608 | |||||||||||||
ZINC28704393 | agonist | Compound 24 | Ki = 3.0 nM | EC50 = 1.0 nM | PMID: 17292608 | |||||||||||||
ZINC28704396 | agonist | Compound 26 | Ki = 6.1 nM | EC50 = 607 nM | PMID: 17292608 | |||||||||||||
ZINC28704398 | agonist | Compound 27 | Ki = 0.7 nM | EC50 = 1.7 nM | PMID: 17292608 | |||||||||||||
ZINC28704399 | agonist | Compound 28 | Ki = 8.1 nM | EC50 = 221 nM | PMID: 17292608 | |||||||||||||
ZINC28704403 | agonist | Compound 30 | Ki = 14 nM | EC50 = 79 nM | PMID: 17292608 | |||||||||||||
ZINC28704405 | agonist | Compound 31 | Ki = 3.3 nM | EC50 = 36 nM | PMID: 17292608 | |||||||||||||
ZINC28655077 | antagonist | Compound 15 | RBA = 36 % | AntiPRolif. Activ. = 97 % | PMID: 17336533 | |||||||||||||
ZINC28817160 | antagonist | Compound 44 | PMID: 17337185 | |||||||||||||||
ZINC03821119 | agonist | LGD121071 | Ki = 11 +/- 2 nM | EC50 = 4.1 +/- 0.9 nM (Eff=100 +/- 7 %) | PMID: 17439112 | |||||||||||||
ZINC03875484 | agonist | fluoxymesterone | Ki = 5.7 +/- 0.2 nM | EC50 = 0.3 +/- 0.1 nM (Eff= 124 +/- 9%) | PMID: 17439112 | |||||||||||||
ZINC14967266 | agonist | Compound 10b | Ki = 1.2 +/- 0.4 nM | EC50 = 6.4 +/- 1.7 nM (Eff=92 +/- 8%) | PMID: 17439112 | |||||||||||||
ZINC14967270 | agonist | Compound 10c | Ki = 9.6 +/- 7.1 nM | EC50 = 2.4 +/- 0.3 nM (Eff=83 +/- 8%) | PMID: 17439112 | |||||||||||||
ZINC14967281 | agonist | Compound 10f | Ki = 4.0 +/- 1.0 nM | EC50 = 3.5 +/- 1.3 nM (Eff= 88 +/- 5%) | PMID: 17439112 | |||||||||||||
ZINC14967285 | agonist | Compound 12a | Ki = 1.6 +/- 0.2 nM | EC50= 1.4 +/- 0.3 nM (Eff=68 +/- 5%) | PMID: 17439112 | |||||||||||||
ZINC14967289 | antagonist | Compound 12b | Ki = 206 +/- 17 nM | IC50 = 244 +/- 44 nM (Eff=90 +/- 2%) | PMID: 17439112 | |||||||||||||
ZINC14967304 | agonist | Compound (-)-10h | Ki = 25 +/- 4 nM | EC50= 7.8 +/- 0.6 nM (Eff=82 +/- 3%) | PMID: 17439112 | |||||||||||||
ZINC14967315 | agonist | Compound 10 j | Ki = 34 +/- 7 nM | EC50 = 31 +/- 3 nM (Eff=53 +/- 2%) | PMID: 17439112 | |||||||||||||
ZINC14967330 | agonist | Compound 15a | Ki = 113 +/- 50 nM | EC50 = 133 +/- 9 nM (Eff=80 +/- 3%) | PMID: 17439112 | |||||||||||||
ZINC14967349 | agonist | Compound 16b | Ki = 5.6 +/- 1.6 nM | EC50 = 3.9 +/- 2.0 nM (Eff=80 +/- 20%) | PMID: 17439112 | |||||||||||||
ZINC14967356 | agonist | Compound 16c | Ki = 4.0 +/- 0.9 nM | EC50 = 1.9 +/- 0.3 nM (Eff=65 +/- 5%) | PMID: 17439112 | |||||||||||||
ZINC14967372 | agonist | Compound (R)-16e | Ki = 7.1 +/- 1.9 nM | EC50 = 1.1 +/- 0.2 nM (Eff=82 +/- 5%) | PMID: 17439112 | |||||||||||||
ZINC14967383 | agonist | Compound (R)-16g | Ki = 51 +/- 36 nM | EC50 = 5.9 +/- 0.4 nM (Eff=46 +/- 23%) | PMID: 17439112 | |||||||||||||
ZINC14967386 | agonist | Compound (R)-16h | Ki = 109 +/- 52 nM | EC50 = 27 +/- 13 nM (Eff=65 +/- 15%) | PMID: 17439112 | |||||||||||||
ZINC14967390 | agonist | Compound (R)-27 | Ki = 27 nM | EC50 = 26 +/- 14 nM (Eff=46 +/- 13%) | PMID: 17439112 | |||||||||||||
ZINC14967398 | agonist | Compound 28 | Ki = 16 +/- 11 nM | EC50 =14 +/- 4 nM (Eff=75 +/- 5%) | PMID: 17439112 | |||||||||||||
ZINC33818834 | antagonist | ganoderol B | PMID: 17499997 | |||||||||||||||
ZINC13982538 | agonist | Compound 11a | Ki = 0.9 nM | EC50 = 1.8 nM | PMID: 17552509 | |||||||||||||
ZINC14967206 | agonist | Compound 8 | Ki = 2 nM | EC50 = 15 nM | PMID: 17552509 | |||||||||||||
ZINC14967209 | agonist | Compound 9 | Ki = 2.2 nM | EC50 = 20 nM | PMID: 17552509 | |||||||||||||
ZINC14967213 | agonist | Compound 10a | Ki = 1.5 nM | EC50 = 5.2 nM | PMID: 17552509 | |||||||||||||
ZINC14967217 | agonist | Compound 12a | Ki = 0.9 nM | EC50 = 2.5 nM | PMID: 17552509 | |||||||||||||
ZINC14967221 | agonist | Compound 10b | Ki = 4.0 nM | EC50 = 87 nM | PMID: 17552509 | |||||||||||||
ZINC14967225 | agonist | Compound 11b | Ki =1.6 nM | EC50 = 7.1 nM | PMID: 17552509 | |||||||||||||
ZINC14967229 | agonist | Compound 12b | Ki =1.9 nM | EC50 = 48 nM (Eff=65%) | PMID: 17552509 | |||||||||||||
ZINC14967233 | agonist | Compound10c | Ki = 2.9 nM | EC50 = 13 nM | PMID: 17552509 | |||||||||||||
ZINC14967237 | agonist | Compound11c | Ki = 0.7 nM | EC50 = 2.6 nM | PMID: 17552509 | |||||||||||||
ZINC14967241 | agonist | Compound 12c | Ki = 1.0 nM | EC50 = 2.9 nM | PMID: 17552509 | |||||||||||||
ZINC14967244 | agonist | Compound 11d | Ki = 2.3 nM | EC50 = 7.4 nM | PMID: 17552509 | |||||||||||||
ZINC14967248 | agonist | Compound 12d | Ki = 2.2 nM | EC50 = 2.1 nM | PMID: 17552509 | |||||||||||||
ZINC14967251 | agonist | Compound 13 | Ki = 23 nM | EC50 = 108 nM (Eff= 75%) | PMID: 17552509 | |||||||||||||
ZINC14967255 | agonist | Compound 14 | Ki = 0.5 nM | EC50 = 2.0 nM | PMID: 17552509 | |||||||||||||
CHEMBL233773 | agonist | Compound 3a | Ki = 0.45 nM | EC50 = 11.9 nM | PMID: 17574413 | |||||||||||||
CHEMBL391770 | agonist | Compound 4b | Ki = 20 nM | EC50 = 8962 nM | PMID: 17574413 | |||||||||||||
ZINC28822679 | agonist | Compound 3c | Ki = 8.2 nM | EC50 = 1251 nM | PMID: 17574413 | |||||||||||||
ZINC28822680 | agonist | Compound 3d | Ki = 44 nM | EC50 = 3517 nM | PMID: 17574413 | |||||||||||||
ZINC28822687 | agonist | Compound 4c | Ki = 14 nM | EC50 =7729 nM | PMID: 17574413 | |||||||||||||
ZINC00538159 | antagonist | periciazine | Ki = 3.0 µM | PMID: 17606915 | ||||||||||||||
ZINC19203912 | antagonist | fluphenazine | Ki = 0.8 µM | PMID: 17606915 | ||||||||||||||
ZINC03945835 | agonist | Compound 18h | EC50 = 1 +/- 0.4 nM (Eff=92 +/- 5%) | PMID: 17703938 | PR | |||||||||||||
ZINC28953727 | antagonist | Compound 16b | IC50 = 72 nM (Eff=64%) | PMID: 17703938 | ||||||||||||||
ZINC28953800 | agonist | Compound 18o | EC50 =20 +/- 16 nM (Eff=74 +/- 5%) | PMID: 17703938 | ||||||||||||||
ZINC28953810 | antagonist | Compound 18t | IC50 = 45 +/- 10 nM (Eff=88 +/- 2%) | PMID: 17703938 | ||||||||||||||
ZINC16052389 | agonist | EM5744 | RBA = 525% | PMID: 17711855 | ||||||||||||||
ZINC14968195 | antagonist | Compound 4a | Ki = 1700 nM | IC50 = 25 +/- 20 nM (Eff=58 +/- 7%) | PMID: 17887661 | |||||||||||||
ZINC14968204 | agonist | Compound 4b | Ki = 72 nM | EC50 = 13 nM (Eff=39 +/- 11%) | PMID: 17887661 | |||||||||||||
ZINC14968208 | agonist | Compound 4c | Ki = 19 nM | EC50 = 2.6 +/- 0.8 nM (Eff=101 +/-14 %) | PMID: 17887661 | |||||||||||||
ZINC14968216 | agonist | Compound 4e | Ki = 70 nM | EC50 = 21 +/- 3 nM (Eff=71 +/- 9%) | PMID: 17887661 | |||||||||||||
ZINC14968220 | agonist | Compound 4f | Ki = 10 nM | EC50 = 12 +/- 0.2 nM (Eff=101 +/- 5%) | PMID: 17887661 | |||||||||||||
ZINC14968224 | agonist | Compound 6a | Ki = 1.5 +/- 0.2 nM | EC50 = 7.1 +/- 0.4 nM (Eff=109 +/- 13%) | PMID: 17887661 | |||||||||||||
ZINC03814430 | antagonist | spironolactone | Ki = 39.4 nM | IC50 = 523 nM | PMID: 18038968 PMID: 20672822 | |||||||||||||
CHEMBL255216 | antagonist | Compound 28 | Ki = 18 nM | IC50 = 88 nM | PMID: 18291644 | |||||||||||||
CHEMBL255776 | antagonist | Compound 2 | Ki = 21 nM | IC50 = 130 nM | PMID: 18291644 | |||||||||||||
CHEMBL257668 | antagonist | Compound 21 | Ki = 3.0 nM | IC50 = 16 nM | PMID: 18291644 | |||||||||||||
CHEMBL271261 | antagonist | Compound 26 | Ki = 27 nM | IC50 = 70 nM | PMID: 18291644 | |||||||||||||
CHEMBL271262 | antagonist | Compound 25 | Ki = 17 nM | IC50 = 120 nM | PMID: 18291644 | |||||||||||||
CHEMBL272509 | antagonist | Compound 20 | Ki = 3.0 nM | IC50 = 19 nM | PMID: 18291644 | |||||||||||||
CHEMBL403039 | antagonist | Compound 29 | Ki = 17 nM | IC50 = 40 nM | PMID: 18291644 | |||||||||||||
CHEMBL403061 | antagonist | Compound 24 | Ki = 12 nM | IC50 = 20 nM | PMID: 18291644 | |||||||||||||
CHEMBL403213 | antagonist | Compound 23 | Ki = 4.0 nM | IC50 = 38 nM | PMID: 18291644 | |||||||||||||
CHEMBL403214 | antagonist | Compound 22 | Ki = 17 nM | IC50 = 11 nM | PMID: 18291644 | |||||||||||||
CHEMBL403669 | antagonist | Compound 18 | Ki = 17 nM | IC50 = 7.0 nM | PMID: 18291644 | |||||||||||||
CHEMBL446626 | antagonist | Compound 27 | Ki = 3.0 nM | IC50 = 16 nM | PMID: 18291644 | |||||||||||||
ZINC02068322 | antagonist | Compound 1 | Ki = 360 nM | IC50 = 152 nM | PMID: 18291644 | |||||||||||||
ZINC03948653 | antagonist | Compound 3 | Ki = 40 nM | IC50 = 774 nM | PMID: 18291644 | |||||||||||||
ZINC29126975 | antagonist | Compound 14 | Ki = 1170 nM | IC50 = 2860 nM | PMID: 18291644 | |||||||||||||
ZINC29127116 | antagonist | Compound 12 | Ki = 692 nM | IC50 = 1150 nM | PMID: 18291644 | |||||||||||||
ZINC29127118 | antagonist | Compound 13 | Ki = 1110 nM | IC50 = 3310 nM | PMID: 18291644 | |||||||||||||
ZINC29127159 | antagonist | Compound 11 | Ki = 77.0 nM | IC50 = 500 nM | PMID: 18291644 | |||||||||||||
ZINC29127210 | antagonist | Compound 10 | Ki = 486 nM | IC50 = 2290 nM | PMID: 18291644 | |||||||||||||
ZINC29127216 | antagonist | Compound 9 | Ki = 377 nM | IC50 = 480 nM | PMID: 18291644 | |||||||||||||
ZINC29127280 | antagonist | Compound 8 | Ki = 221 nM | IC50 = 350 nM | PMID: 18291644 | |||||||||||||
ZINC29127399 | antagonist | Compound 7 | Ki =53.0 nM | IC50 = 670 nM | PMID: 18291644 | |||||||||||||
ZINC00899824 | antagonist | Curcumin | EC50 = 35.0 µM | PMID: 18316193 | ||||||||||||||
ZINC04214779 | antagonist | Vitamin E succinate | EC50 = 38.0 µM | PMID: 18316193 | ||||||||||||||
ZINC03936191 | antagonist | asoprisnil | IC50 = 6.1 nM | PMID: 18318463 | PR | |||||||||||||
ZINC12496366 | agonist | tetrahydrogestrinone | EC50 = 4.3 nM | PMID: 18395441 | ||||||||||||||
CHEMBL256330 | agonist | Compound (+/-)-33 | Ki = 8.3 +/- 1.6 nM | EC50 = 5.9 +/- 1.2 nM (Eff=104 +/- 7 %) | PMID: 18400499 | |||||||||||||
ZINC29044405 | agonist | Compound (+/-)-10 | EC50 = 3.2 nM (Eff=61%) | PMID: 18400499 | ||||||||||||||
ZINC29045788 | antagonist | Compound (+)-(S)-29b | IC50 = 44 nM (Eff=86%) | PMID: 18400499 | ||||||||||||||
ZINC29045982 | antagonist | Compound (+)-(S)-28b | Ki = 180 nM | IC50 = 574 +/- 156 nM (Eff=91 +/- 7%) | PMID: 18400499 | |||||||||||||
ZINC34799936 | agonist | Compound (-)-(R)-21a | Ki = 18 nM | EC50 = 23 +/- 6 nM (Eff=51 +/- 3%) | PMID: 18400499 | |||||||||||||
ZINC13919812 | agonist | Compound 4c | IC50 = 26 nM | EC50 = 13 nM | PMID: 21944856 | |||||||||||||
ZINC34022720 | agonist | Compound 1 | IC50 = 5.1 nM | EC50 = 2.3 nM | PMID: 21944856 | |||||||||||||
ZINC03814366 | agonist | 11-β-hydroxytestosterone | PMID: 18514531 | |||||||||||||||
CHEMBL480182 | antagonist | ISOP-4 | IC50 = 0.4 µM | PMID: 18571420 | ||||||||||||||
ZINC40411224 | antagonist | Compound 54 | Ki = 0.37 µM | IC50 = 4.9 µM | PMID: 18571420 | |||||||||||||
ZINC40411803 | antagonist | Compound 45 | Ki = 0.17 +/- 0.06 µM | IC50 = 2.1 +/- 0.1 µM | PMID: 18571420 | |||||||||||||
ZINC40412128 | antagonist | Compound 50 | Ki = 0.11 +/- 0.01 µM | IC50 = 1.7 +/- 0.1 µM | PMID: 18571420 | |||||||||||||
ZINC40412441 | antagonist | Compound 39 | Ki = 0.14 +/- 0.05 µM | IC50 = 2.0 +/- 0.8 µM | PMID: 18571420 | |||||||||||||
ZINC40412585 | antagonist | Compound 40 | Ki = 0.18 +/- 0.04 µM | IC50 = 6.1 +/- 3.1 µM | PMID: 18571420 | |||||||||||||
ZINC40413281 | antagonist | Compound 17 | Ki = 2.2 +/- 1.8 µM | IC50 = 5.8 +/- 0.2 µM | PMID: 18571420 | |||||||||||||
ZINC40414110 | antagonist | Compound 13 | Ki = 2.7 +/- 1.6 µM | IC50 = 10 µM | PMID: 18571420 | |||||||||||||
ZINC40414183 | antagonist | Compound 47 | Ki = 0.22 µM | IC50 = 1.95 µM | PMID: 18571420 | |||||||||||||
ZINC40933232 | antagonist | Compound 26 | Ki = 1.8 +/- 0.5 µM | IC50 = 5.5 +/- 2.6 µM | PMID: 18571420 | |||||||||||||
ZINC40933552 | antagonist | Compound 53 | Ki = 0.34 µM | IC50 = 3.7 µM | PMID: 18571420 | |||||||||||||
ZINC40934004 | antagonist | Compound 48 | Ki = 0.10 +/- 0.01 µM | IC50 = 0.99 +/- 0.59 µM | PMID: 18571420 | |||||||||||||
ZINC40934571 | antagonist | Compound 19 | Ki = 2.0 +/- 0.5 µM | IC50 = 15.5 +/- 3.5 µM | PMID: 18571420 | |||||||||||||
ZINC40935185 | antagonist | Compound 22 | Ki = 0.11 +/- 0.02 µM | IC50 = 0.44 +/- 0.08 µM | PMID: 18571420 | |||||||||||||
ZINC40935219 | antagonist | Compound 16 | Ki = 0.69 +/- 0.05 µM | IC50 = 6.6 +/- 4.8 µM | PMID: 18571420 | |||||||||||||
ZINC40935758 | antagonist | Compound 37 | Ki = 0.13 +/- 0.06 µM | IC50 = 0.61 +/- 0.23 µM | PMID: 18571420 | |||||||||||||
ZINC40936060 | antagonist | Compound 44 | Ki = 0.18 +/- 0.015 µM | IC50 = 0.95 +/- 0.28 µM | PMID: 18571420 | |||||||||||||
ZINC40936768 | antagonist | Compound 21 | Ki = 0.52 +/- 0.42 µM | IC50 = 0.88 +/- 0.18 µM | PMID: 18571420 | |||||||||||||
ZINC40981295 | antagonist | Compound 9 | Ki = 3.1 +/- 1.0 µM | IC50 = 15.0 +/- 0.2 µM | PMID: 18571420 | |||||||||||||
ZINC03812944 | antagonist | flutamide | RBA = 13.7 % | IC50 = 58 µM | PMID: 18707892 | |||||||||||||
ZINC40379364 | antagonist | Compound 25 | IC50 = 0.73 µM | PMID: 19138519 | ||||||||||||||
ZINC40407981 | antagonist | Compound 13 | IC50 = 18.9 µM | PMID: 19138519 | ||||||||||||||
ZINC40845169 | antagonist | Compound 11 | IC50 = 10.0 µM | PMID: 19138519 | ||||||||||||||
ZINC40859808 | antagonist | Compound 40 | IC50 = 1.9 µM | PMID: 19138519 | ||||||||||||||
ZINC40898749 | antagonist | Compound 10 | IC50 = 25.8 µM | PMID: 19138519 | ||||||||||||||
ZINC40914516 | antagonist | Compound 5 | IC50 = 7.7 µM | PMID: 19138519 | ||||||||||||||
ZINC36435471 | antagonist | ganoderic acid DM | IC50 = 10.6 µM | PMID: 19289282 | ||||||||||||||
CHEMBL483746 | antagonist | Compound 11 | Ki = 10 +/- 2 nM | IC50 = 1800 nM | PMID: 19351168 | |||||||||||||
ZINC13982536 | agonist | Compound 6c | Ki = 0.3 +/- 0.1 nM | EC50 = 0.2 +/- 0.1 nM | PMID: 19351168 | |||||||||||||
ZINC34554150 | agonist | Compound 6f | Ki = 0.3 +/- 0.1 nM | EC50 = 1.4 +/- 0.2 nM | PMID: 19351168 | |||||||||||||
ZINC40410391 | agonist | Compound 15 | Ki = 17 nM | EC50 = 1109 nM | PMID: 19351168 | |||||||||||||
ZINC40410424 | agonist | Compound 6d | Ki = 0.2 +/- 0.5 nM | EC50 = 19 +/- 3 nM | PMID: 19351168 | |||||||||||||
ZINC40412674 | agonist | Compound 6b | Ki = 0.3 +/- 0.1 nM | EC50 = 14 +/- 0.5 nM | PMID: 19351168 | |||||||||||||
ZINC40420358 | agonist | Compound 6g | Ki = 0.7 +/- 0.2 nM | EC50 = 3.7 +/- 0.6 nM | PMID: 19351168 | |||||||||||||
ZINC40938487 | agonist | Compound 6a | Ki = 0.8 +/- 0.5 nM | EC50 = 4.8 +/- 0.6 nM | PMID: 19351168 | |||||||||||||
ZINC40943002 | agonist | Compound 6e | Ki = 2.3 +/- 0.3 nM | EC50 = 1.1 +/- 0.1 nM | PMID: 19351168 | |||||||||||||
ZINC53195704 | agonist | Compound 12 | Ki = 1.9 +/- 0.1 nM | EC50 = 44 nM | PMID: 19351168 | |||||||||||||
ZINC34270438 | agonist | Compound 20 | IC50 = 62 nM | EC50 = 62 nM (Eff=93%) | PMID: 19606870 | |||||||||||||
ZINC38459796 | agonist | Compound 21 | IC50 = 59 nM | EC50 = 17 nM (Eff=141%) | PMID: 19606870 | |||||||||||||
ZINC38476923 | agonist | Compound 17 | IC50 = 35 nM | EC50 = 17 nM (Eff=92%) | PMID: 19606870 | |||||||||||||
ZINC38477862 | agonist | Compound 16 | IC50 = 116 nM | EC50 = 26 nM (Eff=140%) | PMID: 19606870 | |||||||||||||
ZINC62179083 | agonist | Compound 2 | IC50 = 7 nM | EC50 = 5 nM (Eff=105%) | PMID: 19606870 | |||||||||||||
ZINC42923032 | antagonist | Compound 1 | IC50 (LNCaP)= 20.6 µM | PMID: 19725582 | ||||||||||||||
ZINC42989367 | antagonist | Compound 10 | IC50 (LNCaP) = 2.3 µM | PMID: 19725582 | ||||||||||||||
ZINC43014319 | antagonist | Compound 9 | IC50 (LNCaP)= 8.7 µM | PMID: 19725582 | ||||||||||||||
ZINC43016162 | antagonist | Compound 11 | IC50 (LNCaP) = 8.5 µM | PMID: 19725582 | ||||||||||||||
ZINC43059632 | antagonist | Compound 6 | IC50 (LNCaP) = 1.3 µM | PMID: 19725582 | ||||||||||||||
ZINC43076001 | antagonist | Compound 8 | IC50 (LNCaP) = 4.5 µM | PMID: 19725582 | ||||||||||||||
ZINC43120013 | antagonist | Compound 3 | IC50 (LNCaP) = 6.2 µM | PMID: 19725582 | ||||||||||||||
ZINC03814395 | agonist | levonorgestrel | EC50 = 0.6635 +/- 0.02237 nM | PMID: 19836445 | ||||||||||||||
ZINC03814419 | agonist | norethynodrel | EC50 = 34.96 +/- 35.18 nM | PMID: 19836445 | ER_alpha | |||||||||||||
ZINC03814422 | agonist | 17-α-methyltestosterone | EC50 = 0.05841 +/- 0.08863 nM | PMID: 19836445 | ||||||||||||||
ZINC03814429 | agonist | trenbolone | PMID: 20138077 | |||||||||||||||
ZINC00001411 | antagonist | eugenol | IC50 = 19 +/- 7 µM | PMID: 20226658 | ||||||||||||||
ZINC00154632 | antagonist | raspberry ketone | IC50 = 252 +/- 26 µM | PMID: 20226658 | ||||||||||||||
ZINC00526834 | antagonist | zingerone | IC50 = 153 + / - 8 µM | PMID: 20226658 | ||||||||||||||
ZINC02558108 | antagonist | P-hydroxyphenylacetone | IC50 = 420 +/- 120 µM | PMID: 20226658 | ||||||||||||||
ZINC35968242 | antagonist | Commpound 32-d | IC50 = 440 nM | IC50 = 190 nM | PMID: 20381361 | |||||||||||||
ZINC49781439 | antagonist | Commpound 18a | IC50 = 400 nM | IC50 = 64 nM | PMID: 20381361 | |||||||||||||
ZINC49781440 | antagonist | Commpound 24 | IC50 = 170 nM | IC50 = 64 nM | PMID: 20381361 | |||||||||||||
ZINC58502022 | antagonist | Compound 19 | Ki = 84 nM | IC50 = 129 nM (Inh=95%) | PMID: 20584610 | |||||||||||||
ZINC58502133 | antagonist | Compound 21 | Ki = 36 nM | IC50 = 69 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58502138 | antagonist | Compound 27 | Ki = 98 nM | IC50 = 876 nM (Inh=88%) | PMID: 20584610 | |||||||||||||
ZINC58502258 | antagonist | Compound 28 | Ki = 40 nM | IC50 = 16 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58502291 | antagonist | Compound 32 | Ki = 12 nM | IC50 = 54 nM (Inh=100%) | PMID: 20584610 | |||||||||||||
ZINC58506139 | antagonist | Compound 18 | Ki = 14 nM | IC50 = 14 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58506159 | antagonist | Compound 24 | Ki = 6.6 nM | IC50 = 9.3 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58506218 | antagonist | Compound 22 | Ki = 23 nM | IC50 = 54 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58506233 | antagonist | Compound 20 | Ki = 39 nM | IC50 = 215 nM (Inh=98%) | PMID: 20584610 | |||||||||||||
ZINC58506371 | antagonist | Compound 23 | Ki = 5.7 nM | IC50 = 65 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58506557 | antagonist | Compound 30 | Ki = 56 nM | IC50 = 205 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58506653 | antagonist | Compound 31 | Ki = 16 nM | IC50 = 85 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58511425 | antagonist | Compound 34 | Ki = 93 nM | IC50 = 170 nM (Inh=98%) | PMID: 20584610 | |||||||||||||
ZINC58512299 | antagonist | Compound 38 | Ki = 3.5 nM | IC50 = 11 nM (Inh=98%) | PMID: 20584610 | |||||||||||||
ZINC58520321 | antagonist | Compound 29 | Ki = 29 nM | IC50 = 39 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58541168 | antagonist | Compound 36 | Ki = 22 nM | IC50 = 37 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58575413 | antagonist | Compound 39 | Ki = 6.1 nM | IC50 = 31 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58576392 | antagonist | Compound 37 | Ki = 9.4 nM | IC50 = 7.4 nM (Inh=96%) | PMID: 20584610 | |||||||||||||
ZINC58599325 | antagonist | Compound 13 | Ki = 50 nM | IC50 = 873 nM | PMID: 20584610 | |||||||||||||
ZINC58599368 | antagonist | Compound 15 | Ki = 14 nM | IC50 = 32 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58602712 | antagonist | Compound 16 | Ki = 37 nM | IC50 = 182 nM (Inh=97%) | PMID: 20584610 | |||||||||||||
ZINC58602845 | antagonist | Compound 35 | Ki = 9.0 nM | IC50 = 7.4 nM (Inh=98%) | PMID: 20584610 | |||||||||||||
ZINC58603138 | antagonist | Compound 25 | Ki = 11 nM | IC50 = 12 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58603260 | antagonist | Compound 26 | Ki = 176 nM | IC50 = 313 nM (Inh=97%) | PMID: 20584610 | |||||||||||||
ZINC58603299 | antagonist | Compound 17 | Ki = 3.7 nM | IC50 = 24 nM (Inh=99%) | PMID: 20584610 | |||||||||||||
ZINC58655555 | antagonist | Compound 33 | Ki = 32 nM | IC50 = 54 nM (Inh=100%) | PMID: 20584610 | |||||||||||||
ZINC64361274 | antagonist | Compound 18 | IC50 = 3 µM | PMID: 20826091 | ||||||||||||||
ZINC28528431 | antagonist | Compound (R,S)-2 | Ki = 1100 nM | IC50 = 68 nM | PMID: 20888766 | VDR | ||||||||||||
ZINC28528430 | antagonist | Compound (S,S)-2 | Ki = 1100 nM | IC50 = 13 nM | PMID: 20888766 | VDR | ||||||||||||
ZINC28528433 | antagonist | Compound (R,R)-2 | Ki = 1000 nM | IC50 = 14 nM | PMID: 20888766 | VDR | ||||||||||||
ZINC28528432 | antagonist | Compound (S,R)-2 | Ki = 1000 nM | IC550 = 3.0 nM | PMID: 20888766 | VDR | ||||||||||||
ZINC64503983 | antagonist | Compound 16b | IC50 = 0.88 µM | PMID: 20888766 | ||||||||||||||
ZINC64504070 | antagonist | Compound 16c | IC50 = 0.13 µM | PMID: 20888766 | ||||||||||||||
ZINC64512502 | antagonist | Compound 15c | IC50 = 9.8 µM | PMID: 20888766 | ||||||||||||||
ZINC64512813 | antagonist | Compound (S)-3 | Ki = 1800 nM | IC50 = 32 nM | PMID: 20888766 | |||||||||||||
ZINC64512815 | antagonist | Compound (R)-3 | Ki = 1100 nM | IC50 = 15 nM | PMID: 20888766 | |||||||||||||
ZINC64513793 | antagonist | Compound 15b | IC50 = 1.1 µM | PMID: 20888766 | VDR | |||||||||||||
ZINC64528451 | antagonist | Compound 16a | IC50 = 1.7 µM | PMID: 20888766 | ||||||||||||||
ZINC00016183 | agonist | Commpound 23 | EC5 = 1.0 nM | PMID: 21050768 | ||||||||||||||
ZINC34808313 | antagonist | Commpound 7 | IC50 = 200 nM | PMID: 21050768 | ||||||||||||||
ZINC43197765 | antagonist | Commpound 17b | IC50 = 700 nM | PMID: 21050768 | ||||||||||||||
ZINC35793633 | agonist | Compound 2 | RBA = 5.5 +/- 1.8 % | PMID: 21506597 | ||||||||||||||
ZINC66167073 | antagonist | Compound 7 | RBA = 1.84 +/- 0.7 % | PMID: 21506597 | ||||||||||||||
ZINC71294299 | antagonist | Compound 8 | RBA = 0.37 +/- 0.02 % | PMID: 21506597 | ||||||||||||||
ZINC71295080 | antagonist | Compound 6 | RBA = 0.97 +/- 0.33 % | PMID: 21506597 | ||||||||||||||
ZINC73197915 | antagonist | Compound 4 | Inhibition = 50% | PMID: 22148427 | ||||||||||||||
ZINC03814379 | agonist | nandrolone | PMID: 3865479 | ER_alpha | ||||||||||||||
ZINC03814394 | agonist | gestodene | RBA = 33 % | PMID: 7750284 | PR | |||||||||||||
ZINC03814382 | antagonist | mifepristone (RU486) | Ki = 10.6 +/- 2.9 nM | IC50 = 5 +/- 2 nM (Eff=75 +/- 2%) | PMID: 8627601 |
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ZINC03833829 | antagonist | Compound 27a | Ki = 737 +/- 195 nM | IC50 = 377 +/- 49 nM (Eff=90 +/- 1%) | PMID: 8627601 | |||||||||||||
ZINC03833841 | antagonist | Compound 22a | Ki = 6303 +/- 3708 nM | IC50 = 250 nM (Eff=21%) | PMID: 8627601 | |||||||||||||
ZINC04428529 | antagonist | Progesterone | Ki = 8.5 +/- 3.1 nM | IC50 = 37 +/- 2 nM (Eff=46+/- 7%) | PMID: 8627601 |
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ZINC03831956 | antagonist | Compound 25 | Ki = 5831 +/- 4168 | IC50 = 946 +/- 419 nM (Eff=90 +/- 4%) | PMID: 9464360 | GR | ||||||||||||
ZINC13777087 | antagonist | Compound 13 | Ki = 1856 +/- 251 nM | IC50 = 745 +/- 285 nM (Eff=78 +/- 5%) | PMID: 9464360 | |||||||||||||
ZINC13777101 | antagonist | Compound 18 | Ki = 1526 +/- 360 | IC50 = 253 +/- 156 nM (Eff=88 +/- 8%) | PMID: 9464360 | |||||||||||||
ZINC13777103 | antagonist | Compound 19 | Ki = 2138 +/- 341 | IC50 = 401 +/- 13 nM (Eff=90 +/- 7%) | PMID: 9464360 | |||||||||||||
ZINC13777116 | antagonist | Compound 24 | Ki = 795 +/- 95 | IC50 = 315 +/- 42 nM (Eff=90 +/- 5%) | PMID: 9464360 | |||||||||||||
ZINC13778369 | antagonist | Compound 19g | Ki = 69 +/- 28 nM | IC50 = 48 +/- 4 nM (Eff=85 +/- 1%) | PMID: 9484511 | |||||||||||||
ZINC03814399 | antagonist | Compound 21b | Ki = 17 +/- 4 nM | IC50 = 19 +/- 3 nM (81+/- 3%) | PMID: 9484511 | PR | ||||||||||||
ZINC03814423 | antagonist | cyproterone acetate | Ki = 14 +/- 5 nM | IC50 = 26 +/- 23 nM (Eff=48 +/- 6%) | PMID: 9484511 | |||||||||||||
ZINC13778335 | antagonist | Compound 9d | Ki = 85 +/- 32 nM | IC50 = 22 +/- 4 nM (Eff=78 +/- 2%) | PMID: 9484511 | |||||||||||||
ZINC13778356 | antagonist | Compound 19a | Ki = 81 +/- 17 nM | IC50 = 34 +/- 6 nM (Eff=89 +/- 2%) | PMID: 9484511 | PR | ||||||||||||
ZINC13778384 | antagonist | Compound 29c | Ki = 54 +/- 11 nM | IC50 = 27 +/- 7 nM (Eff=49 +/- 7%) | PMID: 9484511 | |||||||||||||
ZINC13778395 | antagonist | Compound 34 | Ki = 78 +/- 13 nM | IC50 = 27 +/- 5 nM (Eff=85 +/- 2%) | PMID: 9484511 | |||||||||||||
ZINC13778399 | antagonist | Compound 36 | Ki = 86 +/- 51 nM | IC50 =58 +/- 22 nM (Eff=71 +/- 2%) | PMID: 9484511 | PR | ||||||||||||
ZINC13778400 | antagonist | Compound 42 | Ki = 268 +/- 10 nM | IC50 = 68 +/- 4 nM (Eff=84 +/- 3%) | PMID: 9484511 | PR | ||||||||||||
ZINC03814411 | agonist | androstanediol | PMID: 9736693 | |||||||||||||||
ZINC05029557 | agonist | MPA | Ki = 2.9 +/- 0.2 nM | EC50 = 6.1 +/- 1.0 nM (Eff=159 +/- 10%) | PMID: 9784110 | GR | ||||||||||||
CHEMBL162503 | antagonist | Compound 5 | Ki = 61 +/- 18 nM | IC50 = 56 +/- 16 nM (Eff=67 +/- 6%) | PMID: 9871534 | |||||||||||||
CHEMBL163366 | agonist | Compound 8 | Ki = 9 +/- 3 nM | EC50 = 20 +/- 2 nM (Eff=66 +/- 10%) | PMID: 9871534 | |||||||||||||
ZINC03814374 | agonist | Compound 17 | Ki = 4 +/- 1 nM | EC50 = 10 +/- 2 nM (Eff=61 +/- 5%) | PMID: 9871534 | |||||||||||||
ZINC03814376 | agonist | Compound 16 | Ki = 5 +/- 1 nM | EC50 = 5 +/- 1 nM (Eff=91 +/- 6%) | PMID: 9871534 | PR | ||||||||||||
ZINC05141582 | antagonist | Compound 15 | Ki = 33 +/- 7 nM | IC50 = 56 +/- 8 nM (Eff=82 +/- 2%) | PMID: 9871534 | |||||||||||||
ZINC27851181 | agonist | Compound 9 | Ki = 6 +/- 1 nM | EC50 = 5 + /- 1 nM (Eff=8 +/- 6%) | PMID: 9871534 | PR | ||||||||||||
ZINC27854097 | antagonist | Compound 6 | Ki = 167 +/- 31 nM | IC50 = 197 +/- 52 nM (Eff=94 +/- 5%) | PMID: 9871534 | |||||||||||||
ZINC27854105 | antagonist | Compound 29 | Ki = 59 nM | IC50 = 27 +/- 9 nM (Eff=90 +/- 1%) | PMID: 9871534 | |||||||||||||
ZINC49802048 | agonist | Compound 25 | Ki = 9 +/- 2 nM | EC50 = 33 +/- 6 nM (Eff=36 +/- 5%) | PMID: 9871534 | |||||||||||||
ZINC27854723 | agonist | Compound 24 | Ki = 21 +/- 7 nM | EC50 = 25 +/- 2 nM (Eff=60 +/- 9%) | PMID: 9871534 | PR | ||||||||||||
ZINC27854781 | antagonist | Compound 28 | Ki = 79 nM | IC50 =26 +/- 9 nM (Eff=67 +/- 5%) | PMID: 9871534 | |||||||||||||
ZINC27856785 | antagonist | Compound 18 | Ki = 10 +/- 1 nM | IC50 = 36 +/- 12 nM (Eff=73 +/- 6%) | PMID: 9871534 | PR | ||||||||||||
ZINC22446634 | antagonist | acetophenazine | Ki = 0.8 µM | PMID:17606915 |